메뉴 건너뛰기




Volumn 37, Issue 1, 2010, Pages 25-39

Lipoprotein-associated phospholipase A2 as a novel risk marker for cardiovascular disease: A systematic review of the literature

Author keywords

Atherosclerosis prevention control; Biological markers blood; C reactive protein; Case control studies; Cohort studies; Epidemiology; Inflammation; Lipoprotein associated phospholipase A2; Phospholipases A2; Treatment outcome

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE;

EID: 77950418219     PISSN: 07302347     EISSN: 15266702     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (42)

References (74)
  • 1
    • 0042697063 scopus 로고    scopus 로고
    • Prevalence of conventional risk factors in patients with coronary heart disease
    • Khot UN, Khot MB, Bajzer CT, Sapp SK, Ohman EM, Brener SJ, et al. Prevalence of conventional risk factors in patients with coronary heart disease. JAMA 2003;290(7):898-904.
    • (2003) JAMA , vol.290 , Issue.7 , pp. 898-904
    • Khot, U.N.1    Khot, M.B.2    Bajzer, C.T.3    Sapp, S.K.4    Ohman, E.M.5    Brener, S.J.6
  • 2
    • 0029756177 scopus 로고    scopus 로고
    • Lipids, risk factors and ischaemic heart disease
    • Castelli WP. Lipids, risk factors and ischaemic heart disease. Atherosclerosis 1996;124 Suppl:S1-9.
    • (1996) Atherosclerosis , vol.124 , Issue.SUPPL.
    • Castelli, W.P.1
  • 3
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis- An inflammatory disease
    • Ross R. Atherosclerosis- an inflammatory disease. N Engl J Med 1999;340(2):115-26.
    • (1999) N Engl J Med , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 4
    • 2642535951 scopus 로고    scopus 로고
    • Inflammation as a cardiovascular risk factor
    • Willerson JT, Ridker PM. Inflammation as a cardiovascular risk factor. Circulation 2004;109(21 Suppl 1):II2-10.
    • (2004) Circulation , vol.109 , Issue.21 SUPPL. 1
    • Willerson, J.T.1    Ridker, P.M.2
  • 5
    • 0032566401 scopus 로고    scopus 로고
    • Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women
    • Ridker PM, Buring JE, Shih J, Matias M, Hennekens CH. Prospective study of C-reactive protein and the risk of future cardiovascular events among apparently healthy women. Circulation 1998;98(8):731-3.
    • (1998) Circulation , vol.98 , Issue.8 , pp. 731-733
    • Ridker, P.M.1    Buring, J.E.2    Shih, J.3    Matias, M.4    Hennekens, C.H.5
  • 6
    • 8144223156 scopus 로고    scopus 로고
    • Leukocyte count and coronary heart disease: Implications for risk assessment
    • Madjid M, Awan I, Willerson JT, Casscells SW. Leukocyte count and coronary heart disease: implications for risk assessment. J Am Coll Cardiol 2004;44(10):1945-56.
    • (2004) J Am Coll Cardiol , vol.44 , Issue.10 , pp. 1945-1956
    • Madjid, M.1    Awan, I.2    Willerson, J.T.3    Casscells, S.W.4
  • 7
    • 67049172713 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2: A cardiovascular risk predictor and a potential therapeutic target
    • Ali M, Madjid M. Lipoprotein-associated phospholipase A2: a cardiovascular risk predictor and a potential therapeutic target. Future Cardiol 2009;5(2):159-73.
    • (2009) Future Cardiol , vol.5 , Issue.2 , pp. 159-173
    • Ali, M.1    Madjid, M.2
  • 8
    • 0028968049 scopus 로고
    • Anti-inflammatory properties of a platelet-activating factor acetylhydrolase
    • Tjoelker LW, Wilder C, Eberhardt C, Stafforini DM, Dietsch G, Schimpf B, et al. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase. Nature 1995;374(6522): 549-53.
    • (1995) Nature , vol.374 , Issue.6522 , pp. 549-553
    • Tjoelker, L.W.1    Wilder, C.2    Eberhardt, C.3    Stafforini, D.M.4    Dietsch, G.5    Schimpf, B.6
  • 9
    • 18244373708 scopus 로고    scopus 로고
    • Role of lipoprotein-associated phospholipase A2 in atherosclerosis: Biology, epidemiology, and possible therapeutic target
    • Zalewski A, Macphee C. Role of lipoprotein-associated phospholipase A2 in atherosclerosis: biology, epidemiology, and possible therapeutic target. Arterioscler Thromb Vasc Biol 2005;25(5):923-31.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.5 , pp. 923-931
    • Zalewski, A.1    Macphee, C.2
  • 10
    • 0028236549 scopus 로고
    • Distribution of PAF-acetylhydrolase activity in human plasma low-density lipoprotein subfractions
    • Karabina SA, Liapikos TA, Grekas G, Goudevenos J, Tselepis AD. Distribution of PAF-acetylhydrolase activity in human plasma low-density lipoprotein subfractions. Biochim Biophys Acta 1994;1213(1):34-8.
