-
1
-
-
82555205202
-
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma
-
Bertolotto C, et al. 2011. A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature 480: 94-98.
-
(2011)
Nature
, vol.480
, pp. 94-98
-
-
Bertolotto, C.1
-
2
-
-
0038475967
-
Nuclear matrix proteins changes in cancerous prostate tissues and their prognostic value in clinically localized prostate cancer
-
Boccardo F, et al. 2003. Nuclear matrix proteins changes in cancerous prostate tissues and their prognostic value in clinically localized prostate cancer. Prostate 55:259-264.
-
(2003)
Prostate
, vol.55
, pp. 259-264
-
-
Boccardo, F.1
-
3
-
-
57349116775
-
Decreased recognition of SUMO-sensitive target genes following modification of SF-1 (NR5A1)
-
Campbell LA, et al. 2008. Decreased recognition of SUMO-sensitive target genes following modification of SF-1 (NR5A1). Mol. Cell. Biol. 28:7476-7486.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 7476-7486
-
-
Campbell, L.A.1
-
4
-
-
20344384269
-
SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin
-
Chalkiadaki A, Talianidis I. 2005. SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin. Mol. Cell. Biol. 25:5095-5105.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5095-5105
-
-
Chalkiadaki, A.1
Talianidis, I.2
-
5
-
-
78649396592
-
The SUMO pathway, emerging mechanisms that shape specificity, conjugation and recognition
-
Gareau JR, Lima CD. 2010. The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition. Nat. Rev. Mol. Cell Biol. 11:861-871.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 861-871
-
-
Gareau, J.R.1
Lima, C.D.2
-
7
-
-
67649173012
-
System-wide changes to SUMO modifications in response to heat shock
-
doi10. 1126/ scisignal.2000282
-
Golebiowski F, et al. 2009. System-wide changes to SUMO modifications in response to heat shock. Sci. Signal. 2:ra24. doi:10.1126/ scisignal.2000282.
-
Sci. Signal.
, vol.2
-
-
Golebiowski, F.1
-
8
-
-
66349136233
-
Extracellular signal-regulated kinase mitogen-activated protein kinase signaling initiates a dynamic interplay between sumoylation and ubiquitination to regulate the activity of the transcriptional activator PEA3
-
Guo B, Sharrocks AD. 2009. Extracellular signal-regulated kinase mitogen-activated protein kinase signaling initiates a dynamic interplay between sumoylation and ubiquitination to regulate the activity of the transcriptional activator PEA3. Mol. Cell. Biol. 29:3204-3218.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3204-3218
-
-
Guo, B.1
Sharrocks, A.D.2
-
10
-
-
37349118115
-
Androgen receptor (AR) coregulators, a diversity of functions converging on and regulating the AR transcriptional complex
-
Heemers HV, Tindall DJ. 2007. Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr. Rev. 28:778-808.
-
(2007)
Endocr. Rev.
, vol.28
, pp. 778-808
-
-
Heemers, H.V.1
Tindall, D.J.2
-
11
-
-
34250214907
-
SUMOrganization of the nucleus
-
Heun P. 2007. SUMOrganization of the nucleus. Curr. Opin. Cell Biol. 19:350-355.
-
(2007)
Curr. Opin. Cell Biol.
, vol.19
, pp. 350-355
-
-
Heun, P.1
-
12
-
-
63849165373
-
Kinetic complexity of the global response to glucocorticoid receptor action
-
John S, et al. 2009. Kinetic complexity of the global response to glucocorticoid receptor action. Endocrinology 150:1766-1774.
-
(2009)
Endocrinology
, vol.150
, pp. 1766-1774
-
-
John, S.1
-
13
-
-
61449247171
-
SUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells
-
Kaikkonen S, et al. 2009. SUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells. Mol. Endocrinol. 23:292-307.
-
(2009)
Mol. Endocrinol.
, vol.23
, pp. 292-307
-
-
Kaikkonen, S.1
-
14
-
-
0030904753
-
Interaction of androgen receptors with androgen response element in intact cells Roles of amino- and carboxyl-terminal regions and the ligand
-
Karvonen U, Kallio PJ, Jänne OA, Palvimo JJ. 1997. Interaction of androgen receptors with androgen response element in intact cells. Roles of amino- and carboxyl-terminal regions and the ligand. J. Biol. Chem. 272:15973-15979.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15973-15979
-
-
Karvonen, U.1
Kallio, P.J.2
Jänne, O.A.3
Palvimo, J.J.4
-
15
-
-
61349180289
-
Emerging roles of desumoylating enzymes
-
Kim JH, Baek SH. 2009. Emerging roles of desumoylating enzymes. Biochim. Biophys. Acta 1792:155-162.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 155-162
-
-
Kim, J.H.1
Baek, S.H.2
-
16
-
-
33847224474
-
Ligand-specific dynamics of the androgen receptor at its response element in living cells
-
Klokk TI, et al. 2007. Ligand-specific dynamics of the androgen receptor at its response element in living cells. Mol. Cell. Biol. 27:1823-1843.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1823-1843
-
-
Klokk, T.I.1
-
17
-
-
77952554163
-
Partners in crime, deregulation of AR activity and androgen synthesis in prostate cancer
-
Knudsen KE, Penning TM. 2010. Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer. Trends Endocrinol. Metab. 21:315-324.
