-
1
-
-
0019940459
-
Enhancement of rat brain catecholamine synthesis by administration of small doses of tyrosine and evidence for substrate inhibition of tyrosine hydroxylase activity by large doses of the amino acid
-
A.A. Badawy, and D.L. Williams Enhancement of rat brain catecholamine synthesis by administration of small doses of tyrosine and evidence for substrate inhibition of tyrosine hydroxylase activity by large doses of the amino acid Biochem. J. 206 1982 165 168 (Pubitemid 12052613)
-
(1982)
Biochemical Journal
, vol.206
, Issue.1
, pp. 165-168
-
-
Badawy, A.A.B.1
Williams, D.L.2
-
2
-
-
0019407894
-
Mesocortical dopamine neurons: Rapid transmitter turnover compared to other brain catecholamine systems
-
M.J. Bannon, E.B. Bunney, and R.H. Roth Mesocortical dopamine neurons: rapid transmitter turnover compared to other brain catecholamine systems Brain Res. 218 1981 376 382 (Pubitemid 11083190)
-
(1981)
Brain Research
, vol.218
, Issue.1-2
, pp. 376-382
-
-
Bannon, M.J.1
Bunney, E.B.2
Roth, R.H.3
-
3
-
-
0019361193
-
Mesocortical dopamine neurons. Lack of autoreceptors modulating dopamine synthesis
-
M.J. Bannon, R.L. Michaud, and R.H. Roth Mesocortical dopamine neurons: lack of autoreceptors modulating dopamine synthesis Mol. Pharmacol. 19 1981 270 275 (Pubitemid 11004230)
-
(1981)
Molecular Pharmacology
, vol.19
, Issue.2
, pp. 270-275
-
-
Bannon, M.J.1
Michaud, R.L.2
Roth, R.H.3
-
4
-
-
77952106838
-
Relationships between large neutral amino acid levels in plasma, cerebrospinal fluid, brain microdialysate and brain tissue in the rat
-
R. Bongiovanni, B. Kirkbride, E. Newbould, V. Durkalski, and G.E. Jaskiw Relationships between large neutral amino acid levels in plasma, cerebrospinal fluid, brain microdialysate and brain tissue in the rat Brain Res. 1334 2010 45 57
-
(2010)
Brain Res.
, vol.1334
, pp. 45-57
-
-
Bongiovanni, R.1
Kirkbride, B.2
Newbould, E.3
Durkalski, V.4
Jaskiw, G.E.5
-
5
-
-
24044551622
-
Tyrosine administration does not affect desipramine-induced dopamine levels as measured in vivo in prefrontal cortex
-
DOI 10.1016/j.brainres.2005.06.070, PII S0006899305009984
-
R. Bongiovanni, B. Kirkbride, P. Walmire, and G.E. Jaskiw Tyrosine administration does not affect desipramine-induced dopamine levels as measured in vivo in prefrontal cortex Brain Res. 1054 2005 203 206 (Pubitemid 41219351)
-
(2005)
Brain Research
, vol.1054
, Issue.2
, pp. 203-206
-
-
Bongiovanni, R.1
Kirkbride, B.2
Walmire, P.3
Jaskiw, G.E.4
-
6
-
-
37549013794
-
Tyrosine depletion lowers dopamine synthesis and desipramine-induced prefrontal cortex catecholamine levels
-
R. Bongiovanni, E. Newbould, and G.E. Jaskiw Tyrosine depletion lowers dopamine synthesis and desipramine-induced prefrontal cortex catecholamine levels Brain Res. 1190 2008 39 48
-
(2008)
Brain Res.
, vol.1190
, pp. 39-48
-
-
Bongiovanni, R.1
Newbould, E.2
Jaskiw, G.E.3
-
8
-
-
84862679219
-
Dopamine in the hippocampus is cleared by the norepinephrine transporter
-
A. Borgkvist, T. Malmlof, K. Feltmann, M. Lindskog, and B. Schilstrom Dopamine in the hippocampus is cleared by the norepinephrine transporter Int. J. Neuropsychopharmacol. 15 2012 531 540
-
(2012)
Int. J. Neuropsychopharmacol.
, vol.15
, pp. 531-540
-
-
Borgkvist, A.1
Malmlof, T.2
Feltmann, K.3
Lindskog, M.4
Schilstrom, B.5
-
9
-
-
0024343138
-
Regionally-specific alterations in mesotelencephalic dopamine synthesis in diabetic rats: Association with precursor tyrosine
-
C.W. Bradberry, D.H. Karasic, A.Y. Deutch, and R.H. Roth Regionally-specific alterations in mesotelencephalic dopamine synthesis in diabetic rats: association with precursor tyrosine J. Neural Transm. 78 1989 221 229 (Pubitemid 19264986)
-
(1989)
Journal of Neural Transmission - General Section
, vol.78
, Issue.3
, pp. 221-229
-
-
Bradberry, C.W.1
Karasic, D.H.2
Deutch, A.Y.3
Roth, R.H.4
-
10
-
-
0025327748
-
Striatal L-dopa metabolism studied in vivo in rats with nigrostriatal lesions
-
DOI 10.1007/BF02251242
-
T. Brannan, A. Bhardwaj, J. Martinez-Tica, J. Weinberger, and M. Yahr Striatal l-dopa metabolism studied in vivo in rats with nigrostriatal lesions J. Neural Transm. Parkinsons Dis. Dementia Sect. 2 1990 15 22 (Pubitemid 20215378)
-
(1990)
Journal of Neural Transmission - Parkinson's Disease and Dementia Section
, vol.2
, Issue.1
, pp. 15-22
-
-
Brannan, T.1
Bhardwaj, A.2
Martinez-Tica, J.3
Weinberger, J.4
Yahr, M.5
-
11
-
-
30644462844
-
L-tyrosine contributes to (+)-3,4-methylenedioxymethamphetamine-induced serotonin depletions
-
DOI 10.1523/JNEUROSCI.3353-05.2006
-
J.M. Breier, M.G. Bankson, and B.K. Yamamoto l-tyrosine contributes to (+)-3,4-methylenedioxymethamphetamine-induced serotonin depletions J. Neurosci. 26 2006 290 299 (Pubitemid 43089542)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.1
