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Volumn 28, Issue 6, 2012, Pages 631-641

The Biological Role of Inflammation in Atherosclerosis

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; B7 ANTIGEN; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CASPASE 5; CRYOPYRIN; FRACTALKINE; GAMMA INTERFERON; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPASE A2; REACTIVE OXYGEN METABOLITE; RETINOIC ACID INDUCIBLE PROTEIN I; STROMAL CELL DERIVED FACTOR 1; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN D;

EID: 84869095071     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cjca.2012.06.023     Document Type: Review
Times cited : (149)

References (101)
  • 2
    • 0000238931 scopus 로고
    • Pathogenesis of atherosclerosis
    • Duguid J.B. Pathogenesis of atherosclerosis. Lancet 1949, 2:925-927.
    • (1949) Lancet , vol.2 , pp. 925-927
    • Duguid, J.B.1
  • 3
    • 2042425841 scopus 로고
    • The natural history of atherosclerosis; comparison of the early aortic lesions in New Orleans, Guatemala, and Costa Rica
    • Strong J.P., McGill H.C., Tejada C., Holman R.L. The natural history of atherosclerosis; comparison of the early aortic lesions in New Orleans, Guatemala, and Costa Rica. Am J Pathol 1958, 34:731-744.
    • (1958) Am J Pathol , vol.34 , pp. 731-744
    • Strong, J.P.1    McGill, H.C.2    Tejada, C.3    Holman, R.L.4
  • 4
    • 0001460601 scopus 로고
    • The natural history of atherosclerosis: the early aortic lesions as seen in New Orleans in the middle of the of the 20th century
    • Holman R.L., McGill H.C., Strong J.P., Geer J.C. The natural history of atherosclerosis: the early aortic lesions as seen in New Orleans in the middle of the of the 20th century. Am J Pathol 1958, 34:209-235.
    • (1958) Am J Pathol , vol.34 , pp. 209-235
    • Holman, R.L.1    McGill, H.C.2    Strong, J.P.3    Geer, J.C.4
  • 5
    • 0015829488 scopus 로고
    • Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis
    • Ross R., Glomset J.A. Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis. Science 1973, 180:1332-1339.
    • (1973) Science , vol.180 , pp. 1332-1339
    • Ross, R.1    Glomset, J.A.2
  • 6
    • 0017184071 scopus 로고
    • The pathogenesis of atherosclerosis (second of two parts)
    • Ross R., Glomset J.A. The pathogenesis of atherosclerosis (second of two parts). N Engl J Med 1976, 295:420-425.
    • (1976) N Engl J Med , vol.295 , pp. 420-425
    • Ross, R.1    Glomset, J.A.2
  • 7
    • 0017305294 scopus 로고
    • The pathogenesis of atherosclerosis (first of two parts)
    • Ross R., Glomset J.A. The pathogenesis of atherosclerosis (first of two parts). N Engl J Med 1976, 295:369-377.
    • (1976) N Engl J Med , vol.295 , pp. 369-377
    • Ross, R.1    Glomset, J.A.2
  • 8
    • 0022591979 scopus 로고
    • The pathogenesis of atherosclerosis-an update
    • Ross R. The pathogenesis of atherosclerosis-an update. N Engl J Med 1986, 314:488-500.
    • (1986) N Engl J Med , vol.314 , pp. 488-500
    • Ross, R.1
  • 9
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: a perspective for the 1990s
    • Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 1993, 362:801-809.
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 10
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999, 340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 11
    • 0029299438 scopus 로고
    • The response-to-retention hypothesis of early atherogenesis
    • Williams K.J., Tabas I. The response-to-retention hypothesis of early atherogenesis. Arterioscler Thromb Vasc Biol 1995, 15:551-561.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 551-561
    • Williams, K.J.1    Tabas, I.2
  • 12
    • 0037071843 scopus 로고    scopus 로고
    • Subendothelial retention of atherogenic lipoproteins in early atherosclerosis
    • Skalen K., Gustafsson M., Rydberg E.K., et al. Subendothelial retention of atherogenic lipoproteins in early atherosclerosis. Nature 2002, 417:750-754.
    • (2002) Nature , vol.417 , pp. 750-754
    • Skalen, K.1    Gustafsson, M.2    Rydberg, E.K.3
  • 13
    • 37349021003 scopus 로고    scopus 로고
    • Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications
    • Tabas I., Williams K.J., Boren J. Subendothelial lipoprotein retention as the initiating process in atherosclerosis: update and therapeutic implications. Circulation 2007, 116:1832-1844.
