Metabolism and elimination of 14C-donepezil in healthy volunteers: A single-dose study

British Journal of Clinical Pharmacology, Supplement

Volumn 46, Issue 1, 1998, Pages 19-24

  Tiseo, P J ^a   Perdomo, C A ^a   Friedhoff, L T ^a  

^a EISAI INC   (United States)

Author keywords

Alzheimer's disease; Donepezil; Elimination; Metabolism

Indexed keywords

CARBON 14; CHOLINESTERASE INHIBITOR; DONEPEZIL; DRUG METABOLITE; CARBON; INDAN DERIVATIVE; PIPERIDINE DERIVATIVE;

ADULT; ARTICLE; CLINICAL TRIAL; DEALKYLATION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG FECES LEVEL; DRUG GLUCURONIDATION; DRUG HYDROLYSIS; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG OXIDATION; DRUG URINE LEVEL; HEADACHE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RADIOACTIVITY; THIN LAYER CHROMATOGRAPHY; BLOOD; CHEMISTRY; FECES; METABOLIC CLEARANCE RATE; MIDDLE AGED; URINE;

ADMINISTRATION, ORAL; ADULT; CARBON RADIOISOTOPES; CHOLINESTERASE INHIBITORS; FECES; HUMANS; INDANS; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; PIPERIDINES;

EID: 0032200806     PISSN: 02643774     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1998.0460s1019.x     Document Type: Article

References (3)

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