, pp. 290-299
-
-
Breier, J.M.1
Bankson, M.G.2
Yamamoto, B.K.3
-
12
-
-
0015440803
-
Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase
-
A. Carlsson, J.N. Davis, W. Kehr, M. Lindqvist, and C.V. Atack Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase Naunyn Schmiedebergs Arch. Pharmacol. 275 1972 153 168
-
(1972)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.275
, pp. 153-168
-
-
Carlsson, A.1
Davis, J.N.2
Kehr, W.3
Lindqvist, M.4
Atack, C.V.5
-
13
-
-
0018104243
-
Dependence of 5-HT and catecholamine synthesis on concentrations of precursor amino-acids in rat brain
-
A. Carlsson, and M. Lindqvist Dependence of 5-HT and catecholamine synthesis on precursor amino-acid levels in rat brain Naunyn-Schmiedberg's Arch. Pharmacol. 303 1978 157 164 (Pubitemid 8369123)
-
(1978)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.303
, Issue.2
, pp. 157-164
-
-
Carlsson, A.1
Lindqvist, M.2
-
14
-
-
76249088643
-
A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles
-
E.A. Cartier, L.A. Parra, T.B. Baust, M. Quiroz, G. Salazar, V. Faundez, L. Egana, and G.E. Torres A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles J. Biol. Chem. 285 2010 1957 1966
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1957-1966
-
-
Cartier, E.A.1
Parra, L.A.2
Baust, T.B.3
Quiroz, M.4
Salazar, G.5
Faundez, V.6
Egana, L.7
Torres, G.E.8
-
15
-
-
0031596987
-
3H]tyrosine in living rat brain is not committed to dopamine synthesis
-
P. Cumming, A. Ase, H. Kuwabara, and A. Gjedde [3H]DOPA formed from [3H]tyrosine in living rat brain is not committed to dopamine synthesis J. Cereb. Blood Flow Metab. 18 1998 491 499 (Pubitemid 28213533)
-
(1998)
Journal of Cerebral Blood Flow and Metabolism
, vol.18
, Issue.5
, pp. 491-499
-
-
Cumming, P.1
Ase, A.2
Kuwabara, H.3
Gjedde, A.4
-
16
-
-
0034672439
-
Methodological issues in microdialysis sampling for pharmacokinetic studies
-
E.C. de Lange, A.G. de Boer, and D.D. Breimer Methodological issues in microdialysis sampling for pharmacokinetic studies Adv. Drug Delivery Rev. 45 2000 125 148
-
(2000)
Adv. Drug Delivery Rev.
, vol.45
, pp. 125-148
-
-
De Lange, E.C.1
De Boer, A.G.2
Breimer, D.D.3
-
17
-
-
50449097993
-
Pharmacokinetic role of l-type amino acid transporters LAT1 and LAT2
-
E.M. del Amo, A. Urtti, and M. Yliperttula Pharmacokinetic role of l-type amino acid transporters LAT1 and LAT2 Eur. J. Pharm. Sci. 35 2008 161 174
-
(2008)
Eur. J. Pharm. Sci.
, vol.35
, pp. 161-174
-
-
Del Amo, E.M.1
Urtti, A.2
Yliperttula, M.3
-
18
-
-
0023244633
-
Effect of decarboxylase inhibitors on brain p-tyrosine levels
-
DOI 10.1016/0006-2952(87)90097-9
-
L.E. Dyck Effect of decarboxylase inhibitors on brain p-tyrosine levels Biochem. Pharmacol. 36 1987 1373 1376 (Pubitemid 17083199)
-
(1987)
Biochemical Pharmacology
, vol.36
, Issue.8
, pp. 1373-1376
-
-
Dyck, L.E.1
-
19
-
-
4143144205
-
Catecholamine metabolism: A contemporary view with implications for physiology and medicine
-
DOI 10.1124/pr.56.3.1
-
G. Eisenhofer, I.J. Kopin, and D.S. Goldstein Catecholamine metabolism: a contemporary view with implications for physiology and medicine Pharmacol. Rev. 56 2004 331 349 (Pubitemid 39096594)
-
(2004)
Pharmacological Reviews
, vol.56
, Issue.3
, pp. 331-349
-
-
Eisenhofer, G.1
Kopin, I.J.2
Goldstein, D.S.3
-
20
-
-
0021341164
-
Evidence for dopamine autoreceptors in mesocortical dopamine neurons
-
DOI 10.1016/0006-8993(84)91453-7
-
F. Fadda, G.L. Gessa, M. Marcou, E. Mosca, and Z. Rossetti Evidence for dopamine autoreceptors in mesocortical dopamine neurons Brain Res. 293 1984 67 72 (Pubitemid 14150185)
-
(1984)
Brain Research
, vol.293
, Issue.1
, pp. 67-72
-
-
Fadda, F.1
Gessa, G.L.2
Marcou, M.3
-
21
-
-
0022558605
-
Regulation ogf dopamine synthesis in the medial prefrontal cortex is mediated by release modulating autoreceptors: Studies in vivo
-
M.P. Galloway, M.E. Wolf, and R.H. Roth Regulation of dopamine synthesis in the medial prefrontal cortex is mediated by release modulating autoreceptors: studies in vivo J. Pharmacol. Exp. Ther. 236 1986 689 698 (Pubitemid 16080067)
-
(1986)
Journal of Pharmacology and Experimental Therapeutics
, vol.236
, Issue.3
, pp. 689-698
-
-
Galloway, M.P.1
Wolf, M.E.2
Roth, R.H.3
-
22
-
-
0028555344
-
Mesolimbic dopaminergic neurons innervating the hippocampal formation in the rat: A combined retrograde tracing and immunohistochemical study
-
A. Gasbarri, C. Verney, R. Innocenzi, E. Campana, and C. Pacitti Mesolimbic dopaminergic neurons innervating the hippocampal formation in the rat: a combined retrograde tracing and immunohistochemical study Brain Res. 668 1994 71 79
-
(1994)
Brain Res.