    • (2007) Circulation , vol.116 , pp. 1832-1844
    • Tabas, I.1    Williams, K.J.2    Boren, J.3
  • 15
    • 0031667721 scopus 로고    scopus 로고
    • Risk factors and progression of atherosclerosis in youth. PDAY Research Group. Pathological Determinants of Atherosclerosis in Youth
    • Wissler R.W., Strong J.P. Risk factors and progression of atherosclerosis in youth. PDAY Research Group. Pathological Determinants of Atherosclerosis in Youth. Am J Pathol 1998, 153:1023-1033.
    • (1998) Am J Pathol , vol.153 , pp. 1023-1033
    • Wissler, R.W.1    Strong, J.P.2
  • 16
    • 0033599278 scopus 로고    scopus 로고
    • Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study
    • Strong J.P., Malcom G.T., McMahan C.A., et al. Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study. JAMA 1999, 281:727-735.
    • (1999) JAMA , vol.281 , pp. 727-735
    • Strong, J.P.1    Malcom, G.T.2    McMahan, C.A.3
  • 17
    • 79951669207 scopus 로고    scopus 로고
    • The immune system in atherosclerosis
    • Hansson G.K., Hermansson A. The immune system in atherosclerosis. Nat Immunol 2011, 12:204-212.
    • (2011) Nat Immunol , vol.12 , pp. 204-212
    • Hansson, G.K.1    Hermansson, A.2
  • 18
    • 79955535643 scopus 로고    scopus 로고
    • Macrophages in the pathogenesis of atherosclerosis
    • Moore K.J., Tabas I. Macrophages in the pathogenesis of atherosclerosis. Cell 2011, 145:341-355.
    • (2011) Cell , vol.145 , pp. 341-355
    • Moore, K.J.1    Tabas, I.2
  • 19
    • 81255188900 scopus 로고    scopus 로고
    • Atherosclerosis: current pathogenesis and therapeutic options
    • Weber C., Noels H. Atherosclerosis: current pathogenesis and therapeutic options. Nat Med 2011, 17:1410-1422.
    • (2011) Nat Med , vol.17 , pp. 1410-1422
    • Weber, C.1    Noels, H.2
  • 20
    • 0028350177 scopus 로고
    • The adventitia and atherogenesis: removal initiates intimal proliferation in the rabbit which regresses on generation of a 'neoadventitia'
    • Barker S.G., Tilling L.C., Miller G.C., et al. The adventitia and atherogenesis: removal initiates intimal proliferation in the rabbit which regresses on generation of a 'neoadventitia'. Atherosclerosis 1994, 105:131-144.
    • (1994) Atherosclerosis , vol.105 , pp. 131-144
    • Barker, S.G.1    Tilling, L.C.2    Miller, G.C.3
  • 21
    • 0030065688 scopus 로고    scopus 로고
    • Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content
    • O'Brien K.D., McDonald T.O., Chait A., Allen M.D., Alpers C.E. Neovascular expression of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in human atherosclerosis and their relation to intimal leukocyte content. Circulation 1996, 93:672-682.
    • (1996) Circulation , vol.93 , pp. 672-682
    • O'Brien, K.D.1    McDonald, T.O.2    Chait, A.3    Allen, M.D.4    Alpers, C.E.5
  • 22
    • 33644863344 scopus 로고    scopus 로고
    • Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis
    • de Nooijer R., Verkleij C.J., von der Thusen J.H., et al. Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis. Arterioscler Thromb Vasc Biol 2006, 26:340-346.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 340-346
    • de Nooijer, R.1    Verkleij, C.J.2    von der Thusen, J.H.3
  • 23
    • 0242582259 scopus 로고    scopus 로고
    • Beta-catenin inversely regulates vascular endothelial growth factor-D mRNA stability
    • Orlandini M., Semboloni S., Oliviero S. Beta-catenin inversely regulates vascular endothelial growth factor-D mRNA stability. J Biol Chem 2003, 278:44650-44656.
    • (2003) J Biol Chem , vol.278 , pp. 44650-44656
    • Orlandini, M.1    Semboloni, S.2    Oliviero, S.3
  • 24
    • 70350374339 scopus 로고    scopus 로고
    • Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat diet
    • Pejnovic N., Vratimos A., Lee S.H., et al. Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat diet. Mol Immunol 2009, 47:37-45.
    • (2009) Mol Immunol , vol.47 , pp. 37-45
    • Pejnovic, N.1    Vratimos, A.2    Lee, S.H.3
  • 25
    • 64549126102 scopus 로고    scopus 로고
    • Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells
    • Eid R.E., Rao D.A., Zhou J., et al. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation 2009, 119:1424-1432.