    • (1994) Biochim Biophys Acta , vol.1213 , Issue.1 , pp. 34-38
    • Karabina, S.A.1    Liapikos, T.A.2    Grekas, G.3    Goudevenos, J.4    Tselepis, A.D.5
  • 11
    • 28044453286 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 activity is a marker of small, dense LDL particles in human plasma
    • Gazi I, Lourida ES, Filippatos T, Tsimihodimos V, Elisaf M, Tselepis AD. Lipoprotein-associated phospholipase A2 activity is a marker of small, dense LDL particles in human plasma. Clin Chem 2005;51(12):2264-73.
    • (2005) Clin Chem , vol.51 , Issue.12 , pp. 2264-2273
    • Gazi, I.1    Lourida, E.S.2    Filippatos, T.3    Tsimihodimos, V.4    Elisaf, M.5    Tselepis, A.D.6
  • 12
    • 0033789652 scopus 로고    scopus 로고
    • Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position
    • Subbanagounder G, Leitinger N, Schwenke DC, Wong JW, Lee H, Rizza C, et al. Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position. Arterioscler Thromb Vasc Biol 2000;20(10):2248-54.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , Issue.10 , pp. 2248-2254
    • Subbanagounder, G.1    Leitinger, N.2    Schwenke, D.C.3    Wong, J.W.4    Lee, H.5    Rizza, C.6
  • 13
    • 0036510551 scopus 로고    scopus 로고
    • Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta
    • Subbanagounder G, Wong JW, Lee H, Faull KF, Miller E, Witztum JL, Berliner JA. Epoxyisoprostane and epoxycyclopentenone phospholipids regulate monocyte chemotactic protein-1 and interleukin-8 synthesis. Formation of these oxidized phospholipids in response to interleukin-1beta. J Biol Chem 2002;277(9):7271-81.
    • (2002) J Biol Chem , vol.277 , Issue.9 , pp. 7271-7281
    • Subbanagounder, G.1    Wong, J.W.2    Lee, H.3    Faull, K.F.4    Miller, E.5    Witztum, J.L.6    Berliner, J.A.7
  • 15
    • 0035901582 scopus 로고    scopus 로고
    • Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes
    • Ehara S, Ueda M, Naruko T, Haze K, Itoh A, Otsuka M, et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 2001;103(15):1955-60.
    • (2001) Circulation , vol.103 , Issue.15 , pp. 1955-1960
    • Ehara, S.1    Ueda, M.2    Naruko, T.3    Haze, K.4    Itoh, A.5    Otsuka, M.6
  • 16
    • 0343852114 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase, is expressed by macrophages in human and rabbit atherosclerotic lesions
    • Hakkinen T, Luoma JS, Hiltunen MO, Macphee CH, Milliner KJ, Patel L, et al. Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase, is expressed by macrophages in human and rabbit atherosclerotic lesions. Arterioscler Thromb Vasc Biol 1999;19(12):2909-17.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , Issue.12 , pp. 2909-2917
    • Hakkinen, T.1    Luoma, J.S.2    Hiltunen, M.O.3    Macphee, C.H.4    Milliner, K.J.5    Patel, L.6
  • 18
    • 0023186806 scopus 로고
    • Membrane phospholipid metabolism during myocardial ischaemia: Past, present and future
    • Sen A, Buja LM, Willerson JT, Chien KR. Membrane phospholipid metabolism during myocardial ischaemia: past, present and future. Basic Res Cardiol 1987;82 Suppl 1:121-5.
    • (1987) Basic Res Cardiol , vol.82 , Issue.SUPPL. 1 , pp. 121-125
    • Sen, A.1    Buja, L.M.2    Willerson, J.T.3    Chien, K.R.4
  • 19
    • 0021977754 scopus 로고
    • Phospholipid alterations and membrane injury during myocardial ischemia
    • Chien KR, Willerson JT, Buja LM. Phospholipid alterations and membrane injury during myocardial ischemia. Adv Myocardiol 1985;5:347-53.
    • (1985) Adv Myocardiol , vol.5 , pp. 347-353
    • Chien, K.R.1    Willerson, J.T.2    Buja, L.M.3
  • 20
    • 0042858243 scopus 로고    scopus 로고
    • Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles
    • Watanabe J, Marathe GK, Neilsen PO, Weyrich AS, Harrison KA, Murphy RC, et al. Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles. J Biol Chem 2003;278(35):33161-8.