, vol.668
, pp. 71-79
-
-
Gasbarri, A.1
Verney, C.2
Innocenzi, R.3
Campana, E.4
Pacitti, C.5
-
23
-
-
0035171590
-
Novel aspects of dopamine oxidative metabolism (Confounding outcomes take place of certainties)
-
M. Gesi, A. Santinami, R. Ruffoli, G. Conti, and F. Fornai Novel aspects of dopamine oxidative metabolism (confounding outcomes take place of certainties) Pharmacol. Toxicol. 89 2001 217 224 (Pubitemid 33070921)
-
(2001)
Pharmacology and Toxicology
, vol.89
, Issue.5
, pp. 217-224
-
-
Fornai, F.1
-
24
-
-
0032809060
-
Interaction between L-DOPA and 3-O-methyl-L-DOPA for transport in immortalised rat capillary cerebral endothelial cells
-
DOI 10.1016/S0028-3908(99)00042-8, PII S0028390899000428
-
P. Gomes, and P. Soares-da-Silva Interaction between l-DOPA and 3-O-methyl-l-DOPA for transport in immortalised rat capillary cerebral endothelial cells Neuropharmacology 38 1999 1371 1380 (Pubitemid 29333153)
-
(1999)
Neuropharmacology
, vol.38
, Issue.9
, pp. 1371-1380
-
-
Gomes, P.1
Soares-Da-Silva, P.2
-
25
-
-
0021149498
-
Effects of the noradrenaline neurotoxin DSP4 on monoamine neurons and their transmitter turnover in rat CNS
-
H. Hallman, E. Sundstrom, and G. Jonsson Effects of the noradrenaline neurotoxin DSP 4 on monoamine neurons and their transmitter turnover in rat CNS J. Neural Transm. 60 1984 89 102 (Pubitemid 14035427)
-
(1984)
Journal of Neural Transmission - General Section
, vol.60
, Issue.2
, pp. 89-102
-
-
Hallman, H.1
Sundstrom, E.2
Jonsson, G.3
-
26
-
-
30544452029
-
Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats
-
DOI 10.1038/sj.bjp.0706288
-
I. Hatip-Al-Khatib, K. Iwasaki, Y. Yoshimitsu, T. Arai, N. Egashira, K. Mishima, T. Ikeda, and M. Fujiwara Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats Br. J. Pharmacol. 145 2005 1035 1044 (Pubitemid 43079975)
-
(2005)
British Journal of Pharmacology
, vol.145
, Issue.8
, pp. 1035-1044
-
-
Hatip-Al-Khatib, I.1
Iwasaki, K.2
Yoshimitsu, Y.3
Arai, T.4
Egashira, N.5
Mishima, K.6
Ikeda, T.7
Fujiwara, M.8
-
27
-
-
33646677965
-
Phasic dopamine signaling during behavior, reward, and disease states
-
M.L. Heien, and R.M. Wightman Phasic dopamine signaling during behavior, reward, and disease states CNS Neurol. Disord. Drug Targets 5 2006 99 108 (Pubitemid 43796629)
-
(2006)
CNS and Neurological Disorders - Drug Targets
, vol.5
, Issue.1
, pp. 99-108
-
-
Heien, M.L.A.V.1
Wightman, R.M.2
-
28
-
-
0018147715
-
Effects of histidine on the transport of L-DOPA by slices of brain cortex and striatum of the rat
-
B. Herreros, J. Garcia-Sancho, and E. Barbosa Effects of histidine on the transport of l-dopa by slices of brain cortex and striatum of the rat J. Neurochem. 30 1978 1101 1104 (Pubitemid 8367698)
-
(1978)
Journal of Neurochemistry
, vol.30
, Issue.5
, pp. 1101-1104
-
-
Herreros, B.1
Garcia-Sancho, J.2
Barbosa, E.3
-
29
-
-
0026046022
-
Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus
-
H. Hortnagl, M.L. Berger, G. Sperk, and C. Pifl Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus Neuroscience 45 1991 261 272
-
(1991)
Neuroscience
, vol.45
, pp. 261-272
-
-
Hortnagl, H.1
Berger, M.L.2
Sperk, G.3
Pifl, C.4
-
30
-
-
53949102049
-
Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus
-
M. Huang, Z. Li, J. Dai, M. Shahid, E.H. Wong, and H.Y. Meltzer Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus Neuropsychopharmacology 33 2008 2934 2945
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2934-2945
-
-
Huang, M.1
Li, Z.2
Dai, J.3
Shahid, M.4
Wong, E.H.5
Meltzer, H.Y.6
-
31
-
-
0033766209
-
Effect of corticotropin releasing factor receptor 1 antagonist on extracellular norepinephrine, dopamine and serotonin in hippocampus and prefrontal cortex of rats in vivo
-
K. Isogawa, J. Akiyoshi, T. Hikichi, Y. Yamamoto, T. Tsutsumi, and H. Nagayama Effect of corticotropin releasing factor receptor 1 antagonist on extracellular norepinephrine, dopamine and serotonin in hippocampus and prefrontal cortex of rats in vivo Neuropeptides 34 2000 234 239
-
(2000)
Neuropeptides
, vol.34
, pp. 234-239
-
-
Isogawa, K.1
Akiyoshi, J.2
Hikichi, T.3
Yamamoto, Y.4
Tsutsumi, T.5
Nagayama, H.6
-
32
-
-
0022495124
-
Tyrosine hydroxylase activation in mesocortical 3,4- dihydroxyphenylethylamine neurons following footshock
-
P.M. Iuvone, and A.J. Dunn Tyrosine hydroxylase activation in mesocortical 3,4-dihydroxyphenylethylamine neurons following footshock J. Neurochem. 47 1986 837 844 (Pubitemid 16029566)
-
(1986)
Journal of Neurochemistry
, vol.47
, Issue.3
, pp. 837-844
-
-
Iuvone, P.M.1
Dunn, A.J.2
-
33
-
-
33645455400
-
In rats chronically treated with clozapine, tyrosine depletion attenuates the clozapine-induced in vivo increase in prefrontal cortex dopamine and norepinephrine levels
-
G.E. Jaskiw, B. Kirkbride, and R. Bongiovanni In rats chronically treated with clozapine, tyrosine depletion attenuates the clozapine-induced in vivo increase in prefrontal cortex dopamine and norepinephrine levels Psychopharmacology (Berl.) 185 2006 416 422
-
(2006)
Psychopharmacology (Berl.)