    • (2009) Circulation , vol.119 , pp. 1424-1432
    • Eid, R.E.1    Rao, D.A.2    Zhou, J.3
  • 26
    • 80052277906 scopus 로고    scopus 로고
    • Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1
    • Dang E.V., Barbi J., Yang H.Y., et al. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell 2011, 146:772-784.
    • (2011) Cell , vol.146 , pp. 772-784
    • Dang, E.V.1    Barbi, J.2    Yang, H.Y.3
  • 27
    • 40849086607 scopus 로고    scopus 로고
    • Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis
    • Sluimer J.C., Gasc J.M., van Wanroij J.L., et al. Hypoxia, hypoxia-inducible transcription factor, and macrophages in human atherosclerotic plaques are correlated with intraplaque angiogenesis. J Am Coll Cardiol 2008, 51:1258-1265.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 1258-1265
    • Sluimer, J.C.1    Gasc, J.M.2    van Wanroij, J.L.3
  • 28
    • 80255131449 scopus 로고    scopus 로고
    • Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism
    • Parathath S., Mick S.L., Feig J.E., et al. Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism. Circ Res 2011, 109:1141-1152.
    • (2011) Circ Res , vol.109 , pp. 1141-1152
    • Parathath, S.1    Mick, S.L.2    Feig, J.E.3
  • 29
    • 79952104239 scopus 로고    scopus 로고
    • Macrophages exposed to hypoxia secrete proteoglycans for which LDL has higher affinity
    • Asplund A., Friden V., Stillemark-Billton P., Camejo G., Bondjers G. Macrophages exposed to hypoxia secrete proteoglycans for which LDL has higher affinity. Atherosclerosis 2011, 215:77-81.
    • (2011) Atherosclerosis , vol.215 , pp. 77-81
    • Asplund, A.1    Friden, V.2    Stillemark-Billton, P.3    Camejo, G.4    Bondjers, G.5
  • 30
    • 23744461969 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha polymorphism and coronary collaterals in patients with ischemic heart disease
    • Resar J.R., Roguin A., Voner J., et al. Hypoxia-inducible factor 1alpha polymorphism and coronary collaterals in patients with ischemic heart disease. Chest 2005, 128:787-791.
    • (2005) Chest , vol.128 , pp. 787-791
    • Resar, J.R.1    Roguin, A.2    Voner, J.3
  • 31
    • 33748469407 scopus 로고    scopus 로고
    • Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis
    • Jongstra-Bilen J., Haidari M., Zhu S.N., et al. Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis. J Exp Med 2006, 203:2073-2083.
    • (2006) J Exp Med , vol.203 , pp. 2073-2083
    • Jongstra-Bilen, J.1    Haidari, M.2    Zhu, S.N.3
  • 32
    • 76349096459 scopus 로고    scopus 로고
    • Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis
    • Paulson K.E., Zhu S.N., Chen M., et al. Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis. Circ Res 2010, 106:383-390.
    • (2010) Circ Res , vol.106 , pp. 383-390
    • Paulson, K.E.1    Zhu, S.N.2    Chen, M.3
  • 33
    • 5644273775 scopus 로고    scopus 로고
    • Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization
    • Angeli V., Llodra J., Rong J.X., et al. Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization. Immunity 2004, 21:561-574.
    • (2004) Immunity , vol.21 , pp. 561-574
    • Angeli, V.1    Llodra, J.2    Rong, J.X.3
  • 34
    • 79955601433 scopus 로고    scopus 로고
    • The emerging role of innate immunity in the heart and vascular system
    • Mann D.L. The emerging role of innate immunity in the heart and vascular system. Circ Res 2011, 108:1133-1145.
    • (2011) Circ Res , vol.108 , pp. 1133-1145
    • Mann, D.L.1
  • 35
    • 21944444926 scopus 로고    scopus 로고
    • Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction
    • Holloway J.W., Yang I.A., Ye S. Variation in the toll-like receptor 4 gene and susceptibility to myocardial infarction. Pharmacogenet Genomics 2005, 15:15-21.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 15-21
    • Holloway, J.W.1    Yang, I.A.2    Ye, S.3
  • 36
    • 3242728901 scopus 로고    scopus 로고
    • Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways
    • Bjorkbacka H., Kunjathoor V.V., Moore K.J., et al. Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. Nat Med 2004, 10:416-421.
