Downregulation of cold-inducible RNA-binding protein activates mitogen-activated protein kinases and impairs spermatogenic function in mouse testes

Asian Journal of Andrology

Volumn 14, Issue 6, 2012, Pages 884-889

  Xia, Zhi Ping ^a   Zheng, Xin Min ^a   Zheng, Hang ^a   Liu, Xiao Jun ^a   Liu, Gui Yong ^b   Wang, Xing Huan ^a  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b Qianjiang Central Hospital   (China)

Author keywords

cold inducible RNA binding protein (CIRP); heat stress; male infertility; mitogen activated protein kinase (MAPK); siRNA in vivo; spermatogenesis

Indexed keywords

COLD INDUCIBLE RNA BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RNA BINDING PROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION; GERM CELL; HEAT STRESS; IMMUNOHISTOCHEMISTRY; MALE; MALE INFERTILITY; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SEMINIFEROUS TUBULE; SPERMATOGENESIS; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; COLD TEMPERATURE; DOWN-REGULATION; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; SPERMATOGENESIS; TESTIS;

EID: 84869023727     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2012.71     Document Type: Article

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