, vol.185
, pp. 416-422
-
-
Jaskiw, G.E.1
Kirkbride, B.2
Bongiovanni, R.3
-
34
-
-
20044377273
-
Clozapine-induced dopamine release in the medial prefrontal cortex is augmented by a moderate concentration of locally administered tyrosine but attenuated by high tyrosine concentrations or by tyrosine depletion
-
DOI 10.1007/s00213-004-2091-4
-
G.E. Jaskiw, B. Kirkbride, E. Newbould, D. Young, V. Durkalski, and R. Bongiovanni Clozapine-induced dopamine release in the medial prefrontal cortex is augmented by a moderate concentration of locally administered tyrosine but attenuated by high tyrosine concentrations or by tyrosine depletion Psychopharmacology (Berl.) 179 2005 713 724 (Pubitemid 40767892)
-
(2005)
Psychopharmacology
, vol.179
, Issue.4
, pp. 713-724
-
-
Jaskiw, G.E.1
Kirkbride, B.2
Newbould, E.3
Young, D.4
Durkalski, V.5
Bongiovanni, R.6
-
35
-
-
0442276446
-
Tyrosine augments clozapine-induced dopamine release in the medial prefrontal cortex of the rat in vivo: Effects of access to food
-
DOI 10.1016/j.neulet.2003.11.060
-
G.E. Jaskiw, C. Simpson, R. Bongiovanni, and B.K. Yamamoto Tyrosine augments clozapine-induced dopamine release in the medial prefrontal cortex of the rat in vivo: effects of access to food Neurosci. Lett. 357 2004 5 8 (Pubitemid 38186657)
-
(2004)
Neuroscience Letters
, vol.357
, Issue.1
, pp. 5-8
-
-
Jaskiw, G.E.1
Simpson, C.2
Bongiovanni, R.3
Yamamoto, B.K.4
-
36
-
-
0032584230
-
Profound neuronal plasticity in response to inactivation of the dopamine transporter
-
DOI 10.1073/pnas.95.7.4029
-
S.R. Jones, R.R. Gainetdinov, M. Jaber, B. Giros, R.M. Wightman, and M.G. Caron Profound neuronal plasticity in response to inactivation of the dopamine transporter Proc. Natl. Acad. Sci. USA 95 1998 4029 4034 (Pubitemid 28173248)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.7
, pp. 4029-4034
-
-
Jones, S.R.1
Gainetdinov, R.R.2
Jaber, M.3
Giros, B.4
Wightman, R.M.5
Caron, M.G.6
-
37
-
-
77956327951
-
Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice
-
M. Kaenmaki, A. Tammimaki, T. Myohanen, K. Pakarinen, C. Amberg, M. Karayiorgou, J.A. Gogos, and P.T. Mannisto Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice J. Neurochem. 114 2010 1745 1755
-
(2010)
J. Neurochem.
, vol.114
, pp. 1745-1755
-
-
Kaenmaki, M.1
Tammimaki, A.2
Myohanen, T.3
Pakarinen, K.4
Amberg, C.5
Karayiorgou, M.6
Gogos, J.A.7
Mannisto, P.T.8
-
39
-
-
0022446040
-
Restricted diffusion of tyrosine hydroxylase and phenylethanolamine N-methyltransferase from digitonin-permeabilized adrenal chromaffin cells
-
K.L. Kelner, K. Morita, J.S. Rossen, and H.B. Pollard Restricted diffusion of tyrosine hydroxylase and phenylethanolamine N-methyltransferase from digitonin-permeabilized adrenal chromaffin cells Proc. Natl. Acad. Sci. USA 83 1986 2998 3002 (Pubitemid 16041789)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.9
, pp. 2998-3002
-
-
Kelner, K.L.1
Morita, K.2
Rossen, J.S.3
Pollard, H.B.4
-
40
-
-
0023485299
-
Absence of synthesis-modulating nerve terminal autoreceptors on mesoamygdaloid and other mesolimbic dopamine neuronal populations
-
C.D. Kilts, C.M. Anderson, T.D. Ely, and J.K. Nishita Absence of synthesis-modulating nerve terminal autoreceptors on mesoamygdaloid and other mesolimbic dopamine neuronal populations J. Neurosci. 7 1987 3961 3975 (Pubitemid 18012409)
-
(1987)
Journal of Neuroscience
, vol.7
, Issue.12
, pp. 3961-3975
-
-
Kilts, C.D.1
Anderson, C.M.2
Ely, T.D.3
Nishita, J.K.4
-
41
-
-
0035968052
-
Regulation of expression and enzymatic activities of tyrosine and tryptophan hydroxylases in rat brain after acute electroconvulsive shock
-
DOI 10.1016/S0006-8993(01)02524-0, PII S0006899301025240
-
D. Koubi, L. Bezin, J.M. Cottet-Emard, A. Gharib, P. Bobillier, and N. Sarda Regulation of expression and enzymatic activities of tyrosine and tryptophan hydroxylases in rat brain after acute electroconvulsive shock Brain Res. 905 2001 161 170 (Pubitemid 32553850)
-
(2001)
Brain Research
, vol.905
, Issue.1-2
, pp. 161-170
-
-
Koubi, D.1
Bezin, L.2
Cottet-Emard, J.-M.3
Gharib, A.4
Bobillier, P.5
Sarda, N.6
-
42
-
-
0015523045
-
Regulatory properties of soluble and particulate rat brain tyrosine hydroxylase
-
R.T. Kuczenski, and A.J. Mandell Regulatory properties of soluble and particulate rat brain tyrosine hydroxylase J. Biol. Chem. 247 1972 3114 3122
-
(1972)