    • (2004) Nat Med , vol.10 , pp. 416-421
    • Bjorkbacka, H.1    Kunjathoor, V.V.2    Moore, K.J.3
  • 37
    • 21544452747 scopus 로고    scopus 로고
    • Statins decrease toll-like receptor 4 expression and downstream signaling in human CD14+ monocytes
    • Methe H., Kim J.O., Kofler S., Nabauer M., Weis M. Statins decrease toll-like receptor 4 expression and downstream signaling in human CD14+ monocytes. Arterioscler Thromb Vasc Biol 2005, 25:1439-1445.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1439-1445
    • Methe, H.1    Kim, J.O.2    Kofler, S.3    Nabauer, M.4    Weis, M.5
  • 38
    • 18244373708 scopus 로고    scopus 로고
    • Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target
    • Zalewski A., Macphee C. Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target. Arterioscler Thromb Vasc Biol 2005, 25:923-931.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 923-931
    • Zalewski, A.1    Macphee, C.2
  • 39
    • 0033820861 scopus 로고    scopus 로고
    • Low density lipoprotein oxidation, antioxidants, and atherosclerosis
    • Catapano A.L., Maggi F.M., Tragni E. Low density lipoprotein oxidation, antioxidants, and atherosclerosis. Curr Opin Cardiol 2000, 15:355-363.
    • (2000) Curr Opin Cardiol , vol.15 , pp. 355-363
    • Catapano, A.L.1    Maggi, F.M.2    Tragni, E.3
  • 40
    • 77950418219 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 as a novel risk marker for cardiovascular disease: a systematic review of the literature
    • Madjid M., Ali M., Willerson J.T. Lipoprotein-associated phospholipase A2 as a novel risk marker for cardiovascular disease: a systematic review of the literature. Tex Heart Inst J 2010, 37:25-39.
    • (2010) Tex Heart Inst J , vol.37 , pp. 25-39
    • Madjid, M.1    Ali, M.2    Willerson, J.T.3
  • 41
    • 77951605907 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies
    • Thompson A., Gao P., Orfei L., et al. Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet 2010, 375:1536-1544.
    • (2010) Lancet , vol.375 , pp. 1536-1544
    • Thompson, A.1    Gao, P.2    Orfei, L.3
  • 42
    • 0034687446 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group
    • Packard C.J., O'Reilly D.S., Caslake M.J., et al. Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group. N Engl J Med 2000, 343:1148-1155.
    • (2000) N Engl J Med , vol.343 , pp. 1148-1155
    • Packard, C.J.1    O'Reilly, D.S.2    Caslake, M.J.3
  • 43
    • 39549091690 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo Study
    • Daniels L.B., Laughlin G.A., Sarno M.J., et al. Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo Study. J Am Coll Cardiol 2008, 51:913-919.
    • (2008) J Am Coll Cardiol , vol.51 , pp. 913-919
    • Daniels, L.B.1    Laughlin, G.A.2    Sarno, M.J.3
  • 44
    • 58549103715 scopus 로고    scopus 로고
    • Future role for selective phospholipase A2 inhibitors in the prevention of atherosclerotic cardiovascular disease
    • Rosenson R.S. Future role for selective phospholipase A2 inhibitors in the prevention of atherosclerotic cardiovascular disease. Cardiovasc Drugs Ther 2009, 23:93-101.
    • (2009) Cardiovasc Drugs Ther , vol.23 , pp. 93-101
    • Rosenson, R.S.1
  • 45
    • 79955604190 scopus 로고    scopus 로고
    • Anti-inflammatory therapeutics for the treatment of atherosclerosis
    • Charo I.F., Taub R. Anti-inflammatory therapeutics for the treatment of atherosclerosis. Nat Rev Drug Discov 2011, 10:365-376.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 365-376
    • Charo, I.F.1    Taub, R.2
  • 46
    • 53549093853 scopus 로고    scopus 로고
    • Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
    • Wilensky R.L., Shi Y., Mohler E.R., et al. Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development. Nat Med 2008, 14:1059-1066.
    • (2008) Nat Med , vol.14 , pp. 1059-1066
    • Wilensky, R.L.1    Shi, Y.2    Mohler, E.R.3
  • 47
    • 77956663452 scopus 로고    scopus 로고
    • Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation
    • Abela G.S. Cholesterol crystals piercing the arterial plaque and intima trigger local and systemic inflammation. J Clin Lipidol 2010, 4:156-164.
    • (2010) J Clin Lipidol , vol.4 , pp. 156-164
    • Abela, G.S.1
  • 48
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol 1994, 12:991-1045.
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 49
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: a renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science 2002, 296:301-305.
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 50
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: a double-edged sword
    • Hansson G.K., Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol 2006, 6:508-519.
