Autophagy influences maternal mRNA degradation and apoptosis in porcine parthenotes developing in vitro

Journal of Reproduction and Development

Volumn 58, Issue 5, 2012, Pages 576-584

  Xu, Yong Nan ^a   Shen, Xing Hui ^b   Lee, Seung Eun ^a   Kwon, Jung Suk ^a   Kim, Deuk Joong ^a   Heo, Young Tae ^a   Cui, Xiang Shun ^a   Kim, Nam Hyung ^a  

^a Chungbuk National University   (South Korea)

^b HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

3 MA; Apoptosis; Autophagy; LC3; Maternal gene; Rapamycin

Indexed keywords

3 METHYLADENINE; 3-METHYLADENINE; ADENINE; APOPTOSIS REGULATORY PROTEIN; CELL CYCLE PROTEIN; DRUG DERIVATIVE; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN; RAPAMYCIN; TRANSCRIPTION FACTOR;

ANIMAL; APOPTOSIS; ARTICLE; AUTOPHAGY; BLASTOCYST; CYTOLOGY; DRUG EFFECT; ECTOGENESIS; FEMALE; GENE EXPRESSION REGULATION; GENETICS; IN VITRO OOCYTE MATURATION; MEIOSIS; METABOLISM; OOCYTE; PARTHENOGENESIS; RNA STABILITY; SWINE;

ADENINE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BLASTOCYST; CELL CYCLE PROTEINS; ECTOGENESIS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN VITRO OOCYTE MATURATION TECHNIQUES; MEIOSIS; MICROTUBULE-ASSOCIATED PROTEINS; OOCYTES; PARTHENOGENESIS; RNA STABILITY; RNA, MESSENGER, STORED; SIROLIMUS; SUS SCROFA; TRANSCRIPTION FACTORS;

SUIDAE; SUS;

EID: 84869050680     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.2012-005     Document Type: Article

References (50)

