The triterpenoid pristimerin induces U87 glioma cell apoptosis through reactive oxygen species-mediated mitochondrial dysfunction

Oncology Letters

Volumn 5, Issue 1, 2012, Pages 242-248

  Yan, Yan Yan ^a   Bai, Jian Ping ^a   Xie, Yong ^a   Yu, Jie Zhong ^a   Ma, Cun Gen ^a  

^a SHANXI DATONG UNIVERSITY   (China)

Author keywords

Apoptosis; Glioma; Pristimerin; Reactive oxygen species; U87 cells

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 3; CASPASE 9; CYTOCHROME C; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PRISTIMERIN; PROTEIN BAX; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG POTENCY; GLIOMA CELL; HUMAN; HUMAN CELL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

EID: 84869064169     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.982     Document Type: Article

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