    • (2006) Nat Rev Immunol , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 52
    • 0025800329 scopus 로고
    • Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells
    • Amento E.P., Ehsani N., Palmer H., Libby P. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb 1991, 11:1223-1230.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1223-1230
    • Amento, E.P.1    Ehsani, N.2    Palmer, H.3    Libby, P.4
  • 53
    • 0024811224 scopus 로고
    • Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells
    • Hansson G.K., Hellstrand M., Rymo L., Rubbia L., Gabbiani G. Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells. J Exp Med 1989, 170:1595-1608.
    • (1989) J Exp Med , vol.170 , pp. 1595-1608
    • Hansson, G.K.1    Hellstrand, M.2    Rymo, L.3    Rubbia, L.4    Gabbiani, G.5
  • 54
    • 0028063408 scopus 로고
    • Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
    • Galis Z.S., Sukhova G.K., Lark M.W., Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994, 94:2493-2503.
    • (1994) J Clin Invest , vol.94 , pp. 2493-2503
    • Galis, Z.S.1    Sukhova, G.K.2    Lark, M.W.3    Libby, P.4
  • 55
    • 15844393942 scopus 로고    scopus 로고
    • Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme
    • Yamin T.T., Ayala J.M., Miller D.K. Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme. J Biol Chem 1996, 271:13273-13282.
    • (1996) J Biol Chem , vol.271 , pp. 13273-13282
    • Yamin, T.T.1    Ayala, J.M.2    Miller, D.K.3
  • 56
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon F., Burns K., Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002, 10:417-426.
    • (2002) Mol Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 57
    • 37549002511 scopus 로고    scopus 로고
    • The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
    • Shao W., Yeretssian G., Doiron K., Hussain S.N., Saleh M. The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J Biol Chem 2007, 282:36321-36329.
    • (2007) J Biol Chem , vol.282 , pp. 36321-36329
    • Shao, W.1    Yeretssian, G.2    Doiron, K.3    Hussain, S.N.4    Saleh, M.5
  • 58
    • 33748598700 scopus 로고    scopus 로고
    • Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival
    • Gurcel L., Abrami L., Girardin S., Tschopp J., van der Goot F.G. Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 2006, 126:1135-1145.
    • (2006) Cell , vol.126 , pp. 1135-1145
    • Gurcel, L.1    Abrami, L.2    Girardin, S.3    Tschopp, J.4    van der Goot, F.G.5
  • 59
    • 39749084641 scopus 로고    scopus 로고
    • Active caspase-1 is a regulator of unconventional protein secretion
    • Keller M., Ruegg A., Werner S., Beer H.D. Active caspase-1 is a regulator of unconventional protein secretion. Cell 2008, 132:818-831.
    • (2008) Cell , vol.132 , pp. 818-831
    • Keller, M.1    Ruegg, A.2    Werner, S.3    Beer, H.D.4
  • 60
    • 67650720510 scopus 로고    scopus 로고
    • Immune and inflammatory mechanisms of atherosclerosis
    • Galkina E., Ley K. Immune and inflammatory mechanisms of atherosclerosis Annu Rev Immunol 2009, 27:165-197.
    • (2009) Annu Rev Immunol , vol.27 , pp. 165-197
    • Galkina, E.1    Ley, K.2
  • 61
    • 84858701880 scopus 로고    scopus 로고
    • Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice
    • Shemesh S., Kamari Y., Shaish A., et al. Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice. Atherosclerosis 2012, 222:329-336.
    • (2012) Atherosclerosis , vol.222 , pp. 329-336
    • Shemesh, S.1    Kamari, Y.2    Shaish, A.3
  • 62
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello C.A. Biologic basis for interleukin-1 in disease. Blood 1996, 87:2095-2147.
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 63
    • 84855417535 scopus 로고    scopus 로고
    • Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice
    • Alexander M.R., Moehle C.W., Johnson J.L., et al. Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice. J Clin Invest 2012, 122:70-79.
    • (2012) J Clin Invest , vol.122 , pp. 70-79
    • Alexander, M.R.1    Moehle, C.W.2    Johnson, J.L.3
  • 64
    • 80053644777 scopus 로고    scopus 로고
    • Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)
    • Ridker P.M., Thuren T., Zalewski A., Libby P. Interleukin-1beta inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS). Am Heart J 2011, 162:597-605.
    • (2011) Am Heart J , vol.162 , pp. 597-605
    • Ridker, P.M.1    Thuren, T.2    Zalewski, A.3    Libby, P.4
  • 66
    • 77951800951 scopus 로고    scopus 로고
    • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
    • Duewell P., Kono H., Rayner K.J., et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 2010, 464:1357-1361.
