Protective effects of melatonin on testicular torsion/detorsion-induced ischemia-reperfusion injury in rats

Experimental and Molecular Pathology

Volumn 89, Issue 3, 2010, Pages 314-320

  Kanter, M ^a  

^a TRAKYA UNIVERSITY   (Turkey)

Author keywords

Melatonin; PCNA; Testicular torsion; TUNEL; Ultrastructure

Indexed keywords

CYCLINE; MELATONIN; TESTOSTERONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DRUG EFFICACY; ELECTRON MICROSCOPY; HISTOPATHOLOGY; INTRACELLULAR SPACE; ISCHEMIA; MALE; MITOCHONDRIAL DNA DISORDER; NICK END LABELING; NONHUMAN; ORCHIECTOMY; RAT; REPERFUSION INJURY; SEMINIFEROUS TUBULE; SERTOLI CELL; SPERMATID; SPERMATOGENESIS; TESTIS; TESTIS INJURY; TESTIS ISCHEMIA; TESTIS TORSION; ULTRASTRUCTURE; WISTAR ALBINO GLAXO RAT;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MELATONIN; MICROSCOPY, ELECTRON, TRANSMISSION; RATS; RATS, WISTAR; REPERFUSION INJURY; SPERMATIC CORD TORSION; SPERMATOZOA;

ANIMALIA; RATTUS;

EID: 78249262577     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2010.07.006     Document Type: Article

References (42)

