메뉴 건너뛰기




Volumn 107, Issue 3, 2008, Pages 768-778

Expression and possible role of creatine transporter in the brain and at the blood-cerebrospinal fluid barrier as a transporting protein of guanidinoacetate, an endogenous convulsant

Author keywords

Blood cerebrospinal fluid barrier; Choroid plexus; Convulsion; Creatine transporter; Expression; Guanidinoacetate

Indexed keywords

CARRIER PROTEIN; CREATINE; CREATINE TRANSPORTER; GUANIDINE DERIVATIVE; GUANIDINOACETIC ACID; MANNITOL; UNCLASSIFIED DRUG;

EID: 53149101457     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05652.x     Document Type: Article
Times cited : (49)

References (39)
  • 3
    • 43149113670 scopus 로고    scopus 로고
    • AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: A review
    • Braissant O. Henry H. (2008) AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: a review. J. Inherit. Metab. Dis. 31, 230 234.
    • (2008) J. Inherit. Metab. Dis. , vol.31 , pp. 230-234
    • Braissant, O.1    Henry, H.2
  • 4
    • 0035977693 scopus 로고    scopus 로고
    • Endogenous synthesis and transport of creatine in the rat brain: An in situ hybridization study
    • Braissant O., Henry H., Loup M., Eilers B. Bachmann C. (2001) Endogenous synthesis and transport of creatine in the rat brain: an in situ hybridization study. Brain Res. Mol. Brain Res. 86, 193 201.
    • (2001) Brain Res. Mol. Brain Res. , vol.86 , pp. 193-201
    • Braissant, O.1    Henry, H.2    Loup, M.3    Eilers, B.4    Bachmann, C.5
  • 5
    • 23044475041 scopus 로고    scopus 로고
    • Creatine synthesis and transport during rat embryogenesis: Spatiotemporal expression of AGAT, GAMT and CT1
    • Braissant O., Henry H., Villard A. M., Speer O., Wallimann T. Bachmann C. (2005) Creatine synthesis and transport during rat embryogenesis: spatiotemporal expression of AGAT, GAMT and CT1. BMC Dev. Biol. 5, 9.
    • (2005) BMC Dev. Biol. , vol.5 , pp. 9
    • Braissant, O.1    Henry, H.2    Villard, A.M.3    Speer, O.4    Wallimann, T.5    Bachmann, C.6
  • 6
    • 0018025773 scopus 로고
    • Iodide and thiocyanate efflux from brain following injection into rat caudate nucleus
    • Cserr H. F. Berman B. J. (1978) Iodide and thiocyanate efflux from brain following injection into rat caudate nucleus. Am. J. Physiol. 235, F331 F337.
    • (1978) Am. J. Physiol. , vol.235
    • Cserr, H.F.1    Berman, B.J.2
  • 7
    • 0034025972 scopus 로고    scopus 로고
    • Developmental and adult expression of rat calcium-sensing receptor transcripts in neurons and oligodendrocytes
    • Ferry S., Traiffort E., Stinnakre J. Ruat M. (2000) Developmental and adult expression of rat calcium-sensing receptor transcripts in neurons and oligodendrocytes. Eur. J. Neurosci. 12, 872 884.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 872-884
    • Ferry, S.1    Traiffort, E.2    Stinnakre, J.3    Ruat, M.4
  • 8
    • 0027537622 scopus 로고
    • A Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidney. cDNA cloning and functional expression
    • Guimbal C. Kilimann M. W. (1993) A Na(+)-dependent creatine transporter in rabbit brain, muscle, heart, and kidney. cDNA cloning and functional expression. J. Biol. Chem. 268, 8418 8421.
    • (1993) J. Biol. Chem. , vol.268 , pp. 8418-8421
    • Guimbal, C.1    Kilimann, M.W.2
  • 9
    • 0028813282 scopus 로고
    • In situ hybridization analysis of CHOT1, a creatine transporter, in the rat central nervous system
    • Happe H. K. Murrin L. C. (1995) In situ hybridization analysis of CHOT1, a creatine transporter, in the rat central nervous system. J. Comp. Neurol. 351, 94 103.
    • (1995) J. Comp. Neurol. , vol.351 , pp. 94-103
    • Happe, H.K.1    Murrin, L.C.2
  • 10
    • 0037304972 scopus 로고    scopus 로고
    • A role for guanidino compounds in the brain