J. Biol. Chem.
, vol.247
, pp. 3114-3122
-
-
Kuczenski, R.T.1
Mandell, A.J.2
-
43
-
-
0025234950
-
Tyrosine hydroxylase in secretory granules from bovine adrenal medulla. Evidence for an integral membrane form
-
D.M. Kuhn, R. Arthur Jr.; H. Yoon, and K. Sankaran Tyrosine hydroxylase in secretory granules from bovine adrenal medulla. Evidence for an integral membrane form J. Biol. Chem. 265 1990 5780 5786
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 5780-5786
-
-
Kuhn, D.M.1
Arthur Jr., R.2
Yoon, H.3
Sankaran, K.4
-
44
-
-
0034079913
-
Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter
-
DOI 10.1007/s002100000246
-
I. Lamensdorf, C. Hrycyna, L.P. He, A. Nechushtan, O. Tjurmina, J. Harvey-White, G. Eisenhofer, E. Rojas, and I.J. Kopin Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter Naunyn Schmiedebergs Arch. Pharmacol. 361 2000 654 664 (Pubitemid 30350843)
-
(2000)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.361
, Issue.6
, pp. 654-664
-
-
Lamensdorf, I.1
Hrycyna, C.2
He, L.-P.3
Nechushtan, A.4
Tjurmina, O.5
Harvey-White, J.6
Eisenhofer, G.7
Rojas, E.8
Kopin, I.J.9
-
45
-
-
34548797583
-
1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus
-
DOI 10.1016/j.ejphar.2007.06.025, PII S0014299907007273
-
Z. Li, D.W. Bonhaus, M. Huang, A.J. Prus, J. Dai, and H.Y. Meltzer AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3- one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus Eur. J. Pharmacol. 572 2007 129 137 (Pubitemid 47429641)
-
(2007)
European Journal of Pharmacology
, vol.572
, Issue.2-3
, pp. 129-137
-
-
Li, Z.1
Bonhaus, D.W.2
Huang, M.3
Prus, A.J.4
Dai, J.5
Meltzer, H.Y.6
-
46
-
-
0032899762
-
Effect of a tyrosine-free amino acid mixture on regional brain catecholamine synthesis and release
-
DOI 10.1007/s002130050823
-
S.F. McTavish, P.J. Cowen, and T. Sharp Effect of a tyrosine-free amino acid mixture on regional brain catecholamine synthesis and release Psychopharmacology (Berl.) 141 1999 182 188 (Pubitemid 29200170)
-
(1999)
Psychopharmacology
, vol.141
, Issue.2
, pp. 182-188
-
-
McTavish, S.F.B.1
Cowen, P.J.2
Sharp, T.3
-
47
-
-
0022485782
-
Catecholamine synthesis: Physiological coupling to precursor supply
-
DOI 10.1016/0006-2952(86)90071-7
-
J.D. Milner, and R.J. Wurtman Catecholamine synthesis: physiological coupling to precursor supply Biochem. Pharmacol. 35 1986 875 881 (Pubitemid 16019847)
-
(1986)
Biochemical Pharmacology
, vol.35
, Issue.6
, pp. 875-881
-
-
Milner, J.D.1
Wurtman, R.J.2
-
48
-
-
2442682719
-
1 receptors, on the in vivo activity of tyrosine and tryptophan hydroxylase in the rat brain
-
DOI 10.1007/s00210-004-0921-x
-
D. Moranta, S. Esteban, and J.A. Garcia-Sevilla Differential effects of acute cannabinoid drug treatment, mediated by CB1 receptors, on the in vivo activity of tyrosine and tryptophan hydroxylase in the rat brain Naunyn Schmiedebergs Arch. Pharmacol. 369 2004 516 524 (Pubitemid 38669971)
-
(2004)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.369
, Issue.5
, pp. 516-524
-
-
Moranta, D.1
Esteban, S.2
Garcia-Sevilla, J.A.3
-
49
-
-
0023664386
-
Interaction of cytoplasmic tyrosine hydroxylase with chromaffin granule. in vitro studies on association of soluble enzyme with granule membranes and alteration in enzyme activity
-
K. Morita, K. Teraoka, and M. Oka Interaction of cytoplasmic tyrosine hydroxylase with chromaffin granule. In vitro studies on association of soluble enzyme with granule membranes and alteration in enzyme activity J. Biol. Chem. 262 1987 5654 5658
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 5654-5658
-
-
Morita, K.1
Teraoka, K.2
Oka, M.3
-
50
-
-
84863403855
-
Pharmacological effects of Lu AA21004: A novel multimodal compound for the treatment of major depressive disorder
-
A. Mork, A. Pehrson, L.T. Brennum, S.M. Nielsen, H. Zhong, A.B. Lassen, S. Miller, L. Westrich, N.J. Boyle, C. Sanchez, C.W. Fischer, N. Liebenberg, G. Wegener, C. Bundgaard, S. Hogg, B. Bang-Andersen, and T.B. Stensbol Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder J. Pharmacol. Exp. Ther. 340 2012 666 675
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.340
, pp. 666-675
-
-
Mork, A.1
Pehrson, A.2
Brennum, L.T.3
Nielsen, S.M.4
Zhong, H.5
Lassen, A.B.6
Miller, S.7
Westrich, L.8
Boyle, N.J.9