    • (2010) Nature , vol.464 , pp. 1357-1361
    • Duewell, P.1    Kono, H.2    Rayner, K.J.3
  • 67
    • 77955356552 scopus 로고    scopus 로고
    • Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation
    • Rajamaki K., Lappalainen J., Oorni K., et al. Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. PLoS One 2010, 5:e11765.
    • (2010) PLoS One , vol.5
    • Rajamaki, K.1    Lappalainen, J.2    Oorni, K.3
  • 68
    • 79956278851 scopus 로고    scopus 로고
    • Effect of statins on cholesterol crystallization and atherosclerotic plaque stabilization
    • Abela G.S., Vedre A., Janoudi A., et al. Effect of statins on cholesterol crystallization and atherosclerotic plaque stabilization. Am J Cardiol 2011, 107:1710-1717.
    • (2011) Am J Cardiol , vol.107 , pp. 1710-1717
    • Abela, G.S.1    Vedre, A.2    Janoudi, A.3
  • 70
    • 79960015053 scopus 로고    scopus 로고
    • Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE
    • Symmons D.P., Gabriel S.E. Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE. Nat Rev Rheumatol 2011, 7:399-408.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 399-408
    • Symmons, D.P.1    Gabriel, S.E.2
  • 71
    • 32944466887 scopus 로고    scopus 로고
    • Ecological and evolutionary forces shaping microbial diversity in the human intestine
    • Ley R.E., Peterson D.A., Gordon J.I. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell 2006, 124:837-848.
    • (2006) Cell , vol.124 , pp. 837-848
    • Ley, R.E.1    Peterson, D.A.2    Gordon, J.I.3
  • 72
    • 79960365932 scopus 로고    scopus 로고
    • Lipid metabolism by gut microbes and atherosclerosis
    • Loscalzo J. Lipid metabolism by gut microbes and atherosclerosis. Circ Res 2011, 109:127-129.
    • (2011) Circ Res , vol.109 , pp. 127-129
    • Loscalzo, J.1
  • 73
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J., Li R., Raes J., et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010, 464:59-65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 74
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh P.J., Ley R.E., Mahowald M.A., et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 2006, 444:1027-1031.
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3
  • 75
    • 33747618036 scopus 로고    scopus 로고
    • Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice
    • Dumas M.E., Barton R.H., Toye A., et al. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc Natl Acad Sci U S A 2006, 103:12511-12516.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 12511-12516
    • Dumas, M.E.1    Barton, R.H.2    Toye, A.3
  • 76
    • 79953733693 scopus 로고    scopus 로고
    • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
    • Wang Z., Klipfell E., Bennett B.J., et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 2011, 472:57-63.
    • (2011) Nature , vol.472 , pp. 57-63
    • Wang, Z.1    Klipfell, E.2    Bennett, B.J.3
  • 77
    • 38349078772 scopus 로고    scopus 로고
    • Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model
    • Martin F.P., Wang Y., Sprenger N., et al. Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model. Mol Syst Biol 2008, 4:157.
    • (2008) Mol Syst Biol , vol.4 , pp. 157
    • Martin, F.P.1    Wang, Y.2    Sprenger, N.3
  • 78
    • 77956310020 scopus 로고    scopus 로고
    • Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism
    • Caesar R., Fak F., Backhed F. Effects of gut microbiota on obesity and atherosclerosis via modulation of inflammation and lipid metabolism. J Intern Med 2010, 268:320-328.
    • (2010) J Intern Med , vol.268 , pp. 320-328
    • Caesar, R.1    Fak, F.2    Backhed, F.3
  • 79
    • 79952384278 scopus 로고    scopus 로고
    • The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases
    • Tlaskalova-Hogenova H., Stepankova R., Kozakova H., et al. The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases. Cell Mol Immunol 2011, 8:110-120.
    • (2011) Cell Mol Immunol , vol.8 , pp. 110-120
    • Tlaskalova-Hogenova, H.1    Stepankova, R.2    Kozakova, H.3
  • 80
    • 77950250064 scopus 로고    scopus 로고
    • Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
    • Vijay-Kumar M., Aitken J.D., Carvalho F.A., et al. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science 2010, 328:228-231.
    • (2010) Science , vol.328 , pp. 228-231
    • Vijay-Kumar, M.1    Aitken, J.D.2    Carvalho, F.A.3
  • 81
    • 0037159293 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis
    • Hurlimann D., Forster A., Noll G., et al. Anti-tumor necrosis factor-alpha treatment improves endothelial function in patients with rheumatoid arthritis. Circulation 2002, 106:2184-2187.