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, pp. 315-324
-
-
Knudsen, K.E.1
Penning, T.M.2
-
18
-
-
0036291475
-
PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases
-
Kotaja N, Karvonen U, Jänne OA, Palvimo JJ. 2002. PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol. Cell. Biol. 22:5222-5234.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5222-5234
-
-
Kotaja, N.1
Karvonen, U.2
Jänne, O.A.3
Palvimo, J.J.4
-
19
-
-
79960261026
-
Sumoylation inhibits alpha-synuclein aggregation and toxicity
-
Krumova P, et al. 2011. Sumoylation inhibits alpha-synuclein aggregation and toxicity. J. Cell Biol. 194:49-60.
-
(2011)
J. Cell Biol.
, vol.194
, pp. 49-60
-
-
Krumova, P.1
-
20
-
-
43049096803
-
Arsenic degrades PML or PMLRARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway
-
Lallemand-Breitenbach V, et al. 2008. Arsenic degrades PML or PMLRARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat. Cell Biol. 10:547-555.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 547-555
-
-
Lallemand-Breitenbach, V.1
-
21
-
-
79961242786
-
Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development
-
Lee FY, et al. 2011. Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev. Cell 21:315-327.
-
(2011)
Dev. Cell
, vol.21
, pp. 315-327
-
-
Lee, F.Y.1
-
22
-
-
72149086961
-
Controlling hematopoiesis through sumoylationdependent regulation of a GATA factor
-
Lee HY, et al. 2009. Controlling hematopoiesis through sumoylationdependent regulation of a GATA factor. Mol. Cell 36:984-995.
-
(2009)
Mol. Cell
, vol.36
, pp. 984-995
-
-
Lee, H.Y.1
-
23
-
-
33750491062
-
Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors
-
Lin DY, et al. 2006. Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors. Mol. Cell 24:341-354.
-
(2006)
Mol. Cell
, vol.24
, pp. 341-354
-
-
Lin, D.Y.1
-
24
-
-
78149411481
-
Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells
-
Makkonen H, Kauhanen M, Jaaskelainen T, Palvimo JJ. 2011. Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells. Mol. Cell Endocrinol. 331:57-65.
-
(2011)
Mol. Cell Endocrinol.
, vol.331
, pp. 57-65
-
-
Makkonen, H.1
Kauhanen, M.2
Jaaskelainen, T.3
Palvimo, J.J.4
-
25
-
-
67651180792
-
Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers
-
Makkonen H, Kauhanen M, Paakinaho V, Jaaskelainen T, Palvimo JJ. 2009. Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers. Nucleic Acids Res. 37:4135-4148.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4135-4148
-
-
Makkonen, H.1
Kauhanen, M.2
Paakinaho, V.3
Jaaskelainen, T.4
Palvimo, J.J.5
-
26
-
-
33745611145
-
Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility
-
Marcelli M, et al. 2006. Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility. J. Cell. Biochem. 98:770-788.
-
(2006)
J. Cell. Biochem.
, vol.98
, pp. 770-788
-
-
Marcelli, M.1
-
27
-
-
69249090927
-
Small ubiquitin-like modifier (SUMO) modification of the androgen receptor attenuates polyglutamine-mediated aggregation
-
Mukherjee S, Thomas M, Dadgar N, Lieberman AP, Iniguez-Lluhi JA. 2009. Small ubiquitin-like modifier (SUMO) modification of the androgen receptor attenuates polyglutamine-mediated aggregation. J. Biol. Chem. 284:21296-21306.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 21296-21306
-
-
Mukherjee, S.1
Thomas, M.2
Dadgar, N.3
Lieberman, A.P.4
Iniguez-Lluhi, J.A.5
-
28
-
-
0037498052
-
Conjugation with the ubiquitinrelated modifier SUMO-1 regulates the partitioning of PML within the nucleus
-
Müller S, Matunis MJ, Dejean A. 1998. Conjugation with the ubiquitinrelated modifier SUMO-1 regulates the partitioning of PML within the nucleus. EMBO J. 17:61-70.