1. Klionsky DJ. The molecular machinery of autophagy: Unanswered questions. J Cell Sci 2005; 118: 7-8. [Medline] [CrossRef]
2. Levine B, Klionsky DJ. Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Dev Cell 2004; 6: 463-477. [Medline] [CrossRef]
3. Mizushima N, Ohsumi Y, Yoshimori T. Autophagosome formation in mammalian cells. Cell Struct Funct 2002; 27: 421-429. [Medline] [CrossRef]
4. Tsukamoto S, Kuma A, Murakami M, Kishi C, Yamamoto A, Mizushima N. Autophagy is essential for preimplantation development of mouse embryos. Science 2008; 321: 117-120. [Medline] [CrossRef]
5. Xu YN, Cui XS, Sun SC, Lee SE, Li YH, Kwon JS, Lee SH, Hwang KC, Kim NH. Mitochondrial dysfunction influences apoptosis and autophagy in porcine parthenotes developing in vitro. J Reprod Dev 2011; 57: 143-150. [Medline] [CrossRef]
6. Merz EA, Brinster RL, Brunner S, Chen HY. Protein degradation during preimplantation development of the mouse. J Reprod Fertil 1981; 61: 415-418. [Medline] [CrossRef]
7. DeRenzo C, Seydoux G. A clean start: degradation of maternal proteins at the oocyte-toembryo transition. Trends Cell Biol 2004; 14: 420-426. [Medline] [CrossRef]
8. Stitzel ML, Seydoux G. Regulation of the oocytes-to-zygote transition. Science 2007; 316: 407-408. [Medline] [CrossRef]
9. Yu L, Alva A, Su H, Dutt P, Freundt E, Welsh S, Baehrecke EH, Lenardo MJ. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304: 1500-1502. [Medline] [CrossRef]
10. Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N, Packer M, Schneider MD, Levine B. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122: 927-939. [Medline] [CrossRef]
11. Suzuki K, Ohsumi Y. Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae. FEBS Lett 2007; 581: 2156-2161. [Medline] [CrossRef]
12. Xie Z, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9: 1102-1109. [Medline] [CrossRef]
13. Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P. Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 2000; 275: 992-998. [Medline] [CrossRef]
14. Kihara A, Noda T, Ishihara N, Ohsumi Y. Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae. J Cell Biol 2001; 152: 519-530. [Medline] [CrossRef]
15. Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 2005; 6: 505-510. [Medline] [CrossRef]
16. Kirisako T, Ichimura Y, Okada H, Kabeya Y, Mizushima N, Yoshimori T, Ohsumi M, Takao T, Noda T, Ohsumi Y. The reversible modification regulates the membranebinding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 2000; 151: 263-276. [Medline] [CrossRef]
17. Noda T, Kim J, Huang WP, Baba M, Tokunaga C, Ohsumi Y, Klionsky DJ. Apg9p/ Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. J Cell Biol 2000; 148: 465-480. [Medline] [CrossRef]
18. Fortunato F, Bürgers H, Bergmann F, Rieger P, Büchler MW, Kroemer G, Werner J. Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis. Gastroenterology 2009; 137: 350-360. e5. [Medline] [CrossRef]
19. Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E, Ohsumi Y, Yoshimori T. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19: 5720-5728. [Medline] [CrossRef]
20. Mann SS, Hammarback JA. Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B. J Biol Chem 1994; 269: 11492-11497. [Medline]
21. Kirisako T, Baba M, Ishihara N, Miyazawa K, Ohsumi M, Yoshimori T, Noda T, Ohsumi Y. Formation process of autophagosome is traced with Apg8/Aut7p in yeast. J Cell Biol 1999; 147: 435-446. [Medline] [CrossRef]
22. He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet 2009; 43: 67-93. [Medline] [CrossRef]
23. Schwartz LM, Smith SW, Jones ME, Osborne BA. Do all programmed cell deaths occur via apoptosis? Proc Natl Acad Sci 1993; 90: 980-984. [Medline] [CrossRef]
24. Li J, Hou N, Faried A, Tsutsumi S, Takeuchi T, Kuwano H. Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells. Ann Surg Oncol 2009; 16: 761-771. [Medline] [CrossRef]
25. Choi J, Jo M, Lee E, Choi D. The role autophagy in corpus luteum regression in the rat. Biol Reprod 2011; 85: 465-472. [Medline] [CrossRef]
26. Pan T, Rawal P, Wu Y, Xie W, Jankovic J, Le W. Rapamycin protects against rotenoneinduced apoptosis through autophagy induction. Neuroscience 2009; 164: 541-551. [Medline] [CrossRef]
27. Tirado OM, Mateo-Lozano S, Notario V. Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax:Bcl-xl ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity. Oncogene 2005; 24: 3348-3357. [Medline] [CrossRef]
28. Schöler HR, Dressler GR, Balling R, Rohdewohld H, Gruss P. Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J 1990; 9: 2185-2195. [Medline]
29. Schöler HR, Ciesiolka T, Gruss P. A nexus between Oct-4 and E1A: implications for gene regulation in embryonic stem cells. Cell 1991; 66: 291-304. [Medline] [CrossRef]
30. Ryan AK, Rosenfeld MG. POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev 1997; 11: 1207-1225. [Medline] [CrossRef]
31. Rosner MH, Vigano MA, Ozato K, Timmons PM, Poirier F, Rigby PW, Staudt LM. A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 1990; 345: 686-692. [Medline] [CrossRef]
32. Nichols J, Zevnik B, Anastassiadis K, Niwa H, Klewe-Nebenius D, Chambers I, Scholer H, Smith A. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998; 95: 379-391. [Medline] [CrossRef]
33. Niwa H, Masui S, Chambers I, Smith AG, Miyazaki J. Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of Oct-3/4 in embryonic stem cells. Mol Cell Biol 2002; 22: 1526-1536. [Medline] [Cross-Ref]
34. Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S, Smith A. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003; 113: 643-655. [Medline] [CrossRef]
35. Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113: 631-642. [Medline] [CrossRef]
36. Im GS, Lai L, Liu Z, Hao Y, Wax D, Bonk A, Prather RS. In vitro development of preimplantation porcine nuclear transfer embryos cultured in different media and gas atmospheres. Theriogenology 2004; 61: 1125-1135. [Medline] [CrossRef]
37. Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 2004; 313: 453-458. [Medline] [CrossRef]
38. Van Thuan N, Harayama H, Miyake M. Characteristics of preimplantational development of porcine parthenogenetic diploids relative to the existence of amino acids in vitro. Biol Reprod 2002; 67: 1688-1698. [Medline] [CrossRef]
39. Cui XS, Kim NH. Epidermal growth factor induces Bcl-xL gene expression and reduces apoptosis in porcine parthenotes developing in vitro. Mol Reprod Dev 2003; 66: 273-278. [Medline] [CrossRef]
40. Lee JW, Tian XC, Yang X. Optimization of parthenogenetic activation protocol in porcine. Mol Reprod Dev 2004; 68: 51-57. [Medline] [CrossRef]
41. Anderson JE, Matteri RL, Abeydeera LR, Day BN, Prather RS. Degradation of maternal cdc25c during the maternal to zygotic transition is dependent upon embryonic transcription. Mol Reprod Dev 2001; 60: 181-188. [Medline] [CrossRef]
42. Hendil KB, Lauridsen AM, Seqlen PO. Both endocytic and endogenous protein degradation in fibroblasts is stimulated by serum/amino acid deprivation and inhibited by 3-methyladenine. Biochem J 1990; 272: 577-581. [Medline]
43. Balgi AD, Fonseca BD, Donohue E, Tsang TC, Lajoie P, Proud CG, Nabi IR, Roberge M. Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling. PLoS One 2009; 4: e7124. [Medline] [CrossRef]
44. Ren Y, Huang F, Liu Y, Yang Y, Jiang Q, Xu C. Autopahgy inhibition through PI3K/ Akt increases apoptosis by sodium selenite in NB4 cells. BMB Rep 2009; 42: 599-604. [Medline] [CrossRef]
45. Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, Brunner T, Simon HU. Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 2006; 8: 1124-1132. [Medline] [CrossRef]
46. Luo S, Rubinsztein DC. Atg5 and Bcl-2 provide novel insights into the interplay between apoptosis and autophagy. Cell Death Differ 2007; 14: 1247-1250. [Medline] [CrossRef]
47. Boise LH, Gonzales-Garcia M, Postema CE, Ding LA, Lindsten T, Turka L, Mao X, Nunez G, Thompson CB. Bcl-x, a bcl-2ralated gene that functions as a dominant regulator of apoptotic cell death. Cell 1993; 74: 597-608. [Medline] [CrossRef]
48. Kehler J, Tolkunova E, Koschorz B, Pesce M, Gentile L, Boiani M, Lomelí H, Nagy A, McLaughlin KJ, Schöler HR, Tomilin A. Oct4 is required for primordial germ cell survival. EMBO Rep 2004; 5: 1078-1083. [Medline] [CrossRef]
49. Yamaguchi S, Kurimoto K, Yabuta Y, Sasaki H, Nakatsuji N, Saitou M, Tada T. Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells. Development 2009; 136: 4011-4020. [Medline] [CrossRef]
50. Keramari M, Razavi J, Ingman KA, Patsch C, Edenhofer F, Ward CM, Kimber SJ. Sox2 is essential for formation of trophectoderm in the preimplantation embryo. PLoS One 2010; 5: e13952. [Medline] [CrossRef]