Innovative use of a bacterial enzyme involved in sialic acid degradation to initiate sialic acid biosynthesis in glycoengineered insect cells

Metabolic Engineering

Volumn 14, Issue 6, 2012, Pages 642-652

  Geisler, Christoph ^a   Jarvis, Donald L ^a  

^a UNIVERSITY OF WYOMING   (United States)

Author keywords

Baculovirus; Epimerase; Glycoengineering; Glycoprotein production; Insect cells; Sialylation

Indexed keywords

BACULOVIRUS; EPIMERASE; GLYCOENGINEERING; INSECT CELLS; SIALYLATION;

BIOSYNTHESIS; CARBOXYLIC ACIDS; CELLS; ENZYMES; ESCHERICHIA COLI; GENES; GLYCOPROTEINS; GLYCOSYLATION; MAMMALS; PRODUCTION PLATFORMS; RECOMBINANT PROTEINS;

CYTOLOGY;

EPIMERASE; GLYCOPROTEIN; MANNOSAMINE; N ACETYLGLUCOSAMINE 6 PHOSPHATE 2' EPIMERASE; N ACETYLMANNOSAMINE; SIALIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BACULOVIRUS; BIOSYNTHESIS; CELL ISOLATION; CELL SURFACE; CONTROLLED STUDY; ESCHERICHIA COLI; GLYCOSYLATION; INSECT CELL; MICROBIAL DEGRADATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN EXPRESSION; SIALYLATION;

ANIMALS; CARBOHYDRATE EPIMERASES; CELLS, CULTURED; CHROMOSOMES, INSECT; ESCHERICHIA COLI; GENETIC ENHANCEMENT; N-ACETYLNEURAMINIC ACID; SF9 CELLS; SPODOPTERA; TRANSFECTION;

BACTERIA (MICROORGANISMS); EUKARYOTA; HEXAPODA; MAMMALIA;

EID: 84869069039     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2012.08.005     Document Type: Article

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