    • Hiramatsu M. (2003) A role for guanidino compounds in the brain. Mol. Cell. Biochem. 244, 57 62.
    • (2003) Mol. Cell. Biochem. , vol.244 , pp. 57-62
    • Hiramatsu, M.1
  • 11
    • 0023898536 scopus 로고
    • Measurement during convulsions of guanidino compound levels in cerebrospinal fluid collected with a catheter inserted into the cisterna magna of rabbits
    • Hiramatsu M., Edamatsu R., Fujikawa N., Shirasu A., Yamamoto M., Suzuki S. Mori A. (1988) Measurement during convulsions of guanidino compound levels in cerebrospinal fluid collected with a catheter inserted into the cisterna magna of rabbits. Brain Res. 455, 38 42.
    • (1988) Brain Res. , vol.455 , pp. 38-42
    • Hiramatsu, M.1    Edamatsu, R.2    Fujikawa, N.3    Shirasu, A.4    Yamamoto, M.5    Suzuki, S.6    Mori, A.7
  • 12
    • 4644290559 scopus 로고    scopus 로고
    • A new in vitro model for blood-cerebrospinal fluid barrier transport studies: An immortalized choroid plexus epithelial cell line derived from the tsA58 SV40 large T-antigen gene transgenic rat
    • Hosoya K., Hori S., Ohtsuki S. Terasaki T. (2004) A new in vitro model for blood-cerebrospinal fluid barrier transport studies: an immortalized choroid plexus epithelial cell line derived from the tsA58 SV40 large T-antigen gene transgenic rat. Adv. Drug Deliv. Rev. 56, 1875 1885.
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , pp. 1875-1885
    • Hosoya, K.1    Hori, S.2    Ohtsuki, S.3    Terasaki, T.4
  • 13
    • 0029972641 scopus 로고    scopus 로고
    • Choroid plexus taurine transport
    • Keep R. E. Xiang J. (1996) Choroid plexus taurine transport. Brain Res. 715, 17 24.
    • (1996) Brain Res. , vol.715 , pp. 17-24
    • Keep, R.E.1    Xiang, J.2
  • 14
    • 0034108608 scopus 로고    scopus 로고
    • In-vivo and in-vitro evidence of a carrier-mediated efflux transport system for oestrone-3-sulphate across the blood-cerebrospinal fluid barrier
    • Kitazawa T., Hosoya K., Takahashi T., Sugiyama Y. Terasaki T. (2000) In-vivo and in-vitro evidence of a carrier-mediated efflux transport system for oestrone-3-sulphate across the blood-cerebrospinal fluid barrier. J. Pharm. Pharmacol. 52, 281 288.
    • (2000) J. Pharm. Pharmacol. , vol.52 , pp. 281-288
    • Kitazawa, T.1    Hosoya, K.2    Takahashi, T.3    Sugiyama, Y.4    Terasaki, T.5
  • 15
    • 0035046185 scopus 로고    scopus 로고
    • Characterization of the amino acid transport of new immortalized choroid plexus epithelial cell lines: A novel in vitro system for investigating transport functions at the blood-cerebrospinal fluid barrier
    • Kitazawa T., Hosoya K., Watanabe M., Takashima T., Ohtsuki S., Takanaga H., Ueda M., Yanai N., Obinata M. Terasaki T. (2001) Characterization of the amino acid transport of new immortalized choroid plexus epithelial cell lines: a novel in vitro system for investigating transport functions at the blood-cerebrospinal fluid barrier. Pharm. Res. 18, 16 22.
    • (2001) Pharm. Res. , vol.18 , pp. 16-22
    • Kitazawa, T.1    Hosoya, K.2    Watanabe, M.3    Takashima, T.4    Ohtsuki, S.5    Takanaga, H.6    Ueda, M.7    Yanai, N.8    Obinata, M.9    Terasaki, T.10
  • 16
    • 0026078171 scopus 로고
    • Elevation of taurine in hippocampal extracellular fluid and cerebrospinal fluid of acutely hypoosmotic rats: Contribution by influx from blood?
    • Lehmann A., Carlstrom C., Nagelhus E. A. Ottersen O. P. (1991) Elevation of taurine in hippocampal extracellular fluid and cerebrospinal fluid of acutely hypoosmotic rats: contribution by influx from blood? J. Neurochem. 56, 690 697.
    • (1991) J. Neurochem. , vol.56 , pp. 690-697
    • Lehmann, A.1    Carlstrom, C.2    Nagelhus, E.A.3    Ottersen, O.P.4
  • 17
    • 34249783450 scopus 로고    scopus 로고
    • Severe epilepsy in X-linked creatine transporter defect (CRTR-D)