    • (2003) J Biol Chem , vol.278 , Issue.35 , pp. 33161-33168
    • Watanabe, J.1    Marathe, G.K.2    Neilsen, P.O.3    Weyrich, A.S.4    Harrison, K.A.5    Murphy, R.C.6
  • 21
    • 0032765305 scopus 로고    scopus 로고
    • In vivo regulation of plasma platelet-activating factor acetylhydrolase during the acute phase response
    • Memon RA, Fuller J, Moser AH, Feingold KR, Grunfeld C. In vivo regulation of plasma platelet-activating factor acetylhydrolase during the acute phase response. Am J Physiol 1999; 277(1 Pt 2):R94-103.
    • (1999) Am J Physiol , vol.277 , Issue.1 PART 2
    • Memon, R.A.1    Fuller, J.2    Moser, A.H.3    Feingold, K.R.4    Grunfeld, C.5
  • 22
    • 18844421079 scopus 로고    scopus 로고
    • Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase
    • Castro Faria Neto HC, Stafforini DM, Prescott SM, Zimmerman GA. Regulating inflammation through the anti-inflammatory enzyme platelet-activating factor-acetylhydrolase. Mem Inst Oswaldo Cruz 2005;100 Suppl 1:83-91.
    • (2005) Mem Inst Oswaldo Cruz , vol.100 , Issue.SUPPL. 1 , pp. 83-91
    • Castro Faria Neto, H.C.1    Stafforini, D.M.2    Prescott, S.M.3    Zimmerman, G.A.4
  • 23
    • 0345633704 scopus 로고    scopus 로고
    • Platelet-activating factor acetylhydrolase prevents myocardial ischemia-reperfusion injury
    • Morgan EN, Boyle EM Jr, Yun W, Kovacich JC, Canty TG Jr, Chi E, et al. Platelet-activating factor acetylhydrolase prevents myocardial ischemia-reperfusion injury. Circulation 1999;100(19 Suppl):II365-8.
    • (1999) Circulation , vol.100
    • Morgan, E.N.1    Boyle Jr., E.M.2    Yun, W.3    Kovacich, J.C.4    Canty Jr., T.G.5    Chi, E.6
  • 25
    • 0028349237 scopus 로고
    • Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells
    • Kume N, Gimbrone MA Jr. Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells. J Clin Invest 1994;93(2):907-11.
    • (1994) J Clin Invest , vol.93 , Issue.2 , pp. 907-911
    • Kume, N.1    Gimbrone Jr., M.A.2
  • 26
    • 0038352228 scopus 로고    scopus 로고
    • Inf lammation, bioactive lipids and atherosclerosis: Potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase
    • Tselepis AD, John Chapman M. Inf lammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase. Atheroscler Suppl 2002;3(4):57-68.
    • (2002) Atheroscler Suppl , vol.3 , Issue.4 , pp. 57-68
    • Tselepis, A.D.1    John Chapman, M.2
  • 28
    • 20144389620 scopus 로고    scopus 로고
    • Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: The EPIC-Norfolk Prospective Population Study
    • Boekholdt SM, Keller TT, Wareham NJ, Luben R, Bingham SA, Day NE, et al. Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study. Arterioscler Thromb Vasc Biol 2005;25(4):839-46.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.4 , pp. 839-846
    • Boekholdt, S.M.1    Keller, T.T.2    Wareham, N.J.3    Luben, R.4    Bingham, S.A.5    Day, N.E.6
  • 29
    • 77950454721 scopus 로고    scopus 로고
    • Critical Appraisal Tools
    • Available at
    • Critical Appraisal Tools. Public Health Resource Unit. Available at: http://www.phru.nhs.uk/Pages/PHD/resources.htm
    • Public Health Resource Unit
  • 30
    • 14144256273 scopus 로고    scopus 로고
    • Association of lipoprotein-associated phospholipase A2 levels with coronary artery disease risk factors, angiographic coronary artery disease, and major adverse events at follow-up
    • Brilakis ES, McConnell JP, Lennon RJ, Elesber AA, Meyer JG, Berger PB. Association of lipoprotein-associated phospholipase A2 levels with coronary artery disease risk factors, angiographic coronary artery disease, and major adverse events at follow-up. Eur Heart J 2005;26(2):137-44.
    • (2005) Eur Heart J , vol.26 , Issue.2 , pp. 137-144
    • Brilakis, E.S.1    McConnell, J.P.2    Lennon, R.J.3    Elesber, A.A.4    Meyer, J.G.5    Berger, P.B.6
  • 31
    • 33646685941 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin Or atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction) trial
    • O'Donoghue M, Morrow DA, Sabatine MS, Murphy SA, McCabe CH, Cannon CP, Braunwald E. Lipoprotein-associated phospholipase A2 and its association with cardiovascular outcomes in patients with acute coronary syndromes in the PROVE IT-TIMI 22 (PRavastatin Or atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction) trial. Circulation 2006;113(14):1745-52.
