β-TrCp-Mediated IRAK1 degradation releases TAK1-TRAF6 from the membrane to the cytosol for TAK1-dependent NF-κB activation

Molecular and Cellular Biology

Volumn 32, Issue 19, 2012, Pages 3990-4000

  Cui, Wei ^a,b   Xiao, Nengming ^b   Xiao, Hui ^b,c   Zhou, Hao ^b   Yu, Minjia ^b   Gu, Jun ^a   Li, Xiaoxia ^b  

^a PEKING UNIVERSITY   (China)

^b LERNER RESEARCH INSTITUTE   (United States)

^c INSTITUTE PASTEUR OF SHANGHAI   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; CULLIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; PROTEIN; PROTEIN DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CYTOSOL; EMBRYO; HUMAN; HUMAN CELL; MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; UBIQUITINATION;

BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CELL LINE; CYTOSOL; GENE KNOCKDOWN TECHNIQUES; HUMANS; I-KAPPA B KINASE; INTERLEUKIN-1; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MAP KINASE KINASE 4; MAP KINASE KINASE KINASES; NF-KAPPA B; PHOSPHORYLATION; PROTEIN TRANSPORT; TNF RECEPTOR-ASSOCIATED FACTOR 6; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84868702961     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00722-12     Document Type: Article

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