Evidence for a role of mitogen-activated protein kinase 3/mitogen-activated protein kinase in the development of testicular ischemia-reperfusion injury

Biology of Reproduction

Volumn 73, Issue 4, 2005, Pages 730-736

  Minutoli, Letteria ^a,b   Antonuccio, Pietro ^a   Romeo, Carmelo ^a   Nicòtina, Piero Antonio ^a   Bitto, Alessandra ^a   Arena, Salvatore ^a   Polito, Francesca ^a   Altavilla, Domenica ^a   Turiaco, Nunzio ^a   Cutrupi, Antonio ^a   Zuccarello, Biagio ^a   Squadrito, Francesco ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

Kinases; Leydig cells; Male reproductive tract; Testis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HISTOPATHOLOGY; ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; TESTICULAR ISCHEMIA; TESTIS INJURY; TESTIS TORSION;

ANIMALS; DISEASE MODELS, ANIMAL; EDEMA; ENZYME INHIBITORS; FLAVONOIDS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TESTICULAR DISEASES; TESTIS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 25144482283     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.105.040741     Document Type: Article

References (30)

1. Williamson RNC. The continuing conundrum of testicular torsion. Br J Surg 1985; 72:509-510.
2. Turner TT, Brown KJ. Spermatic cord torsion: loss of spermatogenesis despite return blood flow. Biol Reprod 1993; 49:401-407.
3. Visser AJ, Heyns CF. Testicular function after torsion of the spermatic cord. BJU Int 2003; 92:200-203.
4. Kolettis PN, Stowe NT, Inman SR, Thomas AJ. Acute spermatic cord torsion alters the microcirculation of the contralateral testis. J Urol 1996; 155:350-354.
5. Zini A, Abitbol J, Girardi SK, Shulsinger D, Goldstein M, Schlegel PN. Germ cell apoptosis and endothelial nitric oxide synthase (eNOS) expression following ischemia-reperfusion injury to testis. Arch Androl 1998; 41:57-65.
6. Seger R, Krebs EG. The MAPK signaling cascade. FASEB J 1995; 9:726-735.
7. Davis RJ. MAPKs: New JNK expands the group. Trends Biochem Sci 1994; 19:470-473.
8. Widmann C, Gibson S, Jarpe MB, Johnson GL. Mitogen-activated protein kinases: conservation of a three kinase module from yeast to human. Physiol Rev 1999; 79:143-180.
9. Lysiak JJ, Nuyen QAT, Kirby JL, Turner TT. Ischemia-reperfusion of the murine testis stimulates the expression of proinflammatory cytokines and activation of c-jun N-terminal kinase in a pathways to E-selectin expression. Biol Reprod 2003; 69:202-210.
10. Fiers W. Tumor necrosis factor. Characterization at the molecular, cellular, and in vivo level. FEBS Lett 1991; 285:199-212.
11. Beutler B. TNF, immunity, and inflammatory disease: lessons of the past decade. J Invest Med 1995; 43:227-235.
12. Baker SJ, Reddy EP. Modulation of life and death by the TNF-receptor superfamily. Oncogene 1998; 17:3261-3270.
13. Lysiak JJ. The role of tumor necrosis factor-α and interleukin-I in the mammalian testis and their involvement in testicular torsion and autoimmune orchitis. Reprod Biol Endocrinol 2004; 2:1-10.
14. Hausenloy DJ, Yellon DM. New directions for protecting the heart against ischemia-reperfusion injury: targeting the reperfusion injury salvage kinase (RISK) pathway. Cardiovasc Res 2004; 61:448-460.
15. Ozkan KU, Boran C, Kilinc M, Garipardic M, Kurutas EB. The effect of zinc aspartate pretreatment on ischemia-reperfusion injury and early changes of blood and tissue antioxidant enzyme activities after unilateral testicular torsion-detorsion. J Pediatr Surg 2004; 39:91-95.
16. Saba M, Morales CR, Lamirande E, Gagnon C. Morphological and biochemical changes following acute unilateral testicular torsion in prepubertal rats. J Urol 1997; 157:1149-1154.
17. Kosar A, Sarica K, Kupeli B, Alcigir G, Kupeli S. Testicular torsion: evaluation of contralateral testicular histology. Int Urol Nephrol 1997; 29:351-356.
18. Andiran F, Okur DH, Kilink A, Gedikoglu G, Kilink K, Tanyel FC. Do experimentally induced ipsilateral testicular torsion, vas deferens obstruction, intra-abdominal testis or venous obstruction damage the contralateral testis through a common mechanism? BJU Intern 2000; 85:330-335.
19. Prillaman HM, Turner TT. Rescue of testicular function after acute experimental torsion. J Urol 1997; 157:340-345.
20. Kunduzova OR, Bianchi P, Pizzinat N, Escourrou G, Seguelas MH, Parini A, Cambon C. Regulation of JNK/ERK activation, cell apoptosis, and tissue regeneration by monoamine oxidase after renal ischemia reperfusion. FASEB J 2002; 16:1129-1131.
21. Bishopric NH, Andreka P, Slepak T, Webster KA. Molecular mechanisms of apoptosis in the cardiac myocyte. Curr Opin Pharmacol 2001; 1:141-150.
22. Seger R, Krebs EG. The MAPK signaling cascade. FASEB J 1995; 9:726-735.
23. Derijard B, Hibi M, Wu H, Barrett T, Su B, Deng T, Karin M, Davis RJ. JNK1: a protein kinase stimulated by UV light and Ha-ras that binds and phosphorylates the c-jun activation domain. Cell 1994; 76:1025-1037.
24. Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein and UV responsive protein kinase that binds and potentiates the c-jun activation domain. Genes Dev 1993; 7:2135-2148.
25. Kyriakis JM, Banerjee P, Nikolakaki E, Dai T, Rubie EA, Ahmad MF, Avruch J, Woodgett JR. The stress-activated protein kinase subfamily of c-jun kinases. Nature 1994; 369:156-160.
26. Squadrito F, Minutoli L, Esposito M, Bitto A, Marini H, Seminara P, Crisafulli A, Passaniti M, Adamo EB, Marini R, Guarini S, Altavilla D. Lipid peroxidation triggers both c-Jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK) activation and neointimal hyperplasia induced by cessation of blood in the mouse carotid artery. Atherosclerosis 2005; 178:295-302.
27. Romeo C, Antonuccio P, Esposito M, Marini H, Impellizzeri P, Turiaco N, Altavilla D, Bitto A, Zuccarello B, Squadrito F. Raxofelast, a hydrophilic vitamin E-like antioxidant, reduces testicular ischemia-reperfusion injury. Urol Res 2004; 32:367-371.
28. Bukare O, Ashendel CL, Peng H, Zalkow LH, Burgess EM. Synthesis and MEK1 inhibitory activities of imido-substituted 2-chloro-1,4-naphthoquinones. Bioorg Med Chem 2003; 11:3165-3170.
29. Reiners JJ, Lee J, Clift ER, Dudley DT, Myrand SP. PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase. Mol Pharmacol 1998; 53:438-445.
30. Maher P. How protein kinase C activation protects nerve cells from oxidative stress-induced cell death. J Neurosci 2001; 21:2929-2938.