    • (2006) Circulation , vol.113 , Issue.14 , pp. 1745-1752
    • O'Donoghue, M.1    Morrow, D.A.2    Sabatine, M.S.3    Murphy, S.A.4    McCabe, C.H.5    Cannon, C.P.6    Braunwald, E.7
  • 32
    • 33745965348 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 predicts future cardiovascular events in patients with coronary heart disease independently of traditional risk factors, markers of inflammation, renal function, and hemodynamic stress
    • Koenig W, Twardella D, Brenner H, Rothenbacher D. Lipoprotein-associated phospholipase A2 predicts future cardiovascular events in patients with coronary heart disease independently of traditional risk factors, markers of inflammation, renal function, and hemodynamic stress. Arterioscler Thromb Vasc Biol 2006;26(7):1586-93.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.7 , pp. 1586-1593
    • Koenig, W.1    Twardella, D.2    Brenner, H.3    Rothenbacher, D.4
  • 33
    • 33745475120 scopus 로고    scopus 로고
    • High lipoprotein-associated phospholipase A2 is a risk factor for recurrent coronary events in postinfarction patients
    • Corsetti JP, Rainwater DL, Moss AJ, Zareba W, Sparks CE. High lipoprotein-associated phospholipase A2 is a risk factor for recurrent coronary events in postinfarction patients. Clin Chem 2006;52(7):1331-8.
    • (2006) Clin Chem , vol.52 , Issue.7 , pp. 1331-1338
    • Corsetti, J.P.1    Rainwater, D.L.2    Moss, A.J.3    Zareba, W.4    Sparks, C.E.5
  • 35
    • 33750370865 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 independently predicts the angiographic diagnosis of coronary artery disease and coronary death
    • May HT, Horne BD, Anderson JL, Wolfert RL, Muhlestein JB, Renlund DG, et al. Lipoprotein-associated phospholipase A2 independently predicts the angiographic diagnosis of coronary artery disease and coronary death. Am Heart J 2006;152 (5):997-1003.
    • (2006) Am Heart J , vol.152 , Issue.5 , pp. 997-1003
    • May, H.T.1    Horne, B.D.2    Anderson, J.L.3    Wolfert, R.L.4    Muhlestein, J.B.5    Renlund, D.G.6
  • 37
    • 33750343590 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2, and outcome after ischemic stroke
    • Elkind MS, Tai W, Coates K, Paik MC, Sacco RL. High-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2, and outcome after ischemic stroke. Arch Intern Med 2006;166(19):2073-80.
    • (2006) Arch Intern Med , vol.166 , Issue.19 , pp. 2073-2080
    • Elkind, M.S.1    Tai, W.2    Coates, K.3    Paik, M.C.4    Sacco, R.L.5
  • 38
    • 34249713287 scopus 로고    scopus 로고
    • Elevated Lp-PLA2 levels add prognostic information to the metabolic syndrome on incidence of cardiovascular events among middle-aged nondiabetic subjects
    • Persson M, Hedblad B, Nelson JJ, Berglund G. Elevated Lp-PLA2 levels add prognostic information to the metabolic syndrome on incidence of cardiovascular events among middle-aged nondiabetic subjects. Arterioscler Thromb Vasc Biol 2007;27(6):1411-6.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.6 , pp. 1411-1416
    • Persson, M.1    Hedblad, B.2    Nelson, J.J.3    Berglund, G.4
  • 39
    • 34548609185 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 for early risk stratification in patients with suspected acute coronary syndrome: A multi-marker approach: The North Wuerttemberg and Berlin Infarction Study-II (NOBIS-II)
    • Mockel M, Muller R, Vollert JO, Muller C, Danne O, Gareis R, et al. Lipoprotein-associated phospholipase A2 for early risk stratification in patients with suspected acute coronary syndrome: a multi-marker approach: the North Wuerttemberg and Berlin Infarction Study-II (NOBIS-II). Clin Res Cardiol 2007;96(9):604-12.
