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Volumn 13, Issue , 2012, Pages

Polymorphisms in the genes coding for iron binding and transporting proteins are associated with disability, severity, and early progression in multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

FERROPORTIN; HEPCIDIN; HFE PROTEIN; TRANSFERRIN;

EID: 84868621323     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-13-70     Document Type: Article
Times cited : (43)

References (59)
  • 1
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis - the plaque and its pathogenesis
    • 10.1056/NEJMra052130, 16510748
    • Frohman EM, Racke MK, Raine CS. Multiple sclerosis - the plaque and its pathogenesis. N Engl J Med 2006, 354:942-955. 10.1056/NEJMra052130, 16510748.
    • (2006) N Engl J Med , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 2
    • 0030788672 scopus 로고    scopus 로고
    • Iron deposits in multiple sclerosis and Alzheimer's disease brains
    • 10.1016/S0006-8993(97)00470-8, 9237552
    • LeVine SM. Iron deposits in multiple sclerosis and Alzheimer's disease brains. Brain Res 1997, 760:298-303. 10.1016/S0006-8993(97)00470-8, 9237552.
    • (1997) Brain Res , vol.760 , pp. 298-303
    • LeVine, S.M.1
  • 3
    • 0023869865 scopus 로고
    • Perivascular iron deposition and other vascular damage in multiple sclerosis
    • 10.1136/jnnp.51.2.260, 1031540, 3346691
    • Adams CW. Perivascular iron deposition and other vascular damage in multiple sclerosis. J Neurol Neurosurg Psychiatry 1988, 51:260-265. 10.1136/jnnp.51.2.260, 1031540, 3346691.
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 260-265
    • Adams, C.W.1
  • 4
    • 0024444624 scopus 로고
    • Pathology, histochemistry and immunocytochemistry of lesions in acute multiple sclerosis
    • 10.1016/0022-510X(89)90144-5, 2809622
    • Adams CW, Poston RN, Buk SJ. Pathology, histochemistry and immunocytochemistry of lesions in acute multiple sclerosis. J Neurol Sci 1989, 92:291-306. 10.1016/0022-510X(89)90144-5, 2809622.
    • (1989) J Neurol Sci , vol.92 , pp. 291-306
    • Adams, C.W.1    Poston, R.N.2    Buk, S.J.3
  • 5
    • 34250783638 scopus 로고    scopus 로고
    • Iron in chronic brain disorders: imaging and neurotherapeutic implications
    • 10.1016/j.nurt.2007.05.006, 1963417, 17599703
    • Stankiewicz J, Panter SS, Neema M, Arora A, Batt CE, Bakshi R. Iron in chronic brain disorders: imaging and neurotherapeutic implications. Neurotherapeutics 2007, 4:371-386. 10.1016/j.nurt.2007.05.006, 1963417, 17599703.
    • (2007) Neurotherapeutics , vol.4 , pp. 371-386
    • Stankiewicz, J.1    Panter, S.S.2    Neema, M.3    Arora, A.4    Batt, C.E.5    Bakshi, R.6
  • 6
    • 10944231116 scopus 로고    scopus 로고
    • Is stored iron safe?
    • 10.1016/j.lab.2004.10.006, 15614249
    • Sullivan JL. Is stored iron safe?. J Lab Clin Med 2004, 144:280-284. 10.1016/j.lab.2004.10.006, 15614249.
    • (2004) J Lab Clin Med , vol.144 , pp. 280-284
    • Sullivan, J.L.1
  • 7
    • 0034949363 scopus 로고    scopus 로고
    • Iron metabolism, free radicals, and oxidative injury
    • 10.1016/S0753-3322(01)00068-3, 11478586
    • Emerit J, Beaumont C, Trivi F. Iron metabolism, free radicals, and oxidative injury. Biomed Pharmacother 2001, 55:333-339. 10.1016/S0753-3322(01)00068-3, 11478586.