1. Akgur F.M., Kilinc K., Aktug T. Reperfusion injury after detorsion of unilateral testicular torsion. Urol. Res. 1993, 21:395-399.
2. Arendt J. Melatonin. Clin. Endocrinol. 1988, 29:205-229.
3. Baccetti B., Collodel G., Piomboni P. Apoptosis in human ejaculated sperm cells (notulae seminologicae 9). J. Submicrosc. Cytol. Pathol. 1996, 28:587-596.
4. Baker L.A., Turner T.T. Leydig cell function afterexperimental testicular torsion despite loss of spermatogenesis. J. Androl. 1995, 16:12-17.
5. Becker E.J., Turner T.T. Endocrine and exocrine effects of testicular torsion in the prepubertal and adult rat. J. Androl. 1995, 16:342-351.
6. Billig H., Furuta I., Rivie R.C., Tapanainen J., Parvinen M., Hsueh A.J. Apoptosis in testis germcells: developmental changes in gonadotropin dependence and localization to selective tubule stages. Endocrinology 1995, 136:5-12.
7. Celis J.E., Madsen P., Celis A., Nielsen H.V., Gesser B. Cyclin (PCNA, auxiliary protein of DNA polymerase delta) is a central component of the pathway(s) leading to DNA replication and cell division. FEBS. Lett. 1987, 220(1):1-7.
8. Dokmeci D., Inan M., Basaran U.N., Yalcin O., Aydogdu N., Turan F.N., Uz Y.H. Protective effect of L-carnitine on testicular ischemia-reperfusion injury in rats. Cell. Biochem. Funct. 2007, 25:611-618.
9. Dokmeci D., Kanter M., Inan M., Aydogdu N., Basaran U.N., Yalcin O., Turan F.N. Protective effects of ibuprofen on testicular torsion/detorsion-induced ischemia/reperfusion injury in rats. Arch. Toxicol. 2007, 81:655-663.
10. Fukuda S., Harada K., Kunimatsu M., Sakabe T., Yoshida K. Postischemic reperfusion induces a-fodrin proteolysis by m-calpain in the synaptosome and nucleus in rat brain. J. Neurochem. 1998, 70:2526-2532.
11. Hikim A.P.S., Wang C., Leung A., Swerdloff R.S. Involvement of apoptosis in the induction of germ cell degeneration in adult rats after gonadotropin-releasing hormone antagonist treatment. Endocrinology 1995, 136:2770-2775.
12. Hsu S.M., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 1981, 29:577-580.
13. Jarvis S., Elliott D.J., Morgan D., Winston R., Readhead C. Molecular markers for the assessment of postnatal male germ cell development in the mouse. Hum. Reprod. 2005, 20(1):108-116.
14. Jaskulski D., deRiel J.K., Mercer W.E., Calabretta B., Baserga R. Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA cyclin. Science 1988, 240(4858):1544-1546.
15. Johnsen S.G. Testicular biopsy score count - a method for registration of spermatogenesis in human testes. Normal values and results of 335 hypogonadal males. Hormones 1970, 1:2-25.
16. Kang M.J., Kim M.K., Terhune A., Park J.K., Kim Y.H., Koh G.Y. Cytoplasmic localization of cyclin D3 in seminiferous tubules during testicular development. Exp. Cell. Res. 1997, 234(1):27-36.
17. Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 1972, 26:239-257.
18. Kimura M., Itoh N., Takagi S., Sasao T., Takahashi A., Masumori N., Tsukamoto T. Balance of apoptosis and proliferation of germ cells related to spermatogenesis in aged men. J. Androl. 2003, 24(2):185-191.
19. Lysiak J.J., Nguyen Q.A., Turner T.T. Fluctuations in rat testicular interstitial oxygen tensions are linked to testicular vasomotion. Biol. Reprod. 2000, 63:1383-1389.
20. Lysiak J.J., Turner S.D., Nguyen Q.A., Singbartl K., Ley K., Turner T.T. Essential role of neutrophils in germ cell-specific apoptosis. Biol. Reprod. 2001, 65:718-725.
21. Lysiak J.J., Nguyen Q.A., Turner T.T. Peptide and nonpeptide reactive oxygen scavengers provide partial rescue of the testis after torsion. J. Androl. 2002, 23:400-409.
22. Lysiak J.J., Nguyen Q.A., Kirby J.L., Turner T.T. Ischemia-reperfusion of the murine testis stimulates the expression of proinflammatory cytokines and activation of c-jun N-terminal kinase in a pathway to E-selectin expression. Biol. Reprod. 2003, 69:202-210.
23. McCord J.M. Oxygen-derived free radicals in postischemic tissue injury. N. Engl. J. Med. 1985, 312:159-163.
24. Ohno M., Takemura G., Ohno A., Misao J., Hayakawa Y., Minatoguchi S., Fujiwara T., Fujiwara H. "Apoptotic" myocytes in infarct area in rabbit hearts may be oncotic myocytes with DNA fragmentation. Circulation 1998, 98:1422-1430.
25. Ozturk H., Buyukbayram H., Ozdemir E., Ketani A., Gurel A., Onen A., Otçu S. The effects of nitric oxide on the expression of cell adhesion molecules (ICAM-1, UEA-1, and tenascin) in rats with unilateral testicular torsion. J. Pediatr. Surg. 2003, 38:1621-1627.
26. Reiter R.J. The pineal gland and melatonin in relation to aging: a summary of the theories and of the data. Exp. Gerontol. 1995, 30:199-212.
27. Reiter R.J., Tan D.X., Osuna C., Gitto E. Actions of melatonin in the reduction of oxidative stress: a review. J. Biomed. Sci. 2000, 7:444-458.
28. Riedl S.J., Shi Y. Molecular mechanisms of caspase regulation during apoptosis. Nat. Rev. Mol. Cell Biol. 2004, 5(11):897-907.
29. Rodriguez C., Mayo J.C., Sainz R.M., Antolín I., Herrera F., Martín V., Reiter R.J. Regulation of antioxidant enzymes: a significant role for melatonin. J. Pineal Res. 2004, 36:1-9.
30. Saba M., Morales C.D., De Lamirdane E., Ganon C. Morphological and biochemical changes following acute unilateral testicular torsion in prepubertal rats. J. Urol. 1997, 157:1149-1154.
31. Said T.M., Paasch U., Glander H.J., Agarwal A. Role of caspases in male infertility. Hum. Reprod. Update 2004, 10(1):39-51.
32. Shiraishi K., Naito K., Yoshida K. Inhibition of calpain but not caspase protects the testis against injury after testicular torsion of rat. Biol. Reprod. 2000, 63:1538-1548.
33. Sinha Hikim A.P., Swerdloff R.S. Hormonal and genetic control of germ cell apoptosis in the testis. Rev. Reprod. 1999, 4:38-47.
34. Steger K., Aleithe I., Behre H., Bergmann M. The proliferation of spermatogonia in normal and pathological human seminiferous epithelium: an immunohistochemical study using monoclonal antibodies against Ki-67 protein and proliferating cell nuclear antigen. Mol. Hum. Reprod. 1998, 4(3):227-233.
35. Sukhotnik I., Miselevich I., Lurie M., Nativ O., Coran A.G., Mogilner G. The time relationship between ipsilateral testicular ischemia-reperfusion and germ cell apoptosis in the contralateral testis in rat. Pediatr. Surg. Int. 2005, 15:1-5.
36. Turner T.T. Acute experimental testicular torsion: no effect on contralateral testis. J. Androl. 1985, 6:65-72.
37. Turner T.T., Brown K.J. Spermatic cord torsion: loss of spermatogenesis despite return of blood flow. Biol. Reprod. 1993, 49:401-407.
38. Turner T.T., Tung K.S., Tomomasa H., Wilson L.W. Acute testicular ischemia results in germ cell-specific apoptosis in the rat. Biol. Reprod. 1997, 57:1267-1274.
39. Uguralp S., Bay Karabulut A., Mizrak B., Kaymaz F., Kiziltay A., Hasirci N. The effect of sustained and local administration of epidermal growth factor on improving bilateral testicular tissue after torsion. Urol. Res. 2004, 32:323-331.
40. Unsal A., Eroglu M., Avci A., Cimentepe E., Guven C., Derya Balbay M., Durak I. Protective role of natural antioxidant supplementation on testicular tissue after testicular torsion and detorsion. Scand. J. Urol. Nephrol. 2006, 40:17-22.
41. Weng S.L., Taylor S.L., Morshedi M., Schuffner A., Duran E.H., Beebe S., Oehninger S. Caspase activity and apoptotic markers in ejaculated human sperm. Mol. Hum. Reprod. 2002, 8:984-991.
42. Yoshida K., Inui M., Harada K., Saido T.C., Sorimachi Y., Ishihara T., Kawashima S., Sobue K. Reperfusion of rat heart after brief ischemia induces proteolysis of calspectin (non-erythroid spectrin or fodrin) by calpain. Circ. Res. 1995, 77:603-610.