Clozapine-induced dopamine release in the medial prefrontal cortex is augmented by a moderate concentration of locally administered tyrosine but attenuated by high tyrosine concentrations or by tyrosine depletion

Psychopharmacology

Volumn 179, Issue 4, 2005, Pages 713-724

  Jaskiw, George E ^a,b   Kirkbride, Bobbi ^a   Newbould, Erica ^a   Young, Damon ^a   Durkalski, Valerie ^a   Bongiovanni, Rodolfo ^a  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Clozapine; Dopamine; Medial prefrontal cortex; Tyrosine hydroxylase

Indexed keywords

AMINO ACID; CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; PHENYLALANINE; TYROSINE;

ARTICLE; CANNULA; CEREBROSPINAL FLUID; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE BLOOD LEVEL; DOPAMINE RELEASE; DRUG BIOAVAILABILITY; MALE; MICRODIALYSIS; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE;

AMINO ACIDS; ANIMALS; ANTIPSYCHOTIC AGENTS; CLOZAPINE; DOPAMINE; EXTRACELLULAR SPACE; HALOPERIDOL; MALE; MICRODIALYSIS; NEOSTRIATUM; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; TYROSINE;

EID: 20044377273     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-004-2091-4     Document Type: Article

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