    • (2001) Biomed Pharmacother , vol.55 , pp. 333-339
    • Emerit, J.1    Beaumont, C.2    Trivi, F.3
  • 8
    • 33750709690 scopus 로고    scopus 로고
    • Brain iron metabolism
    • 10.1016/j.spen.2006.08.002, 17101452
    • Rouault TA, Cooperman S. Brain iron metabolism. Semin Pediatr Neurol 2006, 13:142-148. 10.1016/j.spen.2006.08.002, 17101452.
    • (2006) Semin Pediatr Neurol , vol.13 , pp. 142-148
    • Rouault, T.A.1    Cooperman, S.2
  • 9
    • 58149123408 scopus 로고    scopus 로고
    • Role of iron in neurotoxicity: a cause for concern in the elderly?
    • 10.1097/MCO.0b013e32831ba07c, 19057183
    • Stankiewicz JM, Brass SD. Role of iron in neurotoxicity: a cause for concern in the elderly?. Curr Opin Clin Nutr Metab Care 2009, 12:22-29. 10.1097/MCO.0b013e32831ba07c, 19057183.
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , pp. 22-29
    • Stankiewicz, J.M.1    Brass, S.D.2
  • 10
    • 80051660738 scopus 로고    scopus 로고
    • Iron chelation and neuroprotection in neurodegenerative diseases
    • 10.1007/s00702-010-0518-0, 21161300
    • Li X, Jankovic J, Le W. Iron chelation and neuroprotection in neurodegenerative diseases. J Neural Transm 2011, 118:473-477. 10.1007/s00702-010-0518-0, 21161300.
    • (2011) J Neural Transm , vol.118 , pp. 473-477
    • Li, X.1    Jankovic, J.2    Le, W.3
  • 11
    • 1842556542 scopus 로고    scopus 로고
    • The role of iron in the pathogenesis of experimental allergic encephalomyelitis and multiple sclerosis
    • 10.1196/annals.1306.021, 15105271
    • LeVine SM, Chakrabarty A. The role of iron in the pathogenesis of experimental allergic encephalomyelitis and multiple sclerosis. Ann N Y Acad Sci 2004, 1012:252-266. 10.1196/annals.1306.021, 15105271.
    • (2004) Ann N Y Acad Sci , vol.1012 , pp. 252-266
    • LeVine, S.M.1    Chakrabarty, A.2
  • 12
    • 33845317597 scopus 로고    scopus 로고
    • The big idea: iron-dependent inflammation in venous disease and proposed parallels in multiple sclerosis
    • 10.1258/jrsm.99.11.589, 1633548, 17082306
    • Zamboni P. The big idea: iron-dependent inflammation in venous disease and proposed parallels in multiple sclerosis. J R Soc Med 2006, 99:589-593. 10.1258/jrsm.99.11.589, 1633548, 17082306.
    • (2006) J R Soc Med , vol.99 , pp. 589-593
    • Zamboni, P.1
  • 13
    • 45649085636 scopus 로고    scopus 로고
    • Hypothetical molecular mechanisms by which local iron overload facilitates the development of venous leg ulcers and multiple sclerosis lesions
    • 10.1016/j.mehy.2008.02.009, 18400414
    • Simka M, Rybak Z. Hypothetical molecular mechanisms by which local iron overload facilitates the development of venous leg ulcers and multiple sclerosis lesions. Med Hypotheses 2008, 71:293-297. 10.1016/j.mehy.2008.02.009, 18400414.
    • (2008) Med Hypotheses , vol.71 , pp. 293-297
    • Simka, M.1    Rybak, Z.2
  • 15
    • 9344224529 scopus 로고    scopus 로고
    • A novel MHC class I like gene is mutated in patients with hereditary haemochromatosis
    • 10.1038/ng0896-399, 8696333
    • Feder JN, Gnirke A, Thomas W, Tsuchihashi Z, Ruddy DA, Basava A. A novel MHC class I like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996, 13:399-408. 10.1038/ng0896-399, 8696333.
