Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems

DMM Disease Models and Mechanisms

Volumn 5, Issue 6, 2012, Pages 940-947

  Nelson, Scott A ^a   Li, Zhouyu ^a,e   Newton, Ian P ^a   Fraser, David ^a   Milne, Rachel E ^a   Martin, David M A ^a   Schiffmann, David ^b   Yang, Xuesong ^c   Dormann, Dirk ^d   Weijer, Cornelis J ^a   Appleton, Paul L ^a   Näthke, Inke S ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b ETHOS Health Communications   (United States)

^c MEDICAL COLLEGE OF JINAN UNIVERSITY   (China)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e SHANXI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; BETA CATENIN; CYCLIC AMP; F ACTIN;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL MIGRATION; CELL MOTILITY; CHEMOTAXIS; CHICKEN; COLON POLYPOSIS; COLORECTAL CANCER; CONTROLLED STUDY; DICTYOSTELIUM DISCOIDEUM; EMBRYO; EMBRYO DEVELOPMENT; GAIN OF FUNCTION MUTATION; GENETIC SUSCEPTIBILITY; INTESTINE CELL; MIGRATION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIMITIVE STREAK; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CELL MOVEMENT; CELL TRANSFORMATION, NEOPLASTIC; CHICK EMBRYO; DICTYOSTELIUM; ENTEROCYTES; FEMALE; GENES, DOMINANT; INTESTINE, SMALL; MALE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; PEPTIDE FRAGMENTS; PRIMITIVE STREAK;

DICTYOSTELIUM; MUS;

EID: 84868679536     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.008607     Document Type: Article

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