-
(1998)
EMBO J
, vol.17
, pp. 61-70
-
-
Müller, S.1
Matunis, M.J.2
Dejean, A.3
-
29
-
-
70350223560
-
Transcriptional suppression by transient recruitment of ARIP4 to sumoylated nuclear receptor Ad4BP/SF-1
-
Ogawa H, Komatsu T, Hiraoka Y, Morohashi K. 2009. Transcriptional suppression by transient recruitment of ARIP4 to sumoylated nuclear receptor Ad4BP/SF-1. Mol. Biol. Cell 20:4235-4245.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 4235-4245
-
-
Ogawa, H.1
Komatsu, T.2
Hiraoka, Y.3
Morohashi, K.4
-
30
-
-
73449092854
-
SUMO engages multiple corepressors to regulate chromatin structure and transcription
-
Ouyang J, Gill G. 2009. SUMO engages multiple corepressors to regulate chromatin structure and transcription. Epigenetics 4:440-444.
-
(2009)
Epigenetics
, vol.4
, pp. 440-444
-
-
Ouyang, J.1
Gill, G.2
-
31
-
-
0027408317
-
Nuclear matrix protein patterns in human benign prostatic hyperplasia and prostate cancer
-
Partin AW, et al. 1993. Nuclear matrix protein patterns in human benign prostatic hyperplasia and prostate cancer. Cancer Res. 53:744-746.
-
(1993)
Cancer Res
, vol.53
, pp. 744-746
-
-
Partin, A.W.1
-
32
-
-
0034687807
-
Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1)
-
Poukka H, Karvonen U, Jänne OA, Palvimo JJ. 2000. Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). Proc. Natl. Acad. Sci. U. S. A. 97:14145-14150.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 14145-14150
-
-
Poukka, H.1
Karvonen, U.2
Jänne, O.A.3
Palvimo, J.J.4
-
33
-
-
33645790779
-
NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression
-
Rosendorff A, et al. 2006. NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression. Proc. Natl. Acad. Sci. U. S. A. 103:5308-5313.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 5308-5313
-
-
Rosendorff, A.1
-
34
-
-
77953929082
-
SUMO functions in constitutive transcription and during activation of inducible genes in yeast
-
Rosonina E, Duncan SM, Manley JL. 2010. SUMO functions in constitutive transcription and during activation of inducible genes in yeast. Genes Dev. 24:1242-1252.
-
(2010)
Genes Dev
, vol.24
, pp. 1242-1252
-
-
Rosonina, E.1
Duncan, S.M.2
Manley, J.L.3
-
35
-
-
73649111322
-
PIAS proteins, pleiotropic interactors associated with SUMO
-
Rytinki MM, Kaikkonen S, Pehkonen P, Jaaskelainen T, Palvimo JJ. 2009. PIAS proteins: pleiotropic interactors associated with SUMO. Cell. Mol. Life Sci. 66:3029-3041.
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 3029-3041
-
-
Rytinki, M.M.1
Kaikkonen, S.2
Pehkonen, P.3
Jaaskelainen, T.4
Palvimo, J.J.5
-
37
-
-
45549093122
-
SUMOylation modulates the transcription repressor function of RIP140
-
Rytinki MM, Palvimo JJ. 2008. SUMOylation modulates the transcription repressor function of RIP140. J. Biol. Chem. 283:11586-11595.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 11586-11595
-
-
Rytinki, M.M.1
Palvimo, J.J.2
-
38
-
-
70350031566
-
SUMOylation attenuates the function of PGC-1alpha
-
Rytinki MM, Palvimo JJ. 2009. SUMOylation attenuates the function of PGC-1alpha. J. Biol. Chem. 284:26184-26193.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26184-26193
-
-
Rytinki, M.M.1
Palvimo, J.J.2
-
39
-
-
0034054669
-
Functional heterogeneity of small ubiquitinrelated protein modifiers SUMO-1 versus SUMO-2/3
-
Saitoh H, Hinchey J. 2000. Functional heterogeneity of small ubiquitinrelated protein modifiers SUMO-1 versus SUMO-2/3. J. Biol. Chem. 275: 6252-6258.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6252-6258
-
-
Saitoh, H.1
Hinchey, J.2
-
41
-
-
57049091711
-
The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle
-
Schimmel J, et al. 2008. The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle. Mol. Cell. Proteomics 7:2107-2122.
-
(2008)
Mol. Cell. Proteomics
, vol.7
, pp. 2107-2122
-
-
Schimmel, J.1
-
42
-
-
77956793432
-
Molecular genetics of prostate cancer, new prospects for old challenges
-
Shen MM, Abate-Shen C. 2010. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev. 24:1967-2000.