    • Mancardi M. M., Caruso U., Schiaffino M. C. et al. (2007) Severe epilepsy in X-linked creatine transporter defect (CRTR-D). Epilepsia 48, 1211 1213.
    • (2007) Epilepsia , vol.48 , pp. 1211-1213
    • Mancardi, M.M.1    Caruso, U.2    Schiaffino, M.C.3
  • 18
    • 0022636387 scopus 로고
    • Comparative study of guanidino compounds in serum and brain of mouse, rat, rabbit, and man
    • Marescau B., De Deyn P., Wiechert P., Van Gorp L. Lowenthal A. (1986) Comparative study of guanidino compounds in serum and brain of mouse, rat, rabbit, and man. J. Neurochem. 46, 717 720.
    • (1986) J. Neurochem. , vol.46 , pp. 717-720
    • Marescau, B.1    De Deyn, P.2    Wiechert, P.3    Van Gorp, L.4    Lowenthal, A.5
  • 20
    • 0037383621 scopus 로고    scopus 로고
    • Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells
    • Mori S., Takanaga H., Ohtsuki S., Deguchi T., Kang Y. S., Hosoya K. Terasaki T. (2003) Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. J. Cereb. Blood Flow Metab. 23, 432 440.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 432-440
    • Mori, S.1    Takanaga, H.2    Ohtsuki, S.3    Deguchi, T.4    Kang, Y.S.5    Hosoya, K.6    Terasaki, T.7
  • 21
    • 3042511855 scopus 로고    scopus 로고
    • Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-retinal barrier
    • Nakashima T., Tomi M., Katayama K., Tachikawa M., Watanabe M., Terasaki T. Hosoya K. (2004) Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-retinal barrier. J. Neurochem. 89, 1454 1461.
    • (2004) J. Neurochem. , vol.89 , pp. 1454-1461
    • Nakashima, T.1    Tomi, M.2    Katayama, K.3    Tachikawa, M.4    Watanabe, M.5    Terasaki, T.6    Hosoya, K.7
  • 22
    • 0036966277 scopus 로고    scopus 로고
    • Activation of GABA(A) receptors by guanidinoacetate: A novel pathophysiological mechanism
    • Neu A., Neuhoff H., Trube G., Fehr S., Ullrich K., Roeper J. Isbrandt D. (2002) Activation of GABA(A) receptors by guanidinoacetate: a novel pathophysiological mechanism. Neurobiol. Dis. 11, 298 307.
    • (2002) Neurobiol. Dis. , vol.11 , pp. 298-307
    • Neu, A.1    Neuhoff, H.2    Trube, G.3    Fehr, S.4    Ullrich, K.5    Roeper, J.6    Isbrandt, D.7
  • 23
    • 0028010511 scopus 로고
    • Kinetics of active efflux via choroid plexus of beta-lactam antibiotics from the CSF into the circulation
    • Ogawa M., Suzuki H., Sawada Y., Hanano M. Sugiyama Y. (1994) Kinetics of active efflux via choroid plexus of beta-lactam antibiotics from the CSF into the circulation. Am. J. Physiol. 266, R392 R399.
    • (1994) Am. J. Physiol. , vol.266
    • Ogawa, M.1    Suzuki, H.2    Sawada, Y.3    Hanano, M.4    Sugiyama, Y.5
  • 25
    • 0036568631 scopus 로고    scopus 로고
    • Origin and molecular specification of oligodendrocytes in the telencephalon
    • Qi Y., Stapp D. Qiu M. (2002) Origin and molecular specification of oligodendrocytes in the telencephalon. Trends Neurosci. 25, 223 225.
    • (2002) Trends Neurosci. , vol.25 , pp. 223-225
    • Qi, Y.1    Stapp, D.2    Qiu, M.3
  • 26
    • 3042544793 scopus 로고    scopus 로고
    • High prevalence of SLC6A8 deficiency in X-linked mental retardation
    • Rosenberg E. H., Almeida L. S., Kleefstra T. et al. (2004) High prevalence of SLC6A8 deficiency in X-linked mental retardation. Am. J. Hum. Genet. 75, 97 105.
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 97-105
    • Rosenberg, E.H.1    Almeida, L.S.2    Kleefstra, T.3
  • 28
    • 0029805748 scopus 로고    scopus 로고
    • Expression of the rat brain creatine transporter in situ and in transfected HeLa cells
    • Saltarelli M. D., Bauman A. L., Moore K. R., Bradley C. C. Blakely R. D. (1996) Expression of the rat brain creatine transporter in situ and in transfected HeLa cells. Dev. Neurosci. 18, 524 534.