    • (1996) Nat Genet , vol.13 , pp. 399-408
    • Feder, J.N.1    Gnirke, A.2    Thomas, W.3    Tsuchihashi, Z.4    Ruddy, D.A.5    Basava, A.6
  • 16
    • 70549104772 scopus 로고    scopus 로고
    • DNA-array of gene variants in venous leg ulcers: detection of prognostic indicators
    • 10.1016/j.jvs.2009.07.103, 19958990
    • Gemmati D, Federici F, Catozzi L, Gianesini S, Tacconi G, Scapoli GL, Zamboni P. DNA-array of gene variants in venous leg ulcers: detection of prognostic indicators. J Vasc Surg 2009, 50:1444-1451. 10.1016/j.jvs.2009.07.103, 19958990.
    • (2009) J Vasc Surg , vol.50 , pp. 1444-1451
    • Gemmati, D.1    Federici, F.2    Catozzi, L.3    Gianesini, S.4    Tacconi, G.5    Scapoli, G.L.6    Zamboni, P.7
  • 17
    • 2942703861 scopus 로고    scopus 로고
    • Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis
    • 10.1007/s00439-004-1095-9, 15014978
    • Rubio JP, Bahlo M, Tubridy N, Stankovich J, Burfoot R, Butzkueven H. Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis. Hum Genet 2004, 114:573-580. 10.1007/s00439-004-1095-9, 15014978.
    • (2004) Hum Genet , vol.114 , pp. 573-580
    • Rubio, J.P.1    Bahlo, M.2    Tubridy, N.3    Stankovich, J.4    Burfoot, R.5    Butzkueven, H.6
  • 19
    • 52949104025 scopus 로고    scopus 로고
    • Mutations in the hemochromatosis gene and the clinical outcome of multiple sclerosis
    • 10.1016/j.jneuroim.2008.06.036, 18675463
    • Ramagopalan SV, Cukjati M, Cernilec M, DeLuca GC, Dyment DA, Degenhardt A. Mutations in the hemochromatosis gene and the clinical outcome of multiple sclerosis. J Neuroimmunol 2008, 203:104-107. 10.1016/j.jneuroim.2008.06.036, 18675463.
    • (2008) J Neuroimmunol , vol.203 , pp. 104-107
    • Ramagopalan, S.V.1    Cukjati, M.2    Cernilec, M.3    DeLuca, G.C.4    Dyment, D.A.5    Degenhardt, A.6
  • 20
    • 79952725496 scopus 로고    scopus 로고
    • HFE gene polymorphisms and severity in Portuguese patients with multiple sclerosis
    • 10.1111/j.1468-1331.2010.03109.x, 20586792
    • Bettencourt A, Silva AM, Santos E, Gomes S, Mendonça D, Costa PP. HFE gene polymorphisms and severity in Portuguese patients with multiple sclerosis. Eur J Neurol 2011, 18:663-666. 10.1111/j.1468-1331.2010.03109.x, 20586792.
    • (2011) Eur J Neurol , vol.18 , pp. 663-666
    • Bettencourt, A.1    Silva, A.M.2    Santos, E.3    Gomes, S.4    Mendonça, D.5    Costa, P.P.6
  • 21
    • 0034733635 scopus 로고    scopus 로고
    • A novel mammalian iron-regulated protein involved in intracellular iron metabolism
    • 10.1074/jbc.M000713200, 10747949
    • Abboud S, Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 2000, 275:19906-19912. 10.1074/jbc.M000713200, 10747949.
    • (2000) J Biol Chem , vol.275 , pp. 19906-19912
    • Abboud, S.1    Haile, D.J.2
  • 22
    • 60749097763 scopus 로고    scopus 로고
    • Does the SLC40A1 gene modify HFE-related haemochromatosis phenotypes?
