메뉴 건너뛰기




Volumn 145, Issue 8, 2005, Pages 1035-1044

Effect of oral administration of zanapezil (TAK-147) for 21 days on acetylcholine and monoamines levels in the ventral hippocampus of freely moving rats

Author keywords

Acetylcholine; Alzheimer's disease; Donepezil; Microdialysis; Monoamines; Ventral hippocampus; Zanapezil

Indexed keywords

3 O METHYLDOPAMINE; 3,4 DIHYDROXYPHENYLACETIC ACID; 4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL; 5 HYDROXYINDOLEACETIC ACID; ACETYLCHOLINE; ADRENALIN; CATECHOLAMINE; DONEPEZIL; DOPAMINE; HOMOVANILLIC ACID; INDOLEAMINE; MONOAMINE; NORADRENALIN; NORMETADRENALIN; SEROTONIN; ZANEPEZIL;

EID: 30544452029     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706288     Document Type: Article
Times cited : (16)

References (56)
  • 2
    • 0038070448 scopus 로고    scopus 로고
    • Reversal of visual attention dysfunction after AMPA lesions of the nucleus basalis magnocellularis (NBM) by the cholinesterase inhibitor donepezil and by a 5-HT1A receptor antagonist WAY 100635
    • BALDUCCI, C., NURRA, M., PIETROPOLI, A., SAMANIN, R. & CARLI, M. (2003). Reversal of visual attention dysfunction after AMPA lesions of the nucleus basalis magnocellularis (NBM) by the cholinesterase inhibitor donepezil and by a 5-HT1A receptor antagonist WAY 100635. Psychopharmacology (Berlin), 167, 28-36.
    • (2003) Psychopharmacology (Berlin) , vol.167 , pp. 28-36
    • Balducci, C.1    Nurra, M.2    Pietropoli, A.3    Samanin, R.4    Carli, M.5
  • 3
    • 0034718202 scopus 로고    scopus 로고
    • Chronic treatment of old rats with donepezil or galantamine: Effects on memory, hippocampal plasticity and nicotinic receptors
    • BARNES, C.A., MELTZER, J., HOUSTON, F., ORR, G., MCGANN, K. & WENK, G.L. (2000). Chronic treatment of old rats with donepezil or galantamine: effects on memory, hippocampal plasticity and nicotinic receptors. Neuroscience, 99, 17-23.
    • (2000) Neuroscience , vol.99 , pp. 17-23
    • Barnes, C.A.1    Meltzer, J.2    Houston, F.3    Orr, G.4    Mcgann, K.5    Wenk, G.L.6
  • 5
    • 0142216319 scopus 로고    scopus 로고
    • The effect of donepezil on sedation and other symptoms in patients receiving opioids for cancer pain: A pilot stud
    • BRUERA, E., STRASSER, F., SHEN, L., PALMER, J.L., WILLEY, J., DRIVER, L.C. & BURTON, A.W. (2003). The effect of donepezil on sedation and other symptoms in patients receiving opioids for cancer pain: a pilot stud. J. Pain Symptom Manage., 26, 1049-1054.
    • (2003) J. Pain Symptom Manage. , vol.26 , pp. 1049-1054
    • Bruera, E.1    Strasser, F.2    Shen, L.3    Palmer, J.L.4    Willey, J.5    Driver, L.C.6    Burton, A.W.7
  • 6
    • 0011195550 scopus 로고    scopus 로고
    • Reversal of scopolamine-induced spatial memory deficits in Morris water maze by TAK-147
    • CHEN, Z., XU, A.J., LI, R. & WEI, E.Q. (2002). Reversal of scopolamine-induced spatial memory deficits in Morris water maze by TAK-147. Acta Pharmacol. Sin., 19, 27-30.
    • (2002) Acta Pharmacol. Sin. , vol.19 , pp. 27-30
    • Chen, Z.1    Xu, A.J.2    Li, R.3    Wei, E.Q.4
  • 8
    • 0033805791 scopus 로고    scopus 로고
    • Alzheimer's disease: More than a 'cholinergic disorder' - Evidence that cholinergic-monoaminergic interactions contribute to EEG slowing and dementia
    • DRINGENBERG, H.C. (2000). Alzheimer's disease: more than a 'cholinergic disorder' - evidence that cholinergic-monoaminergic interactions contribute to EEG slowing and dementia. Behav. Brain Res., 115, 235-249.
