-
1
-
-
79959706804
-
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for contextdependent mitotic signaling
-
doi:10.1126/scisignal.2001796
-
Alexander J, et al. 2011. Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for contextdependent mitotic signaling. Sci. Signal. 4:ra42. doi:10.1126/ scisignal.2001796.
-
(2011)
Sci. Signal.
, vol.4
-
-
Alexander, J.1
-
2
-
-
4444291856
-
Sgt1 associates with Hsp90: an initial step of assembly of the core kinetochore complex
-
Bansal PK, Abdulle R, Kitagawa K. 2004. Sgt1 associates with Hsp90: an initial step of assembly of the core kinetochore complex. Mol. Cell. Biol. 24:8069-8079.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8069-8079
-
-
Bansal, P.K.1
Abdulle, R.2
Kitagawa, K.3
-
3
-
-
67650539066
-
Sgt1 dimerization is negatively regulated by protein kinase CK2-mediated phosphorylation at Ser361
-
Bansal PK, Mishra A, High AA, Abdulle R, Kitagawa K. 2009. Sgt1 dimerization is negatively regulated by protein kinase CK2-mediated phosphorylation at Ser361. J. Biol. Chem. 284:18692-18698.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 18692-18698
-
-
Bansal, P.K.1
Mishra, A.2
High, A.A.3
Abdulle, R.4
Kitagawa, K.5
-
6
-
-
33751232957
-
The conservedKMNnetwork constitutes the core microtubule-binding site of the kinetochore
-
Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A. 2006. The conservedKMNnetwork constitutes the core microtubule-binding site of the kinetochore. Cell 127:983-997.
-
(2006)
Cell
, vol.127
, pp. 983-997
-
-
Cheeseman, I.M.1
Chappie, J.S.2
Wilson-Kubalek, E.M.3
Desai, A.4
-
7
-
-
4444241998
-
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension
-
Cheeseman IM, et al. 2004. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 18:2255-2268.
-
(2004)
Genes Dev
, vol.18
, pp. 2255-2268
-
-
Cheeseman, I.M.1
-
8
-
-
77951198477
-
Hsp90- Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites
-
Davies AE, Kaplan KB. 2010. Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. J. Cell Biol. 189:261-274.
-
(2010)
J. Cell Biol.
, vol.189
, pp. 261-274
-
-
Davies, A.E.1
Kaplan, K.B.2
-
9
-
-
33751227843
-
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
-
DeLuca JG, et al. 2006. Kinetochore microtubule dynamics and attachment stability are regulated by Hec1. Cell 127:969 -982.
-
(2006)
Cell
, vol.127
, pp. 969-982
-
-
DeLuca, J.G.1
-
10
-
-
33745004786
-
The human CENP-A centromeric nucleosomeassociated complex
-
Foltz DR, et al. 2006. The human CENP-A centromeric nucleosomeassociated complex. Nat. Cell Biol. 8:458-469.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 458-469
-
-
Foltz, D.R.1
-
11
-
-
0029079267
-
Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function
-
Golsteyn RM, Mundt KE, Fry AM, Nigg EA. 1995. Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. J. Cell Biol. 129:1617-1628.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 1617-1628
-
-
Golsteyn, R.M.1
Mundt, K.E.2
Fry, A.M.3
Nigg, E.A.4
-
12
-
-
33244490241
-
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition
-
Goto H, et al. 2006. Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat. Cell Biol. 8:180 -187.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 180-187
-
-
Goto, H.1
-
13
-
-
41549127153
-
Dynamics of inner kinetochore assembly and maintenance in living cells
-
Hemmerich P, et al. 2008. Dynamics of inner kinetochore assembly and maintenance in living cells. J. Cell Biol. 180:1101-1114.
-
(2008)
J. Cell Biol
, vol.180
, pp. 1101-1114
-
-
Hemmerich, P.1
-
14
-
-
0030828073
-
2 and spreads in an ordered fashion coincident with mitotic chromosome condensation
-
2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 106:348 -360.
-
(1997)
Chromosoma
, vol.106
, pp. 348-360
-
-
Hendzel, M.J.1
-
15
-
-
70349546862
-
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution
-
Holt LJ, et al. 2009. Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science 325:1682-1686.
-
(2009)
Science
, vol.325
, pp. 1682-1686
-
-
Holt, L.J.1
-
16
-
-
57149129148
-
CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore
-
Hori T, et al. 2008. CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore. Cell 135: 1039-1052.