    • 10.1007/s00277-008-0590-9, 18820912
    • Altès A, Bach V, Ruiz A, Esteve A, Remacha AF, Sardà MP. Does the SLC40A1 gene modify HFE-related haemochromatosis phenotypes?. Ann Hematol 2009, 88:341-345. 10.1007/s00277-008-0590-9, 18820912.
    • (2009) Ann Hematol , vol.88 , pp. 341-345
    • Altès, A.1    Bach, V.2    Ruiz, A.3    Esteve, A.4    Remacha, A.F.5    Sardà, M.P.6
  • 23
    • 0347356639 scopus 로고    scopus 로고
    • Hepcidin, the recently identified peptide that appears to regulate iron absorption
    • Leong WI, Lönnerdal B. Hepcidin, the recently identified peptide that appears to regulate iron absorption. J Nutr 2004, 134:1-4.
    • (2004) J Nutr , vol.134 , pp. 1-4
    • Leong, W.I.1    Lönnerdal, B.2
  • 24
    • 70349104225 scopus 로고    scopus 로고
    • Association of hepcidin promoter c.-582 A>G variant and iron overload in thalassemia major
    • 10.3324/haematol.2009.006270, 2738723, 19734422
    • Andreani M, Radio FC, Testi M, De Bernardo C, Troiano M, Majore S. Association of hepcidin promoter c.-582 A>G variant and iron overload in thalassemia major. Haematologica 2009, 94:1293-1296. 10.3324/haematol.2009.006270, 2738723, 19734422.
    • (2009) Haematologica , vol.94 , pp. 1293-1296
    • Andreani, M.1    Radio, F.C.2    Testi, M.3    De Bernardo, C.4    Troiano, M.5    Majore, S.6
  • 25
    • 77952304008 scopus 로고    scopus 로고
    • The -582A>G variant of the HAMP promoter is not associated with high serum ferritin levels in normal subjects
    • 10.3324/haematol.2009.018986, 2864396, 20007145
    • Bruno F, Bonalumi S, Camaschella C, Ferrari M, Cremonesi L. The -582A>G variant of the HAMP promoter is not associated with high serum ferritin levels in normal subjects. Haematologica 2010, 95:849-850. 10.3324/haematol.2009.018986, 2864396, 20007145.
    • (2010) Haematologica , vol.95 , pp. 849-850
    • Bruno, F.1    Bonalumi, S.2    Camaschella, C.3    Ferrari, M.4    Cremonesi, L.5
  • 26
    • 78650956115 scopus 로고    scopus 로고
    • Genetic study of the hepcidin gene (HAMP) promoter and functional analysis of the c.-582A > G variant
    • 3004809, 21143959
    • Parajes S, González-Quintela A, Campos J, Quinteiro C, Domínguez F, Loidi L. Genetic study of the hepcidin gene (HAMP) promoter and functional analysis of the c.-582A > G variant. BMC Genet 2010, 11:110. 3004809, 21143959.
    • (2010) BMC Genet , vol.11 , pp. 110
    • Parajes, S.1    González-Quintela, A.2    Campos, J.3    Quinteiro, C.4    Domínguez, F.5    Loidi, L.6
  • 27
    • 0031605219 scopus 로고    scopus 로고
    • Transferrin, the transferrin receptor, and the uptake of iron by cells
    • Aisen P. Transferrin, the transferrin receptor, and the uptake of iron by cells. Met Ions Biol Syst 1998, 35:585-631.
    • (1998) Met Ions Biol Syst , vol.35 , pp. 585-631
    • Aisen, P.1
  • 28
    • 0033391822 scopus 로고    scopus 로고
    • The effect of transferrin polymorphisms on iron metabolism
    • 10.1006/bcmd.1999.0267, 10660486
    • Lee PL, Ho NJ, O, Beutler E. The effect of transferrin polymorphisms on iron metabolism. Blood Cells Mol Dis 1999, 25:374-379. 10.1006/bcmd.1999.0267, 10660486.