    • (2000) Behav. Brain Res. , vol.115 , pp. 235-249
    • Dringenberg, H.C.1
  • 10
    • 0842325104 scopus 로고    scopus 로고
    • A randomized, placebo controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil
    • FINKEL, S.I., MINTZER, J.E., DYSKEN, M., KRISHNAN, K.R., BURT, T. & MCRAE, T. (2004). A randomized, placebo controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil. Int. J. Geriatr. Psychiatry, 19, 9-18.
    • (2004) Int. J. Geriatr. Psychiatry , vol.19 , pp. 9-18
    • Finkel, S.I.1    Mintzer, J.E.2    Dysken, M.3    Krishnan, K.R.4    Burt, T.5    McRae, T.6
  • 12
    • 0029937950 scopus 로고    scopus 로고
    • The effect of the selective reversible acetylcholinesterase inhibitor E2020 on extracellular acetylcholine and biogenic amine levels in rat cortex
    • GIACOBINI, E., ZHU, X.D., WILLIAMS, E. & SHERMAN, K.A. (1996). The effect of the selective reversible acetylcholinesterase inhibitor E2020 on extracellular acetylcholine and biogenic amine levels in rat cortex. Neuropharmacology, 35, 205-211.
    • (1996) Neuropharmacology , vol.35 , pp. 205-211
    • Giacobini, E.1    Zhu, X.D.2    Williams, E.3    Sherman, K.A.4
  • 14
    • 0025634268 scopus 로고
    • Neurochemical aspects on aging and diseases with cognitive impairment
    • GOTTFRIES, C.G. (1990). Neurochemical aspects on aging and diseases with cognitive impairment. J. Neurosci. Res., 27, 541-547.
    • (1990) J. Neurosci. Res. , vol.27 , pp. 541-547
    • Gottfries, C.G.1
  • 15
    • 2442453242 scopus 로고    scopus 로고
    • Comparison of the effect of TAK-147 (Zanapezil) and E-2020 (Donepezil) on extracellular acetylcholine level and blood flow in the ventral hippocampus of freely moving rats
    • HATIP-AL-KHATIB, I., ARAI, T., EGASHIRA, N., IWASAKI, K. & FUJIWARA, M. (2004). Comparison of the effect of TAK-147 (Zanapezil) and E-2020 (Donepezil) on extracellular acetylcholine level and blood flow in the ventral hippocampus of freely moving rats. Brain Res., 1012, 169-176.
    • (2004) Brain Res. , vol.1012 , pp. 169-176
    • Hatip-Al-Khatib, I.1    Arai, T.2    Egashira, N.3    Iwasaki, K.4    Fujiwara, M.5
  • 16
    • 0345276539 scopus 로고    scopus 로고
    • Effects of donepezil on DOI-induced head twitch response in mice: Implications for Tourette syndrome
    • HAYSLETT, R.L. & TIZABI, Y. (2003). Effects of donepezil on DOI-induced head twitch response in mice: implications for Tourette syndrome. Pharmacol. Biochem. Behav., 76, 409-415.
    • (2003) Pharmacol. Biochem. Behav. , vol.76 , pp. 409-415
    • Hayslett, R.L.1    Tizabi, Y.2
  • 18
    • 0037846457 scopus 로고    scopus 로고
    • Acetylcholine enhancement in the nucleus accumbens prevents addictive behaviors of cocaine and morphine
    • HIKIDA, T., KITABATAKE, Y., PASTAN, I. & NAKANISHI, S. (2003). Acetylcholine enhancement in the nucleus accumbens prevents addictive behaviors of cocaine and morphine. Proc. Natl. Acad. Sci. U.S.A., 100, 6169-6173.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 6169-6173
    • Hikida, T.1    Kitabatake, Y.2    Pastan, I.3    Nakanishi, S.4
  • 19
    • 0030973899 scopus 로고    scopus 로고
    • Neurochemical effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5- tetrahydro-1H-1-benzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor in rats
    • HIRAI, K., KATO, K., NAKAYAMA, T., HAYAKO, H., ISHIHARA, Y., GOTO, G. & MIYAMOTO, M. (1997). Neurochemical effects of 3-[1-(phenylmethyl)-4- piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor in rats. J. Pharmacol. Exp. Ther., 280, 1261-1269.
