The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias

Nucleic Acids Research

Volumn 40, Issue 20, 2012, Pages 10366-10374

  Fabbretti, Attilio ^a   Brandi, Letizia ^a   Petrelli, Dezemona ^a   Pon, Cynthia L ^a   Castañedo, Nilo R ^b   Medina, Ricardo ^b   Gualerzi, Claudio O ^c  

^a UNIVERSITY OF CAMERINO   (Italy)

^b CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 BROMO 5 (2 BROMO 2 NITROVINYL)FURAN; ANTIBIOTIC AGENT; FURVINA; MESSENGER RNA; PURINE; PYRIMIDINE; RNA 16S; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; DRUG STRUCTURE; DRUG TARGETING; ESCHERICHIA COLI; NONHUMAN; P SITE; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; RIBOSOME SUBUNIT; START CODON; TRANSLATION INITIATION;

ANTI-BACTERIAL AGENTS; BINDING SITES; CODON, INITIATOR; FURANS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; RIBOSOME SUBUNITS, SMALL, BACTERIAL; VINYL COMPOUNDS;

EID: 84869023625     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks822     Document Type: Article

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