Enhanced expression of human β-defensin 2 in peripheral lungs of patients with chronic obstructive pulmonary disease

Peptides

Volumn 38, Issue 2, 2012, Pages 350-356

  Liao, Zenglin ^a   Dong, Jiajia ^a   Hu, Xiaorong ^a   Wang, Tao ^a   Wan, Chun ^a   Li, Xiao'Ou ^a   Li, Lin ^a   Guo, Lingli ^a   Xu, Dan ^a   Wen, Fuqiang ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Cigarette smoking; COPD; Human defensin 2; IL 8; Lung function

Indexed keywords

BETA DEFENSIN 2; INTERLEUKIN 1BETA; INTERLEUKIN 8; MESSENGER RNA;

ARTICLE; BRONCHIOLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG; LUNG CANCER; LUNG FUNCTION; LUNG PARENCHYMA; LUNG RESECTION; MAJOR CLINICAL STUDY; NEOPLASM; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOKING;

BETA-DEFENSINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1BETA; INTERLEUKIN-8; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84868684848     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.09.013     Document Type: Article

References (42)

1. J. Ashitani, N. Matsumoto, and M. Nakazato Elevated levels of antimicrobial peptides in bronchoalveolar lavage fluid in patients with chronic eosinophilic pneumonia Respiration 74 2007 69 75
2. J. Ashitani, H. Mukae, and M. Nakazato Elevated concentrations of defensins in bronchoalveolar lavage fluid in diffuse panbronchiolitis Eur Respir J 11 January 1998 104 111
3. S. Baconnais, R. Tirouvanziam, and J.M. Zahm Ion composition and rheology of airway liquid from cystic fibrosis fetal tracheal xeno-grafts Am J Respir Cell Mol Biol 20 1999 605 611
4. R. Bals, and P.S. Hiemstra Antimicrobial peptides in COPD - basic biology and therapeutic applications Current Drug Targets 7 2006 743 750
5. P.J. Barnes Mediators of chronic obstructive pulmonary disease Pharmacol Rev 56 2004 515 548
6. M.L. Bartoli, A. Di Franco, and B. Vagaggini Biological markers in induced sputum of patients with different phenotypes of chronic airway obstruction Respiration 77 2009 265 272
7. R. Bascom Differential susceptibility to tobacco smoke: possible mechanisms Pharmacogenetics 1 1991 102 106
8. G.G. Brusselle, G.F. Joos, and K.R. Bracke New insights into the immunology of chronic obstructive pulmonary disease Lancet 378 2011 1015 1026
9. J.L. Corhay, M. Henket, D. Nguyen, B. Duysinx, J. Sele, and R. Louis Leukotriene B4 contributes to exhaled breath condensate and sputum neutrophil chemotaxis in COPD Chest 136 2009 1047 1054
10. T. Ganz Defensins: antimicrobial peptides of innate immunity Nat Rev Immunol 3 2003 710 720
11. M.J. Goldman, G.M. Anderson, E.D. Stolzenberg, U.P. Kari, M. Zasloff, and J.M. Wilson Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis Cell 88 1997 553 560
12. K. Gorska, R. Krenke, and J. Domagala-Kulawik Comparison of cellular and biochemical markers of airway inflammation in patients with mild-to-moderate asthma and chronic obstructive pulmonary disease: an induced sputum and bronchoalveolar lavage fluid study J Physiol Pharmacol 59 2008 271 283
13. E. Guaní-Guerra, T. Santos-Mendoza, S.O. Lugo-Reyes, and L.M. Terán Antimicrobial peptides: general overview and clinical implications in human health and disease Clin Immunol 135 2010 1 11
14. S.S. Hacievliyagil, H. Gunen, L.C. Mutlu, A.B. Karabulut, and I. Temel Association between cytokines in induced sputum and severity of chronic obstructive pulmonary disease Respir Med 100 2006 846 854
15. J. Harder, J. Bartels, E. Christophers, and J.M. Schröder A peptide antibiotic from human skin Nature 387 1997 861
16. L. Hazlett, and M.H. Wu Defensins in innate immunity Cell Tissue Res 343 2011 175 188
17. C. Herr, C. Beisswenger, and C. Hess Suppression of pulmonary innate host defence in smokers Thorax 64 2009 144 149