    • (1997) J. Pharmacol. Exp. Ther. , vol.280 , pp. 1261-1269
    • Hirai, K.1    Kato, K.2    Nakayama, T.3    Hayako, H.4    Ishihara, Y.5    Goto, G.6    Miyamoto, M.7
  • 21
    • 0034121289 scopus 로고    scopus 로고
    • Central selective acetylcholinesterase inhibitor with neurotrophic activity: Structure-activity relationships of TAK-147 and related compounds
    • ISHIHARA, Y., GOTO, G. & MIYAMOTO, M. (2000). Central selective acetylcholinesterase inhibitor with neurotrophic activity: structure-activity relationships of TAK-147 and related compounds. Curr. Med. Chem., 7, 341-354.
    • (2000) Curr. Med. Chem. , vol.7 , pp. 341-354
    • Ishihara, Y.1    Goto, G.2    Miyamoto, M.3
  • 22
    • 0036120957 scopus 로고    scopus 로고
    • Effects of T-82, a new quinoline derivative, on cholinesterase activity and extracellular acetylcholine concentration in rat brain
    • ISOMA, K., ISHIKAWA, M., OHTA, M., OGAWA, Y., HASEGAWA, H., KOHDA, T. & KAMEI, J. (2002). Effects of T-82, a new quinoline derivative, on cholinesterase activity and extracellular acetylcholine concentration in rat brain. Jpn. J. Pharmacol., 88, 206-212.
    • (2002) Jpn. J. Pharmacol. , vol.88 , pp. 206-212
    • Isoma, K.1    Ishikawa, M.2    Ohta, M.3    Ogawa, Y.4    Hasegawa, H.5    Kohda, T.6    Kamei, J.7
  • 23
    • 0033593489 scopus 로고    scopus 로고
    • TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons
    • KATO, K., HAYAKO, H., ISHIHARA, H., MARUI, Y., IWANE, M. & MIYAMOTO, M. (1999). TAK-147, an acetylcholinesterase inhibitor, increases choline acetyltransferase activity in cultured rat septal cholinergic neurons. Neurosci. Lett., 260, 5-8.
    • (1999) Neurosci. Lett. , vol.260 , pp. 5-8
    • Kato, K.1    Hayako, H.2    Ishihara, H.3    Marui, Y.4    Iwane, M.5    Miyamoto, M.6
  • 24
    • 0033580044 scopus 로고    scopus 로고
    • Effect of neostigmine on the hippocampal noradrenaline release: Role of cholinergic receptors
    • KISS, J.P., VIZI, E.S. & WESTERINK, B.H. (1999). Effect of neostigmine on the hippocampal noradrenaline release: role of cholinergic receptors. Neuroreport, 10, 81-86.
    • (1999) Neuroreport , vol.10 , pp. 81-86
    • Kiss, J.P.1    Vizi, E.S.2    Westerink, B.H.3
  • 25
    • 0042731701 scopus 로고    scopus 로고
    • Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons
    • KLOTZ, L., SASTRE, M., KREUTZ, A., GAVRILYUK, V., KLOCKGETHER, T., FEINSTEIN, D.L. & HENEKA, M.T. (2003). Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J. Neurochem., 86, 907-916.
    • (2003) J. Neurochem. , vol.86 , pp. 907-916
    • Klotz, L.1    Sastre, M.2    Kreutz, A.3    Gavrilyuk, V.4    Klockgether, T.5    Feinstein, D.L.6    Heneka, M.T.7
  • 26
    • 0034681325 scopus 로고    scopus 로고
    • Inhibitory effect of orally administered donepezil hydrochloride (E2020), a novel treatment for Alzheimer's disease, on cholinesterase activity in rats
    • KOSASA, T., KURIYA, Y., MATSUI, K. & YAMANISHI, Y. (2000). Inhibitory effect of orally administered donepezil hydrochloride (E2020), a novel treatment for Alzheimer's disease, on cholinesterase activity in rats. Eur. J. Pharmacol., 389, 173-179.
