Astragaloside IV attenuates Toll-like receptor 4 expression via NF-κB pathway under high glucose condition in mesenchymal stem cells

European Journal of Pharmacology

Volumn 696, Issue 1-3, 2012, Pages 203-209

  Li, Mincai ^a   Yu, Liangzu ^a   She, Tonghui ^a   Gan, Yapin ^a   Liu, Fuxin ^a   Hu, Zhengwu ^a   Chen, Yongbin ^a   Li, Suqin ^a   Xia, Hongli ^b  

^a HUBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Central Hospital of Xianning   (China)

Author keywords

Astragaloside IV; Bone mesenchymal stem cell; Diabetes; NF B pathway; Toll like receptor 4

Indexed keywords

ASTRAGALOSIDE IV; GELATINASE A; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIDIABETIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE; GENE EXPRESSION REGULATION; HUMAN; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TLR4 GENE; WESTERN BLOTTING;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINE CCL2; DIABETES MELLITUS, TYPE 1; DRUGS, CHINESE HERBAL; GLUCOSE; HUMANS; MATRIX METALLOPROTEINASE 2; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; RNA, MESSENGER; SAPONINS; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84869089081     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.09.033     Document Type: Article

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