    • (1999) Blood Cells Mol Dis , vol.25 , pp. 374-379
    • Lee, P.L.1    Ho N.J.O2    Beutler, E.3
  • 29
    • 0022970119 scopus 로고
    • Effects of transferrin genetic phenotypes on total iron-binding capacity
    • 10.1159/000206128, 3096053
    • Wong CT, Saha N. Effects of transferrin genetic phenotypes on total iron-binding capacity. Acta Haematol 1986, 75:215-218. 10.1159/000206128, 3096053.
    • (1986) Acta Haematol , vol.75 , pp. 215-218
    • Wong, C.T.1    Saha, N.2
  • 30
  • 31
    • 0142091430 scopus 로고    scopus 로고
    • Association study between late-onset Alzheimer's disease and the transferrin gene polymorphisms in Chinese
    • 10.1016/S0304-3940(03)00837-1, 12951205
    • Zhang P, Yang Z, Zhang C, Lu Z, Shi X, Zheng W. Association study between late-onset Alzheimer's disease and the transferrin gene polymorphisms in Chinese. Neurosci Lett 2003, 349:209-211. 10.1016/S0304-3940(03)00837-1, 12951205.
    • (2003) Neurosci Lett , vol.349 , pp. 209-211
    • Zhang, P.1    Yang, Z.2    Zhang, C.3    Lu, Z.4    Shi, X.5    Zheng, W.6
  • 32
    • 77952685777 scopus 로고    scopus 로고
    • Alzheimer's Disease Neuroimaging Initiative: Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease
    • 2877151, 20029940
    • Kauwe JS. Alzheimer's Disease Neuroimaging Initiative: Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 2010, 153B:955-959. 2877151, 20029940.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 B , pp. 955-959
    • Kauwe, J.S.1
  • 33
    • 28544436950 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria"
    • 10.1002/ana.20703, 16283615
    • Polman CH, Reingold SC, Edan G, Filippi M, Hartung HP, Kappos L. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria". Ann Neurol 2005, 58:840-846. 10.1002/ana.20703, 16283615.
    • (2005) Ann Neurol , vol.58 , pp. 840-846
    • Polman, C.H.1    Reingold, S.C.2    Edan, G.3    Filippi, M.4    Hartung, H.P.5    Kappos, L.6
  • 34
    • 12344283809 scopus 로고    scopus 로고
    • Clinical features and diagnosis of multiple sclerosis
    • 10.1016/j.ncl.2004.09.003, 15661085
    • Lublin FD. Clinical features and diagnosis of multiple sclerosis. Neurol Clin 2005, 23:1-15. 10.1016/j.ncl.2004.09.003, 15661085.
    • (2005) Neurol Clin , vol.23 , pp. 1-15
    • Lublin, F.D.1
  • 36
    • 39049176585 scopus 로고    scopus 로고
    • Lack of clinical manifestation of hereditary haemochromatosis in South African patients with multiple sclerosis
    • Kotze MJ, de Villiers JN, Warnich L, Schmidt S, Carr J, Mansvelt E. Lack of clinical manifestation of hereditary haemochromatosis in South African patients with multiple sclerosis. Metab Brain Dis 2006, 21:109-120.
    • (2006) Metab Brain Dis , vol.21 , pp. 109-120
    • Kotze, M.J.1    de Villiers, J.N.2    Warnich, L.3    Schmidt, S.4    Carr, J.5    Mansvelt, E.6
  • 37
    • 79951652370 scopus 로고    scopus 로고
    • Serum elements and oxidative status in clinically isolated syndromes: imbalance and predictivity
    • 10.1212/WNL.0b013e31820af7de, 21300970
    • Ristori G, Brescianini S, Pino A, Visconti A, Vittori D, Coarelli G. Serum elements and oxidative status in clinically isolated syndromes: imbalance and predictivity. Neurology 2011, 76:549-555. 10.1212/WNL.0b013e31820af7de, 21300970.