    • (2000) Eur. J. Pharmacol. , vol.389 , pp. 173-179
    • Kosasa, T.1    Kuriya, Y.2    Matsui, K.3    Yamanishi, Y.4
  • 27
    • 0028085634 scopus 로고
    • Monoamine vesicular uptake sites in patients with Parkinson's disease and Alzheimer's disease, as measured by tritiated dihydrotetrabenazine autoradiography
    • LEHERICY, S., BRANDEL, J.P., HIRSCH, E.C., ANGLADE, P., VILLARES, J., SCHERMAN, D., DUYCKAERTS, C., JAVOY-AGID, F. & AGID, Y. (1994). Monoamine vesicular uptake sites in patients with Parkinson's disease and Alzheimer's disease, as measured by tritiated dihydrotetrabenazine autoradiography. Brain Res., 659, 1-9.
    • (1994) Brain Res. , vol.659 , pp. 1-9
    • Lehericy, S.1    Brandel, J.P.2    Hirsch, E.C.3    Anglade, P.4    Villares, J.5    Scherman, D.6    Duyckaerts, C.7    Javoy-Agid, F.8    Agid, Y.9
  • 28
    • 0025909805 scopus 로고
    • Monoamines and related metabolite levels in the cerebrospinal fluid of patients with dementia of Alzheimer type. Influence of treatment with L-deprenyl
    • MARTIGNONI, E., BONO, G., BLANDINI, F., SINFORIANI, E., MERLO, P. & NAPPI, G. (1991). Monoamines and related metabolite levels in the cerebrospinal fluid of patients with dementia of Alzheimer type. Influence of treatment with L-deprenyl. J. Neural Transm-Park., 3, 15-25.
    • (1991) J. Neural Transm-Park. , vol.3 , pp. 15-25
    • Martignoni, E.1    Bono, G.2    Blandini, F.3    Sinforiani, E.4    Merlo, P.5    Nappi, G.6
  • 29
    • 0037216484 scopus 로고    scopus 로고
    • Acetylcholinesterase inhibitor (donepezil hydrochloride) reduces heart rate variability
    • MASUDA, Y. & KAWAMURA, A. (2003). Acetylcholinesterase inhibitor (donepezil hydrochloride) reduces heart rate variability. J. Cardiovasc. Pharmacol., 41 (Suppl 1), S67-S71.
    • (2003) J. Cardiovasc. Pharmacol. , vol.41 , Issue.SUPPL. 1
    • Masuda, Y.1    Kawamura, A.2
  • 31
    • 0037310558 scopus 로고    scopus 로고
    • Selective 5-HT1A antagonists WAY 100635 and NAD-299 attenuate the impairment of passive avoidance caused by scopolamine in the rat
    • MISANE, I. & OGREN, S.O. (2003). Selective 5-HT1A antagonists WAY 100635 and NAD-299 attenuate the impairment of passive avoidance caused by scopolamine in the rat. Neuropsychopharmacology, 28, 253-264.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 253-264
    • Misane, I.1    Ogren, S.O.2
  • 32
    • 0030426815 scopus 로고    scopus 로고
    • Effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1-H- 1-benzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor, on impaired learning and memory in animal models
    • MIYAMOTO, M., TAKAHASHI, H., KATO, K., HIRAI, K., ISHIHARA, Y. & GOTO, G. (1996). Effects of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5- tetrahydro-1-H-1-benzazepin-8-yl)-1-propanone fumarate (TAK-147), a novel acetylcholinesterase inhibitor, on impaired learning and memory in animal models. J. Pharmacol. Exp. Ther., 277, 1292-1304.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1292-1304
    • Miyamoto, M.1    Takahashi, H.2    Kato, K.3    Hirai, K.4    Ishihara, Y.5    Goto, G.6
  • 33
    • 0038167792 scopus 로고    scopus 로고
    • The effect of Aricept in persons with persistent memory disorder following traumatic brain injury: A pilot study
    • MOREY, C.E., CILO, M., BERRY, J. & CUSICK, C. (2003). The effect of Aricept in persons with persistent memory disorder following traumatic brain injury: a pilot study. Brain Injury, 17, 809-815.