    • (2007) Clin Res Cardiol , vol.96 , Issue.9 , pp. 604-612
    • Mockel, M.1    Muller, R.2    Vollert, J.O.3    Muller, C.4    Danne, O.5    Gareis, R.6
  • 40
    • 36048962679 scopus 로고    scopus 로고
    • Prognostic utility of lipoproteinassociated phospholipase A2 for cardiovascular outcomes in patients with stable coronary artery disease
    • Sabatine MS, Morrow DA, O'Donoghue M, Jablonksi KA, Rice MM, Solomon S, et al. Prognostic utility of lipoproteinassociated phospholipase A2 for cardiovascular outcomes in patients with stable coronary artery disease. Arterioscler Thromb Vasc Biol 2007;27(11):2463-9.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.11 , pp. 2463-2469
    • Sabatine, M.S.1    Morrow, D.A.2    O'Donoghue, M.3    Jablonksi, K.A.4    Rice, M.M.5    Solomon, S.6
  • 41
    • 34547614814 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 predicts 5-year cardiac mortality independently of established risk factors and adds prognostic information in patients with low and medium high-sensitivity C-reactive protein (the Ludwigshafen risk and cardiovascular health study)
    • Winkler K, Hoffmann MM, Winkelmann BR, Friedrich I, Schafer G, Seelhorst U, et al. Lipoprotein-associated phospholipase A2 predicts 5-year cardiac mortality independently of established risk factors and adds prognostic information in patients with low and medium high-sensitivity C-reactive protein (the Ludwigshafen risk and cardiovascular health study). Clin Chem 2007;53(8):1440-7.
    • (2007) Clin Chem , vol.53 , Issue.8 , pp. 1440-1447
    • Winkler, K.1    Hoffmann, M.M.2    Winkelmann, B.R.3    Friedrich, I.4    Schafer, G.5    Seelhorst, U.6
  • 42
    • 34547627109 scopus 로고    scopus 로고
    • Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: Prospective results from the Bruneck study
    • Kiechl S, Willeit J, Mayr M, Viehweider B, Oberhollenzer M, Kronenberg F, et al. Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study. Arterioscler Thromb Vasc Biol 2007;27(8):1788-95.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.8 , pp. 1788-1795
    • Kiechl, S.1    Willeit, J.2    Mayr, M.3    Viehweider, B.4    Oberhollenzer, M.5    Kronenberg, F.6
  • 43
    • 77950456536 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 and high sensitivity C-reactive protein levels and the prediction of cardiovascular risk among coronary artery disease patients with differing clinical patients
    • [abstract]
    • May HT, Anderson JL, Horne BD, Pearson RR, Wolfert RL, Kolek MJ, et al. Lipoprotein-associated phospholipase A2 and high sensitivity C-reactive protein levels and the prediction of cardiovascular risk among coronary artery disease patients with differing clinical patients [abstract]. Circulation 2007;116:II 799-800.
    • (2007) Circulation , vol.116 , Issue.II , pp. 799-800
    • May, H.T.1    Anderson, J.L.2    Horne, B.D.3    Pearson, R.R.4    Wolfert, R.L.5    Kolek, M.J.6
  • 44
    • 39549091690 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: The Rancho Bernardo Study
    • Daniels LB, Laughlin GA, Sarno MJ, Bettencourt R, Wolfert RL, Barrett-Connor E. Lipoprotein-associated phospholipase A2 is an independent predictor of incident coronary heart disease in an apparently healthy older population: the Rancho Bernardo Study. J Am Coll Cardiol 2008;51(9):913-9.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.9 , pp. 913-919
    • Daniels, L.B.1    Laughlin, G.A.2    Sarno, M.J.3    Bettencourt, R.4    Wolfert, R.L.5    Barrett-Connor, E.6
  • 45
    • 42149109624 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 predicts progression of cardiac allograft vasculopathy and increased risk of cardiovascular events in heart transplant patients
    • Raichlin E, McConnell JP, Bae JH, Kremers WK, Lerman A, Frantz RP. Lipoprotein-associated phospholipase A2 predicts progression of cardiac allograft vasculopathy and increased risk of cardiovascular events in heart transplant patients. Transplantation 2008;85(7):963-8.
    • (2008) Transplantation , vol.85 , Issue.7 , pp. 963-968
    • Raichlin, E.1    McConnell, J.P.2    Bae, J.H.3    Kremers, W.K.4    Lerman, A.5    Frantz, R.P.6
  • 47
    • 58149157445 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: Results from the Bruneck study
    • Tsimikas S, Willeit J, Knoflach M, Mayr M, Egger G, Notdurfter M, et al. Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study. Eur Heart J 2009;30(1):107-15.
    • (2009) Eur Heart J , vol.30 , Issue.1 , pp. 107-115
    • Tsimikas, S.1    Willeit, J.2    Knoflach, M.3    Mayr, M.4    Egger, G.5    Notdurfter, M.6
  • 48
    • 0034687446 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group
    • Packard CJ, O'Reilly DS, Caslake MJ, McMahon AD, Ford I, Cooney J, et al. Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group. N Engl J Med 2000;343(16):1148-55.