    • (2011) Neurology , vol.76 , pp. 549-555
    • Ristori, G.1    Brescianini, S.2    Pino, A.3    Visconti, A.4    Vittori, D.5    Coarelli, G.6
  • 39
    • 58149347604 scopus 로고    scopus 로고
    • Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis
    • 10.1111/j.1552-6569.2008.00296.x, 2762230, 19192042
    • Neema M, Arora A, Healy BC, Guss ZD, Brass SD, Duan Y. Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis. J Neuroimaging 2009, 19:3-8. 10.1111/j.1552-6569.2008.00296.x, 2762230, 19192042.
    • (2009) J Neuroimaging , vol.19 , pp. 3-8
    • Neema, M.1    Arora, A.2    Healy, B.C.3    Guss, Z.D.4    Brass, S.D.5    Duan, Y.6
  • 40
    • 33746547762 scopus 로고    scopus 로고
    • Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosis
    • 10.1191/135248506ms1301oa, 16900757
    • Brass SD, Benedict RH, Weinstock-Guttman B, Munschauer F, Bakshi R. Cognitive impairment is associated with subcortical magnetic resonance imaging grey matter T2 hypointensity in multiple sclerosis. Mult Scler 2006, 12:437-444. 10.1191/135248506ms1301oa, 16900757.
    • (2006) Mult Scler , vol.12 , pp. 437-444
    • Brass, S.D.1    Benedict, R.H.2    Weinstock-Guttman, B.3    Munschauer, F.4    Bakshi, R.5
  • 41
    • 21344460544 scopus 로고    scopus 로고
    • MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis
    • 10.1016/j.jns.2005.02.009, 15993137
    • Tjoa CW, Benedict RH, Weinstock-Guttman B, Fabiano AJ, Bakshi R. MRI T2 hypointensity of the dentate nucleus is related to ambulatory impairment in multiple sclerosis. J Neurol Sci 2005, 234:17-24. 10.1016/j.jns.2005.02.009, 15993137.
    • (2005) J Neurol Sci , vol.234 , pp. 17-24
    • Tjoa, C.W.1    Benedict, R.H.2    Weinstock-Guttman, B.3    Fabiano, A.J.4    Bakshi, R.5
  • 42
    • 74449085808 scopus 로고    scopus 로고
    • Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins
    • 10.1007/s11011-009-9169-y, 2788140, 19851851
    • Rouault TA, Zhang DL, Jeong SY. Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins. Metab Brain Dis 2009, 24:673-684. 10.1007/s11011-009-9169-y, 2788140, 19851851.
    • (2009) Metab Brain Dis , vol.24 , pp. 673-684
    • Rouault, T.A.1    Zhang, D.L.2    Jeong, S.Y.3
  • 43
    • 1842608845 scopus 로고    scopus 로고
    • Iron metabolism and the IRE/IRP regulator system: an update
    • 10.1196/annals.1306.001, 15105251
    • Pantopoulos K. Iron metabolism and the IRE/IRP regulator system: an update. Ann NY Acad Sci 2004, 1012:1-13. 10.1196/annals.1306.001, 15105251.
    • (2004) Ann NY Acad Sci , vol.1012 , pp. 1-13
    • Pantopoulos, K.1
  • 44
    • 0345714885 scopus 로고    scopus 로고
    • Iron misregulation in the brain: a primary cause of neurodegenerative disorders
    • 10.1016/S1474-4422(03)00353-3, 12849213
    • Ke Y, Qian ZM. Iron misregulation in the brain: a primary cause of neurodegenerative disorders. Lancet Neurol 2003, 2:246-253. 10.1016/S1474-4422(03)00353-3, 12849213.