    • (2003) Brain Injury , vol.17 , pp. 809-815
    • Morey, C.E.1    Cilo, M.2    Berry, J.3    Cusick, C.4
  • 34
    • 0030294475 scopus 로고    scopus 로고
    • Effect of TAK-147, a novel AChE inhibitor, on cerebral energy metabolism
    • NAKAYAMA, T., TAKAHASHI, H., MIYAMOTO, M., GOTO, G. & NAGAI, Y. (1996). Effect of TAK-147, a novel AChE inhibitor, on cerebral energy metabolism. Neurobiol. Aging, 17, 849-857.
    • (1996) Neurobiol. Aging , vol.17 , pp. 849-857
    • Nakayama, T.1    Takahashi, H.2    Miyamoto, M.3    Goto, G.4    Nagai, Y.5
  • 36
    • 0034467344 scopus 로고    scopus 로고
    • Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro
    • OGURA, H., KOSASA, T., KURIYA, Y. & YAMANISHI, Y. (2000). Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find. Exp. Clin. Pharmacol., 22, 609-613.
    • (2000) Methods Find. Exp. Clin. Pharmacol. , vol.22 , pp. 609-613
    • Ogura, H.1    Kosasa, T.2    Kuriya, Y.3    Yamanishi, Y.4
  • 37
    • 0035896244 scopus 로고    scopus 로고
    • Central and peripheral activity of cholinesterase inhibitors as revealed by yawning and fasciculation in rats
    • OGURA, H., KOSASA, T., KURIYA, Y. & YAMANISHI, Y. (2001). Central and peripheral activity of cholinesterase inhibitors as revealed by yawning and fasciculation in rats. Eur. J. Pharmacol., 415, 157-164.
    • (2001) Eur. J. Pharmacol. , vol.415 , pp. 157-164
    • Ogura, H.1    Kosasa, T.2    Kuriya, Y.3    Yamanishi, Y.4
  • 38
    • 0032004958 scopus 로고    scopus 로고
    • Changes of monoamines in post-mortem brains from patients with diffuse Lewy body disease
    • OHARA, K., KONDO, N. & OHARA, K. (1998). Changes of monoamines in post-mortem brains from patients with diffuse Lewy body disease. Prog. Neuropsychopharmacol. Biol. Psychiatry, 22, 311-317.
    • (1998) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.22 , pp. 311-317
    • Ohara, K.1    Kondo, N.2    Ohara, K.3
  • 42
    • 0346504010 scopus 로고    scopus 로고
    • Effects of donepezil treatment on rat nicotinic acetylcholine receptor levels in vivo and in vitro
    • REID, R.T. & SABBAGH, M.N. (2003). Effects of donepezil treatment on rat nicotinic acetylcholine receptor levels in vivo and in vitro. J. Alzheimer's Dis., 5, 429-436.
    • (2003) J. Alzheimer's Dis. , vol.5 , pp. 429-436
    • Reid, R.T.1    Sabbagh, M.N.2
  • 43
    • 0034740154 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonists enhance retention of a water maze task in the rat
    • ROGERS, D.C. & HAGAN, J.J. (2001). 5-HT6 receptor antagonists enhance retention of a water maze task in the rat. Psychopharmacology (Berlin), 158, 114-119.
    • (2001) Psychopharmacology (Berlin) , vol.158 , pp. 114-119
    • Rogers, D.C.1    Hagan, J.J.2
  • 44
    • 0036315675 scopus 로고    scopus 로고
    • Effect of subchronic administration of metrifonate, rivastigmine and donepezil on brain acetylcholine in aged F344 rats
    • SCALI, C., CASAMENTI, F., BELLUCCI, A., COSTAGLI, C., SCHMIDT, B. & PEPEU, G. (2002). Effect of subchronic administration of metrifonate, rivastigmine and donepezil on brain acetylcholine in aged F344 rats. J. Neural Transm., 109, 1067-1080.