    • (2000) N Engl J Med , vol.343 , Issue.16 , pp. 1148-1155
    • Packard, C.J.1    O'Reilly, D.S.2    Caslake, M.J.3    McMahon, A.D.4    Ford, I.5    Cooney, J.6
  • 49
    • 0035498968 scopus 로고    scopus 로고
    • A prospective evaluation of lipoprotein-associated phospholipase A(2) levels and the risk of future cardiovascular events in women
    • Blake GJ, Dada N, Fox JC, Manson JE, Ridker PM. A prospective evaluation of lipoprotein-associated phospholipase A(2) levels and the risk of future cardiovascular events in women. J Am Coll Cardiol 2001;38(5):1302-6.
    • (2001) J Am Coll Cardiol , vol.38 , Issue.5 , pp. 1302-1306
    • Blake, G.J.1    Dada, N.2    Fox, J.C.3    Manson, J.E.4    Ridker, P.M.5
  • 50
    • 4944261232 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 adds to risk prediction of incident coronary events by C-reactive protein in apparently healthy middle-aged men from the general population: Results from the 14-year follow-up of a large cohort from southern Germany
    • Koenig W, Khuseyinova N, Lowel H, Trischler G, Meisinger C. Lipoprotein-associated phospholipase A2 adds to risk prediction of incident coronary events by C-reactive protein in apparently healthy middle-aged men from the general population: results from the 14-year follow-up of a large cohort from southern Germany. Circulation 2004;110(14):1903-8.
    • (2004) Circulation , vol.110 , Issue.14 , pp. 1903-1908
    • Koenig, W.1    Khuseyinova, N.2    Lowel, H.3    Trischler, G.4    Meisinger, C.5
  • 51
    • 1342331006 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study
    • Ballantyne CM, Hoogeveen RC, Bang H, Coresh J, Folsom AR, Heiss G, Sharrett AR. Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study. Circulation 2004;109(7):837-42.
    • (2004) Circulation , vol.109 , Issue.7 , pp. 837-842
    • Ballantyne, C.M.1    Hoogeveen, R.C.2    Bang, H.3    Coresh, J.4    Folsom, A.R.5    Heiss, G.6    Sharrett, A.R.7
  • 52
    • 13444268943 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: The Rotterdam Study
    • Oei HH, van der Meer IM, Hofman A, Koudstaal PJ, Stijnen T, Breteler MM, Witteman JC. Lipoprotein-associated phospholipase A2 activity is associated with risk of coronary heart disease and ischemic stroke: the Rotterdam Study. Circulation 2005;111(5):570-5.
    • (2005) Circulation , vol.111 , Issue.5 , pp. 570-575
    • Oei, H.H.1    van der Meer, I.M.2    Hofman, A.3    Koudstaal, P.J.4    Stijnen, T.5    Breteler, M.M.6    Witteman, J.C.7
  • 53
    • 46349090680 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A2 and myocardial infarction in women
    • [abstract]
    • Hatoum IJ, Nelson JJ, Rexrode K, Manson J, Rimm EB. Lipoprotein-associated phospholipase A2 and myocardial infarction in women [abstract]. Circulation 2007;116:II-818.
    • (2007) Circulation , vol.116
    • Hatoum, I.J.1    Nelson, J.J.2    Rexrode, K.3    Manson, J.4    Rimm, E.B.5
  • 54
    • 0034035763 scopus 로고    scopus 로고
    • Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase: A potential new risk factor for coronary artery disease
    • Caslake MJ, Packard CJ, Suckling KE, Holmes SD, Chamberlain P, Macphee CH. Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease. Atherosclerosis 2000; 150(2):413-9.
    • (2000) Atherosclerosis , vol.150 , Issue.2 , pp. 413-419
    • Caslake, M.J.1    Packard, C.J.2    Suckling, K.E.3    Holmes, S.D.4    Chamberlain, P.5    Macphee, C.H.6
  • 55
    • 0142010569 scopus 로고    scopus 로고
    • Plasma PAF-acetylhydrolase in patients with coronary artery disease: Results of a cross-sectional analysis
    • Blankenberg S, Stengel D, Rupprecht HJ, Bickel C, Meyer J, Cambien F, et al. Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis. J Lipid Res 2003;44(7):1381-6.
    • (2003) J Lipid Res , vol.44 , Issue.7 , pp. 1381-1386
    • Blankenberg, S.1    Stengel, D.2    Rupprecht, H.J.3    Bickel, C.4    Meyer, J.5    Cambien, F.6
  • 56
    • 23944434921 scopus 로고    scopus 로고
    • Association between Lp-PLA2 and coronary artery disease: Focus on its relationship with lipoproteins and markers of inflammation and hemostasis
    • Khuseyinova N, Imhof A, Rothenbacher D, Trischler G, Kuelb S, Scharnagl H, et al. Association between Lp-PLA2 and coronary artery disease: focus on its relationship with lipoproteins and markers of inflammation and hemostasis. Atherosclerosis 2005;182(1):181-8.