-
(2008)
Cell
, vol.135
, pp. 1039-1052
-
-
Hori, T.1
-
17
-
-
0034683744
-
Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells
-
Howell BJ, Hoffman DB, Fang G, Murray AW, Salmon ED. 2000. Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells. J. Cell Biol. 150:1233-1250.
-
(2000)
J. Cell Biol
, vol.150
, pp. 1233-1250
-
-
Howell, B.J.1
Hoffman, D.B.2
Fang, G.3
Murray, A.W.4
Salmon, E.D.5
-
18
-
-
75749117934
-
Mechanisms of force generation by end-on kinetochore-microtubule attachments
-
Joglekar AP, Bloom KS, Salmon ED. 2010. Mechanisms of force generation by end-on kinetochore-microtubule attachments. Curr. Opin. Cell Biol. 22:57- 67.
-
(2010)
Curr. Opin. Cell Biol
, vol.22
, pp. 57-67
-
-
Joglekar, A.P.1
Bloom, K.S.2
Salmon, E.D.3
-
19
-
-
33751070826
-
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation
-
Kang YH, et al. 2006. Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Mol. Cell 24:409-422.
-
(2006)
Mol. Cell
, vol.24
, pp. 409-422
-
-
Kang, Y.H.1
-
20
-
-
79959735228
-
Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells
-
doi:10.1126/scisignal.2001497
-
Kettenbach AN, et al. 2011. Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells. Sci. Signal. 4:rs5. doi:10.1126/scisignal.2001497.
-
(2011)
Sci. Signal.
, vol.4
-
-
Kettenbach, A.N.1
-
21
-
-
0033166694
-
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex
-
Kitagawa K, Skowyra D, Elledge SJ, Harper JW, Hieter P. 1999. SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol. Cell 4:21-33.
-
(1999)
Mol. Cell
, vol.4
, pp. 21-33
-
-
Kitagawa, K.1
Skowyra, D.2
Elledge, S.J.3
Harper, J.W.4
Hieter, P.5
-
22
-
-
12344266713
-
The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments
-
Lampson MA, Kapoor TM. 2005. The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nat. Cell Biol. 7:93-98.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 93-98
-
-
Lampson, M.A.1
Kapoor, T.M.2
-
23
-
-
33846931644
-
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1
-
Lenart P, et al. 2007. The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr. Biol. 17:304 -315.
-
(2007)
Curr. Biol.
, vol.17
, pp. 304-315
-
-
Lenart, P.1
-
24
-
-
4744356146
-
The interaction between Sgt1p and Skp1p is regulated by HSP90 chaperones and is required for proper CBF3 assembly
-
Lingelbach LB, Kaplan KB. 2004. The interaction between Sgt1p and Skp1p is regulated by HSP90 chaperones and is required for proper CBF3 assembly. Mol. Cell. Biol. 24:8938-8950.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8938-8950
-
-
Lingelbach, L.B.1
Kaplan, K.B.2
-
25
-
-
0037172998
-
Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA
-
Liu X, Erikson RL. 2002. Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA. Proc. Natl. Acad. Sci. U. S. A. 99:8672- 8676.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 8672-8676
-
-
Liu, X.1
Erikson, R.L.2
-
26
-
-
34247605084
-
Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate
-
Lowery DM, et al. 2007. Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate. EMBO J. 26:2262- 2273.
-
(2007)
EMBO J
, vol.26
, pp. 2262-2273
-
-
Lowery, D.M.1
-
27
-
-
59649124272
-
Sgt1, a co-chaperone of Hsp90 stabilizes Polo and is required for centrosome organization
-
Martins T, Maia AF, Steffensen S, Sunkel CE. 2009. Sgt1, a co-chaperone of Hsp90 stabilizes Polo and is required for centrosome organization. EMBO J. 28:234 -247.
-
(2009)
EMBO J
, vol.28
, pp. 234-247
-
-
Martins, T.1
Maia, A.F.2
Steffensen, S.3
Sunkel, C.E.4
-
28
-
-
0033615357
-
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen
-
Mayer TU, et al. 1999. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science 286:971-974.
-
(1999)
Science
, vol.286
, pp. 971-974
-
-
Mayer, T.U.1
-
29
-
-
0021686169
-
Dynamic instability of microtubule growth
-
Mitchison T, Kirschner M. 1984. Dynamic instability of microtubule growth. Nature 312:237-242.
