Wy14643 improves vascular function in the aorta of the spontaneously hypertensive rat mainly by activating peroxisome proliferator-activated receptors alpha

European Journal of Pharmacology

Volumn 696, Issue 1-3, 2012, Pages 101-110

  Qu, Chen ^a,c   Leung, Susan W S ^a   Vanhoutte, Paul M ^a,b   Man, Ricky Y K ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b Chonbuk National University   (South Korea)

^c SHENYANG MEDICAL COLLEGE   (China)

Author keywords

Endothelial dysfunction; Endothelium derived contracting factor; Nitric oxide; Peroxisome proliferator activated receptor agonist; Prostaglandin

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 2 CHLORO 5 NITROBENZANILIDE; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FENOFIBRATE; N(G) NITROARGININE METHYL ESTER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; ROSIGLITAZONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFICACY; DRUG POTENTIATION; DRUG STRUCTURE; ENDOTHELIUM; ENZYME ACTIVATION; HEART FUNCTION; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; TREATMENT RESPONSE; WESTERN BLOTTING;

ANIMALS; AORTA, THORACIC; FENOFIBRATE; HYPERTENSION; MALE; PEROXISOME PROLIFERATORS; PPAR ALPHA; PPAR GAMMA; PYRIMIDINES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; THIAZOLIDINEDIONES; VASOCONSTRICTION;

EID: 84869083545     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.09.015     Document Type: Article

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