    • (2005) Atherosclerosis , vol.182 , Issue.1 , pp. 181-188
    • Khuseyinova, N.1    Imhof, A.2    Rothenbacher, D.3    Trischler, G.4    Kuelb, S.5    Scharnagl, H.6
  • 57
    • 14844340572 scopus 로고    scopus 로고
    • Platelet-activating factor acetylhydrolase activity indicates angiographic coronary artery disease independently of systemic inflammation and other risk factors: The Ludwigshafen Risk and Cardiovascular Health Study [published erratum appears in Circulation 2005;111 (24):E444]
    • Winkler K, Winkelmann BR, Scharnagl H, Hoffmann MM, Grawitz AB, Nauck M, et al. Platelet-activating factor acetylhydrolase activity indicates angiographic coronary artery disease independently of systemic inflammation and other risk factors: the Ludwigshafen Risk and Cardiovascular Health Study [published erratum appears in Circulation 2005;111 (24):e444]. Circulation 2005;111(8):980-7.
    • (2005) Circulation , vol.111 , Issue.8 , pp. 980-987
    • Winkler, K.1    Winkelmann, B.R.2    Scharnagl, H.3    Hoffmann, M.M.4    Grawitz, A.B.5    Nauck, M.6
  • 58
    • 32844458768 scopus 로고    scopus 로고
    • Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkers
    • Johnston N, Jernberg T, Lagerqvist B, Siegbahn A, Wallentin L. Improved identification of patients with coronary artery disease by the use of new lipid and lipoprotein biomarkers. Am J Cardiol 2006;97(5):640-5.
    • (2006) Am J Cardiol , vol.97 , Issue.5 , pp. 640-645
    • Johnston, N.1    Jernberg, T.2    Lagerqvist, B.3    Siegbahn, A.4    Wallentin, L.5
  • 59
    • 33947311044 scopus 로고    scopus 로고
    • Lipoproteinassociated phospholipase A2 does not predict mortality or new ischaemic events in acute coronary syndrome patients
    • Oldgren J, James SK, Siegbahn A, Wallentin L. Lipoproteinassociated phospholipase A2 does not predict mortality or new ischaemic events in acute coronary syndrome patients. Eur Heart J 2007;28(6):699-704.
    • (2007) Eur Heart J , vol.28 , Issue.6 , pp. 699-704
    • Oldgren, J.1    James, S.K.2    Siegbahn, A.3    Wallentin, L.4
  • 60
    • 44649097081 scopus 로고    scopus 로고
    • Cardiovascular events with increased lipoprotein-associated phospholipase A(2) and low high-density lipoprotein-cholesterol: The Veterans Affairs HDL Intervention Trial
    • Robins SJ, Collins D, Nelson JJ, Bloomfield HE, Asztalos BF. Cardiovascular events with increased lipoprotein-associated phospholipase A(2) and low high-density lipoprotein-cholesterol: the Veterans Affairs HDL Intervention Trial. Arterioscler Thromb Vasc Biol 2008;28(6):1172-8.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.6 , pp. 1172-1178
    • Robins, S.J.1    Collins, D.2    Nelson, J.J.3    Bloomfield, H.E.4    Asztalos, B.F.5
  • 61
    • 43249125990 scopus 로고    scopus 로고
    • Distribution and correlates of lipoprotein-associated phospholipase A2 in an elderly cohort: The Cardiovascular Health Study
    • Furberg CD, Nelson JJ, Solomon C, Cushman M, Jenny NS, Psaty BM. Distribution and correlates of lipoprotein-associated phospholipase A2 in an elderly cohort: the Cardiovascular Health Study. J Am Geriatr Soc 2008;56(5):792-9.
    • (2008) J Am Geriatr Soc , vol.56 , Issue.5 , pp. 792-799
    • Furberg, C.D.1    Nelson, J.J.2    Solomon, C.3    Cushman, M.4    Jenny, N.S.5    Psaty, B.M.6
  • 63
    • 0027394125 scopus 로고
    • Variation in plasma platelet-activating factor degradation and serum lipids after acute myocardial infarction
    • Stephens CJ, Graham RM, Sturm MJ, Richardson M, Taylor RR. Variation in plasma platelet-activating factor degradation and serum lipids after acute myocardial infarction. Coron Artery Dis 1993;4(2):187-93.