Sanchez, C.10
Fischer, C.W.11
Liebenberg, N.12
Wegener, G.13
Bundgaard, C.14
Hogg, S.15
Bang-Andersen, B.16
Stensbol, T.B.17
-
51
-
-
0038383710
-
Intracellular patch electrochemistry: Regulation of cytosolic catecholamines in chromaffin cells
-
E.V. Mosharov, L.W. Gong, B. Khanna, D. Sulzer, and M. Lindau Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells J. Neurosci. 23 2003 5835 5845 (Pubitemid 36807863)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.13
, pp. 5835-5845
-
-
Mosharov, E.V.1
Gong, L.-W.2
Khanna, B.3
Sulzer, D.4
Lindau, M.5
-
52
-
-
0034607582
-
Intracranial self-stimulation increases differentially in vivo hydroxylation of tyrosine but similarly in vivo hydroxylation of tryptophan in rat medial prefrontal cortex, nucleus accumbens and striatum
-
DOI 10.1016/S0006-8993(00)02166-1, PII S0006899300021661
-
D. Nakahara, M. Nakamura, H. Furukawa, and N. Furuno Intracranial self-stimulation increases differentially in vivo hydroxylation of tyrosine but similarly in vivo hydroxylation of tryptophan in rat medial prefrontal cortex, nucleus accumbens and striatum Brain Res. 864 2000 124 129 (Pubitemid 30227605)
-
(2000)
Brain Research
, vol.864
, Issue.1
, pp. 124-129
-
-
Nakahara, D.1
Nakamura, M.2
Furukawa, H.3
Furuno, N.4
-
53
-
-
0026601110
-
Enhanced tyrosine hydroxylation in hippocampus of chronically stressed rats upon exposure to a novel stressor
-
L.K. Nisenbaum, and E.D. Abercrombie Enhanced tyrosine hydroxylation in hippocampus of chronically stressed rats upon exposure to a novel stressor J. Neurochem. 58 1992 276 281
-
(1992)
J. Neurochem.
, vol.58
, pp. 276-281
-
-
Nisenbaum, L.K.1
Abercrombie, E.D.2
-
54
-
-
0023410255
-
Turnover of dopamine and dopamine metabolites in rat brain: Comparison between striatum and substantia nigra
-
H. Nissbrandt, and A. Carlsson Turnover of dopamine and dopamine metabolites in rat brain: comparison between striatum and substantia nigra J. Neurochem. 49 1987 959 967
-
(1987)
J. Neurochem.
, vol.49
, pp. 959-967
-
-
Nissbrandt, H.1
Carlsson, A.2
-
55
-
-
0018674247
-
Distribution of norepinephrine and dopamine in cerebral cortical areas of the rat
-
DOI 10.1016/0361-9230(79)90099-6
-
M. Palkovits, L. Zaborszky, M.J. Brownstein, M.I. Fekete, J.P. Herman, and B. Kanyicska Distribution of norepinephrine and dopamine in cerebral cortical areas of the rat Brain Res. Bull. 4 1979 593 601 (Pubitemid 10246015)
-
(1979)
Brain Research Bulletin
, vol.4
, Issue.5
, pp. 593-601
-
-
Palkovits, M.1
Zaborszky, L.2
Brownstein, M.J.3
-
57
-
-
0037051136
-
Regulation of dopamine quantal size in midbrain and hippocampal neurons
-
DOI 10.1016/S0166-4328(01)00419-3, PII S0166432801004193
-
E.N. Pothos Regulation of dopamine quantal size in midbrain and hippocampal neurons Behav. Brain Res. 130 2002 203 207 (Pubitemid 34195337)
-
(2002)
Behavioural Brain Research
, vol.130
, Issue.1-2
, pp. 203-207
-
-
Pothos, E.N.1
-
58
-
-
0037101540
-
Stimulation-dependent regulation of the pH, volume and quantal size of bovine land rodent secretory vesicles
-
DOI 10.1113/jphysiol.2002.018630
-
E.N. Pothos, E. Mosharov, K.P. Liu, W. Setlik, M. Haburcak, G. Baldini, M.D. Gershon, H. Tamir, and D. Sulzer Stimulation-dependent regulation of the pH, volume and quantal size of bovine and rodent secretory vesicles J. Physiol. 542 2002 453 476 (Pubitemid 35190307)
-
(2002)
Journal of Physiology
, vol.542
, Issue.2
, pp. 453-476
-
-
Pothos, E.N.1
Mosharov, E.2
Liu, K.-P.3
Setlik, W.4
Haburcak, M.5
Baldini, G.6
Gershon, M.D.7
Tamir, H.8
Sulzer, D.9
-
59
-
-
0036138828
-
The discovery of PD 89211 and related compounds: Selective dopamine D4 receptor antagonists
-
DOI 10.1016/S0278-5846(01)00252-4, PII S0278584601002524
-
T.A. Pugsley, Y.H. Shih, S.Z. Whetzel, K. Zoski, D. Van Leeuwen, H. Akunne, R. Mackenzie, T.G. Heffner, D. Wustrow, and L.D. Wise The discovery of PD 89211 and related compounds: selective dopamine D4 receptor antagonists Prog. Neuropsychopharmacol. Biol. Psychiatry 26 2002 219 226 (Pubitemid 34038047)
-
(2002)
Progress in Neuro-Psychopharmacology and Biological Psychiatry
, vol.26
, Issue.2
, pp. 219-226
-
-
Pugsley, T.A.1
Shih, Y.H.2
Whetzel, S.Z.3
Zoski, K.4
Van Leeuwen, D.5
Akunne, H.6
Mackenzie, R.7
Heffner, T.G.8
Wustrow, D.9
Wise, L.D.10
-
60
-
-