    • (2002) Circulation , vol.106 , pp. 2184-2187
    • Hurlimann, D.1    Forster, A.2    Noll, G.3
  • 82
    • 69249222895 scopus 로고    scopus 로고
    • Role for TNF in atherosclerosis?. Lessons from autoimmune disease
    • McKellar G.E., McCarey D.W., Sattar N., McInnes I.B. Role for TNF in atherosclerosis?. Lessons from autoimmune disease. Nat Rev Cardiol 2009, 6:410-417.
    • (2009) Nat Rev Cardiol , vol.6 , pp. 410-417
    • McKellar, G.E.1    McCarey, D.W.2    Sattar, N.3    McInnes, I.B.4
  • 83
    • 33744792493 scopus 로고    scopus 로고
    • Short-term adalimumab therapy improves endo-thelial function in patients with rheumatoid arthritis refractory to infliximab
    • Gonzalez-Juanatey C., Llorca J., Sanchez-Andrade A., et al. Short-term adalimumab therapy improves endo-thelial function in patients with rheumatoid arthritis refractory to infliximab. Clin Exp Rheumatol 2006, 24:309-312.
    • (2006) Clin Exp Rheumatol , vol.24 , pp. 309-312
    • Gonzalez-Juanatey, C.1    Llorca, J.2    Sanchez-Andrade, A.3
  • 84
    • 78349245587 scopus 로고    scopus 로고
    • Accelerated atherosclerosis in systemic lupus erythematosus: role of proinflammatory cytokines and therapeutic approaches
    • pii 607084
    • Lopez-Pedrera C., Aguirre M.A., Barbarroja N., Cuadrado M.J. Accelerated atherosclerosis in systemic lupus erythematosus: role of proinflammatory cytokines and therapeutic approaches. J Biomed Biotechnol 2010, 2010. pii 607084.
    • (2010) J Biomed Biotechnol , vol.2010
    • Lopez-Pedrera, C.1    Aguirre, M.A.2    Barbarroja, N.3    Cuadrado, M.J.4
  • 85
    • 33745847843 scopus 로고    scopus 로고
    • Drug insight: immunomodulatory effects of statins-potential benefits for renal patients?
    • Steffens S., Mach F. Drug insight: immunomodulatory effects of statins-potential benefits for renal patients?. Nat Clin Pract Neph 2006, 2:378-387.
    • (2006) Nat Clin Pract Neph , vol.2 , pp. 378-387
    • Steffens, S.1    Mach, F.2
  • 86
    • 71549121695 scopus 로고    scopus 로고
    • Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies
    • Klingenberg R., Hansson G.K. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. Eur Heart J 2009, 30:2838-2844.
    • (2009) Eur Heart J , vol.30 , pp. 2838-2844
    • Klingenberg, R.1    Hansson, G.K.2
  • 87
    • 11344279659 scopus 로고    scopus 로고
    • C-reactive protein levels and outcomes after statin therapy
    • Ridker P.M., Cannon C.P., Morrow D., et al. C-reactive protein levels and outcomes after statin therapy. N Engl J Med 2005, 352:20-28.
    • (2005) N Engl J Med , vol.352 , pp. 20-28
    • Ridker, P.M.1    Cannon, C.P.2    Morrow, D.3
  • 88
    • 33748064338 scopus 로고    scopus 로고
    • Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial
    • Morrow D.A., de Lemos J.A., Sabatine M.S., et al. Clinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor Trial. Circulation 2006, 114:281-288.
    • (2006) Circulation , vol.114 , pp. 281-288
    • Morrow, D.A.1    de Lemos, J.A.2    Sabatine, M.S.3
  • 89
    • 19944429519 scopus 로고    scopus 로고
    • Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease
    • Nissen S.E., Tuzcu E.M., Schoenhagen P., et al. Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease. N Engl J Med 2005, 352:29-38.
    • (2005) N Engl J Med , vol.352 , pp. 29-38
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3
  • 90
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • Ridker P.M., Danielson E., Fonseca F.A., et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008, 359:2195-2207.
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 91
    • 80053914425 scopus 로고    scopus 로고
    • Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists
    • Davidson M.H., Ballantyne C.M., Jacobson T.A., et al. Clinical utility of inflammatory markers and advanced lipoprotein testing: advice from an expert panel of lipid specialists. J Clin Lipidol 2011, 5:338-367.