    • (1993) Coron Artery Dis , vol.4 , Issue.2 , pp. 187-193
    • Stephens, C.J.1    Graham, R.M.2    Sturm, M.J.3    Richardson, M.4    Taylor, R.R.5
  • 64
    • 1842587885 scopus 로고    scopus 로고
    • C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease
    • Danesh J, Wheeler JG, Hirschfield GM, Eda S, Eiriksdottir G, Rumley A, et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med 2004;350(14):1387-97.
    • (2004) N Engl J Med , vol.350 , Issue.14 , pp. 1387-1397
    • Danesh, J.1    Wheeler, J.G.2    Hirschfield, G.M.3    Eda, S.4    Eiriksdottir, G.5    Rumley, A.6
  • 65
    • 33745827409 scopus 로고    scopus 로고
    • An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: The atherosclerosis risk in communities study
    • Folsom AR, Chambless LE, Ballantyne CM, Coresh J, Heiss G, Wu KK, et al. An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study. Arch Intern Med 2006;166(13):1368-73.
    • (2006) Arch Intern Med , vol.166 , Issue.13 , pp. 1368-1373
    • Folsom, A.R.1    Chambless, L.E.2    Ballantyne, C.M.3    Coresh, J.4    Heiss, G.5    Wu, K.K.6
  • 66
    • 0032851173 scopus 로고    scopus 로고
    • Complement and atherogenesis: Binding of CRP to degraded, nonoxidized LDL enhances complement activation
    • Bhakdi S, Torzewski M, Klouche M, Hemmes M. Complement and atherogenesis: binding of CRP to degraded, nonoxidized LDL enhances complement activation. Arterioscler Thromb Vasc Biol 1999;19(10):2348-54.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , Issue.10 , pp. 2348-2354
    • Bhakdi, S.1    Torzewski, M.2    Klouche, M.3    Hemmes, M.4
  • 67
    • 0033386090 scopus 로고    scopus 로고
    • Inf lammation markers and coronary heart disease
    • Tracy RP. Inf lammation markers and coronary heart disease. Curr Opin Lipidol 1999;10(5):435-41.
    • (1999) Curr Opin Lipidol , vol.10 , Issue.5 , pp. 435-441
    • Tracy, R.P.1
  • 68
    • 51749093324 scopus 로고    scopus 로고
    • Consensus panel recommendation for incorporating lipoprotein-associated phospholipase A2 testing into cardiovascular disease risk assessment guidelines
    • Davidson MH, Corson MA, Alberts MJ, Anderson JL, Gorelick PB, Jones PH, et al. Consensus panel recommendation for incorporating lipoprotein-associated phospholipase A2 testing into cardiovascular disease risk assessment guidelines. Am J Cardiol 2008;101(12A):51F-57F.
    • (2008) Am J Cardiol , vol.101 , Issue.12 A
    • Davidson, M.H.1    Corson, M.A.2    Alberts, M.J.3    Anderson, J.L.4    Gorelick, P.B.5    Jones, P.H.6
  • 69
    • 66349111734 scopus 로고    scopus 로고
    • Criteria for evaluation of novel markers of cardiovascular risk: A scientific statement from the American Heart Association
    • Hlatky MA, Greenland P, Arnett DK, Ballantyne CM, Criqui MH, Elkind MS, et al. Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association. Circulation 2009;119(17):2408-16.
    • (2009) Circulation , vol.119 , Issue.17 , pp. 2408-2416
    • Hlatky, M.A.1    Greenland, P.2    Arnett, D.K.3    Ballantyne, C.M.4    Criqui, M.H.5    Elkind, M.S.6
  • 71
    • 54049152760 scopus 로고    scopus 로고
    • Effects of the direct lipoproteinassociated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque
    • Serruys PW, Garcia-Garcia HM, Buszman P, Erne P, Verheye S, Aschermann M, et al. Effects of the direct lipoproteinassociated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation 2008;118(11): 1172-82.
    • (2008) Circulation , vol.118 , Issue.11 , pp. 1172-1182
    • Serruys, P.W.1    Garcia-Garcia, H.M.2    Buszman, P.3    Erne, P.4    Verheye, S.5    Aschermann, M.6
  • 72
    • 43049122963 scopus 로고    scopus 로고
    • The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: The results of a multicenter, randomized, double-blind, placebo-controlled study
    • Mohler ER 3rd, Ballantyne CM, Davidson MH, Hanefeld M, Ruilope LM, Johnson JL, Zalewski A. The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study. J Am Coll Cardiol 2008;51(17): 1632-41.
    • (2008) J Am Coll Cardiol , vol.51 , Issue.17 , pp. 1632-1641
    • Mohler 3rd, E.R.1    Ballantyne, C.M.2    Davidson, M.H.3    Hanefeld, M.4    Ruilope, L.M.5    Johnson, J.L.6    Zalewski, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.