77951761289
-
The biological significance of substrate inhibition: A mechanism with diverse functions
-
M.C. Reed, A. Lieb, and H.F. Nijhout The biological significance of substrate inhibition: a mechanism with diverse functions Bioessays 32 2010 422 429
-
(2010)
Bioessays
, vol.32
, pp. 422-429
-
-
Reed, M.C.1
Lieb, A.2
Nijhout, H.F.3
-
61
-
-
0032817435
-
Effects of imidazoline receptor ligands on monoamine synthesis in the rat brain in vivo
-
DOI 10.1007/s002109900032
-
A. Sastre-Coll, S. Esteban, and J.A. Garcia-Sevilla Effects of imidazoline receptor ligands on monoamine synthesis in the rat brain in vivo Naunyn Schmiedebergs Arch. Pharmacol. 360 1999 50 62 (Pubitemid 29354653)
-
(1999)
Naunyn-Schmiedeberg's Archives of Pharmacology
, vol.360
, Issue.1
, pp. 50-62
-
-
Sastre-Coll, A.1
Esteban, S.2
Garcia-Sevilla, J.A.3
-
62
-
-
0018345467
-
Assessment of the effects of neonatal subcutaneous 6-hydroxydopamine on noradrenergic and dopaminergic innervation of the cerebral cortex
-
DOI 10.1016/0006-8993(79)90216-6
-
R.H. Schmidt, and R.K. Bhatnagar Assessment of the effects of neonatal subcutaneous 6-hydroxydopamine on noradrenergic and dopaminergic innervation of the cerebral cortex Brain Res. 166 1979 309 319 (Pubitemid 9153497)
-
(1979)
Brain Research
, vol.166
, Issue.2
, pp. 309-319
-
-
Schmidt, R.H.1
Bhatnagar, R.K.2
-
63
-
-
0002385575
-
Blockade of endogenous norepinephrine synthesis by alpha-methyl-tyrosine, an inhibitor of tyrosine hydroxylase
-
S. Spector, A. Sjoerdsma, and S. Udenfriend Blockade of endogenous norepinephrine synthesis by alpha-methyl-tyrosine, an inhibitor of tyrosine hydroxylase J. Pharmacol. Exp. Ther. 147 1965 86 95
-
(1965)
J. Pharmacol. Exp. Ther.
, vol.147
, pp. 86-95
-
-
Spector, S.1
Sjoerdsma, A.2
Udenfriend, S.3
-
64
-
-
0019802454
-
Tyrosine availability and dopamine synthesis in the striatum: Studies with gamma-butyrolactone
-
A.F. Sved, and J.D. Fernstrom Tyrosine availability and dopamine synthesis in the striatum: Studies with gamma-butyrolactone Life Sci. 29 1981 743 748
-
(1981)
Life Sci.
, vol.29
, pp. 743-748
-
-
Sved, A.F.1
Fernstrom, J.D.2
-
65
-
-
0025360205
-
Mesocortical dopamine neurons: high basal firing frequency predicts tyrosine dependence of dopamine synthesis
-
DOI 10.1007/BF01245830
-
S.Y. Tam, J.D. Elsworth, C.W. Bradberry, and R.H. Roth Mesocortical dopamine neurons: high basal firing rate frequency predicts tyrosine dependence of dopamine synthesis J. Neural Transm. 81 1990 97 110 (Pubitemid 20175065)
-
(1990)
Journal of Neural Transmission - General Section
, vol.81
, Issue.2
, pp. 97-110
-
-
Tam, S.-Y.1
Elsworth, J.D.2
Bradberry, C.W.3
Roth, R.H.4
-
66
-
-
0029670526
-
Characterization of L-DOPA transport in cultured rat and mouse astrocytes
-
M.J. Tsai, and E.H. Lee Characterization of L-DOPA transport in cultured rat and mouse astrocytes J. Neurosci. Res. 43 1996 490 495
-
(1996)
J. Neurosci. Res.
, vol.43
, pp. 490-495
-
-
Tsai, M.J.1
Lee, E.H.2
-
67
-
-
0026741874
-
Acute administration of amphetamine: Differential regulation of dopamine synthesis in dopamine projection fields
-
C.B. Tyler, and M.P. Galloway Acute administration of amphetamine: differential regulation of dopamine synthesis in dopamine projection fields J. Pharmacol. Exp. Ther. 261 1992 567 573
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 567-573
-
-
Tyler, C.B.1
Galloway, M.P.2
-
68
-
-
0036208155
-
Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): Insights into the mechanisms of substrate recognition
-
DOI 10.1124/mol.61.4.729
-
H. Uchino, Y. Kanai, K. Kim,d.; M.F. Wempe, A. Chairoungdua, E. Morimoto, M.W. Anders, and H. Endou Transport of amino acid-related compounds mediated by l-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition Mol. Pharmacol. 61 2002 729 737 (Pubitemid 34273151)
-
(2002)
Molecular Pharmacology
, vol.61
, Issue.4
, pp. 729-737
-
-
Uchino, H.1
Kanai, Y.2
Kim, D.K.3
Wempe, M.F.4
Chairoungdua, A.5
Morimoto, E.6
Anders, M.W.7
Endou, H.8
-
69
-
-
0026542516
-
Studies on the origin of rat hippocampal dihydroxyphenylacetic acid using microdialysis
-
A. Vahabzadeh, and M. Fillenz Studies on the origin of rat hippocampal dihydroxyphenylacetic acid using microdialysis Neurosci. Lett. 136 1992 51 55
-
(1992)
Neurosci. Lett.