    • (2003) Lancet Neurol , vol.2 , pp. 246-253
    • Ke, Y.1    Qian, Z.M.2
  • 46
    • 64749109556 scopus 로고    scopus 로고
    • Dall'Ara S, Bartolomei I, Salvi F: Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis
    • 2647682, 19060024
    • Zamboni P, Galeotti R, Menegatti E, Malagoni AM, Tacconi G. Dall'Ara S, Bartolomei I, Salvi F: Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry 2009, 80:392-399. 2647682, 19060024.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 392-399
    • Zamboni, P.1    Galeotti, R.2    Menegatti, E.3    Malagoni, A.M.4    Tacconi, G.5
  • 47
    • 77951586507 scopus 로고    scopus 로고
    • Custom CGH array profiling of copy number variations (CNVs) on chromosome 6p21.32 (HLA locus) in patients with venous malformations associated with multiple sclerosis
    • 2880319, 20426824
    • Ferlini A, Bovolenta M, Neri M, Gualandi F, Balboni A, Yuryev A, Salvi F, Gemmati D, Liboni A, Zamboni P. Custom CGH array profiling of copy number variations (CNVs) on chromosome 6p21.32 (HLA locus) in patients with venous malformations associated with multiple sclerosis. BMC Med Genet 2010, 11:64. 2880319, 20426824.
    • (2010) BMC Med Genet , vol.11 , pp. 64
    • Ferlini, A.1    Bovolenta, M.2    Neri, M.3    Gualandi, F.4    Balboni, A.5    Yuryev, A.6    Salvi, F.7    Gemmati, D.8    Liboni, A.9    Zamboni, P.10
  • 48
    • 78349270885 scopus 로고    scopus 로고
    • The controversy of CCSVI and iron in multiple sclerosis: is ferritin the key?
    • 10.1212/WNL.0b013e3181fb44f0, 20881276
    • van Rensburg SJ, van Toorn R. The controversy of CCSVI and iron in multiple sclerosis: is ferritin the key?. Neurology 2010, 75:1581-1582. 10.1212/WNL.0b013e3181fb44f0, 20881276.
    • (2010) Neurology , vol.75 , pp. 1581-1582
    • van Rensburg, S.J.1    van Toorn, R.2
  • 49
    • 79551590477 scopus 로고    scopus 로고
    • Chronic cerebro-spinal venous insufficiency (CCSVI) and multiple sclerosis
    • 10.1007/s10072-010-0458-3, 21161309
    • Ghezzi A, Comi G, Federico A. Chronic cerebro-spinal venous insufficiency (CCSVI) and multiple sclerosis. Neurol Sci 2011, 32:17-21. 10.1007/s10072-010-0458-3, 21161309.
    • (2011) Neurol Sci , vol.32 , pp. 17-21
    • Ghezzi, A.1    Comi, G.2    Federico, A.3
  • 50
    • 79958806439 scopus 로고    scopus 로고
    • Vascular aspects of multiple sclerosis
    • 10.1016/S1474-4422(11)70105-3, 21683931
    • D'haeseleer M, Cambron M, Vanopdenbosch L, De Keyser J. Vascular aspects of multiple sclerosis. Lancet Neurol 2011, 10:657-666. 10.1016/S1474-4422(11)70105-3, 21683931.
    • (2011) Lancet Neurol , vol.10 , pp. 657-666
    • D'haeseleer, M.1    Cambron, M.2    Vanopdenbosch, L.3    De Keyser, J.4
  • 51
    • 83855163999 scopus 로고    scopus 로고
    • Pathogenic implications of iron accumulation in multiple sclerosis
    • 10.1111/j.1471-4159.2011.07536.x, 22004421
    • Williams R, Buchheit CL, Berman NE, Levine SM. Pathogenic implications of iron accumulation in multiple sclerosis. J Neurochem 2012, 120:7-25. 10.1111/j.1471-4159.2011.07536.x, 22004421.