18. P.S. Hiemstra The role of epithelial beta-defensins and cathelicidins in host defense of the lung Exp Lung Res 33 2007 537 542
19. T. Hiratsuka, H. Mukae, and H. Iiboshi Increased concentrations of human beta-defensins in plasma and bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis Thorax 58 2003 425 430
20. J.C. Hogg, and W. Timens The pathology of chronic obstructive pulmonary disease Annu Rev Pathol 4 2009 435 459
21. V.M. Keatings, P.D. Collins, D.M. Scott, and P.J. Barnes Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma Am J Respir Crit Care Med 153 1996 530 534
22. Y.P. Lai, and R.L. Gallo AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense Trends Immunol 30 2009 131 141
23. H. Mukae, H. Ishimoto, and S. Yanagi Elevated BALF concentrations of alpha- and beta-defensins in patients with pulmonary alveolar proteinosis Respir Med 101 2007 715 721
24. H.Y. Nam, E.K. Ahn, and H.J. Kim Diesel exhaust particles increase IL-1β-induced human β-defensin expression via NF-κB-mediated pathway in human lung epithelial cells Part Fibre Toxicol 25 2006 3 9
25. E. Pace, M. Ferraro, and M.I. Minervini Beta defensin-2 is reduced in central but not in distal airways of smoker COPD patients PLoS ONE 7 2012 e33601
26. K.F. Rabe, S. Hurd, and A. Anzueto Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary Am J Respir Crit Care Med 176 2007 532 555
27. K.F. Rabe, and J.A. Wedzicha Controversies in treatment of chronic obstructive pulmonary disease Lancet 378 2011 1038 1047
28. I. Rahman, and I.M. Adcock Oxidative stress and redox regulation of lung inflammation in COPD Eur Respir J 28 2006 219 242
29. S.S. Salvi, and P.J. Barnes Chronic obstructive pulmonary disease in non-smokers Lancet 374 2009 733 743
30. H. Sarir, E. Mortaz, and K. Karimi Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages J Inflamm 6 2009 12 19
31. J.M. Schröder, and J. Harder Human beta-defensin-2 Int J Biochem Cell Biol 31 1999 645 651
32. B.C. Schutte, J.P. Mitros, and J.A. Bartlett Discovery of five conserved beta-defensin gene clusters using a computational search strategy Proc Natl Acad Sci USA 99 2002 2129 2133
33. J.L. Simpson, S. Phipps, and P.G. Gibson Inflammatory mechanisms and treatment of obstructive airway diseases with neutrophilic bronchitis Pharmacol Ther 124 2009 86 95
34. P.K. Singh, H.P. Jia, and K. Wiles Production of beta-defensins by human airway epithelia Proc Natl Acad Sci USA 95 1998 14961 14966
35. J.J. Smith, S.M. Travis, E.P. Greenberg, and M.J. Welsh Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid Cell 85 1996 229 236
36. B.B. Sun, F.Q. Wen, and H.X. Wang Effects of astragaloside IV on beta-defensin 2 expression in rat airway induced by cigarette smoking Med J West China 20 2008 482 484
37. T. Tomita, and T. Nagase Defensins as a mechanism of host defense and innate immunity Nippon Ronen Igakkai Zasshi 38 2001 440 443
38. Y. Tsutsumi-Ishii, and I. Nagaoka NF-κB-mediated transcriptional regulation of human beta-defensin-2 gene following lipopolysaccharide stimulation J Leukoc Biol 71 2002 154 162
39. S. Vylkova, N. Nayyar, W. Li, and M. Edgerton Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption Antimicrob Agents Chemother 51 2007 154 161
40. X. Wang, Z. Zhang, J.P. Louboutin, C. Moser, D.J. Weiner, and J.M. Wilson Airway epithelia regulate expression of human beta-defensin 2 through Toll-like receptor 2 FASEB J 17 2003 1727 1729
41. J. Zabner, J.J. Smith, P.H. Karp, J.H. Widdicombe, and M.J. Welsh Loss of CFTR chloride channels alters salt absorption by cystic fibrosis airway epithelia in vitro Mol Cell 2 1998 397 403
42. Y. Zhang, and J.F. Engelhardt Airway surface fluid volume and Cl content in cystic fibrosis and normal bronchial xenografts Am J Physiol 276 1999 C469 C476