, vol.136
, pp. 51-55
-
-
Vahabzadeh, A.1
Fillenz, M.2
-
70
-
-
33748471284
-
Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat
-
DOI 10.1016/j.neuroscience.2006.06.027, PII S030645220600858X
-
R.P. Vertes Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat Neuroscience 142 2006 1 20 (Pubitemid 44353937)
-
(2006)
Neuroscience
, vol.142
, Issue.1
, pp. 1-20
-
-
Vertes, R.P.1
-
71
-
-
67649804671
-
14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: Localization of dopamine regulatory proteins to mitochondria
-
J. Wang, H. Lou, C.J. Pedersen, A.D. Smith, and R.G. Perez 14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria J. Biol. Chem. 284 2009 14011 14019
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 14011-14019
-
-
Wang, J.1
Lou, H.2
Pedersen, C.J.3
Smith, A.D.4
Perez, R.G.5
-
72
-
-
70350654793
-
Neuro-inflammation induced in the hippocampus of 'binge drinking rats may be mediated by elevated extracellular glutamate content
-
R.J. Ward, M.A. Colivicchi, R. Allen, F. Schol, F. Lallemand, W.P. de, C. Ballini, L.D. Corte, and D. Dexter Neuro-inflammation induced in the hippocampus of 'binge drinking rats may be mediated by elevated extracellular glutamate content J. Neurochem. 111 2009 1119 1128
-
(2009)
J. Neurochem.
, vol.111
, pp. 1119-1128
-
-
Ward, R.J.1
Colivicchi, M.A.2
Allen, R.3
Schol, F.4
Lallemand, F.5
De, W.P.6
Ballini, C.7
Corte, L.D.8
Dexter, D.9
-
73
-
-
0025156058
-
Use of microdialysis for monitoring tyrosine hydroxylase activity in the brain of conscious rats
-
B.H. Westerink, J.B. De Vries, and R. Duran Use of microdialysis for monitoring tyrosine hydroxylase activity in the brain of conscious rats J. Neurochem. 54 1990 381 387
-
(1990)
J. Neurochem.
, vol.54
, pp. 381-387
-
-
Westerink, B.H.1
De Vries, J.B.2
Duran, R.3
-
74
-
-
0020429309
-
Simultaneous determination of the formation rate of dopamine and its metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) in various rat brain areas
-
DOI 10.1016/0006-8993(82)90391-2
-
B.H. Westerink, and S.J. Spaan Simultaneous determination of the formation rate of dopamine and its metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) in various rat brain areas Brain Res. 252 1982 239 245 (Pubitemid 13238941)
-
(1982)
Brain Research
, vol.252
, Issue.2
, pp. 239-245
-
-
Westerink, B.H.C.1
Spaan, S.J.2
-
75
-
-
0020328725
-
Effects of drugs interfering with dopamine and noradrenaline biosynthesis on the endogenous 3,4-dihydroxyphenylalanine levels in rat brain
-
DOI 10.1111/j.1471-4159.1982.tb04699.x
-
B.H. Westerink, T.P. van Es, and S.J. Spaan Effects of drugs interfering with dopamine and noradrenaline biosynthesis on the endogenous 3,4-dihydroxyphenylalanine levels in rat brain J. Neurochem. 39 1982 44 51 (Pubitemid 12025924)
-
(1982)
Journal of Neurochemistry
, vol.39
, Issue.1
, pp. 44-51
-
-
Westerink, B.H.C.1
Van Es, T.P.2
Spaan, S.J.3
-
76
-
-
0020665791
-
On the significance of tyrosine for the synthesis and catabolism of dopamine in rat brain: Evaluation by HPLC with electrochemical detection
-
B.H.C. Westerink, and E. Wirix On the significance of tyrosine for the synthesis and catabolism of dopamine in rat brain: evaluation by HPLC with electrochemical detection J. Neurochem. 40 1983 758 764
-
(1983)
J. Neurochem.
, vol.40
, pp. 758-764
-
-
Westerink, B.H.C.1
Wirix, E.2
-
77
-
-
0016200122
-
Brain catechol synthesis: Control by brain tyrosine concentration
-
R.J. Wurtman, F. Larin, S. Mostafapour, and J.D. Fernstrom Brain catechol synthesis: control by brain tyrosine concentration Science 185 1974 183 184
-
(1974)
Science
, vol.185
, pp. 183-184
-
-
Wurtman, R.J.1
Larin, F.2
Mostafapour, S.3
Fernstrom, J.D.4
-
79
-
-
0242684709
-
Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine
-
DOI 10.1016/S0003-2697(02)00435-9, PII S0003269702004359
-
T. Yoshitake, K. Fujino, J. Kehr, J. Ishida, H. Nohta, and M. Yamaguchi Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine Anal. Biochem. 312 2003 125 133 (Pubitemid 36151122)
-
(2003)
Analytical Biochemistry
, vol.312
, Issue.2
, pp. 125-133
-
-
Yoshitake, T.1
Fujino, K.2
Kehr, J.3
Ishida, J.4
Nohta, H.5
Yamaguchi, M.6
-
80
-
-
0022523010
-
New sensitive high-performance liquid chromatographic method for p-tyrosine aminotransferase assay
-
P.H. Yu, and B.A. Bailey New sensitive high-performance liquid chromatographic method for p-tyrosine aminotransferase assay J. Chromatogr. 362 1986 55 59 (Pubitemid 16068294)
-
(1986)
Journal of Chromatography
, vol.362
, Issue.1
, pp. 55-59
-
-
Yu, P.H.1
Bailey, B.A.2
-
81
-
-
0029562540
-
Effects of immobilization stress on hippocampal monoamine release: Modification by mivazerol, a new alpha 2-adrenoceptor agonist
-
X. Zhang, G.H. Kindel, E. Wulfert, and I. Hanin Effects of immobilization stress on hippocampal monoamine release: modification by mivazerol, a new alpha 2-adrenoceptor agonist Neuropharmacology 34 1995 1661 1672
-
(1995)
Neuropharmacology
, vol.34
, pp. 1661-1672
-
-
Zhang, X.1
Kindel, G.H.2
Wulfert, E.3
Hanin, I.4
|