    • (2012) J Neurochem , vol.120 , pp. 7-25
    • Williams, R.1    Buchheit, C.L.2    Berman, N.E.3    Levine, S.M.4
  • 52
    • 77957238508 scopus 로고    scopus 로고
    • Iron metabolism in macrophages from HFE hemochromatosis patients
    • 10.1016/j.ymgme.2010.07.010, 20675164
    • Jacolot S, Yang Y, Paitry P, Férec C, Mura C. Iron metabolism in macrophages from HFE hemochromatosis patients. Mol Genet Metab 2010, 101:258-267. 10.1016/j.ymgme.2010.07.010, 20675164.
    • (2010) Mol Genet Metab , vol.101 , pp. 258-267
    • Jacolot, S.1    Yang, Y.2    Paitry, P.3    Férec, C.4    Mura, C.5
  • 53
    • 77957340866 scopus 로고    scopus 로고
    • Ferroportin disease: a systematic meta-analysis of clinical and molecular findings
    • 10.1016/j.jhep.2010.05.016, 2956830, 20691492
    • Mayr R, Janecke AR, Schranz M, Griffiths WJ, Vogel W, Pietrangelo A. Ferroportin disease: a systematic meta-analysis of clinical and molecular findings. J Hepatol 2010, 53:941-949. 10.1016/j.jhep.2010.05.016, 2956830, 20691492.
    • (2010) J Hepatol , vol.53 , pp. 941-949
    • Mayr, R.1    Janecke, A.R.2    Schranz, M.3    Griffiths, W.J.4    Vogel, W.5    Pietrangelo, A.6
  • 54
    • 0033862965 scopus 로고    scopus 로고
    • HLA-DR15 is associated with lower age at onset in multiple sclerosis
    • 10.1002/1531-8249(200008)48:2<211::AID-ANA11>3.0.CO;2-R, 10939572
    • Masterman T, Ligers A, Olsson T, Andersson M, Olerup O, Hillert J. HLA-DR15 is associated with lower age at onset in multiple sclerosis. Ann Neurol 2000, 48:211-219. 10.1002/1531-8249(200008)48:2<211::AID-ANA11>3.0.CO;2-R, 10939572.
    • (2000) Ann Neurol , vol.48 , pp. 211-219
    • Masterman, T.1    Ligers, A.2    Olsson, T.3    Andersson, M.4    Olerup, O.5    Hillert, J.6
  • 55
    • 65549095185 scopus 로고    scopus 로고
    • Oligodendrocytes and myelination: the role of iron
    • 10.1002/glia.20784, 18837051
    • Todorich B, Pasquini JM, Garcia CI, Paez PM, Connor JR. Oligodendrocytes and myelination: the role of iron. Glia 2009, 57:467-478. 10.1002/glia.20784, 18837051.
    • (2009) Glia , vol.57 , pp. 467-478
    • Todorich, B.1    Pasquini, J.M.2    Garcia, C.I.3    Paez, P.M.4    Connor, J.R.5
  • 56
    • 1642281535 scopus 로고    scopus 로고
    • Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion
    • 10.1002/ana.20016, 15048884
    • Barnett MH, Prineas JW. Relapsing and remitting multiple sclerosis: pathology of the newly forming lesion. Ann Neurol 2004, 55:458-468. 10.1002/ana.20016, 15048884.
    • (2004) Ann Neurol , vol.55 , pp. 458-468
    • Barnett, M.H.1    Prineas, J.W.2
  • 59
    • 84864464223 scopus 로고    scopus 로고
    • The conundrum of iron in multiple sclerosis - time for an individualised approach
    • 10.1007/s11011-012-9290-1, 3402663, 22422107
    • van Rensburg SJ, Kotze MJ, van Toorn R. The conundrum of iron in multiple sclerosis - time for an individualised approach. Metab Brain Dis 2012, 27:239-253. 10.1007/s11011-012-9290-1, 3402663, 22422107.
    • (2012) Metab Brain Dis , vol.27 , pp. 239-253
    • van Rensburg, S.J.1    Kotze, M.J.2    van Toorn, R.3


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