-
(2010)
Genes Dev
, vol.24
, pp. 1967-2000
-
-
Shen, M.M.1
Abate-Shen, C.2
-
43
-
-
40849150778
-
Identification of SUMO-dependent chromatinassociated transcriptional repression components by a genome-wide RNAi screen
-
Stielow B, et al. 2008. Identification of SUMO-dependent chromatinassociated transcriptional repression components by a genome-wide RNAi screen. Mol. Cell 29:742-754.
-
(2008)
Mol. Cell
, vol.29
, pp. 742-754
-
-
Stielow, B.1
-
44
-
-
34648816891
-
Conserved function of RNF4 family proteins in eukaryotes, targeting a ubiquitin ligase to SUMOylated proteins
-
Sun H, Leverson JD, Hunter T. 2007. Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. EMBO J. 26:4102-4112.
-
(2007)
EMBO J
, vol.26
, pp. 4102-4112
-
-
Sun, H.1
Leverson, J.D.2
Hunter, T.3
-
45
-
-
0029863813
-
ATP-dependent release of glucocorticoid receptors from the nuclear matrix
-
Tang Y, DeFranco DB. 1996. ATP-dependent release of glucocorticoid receptors from the nuclear matrix. Mol. Cell. Biol. 16:1989-2001.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 1989-2001
-
-
Tang, Y.1
DeFranco, D.B.2
-
46
-
-
43049093756
-
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
-
Tatham MH, et al. 2008. RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Nat. Cell Biol. 10:538-546.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 538-546
-
-
Tatham, M.H.1
-
47
-
-
0035929557
-
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
-
Tatham MH, et al. 2001. Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. 276:35368-35374.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35368-35374
-
-
Tatham, M.H.1
-
48
-
-
79959381925
-
Comparative proteomic analysis identifies a role for SUMO in protein quality control
-
doi10. 1126/scisignal.2001484
-
Tatham MH, Matic I, Mann M, Hay RT. 2011. Comparative proteomic analysis identifies a role for SUMO in protein quality control. Sci. Signal. 4:rs4. doi:10.1126/scisignal.2001484.
-
(2011)
Sci. Signal.
, vol.4
-
-
Tatham, M.H.1
Matic, I.2
Mann, M.3
Hay, R.T.4
-
49
-
-
79958244237
-
Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation
-
Treuter E, Venteclef N. 2011. Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation. Biochim. Biophys. Acta 1812:909-918.
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 909-918
-
-
Treuter, E.1
Venteclef, N.2
-
50
-
-
77951211689
-
RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2alpha
-
van Hagen M, Overmeer RM, Abolvardi SS, Vertegaal AC. 2010. RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2alpha. Nucleic Acids Res. 38:1922-1931.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 1922-1931
-
-
van Hagen, M.1
Overmeer, R.M.2
Abolvardi, S.S.3
Vertegaal, A.C.4
-
51
-
-
76749125430
-
GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response
-
Venteclef N, et al. 2010. GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response. Genes Dev. 24:381-395.
-
(2010)
Genes Dev
, vol.24
, pp. 381-395
-
-
Venteclef, N.1
-
52
-
-
77952566949
-
Mechanisms, regulation and consequences of protein SUMOylation
-
Wilkinson KA, Henley JM. 2010. Mechanisms, regulation and consequences of protein SUMOylation. Biochem. J. 428:133-145.
-
(2010)
Biochem. J.
, vol.428
, pp. 133-145
-
-
Wilkinson, K.A.1
Henley, J.M.2
-
53
-
-
1542285164
-
SUMO promotes HDAC-mediated transcriptional repression
-
Yang SH, Sharrocks AD. 2004. SUMO promotes HDAC-mediated transcriptional repression. Mol. Cell 13:611-617.
-
(2004)
Mol. Cell
, vol.13
, pp. 611-617
-
-
Yang, S.H.1
Sharrocks, A.D.2
-
54
-
-
38549139741
-
Transient global cerebral ischemia induces a massive increase in protein sumoylation
-
Yang W, Sheng H, Warner DS, Paschen W. 2008. Transient global cerebral ischemia induces a massive increase in protein sumoylation. J. Cereb. Blood Flow Metab. 28:269-279.
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, pp. 269-279
-
-
Yang, W.1
Sheng, H.2
Warner, D.S.3
Paschen, W.4
-
55
-
-
82555187007
-
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
-
Yokoyama S, et al. 2011. A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature 480:99-103.
-
(2011)
Nature
, vol.480
, pp. 99-103
-
-
Yokoyama, S.1
|