    • (2002) J. Neural Transm. , vol.109 , pp. 1067-1080
    • Scali, C.1    Casamenti, F.2    Bellucci, A.3    Costagli, C.4    Schmidt, B.5    Pepeu, G.6
  • 45
    • 3442876461 scopus 로고    scopus 로고
    • Psychiatric aspects of Parkinson's disease-an update
    • SCHRAG, A. (2004). Psychiatric aspects of Parkinson's disease-an update. J. Neurol. 251, 795-804.
    • (2004) J. Neurol. , vol.251 , pp. 795-804
    • Schrag, A.1
  • 46
    • 0036431607 scopus 로고    scopus 로고
    • A new area in the human brain associated with learning and memory: Immunohistochemical and functional MRI analysis
    • SHU, S.Y., WU, Y.M., BAO, X.M., WEN, Z.B., HUANG, F.H., LI, S.X., FU, Q.Z. & NING, Q. (2002). A new area in the human brain associated with learning and memory: immunohistochemical and functional MRI analysis. Mol. Psychiatry, 7, 1018-1022.
    • (2002) Mol. Psychiatry , vol.7 , pp. 1018-1022
    • Shu, S.Y.1    Wu, Y.M.2    Bao, X.M.3    Wen, Z.B.4    Huang, F.H.5    Li, S.X.6    Fu, Q.Z.7    Ning, Q.8
  • 47
    • 18544412891 scopus 로고    scopus 로고
    • Decreased monoamine metabolites in frontotemporal dementia and Alzheimer's disease
    • SJOGREN, M., MINTHON, L., PASSANT, U., BLENNOW, K. & WALLIN, A. (1998). Decreased monoamine metabolites in frontotemporal dementia and Alzheimer's disease. Neurobiol. Aging, 19, 379-384.
    • (1998) Neurobiol. Aging , vol.19 , pp. 379-384
    • Sjogren, M.1    Minthon, L.2    Passant, U.3    Blennow, K.4    Wallin, A.5
  • 48
    • 0141732801 scopus 로고    scopus 로고
    • Non-stimulant treatment for attention-deficit/hyperactivity disorder
    • SPENCER, T. & BIEDERMAN, J. (2002). Non-stimulant treatment for attention-deficit/hyperactivity disorder. J. Atten. Disord., 6 (Suppl 1), S109-S119.
    • (2002) J. Atten. Disord. , vol.6 , Issue.SUPPL. 1
    • Spencer, T.1    Biederman, J.2
  • 54
    • 0037020523 scopus 로고    scopus 로고
    • Effect of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1- benzazepin-8-yl)-1-propanone fumarate, a novel acetylcholinesterase inhibitor, on spatial cognitive impairment induced by chronic cerebral hypoperfusion in rats
    • XU, A., CHEN, Z., YANAI, K., HUANG, Y. & WEI, E. (2002). Effect of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl) -1-propanone fumarate, a novel acetylcholinesterase inhibitor, on spatial cognitive impairment induced by chronic cerebral hypoperfusion in rats. Neurosci. Lett., 331, 33-36.
    • (2002) Neurosci. Lett. , vol.331 , pp. 33-36
    • Xu, A.1    Chen, Z.2    Yanai, K.3    Huang, Y.4    Wei, E.5
  • 55
    • 0035108489 scopus 로고    scopus 로고
    • Frontotemporal dementia: Evidence for impairment of ascending serotoninergic but not noradrenergic innervation. Immunocytochemical and quantitative study using a graph method
    • YANG, Y. & SCHMITT, H.P. (2001). Frontotemporal dementia: evidence for impairment of ascending serotoninergic but not noradrenergic innervation. Immunocytochemical and quantitative study using a graph method. Acta Neuropathol. (Berlin), 101, 256-270.
    • (2001) Acta Neuropathol. (Berlin) , vol.101 , pp. 256-270
    • Yang, Y.1    Schmitt, H.P.2
  • 56
    • 4944239612 scopus 로고    scopus 로고
    • Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release
    • ZHANG, L., ZHOU, F.M. & DANI, J.A. (2004). Cholinergic drugs for Alzheimer's disease enhance in vitro dopamine release. Mol. Pharmacol., 66, 538-544.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 538-544
    • Zhang, L.1    Zhou, F.M.2    Dani, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.