    • (2011) J Clin Lipidol , vol.5 , pp. 338-367
    • Davidson, M.H.1    Ballantyne, C.M.2    Jacobson, T.A.3
  • 92
    • 0035099170 scopus 로고    scopus 로고
    • Generation of C-reactive protein and complement components in atherosclerotic plaques
    • Yasojima K., Schwab C., McGeer E.G., McGeer P.L. Generation of C-reactive protein and complement components in atherosclerotic plaques. Am J Pathol 2001, 158:1039-1051.
    • (2001) Am J Pathol , vol.158 , pp. 1039-1051
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 93
    • 0037469177 scopus 로고    scopus 로고
    • Clinical application of C-reactive protein for cardiovascular disease detection and prevention
    • Ridker P.M. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation 2003, 107:363-369.
    • (2003) Circulation , vol.107 , pp. 363-369
    • Ridker, P.M.1
  • 94
    • 0034739462 scopus 로고    scopus 로고
    • Direct proinflammatory effect of C-reactive protein on human endothelial cells
    • Pasceri V., Willerson J.T., Yeh E.T. Direct proinflammatory effect of C-reactive protein on human endothelial cells. Circulation 2000, 102:2165-2168.
    • (2000) Circulation , vol.102 , pp. 2165-2168
    • Pasceri, V.1    Willerson, J.T.2    Yeh, E.T.3
  • 95
    • 84872501468 scopus 로고    scopus 로고
    • Human C-reactive protein accentuates macrophage activity in biobreeding diabetic rats
    • [Epub ahead of print]
    • Jialal I., Kaur H., Devaraj S. Human C-reactive protein accentuates macrophage activity in biobreeding diabetic rats. J Diabetes Complications 2012, [Epub ahead of print].
    • (2012) J Diabetes Complications
    • Jialal, I.1    Kaur, H.2    Devaraj, S.3
  • 96
    • 84862817321 scopus 로고    scopus 로고
    • C-reactive protein down-regulates endothelial nitric oxide synthase expression and promotes apoptosis in endothelial progenitor cells through receptor for advanced glycation end-products
    • Chen J., Jin J., Song M., et al. C-reactive protein down-regulates endothelial nitric oxide synthase expression and promotes apoptosis in endothelial progenitor cells through receptor for advanced glycation end-products. Gene 2012, 496:128-135.
    • (2012) Gene , vol.496 , pp. 128-135
    • Chen, J.1    Jin, J.2    Song, M.3
  • 97
    • 33748425073 scopus 로고    scopus 로고
    • Insight into the nature of the CRP-coronary event association using Mendelian randomization
    • Casas J.P., Shah T., Cooper J., et al. Insight into the nature of the CRP-coronary event association using Mendelian randomization. Int J Epidemiol 2006, 35:922-931.
    • (2006) Int J Epidemiol , vol.35 , pp. 922-931
    • Casas, J.P.1    Shah, T.2    Cooper, J.3
  • 98
    • 79952975082 scopus 로고    scopus 로고
    • Quantification of coronary atherosclerosis and inflammation to predict coronary events and all-cause mortality
    • Mohlenkamp S., Lehmann N., Moebus S., et al. Quantification of coronary atherosclerosis and inflammation to predict coronary events and all-cause mortality. J Am Coll Cardiol 2011, 57:1455-1464.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 1455-1464
    • Mohlenkamp, S.1    Lehmann, N.2    Moebus, S.3
  • 99
    • 77953904713 scopus 로고    scopus 로고
    • Screening asymptomatic subjects for subclinical atherosclerosis: can we, does it matter, and should we?
    • Shah P.K. Screening asymptomatic subjects for subclinical atherosclerosis: can we, does it matter, and should we?. J Am Coll Cardiol 2010, 56:98-105.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 98-105
    • Shah, P.K.1
  • 100
    • 80052022090 scopus 로고    scopus 로고
    • Why not screen for subclinical atherosclerosis?
    • Sillesen H., Falk E. Why not screen for subclinical atherosclerosis?. Lancet 2011, 378:645-646.
    • (2011) Lancet , vol.378 , pp. 645-646
    • Sillesen, H.1    Falk, E.2
  • 101
    • 33745158352 scopus 로고    scopus 로고
    • Letter by Williams and Tabas regarding article "atherosclerosis 2005: recent discoveries and novel hypotheses"
    • author reply e3
    • Williams K.J., Tabas I. Letter by Williams and Tabas regarding article "atherosclerosis 2005: recent discoveries and novel hypotheses". Circulation 2006, 113:e782. author reply e3.
    • (2006) Circulation , vol.113
    • Williams, K.J.1    Tabas, I.2


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