-
(1984)
Nature
, vol.312
, pp. 237-242
-
-
Mitchison, T.1
Kirschner, M.2
-
30
-
-
0021711717
-
Microtubule assembly nucleated by isolated centrosomes
-
Mitchison T, Kirschner M. 1984. Microtubule assembly nucleated by isolated centrosomes. Nature 312:232-237.
-
(1984)
Nature
, vol.312
, pp. 232-237
-
-
Mitchison, T.1
Kirschner, M.2
-
31
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
Musacchio A, Salmon ED. 2007. The spindle-assembly checkpoint in space and time. Nat. Rev. Mol. Cell Biol. 8:379 -393.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
32
-
-
33745972064
-
NudC is required for Plk1 targeting to the kinetochore and chromosome congression
-
Nishino M, et al. 2006. NudC is required for Plk1 targeting to the kinetochore and chromosome congression. Curr. Biol. 16:1414 -1421.
-
(2006)
Curr. Biol.
, vol.16
, pp. 1414-1421
-
-
Nishino, M.1
-
33
-
-
43049151493
-
Polo on the rise: from mitotic entry to cytokinesis with Plk1
-
Petronczki M, Lenart P, Peters JM. 2008. Polo on the rise: from mitotic entry to cytokinesis with Plk1. Dev. Cell 14:646-659.
-
(2008)
Dev. Cell
, vol.14
, pp. 646-659
-
-
Petronczki, M.1
Lenart, P.2
Peters, J.M.3
-
34
-
-
33746654121
-
Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1
-
Qi W, Tang Z, Yu H. 2006. Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. Mol. Biol. Cell 17:3705-3716.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 3705-3716
-
-
Qi, W.1
Tang, Z.2
Yu, H.3
-
35
-
-
3042842156
-
Sgt1p and Skp1p modulate the assembly and turnover of CBF3 complexes required for proper kinetochore function
-
Rodrigo-Brenni MC, Thomas S, Bouck DC, Kaplan KB. 2004. Sgt1p and Skp1p modulate the assembly and turnover of CBF3 complexes required for proper kinetochore function. Mol. Biol. Cell 15:3366 -3378.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3366-3378
-
-
Rodrigo-Brenni, M.C.1
Thomas, S.2
Bouck, D.C.3
Kaplan, K.B.4
-
36
-
-
4344619975
-
Sgt1 is required for human kinetochore assembly
-
Steensgaard P, et al. 2004. Sgt1 is required for human kinetochore assembly. EMBO Rep. 5:626-631.
-
(2004)
EMBO Rep
, vol.5
, pp. 626-631
-
-
Steensgaard, P.1
-
37
-
-
77955167321
-
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy
-
Strebhardt K. 2010. Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy. Nat. Rev. Drug Disc. 9:643- 660.
-
(2010)
Nat. Rev. Drug Disc.
, vol.9
, pp. 643-660
-
-
Strebhardt, K.1
-
38
-
-
4644266184
-
Roles of polo-like kinase 1 in the assembly of functional mitotic spindles
-
Sumara I, et al. 2004. Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr. Biol. 14:1712-1722.
-
(2004)
Curr. Biol.
, vol.14
, pp. 1712-1722
-
-
Sumara, I.1
-
39
-
-
33746094659
-
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1
-
Vassilev LT, et al. 2006. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc. Natl. Acad. Sci. U. S. A. 103: 10660-10665.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 10660-10665
-
-
Vassilev, L.T.1
-
40
-
-
65549149069
-
Protein architecture of the human kinetochore microtubule attachment site
-
Wan X, et al. 2009. Protein architecture of the human kinetochore microtubule attachment site. Cell 137:672- 684.
-
(2009)
Cell
, vol.137
, pp. 672-684
-
-
Wan, X.1
-
41
-
-
0032101688
-
Localization of Mad2 to kinetochores depends on microtubule attachment, not tension
-
Waters JC, Chen RH, Murray AW, Salmon ED. 1998. Localization of Mad2 to kinetochores depends on microtubule attachment, not tension. J. Cell Biol. 141:1181-1191.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1181-1191
-
-
Waters, J.C.1
Chen, R.H.2
Murray, A.W.3
Salmon, E.D.4
-
42
-
-
55349099213
-
Toward a molecular structure of the eukaryotic kinetochore
-
Welburn JP, Cheeseman IM. 2008. Toward a molecular structure of the eukaryotic kinetochore. Dev. Cell 15:645- 655.
-
(2008)
Dev. Cell
, vol.15
, pp. 645-655
-
-
Welburn, J.P.1
Cheeseman, I.M.2
|