    • (1996) Dev. Neurosci. , vol.18 , pp. 524-534
    • Saltarelli, M.D.1    Bauman, A.L.2    Moore, K.R.3    Bradley, C.C.4    Blakely, R.D.5
  • 29
    • 0028264171 scopus 로고
    • The putative rat choline transporter CHOT1 transports creatine and is highly expressed in neural and muscle-rich tissues
    • Schloss P., Mayser W. Betz H. (1994) The putative rat choline transporter CHOT1 transports creatine and is highly expressed in neural and muscle-rich tissues. Biochem. Biophys. Res. Commun. 198, 637 645.
    • (1994) Biochem. Biophys. Res. Commun. , vol.198 , pp. 637-645
    • Schloss, P.1    Mayser, W.2    Betz, H.3
  • 30
    • 22744453219 scopus 로고    scopus 로고
    • Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3
    • Shojaiefard M., Christie D. L. Lang F. (2005) Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3. Biochem. Biophys. Res. Commun. 334, 742 746.
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 742-746
    • Shojaiefard, M.1    Christie, D.L.2    Lang, F.3
  • 33
    • 0021918465 scopus 로고
    • Saturable transport of cimetidine from cerebrospinal fluid to blood in rats
    • Suzuki H., Sawada Y., Sugiyama Y., Iga T. Hanano M. (1985) Saturable transport of cimetidine from cerebrospinal fluid to blood in rats. J. Pharmacobiodyn. 8, 73 76.
    • (1985) J. Pharmacobiodyn. , vol.8 , pp. 73-76
    • Suzuki, H.1    Sawada, Y.2    Sugiyama, Y.3    Iga, T.4    Hanano, M.5
  • 35
    • 3142683647 scopus 로고    scopus 로고
    • Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-Mi and CK-B suggest a novel neuron-glial relationship for brain energy homeostasis
    • Tachikawa M., Fukaya M., Terasaki T., Ohtsuki S. Watanabe M. (2004) Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-Mi and CK-B suggest a novel neuron-glial relationship for brain energy homeostasis. Eur. J. Neurosci. 20, 144 160.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 144-160
    • Tachikawa, M.1    Fukaya, M.2    Terasaki, T.3    Ohtsuki, S.4    Watanabe, M.5
  • 36
    • 25644458407 scopus 로고    scopus 로고
    • Distinct spatio-temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain
    • Tachikawa M., Watanabe M., Hori S., Fukaya M., Ohtsuki S., Asashima T. Terasaki T. (2005) Distinct spatio-temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain. J. Neurochem. 95, 294 304.
    • (2005) J. Neurochem. , vol.95 , pp. 294-304
    • Tachikawa, M.1    Watanabe, M.2    Hori, S.3    Fukaya, M.4    Ohtsuki, S.5    Asashima, T.6    Terasaki, T.7
  • 37
    • 18144367335 scopus 로고    scopus 로고
    • Purification and characterization of the creatine transporter expressed at high levels in HEK293 cells
    • West M., Park D., Dodd J. R., Kistler J. Christie D. L. (2005) Purification and characterization of the creatine transporter expressed at high levels in HEK293 cells. Protein Expr. Purif. 41, 393 401.
    • (2005) Protein Expr. Purif. , vol.41 , pp. 393-401
    • West, M.1    Park, D.2    Dodd, J.R.3    Kistler, J.4    Christie, D.L.5
  • 38
    • 0033935979 scopus 로고    scopus 로고
    • Creatine and creatinine metabolism
    • Wyss M. Kaddurah-Daouk R. (2000) Creatine and creatinine metabolism. Physiol. Rev. 80, 1107 1213.
    • (2000) Physiol. Rev. , vol.80 , pp. 1107-1213
    • Wyss, M.1    Kaddurah-Daouk, R.2
  • 39
    • 0022615232 scopus 로고
    • An analysis program MULTI(ELS) based on extended nonlinear least squares method for microcomputers
    • Yamaoka K., Tanaka H., Okumura K., Yasuhara M. Hori R. (1986) An analysis program MULTI(ELS) based on extended nonlinear least squares method for microcomputers. J. Pharmacobiodyn. 9, 161 173.
    • (1986) J. Pharmacobiodyn. , vol.9 , pp. 161-173
    • Yamaoka, K.1    Tanaka, H.2    Okumura, K.3    Yasuhara, M.4    Hori, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.