Chemical phenotypes of the hmg1 and hmg2 mutants of Arabidopsis demonstrate the in-planta role of HMG-CoA reductase in triterpene biosynthesis

Chemical and Pharmaceutical Bulletin

Volumn 55, Issue 10, 2007, Pages 1518-1521

  Ohyama, Kiyoshi ^a   Suzuki, Masashi ^a   Masuda, Kazuo ^b   Yoshida, Shigeo ^a   Muranaka, Toshiya ^a,c  

^a RIKEN   (Japan)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Amyrin; Arabidopsis; HMG CoA reductase; Sterol; Synthesis; Triterpenoid

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ALPHA AMYRIN; BETA AMYRIN; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP B2 PROTEIN; LUPEOL; MEVALONIC ACID; STEROL; TRITERPENE;

ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; GENE SEQUENCE; MALE STERILITY; NONHUMAN; PHENOTYPE; PLEIOTROPY; QUANTITATIVE ANALYSIS; SENESCENCE; STANDARD;

ARABIDOPSIS; CHROMATOGRAPHY, GAS; DEUTERIUM; GENES, PLANT; HMGB1 PROTEIN; HMGB2 PROTEIN; HYDROXYMETHYLGLUTARYL COA REDUCTASES; MEVALONIC ACID; MUTATION; OLEANOLIC ACID; PHENOTYPE; STEROLS; TRITERPENES;

EID: 35648947418     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.55.1518     Document Type: Article

References (27)

1. Suzuki M., Kamide Y., Nagata N., Seki H., Ohyama K., Kato H., Masuda K., Sato S., Kato T., Tabata S., Yoshida S., Muranaka T., Plant J., 37, 750-761 (2004).
2. Kolesnikova M. D., Xiong Q., Lodeiro S., Hua L., Matsuda S. P. T., Arch. Biochem. Biophys., 447, 87-95 (2006).
3. Sawai S., Akashi T., Sakurai N., Suzuki H., Shibata D., Ayabe S., Aoki T., Plant Cell Physiol., 47, 673-677 (2006).
4. Suzuki M., Xiang T., Ohyama K., Seki H., Saito K., Muranaka T., Hayashi H., Katsube Y., Kushiro T., Shibuya M., Ebizuka Y., Plant Cell Physiol., 47, 565-571 (2006).
5. Das M. C., Mahato S. B., Phytochemistry, 22, 1071-1095 (1983).
6. Arai Y., Hirohara M., Ogawa R., Masuda K., Shiojima K., Ageta H., Chang H.-C., Chen Y.-P., Tetrahedron Lett., 37, 4381-4384 (1996).
7. Yamashita H., Masuda K., Kobayashi T., Ageta H., Shiojima K., Phytochemistry, 49, 2461-2466 (1998).
8. Xu R., Fazio G. C., Matsuda S. P. T., Phytochemistry, 65, 261-291 (2004).
9. Akihisa T., Yasukawa K., "Studies in Natural Products Chemistry (Part F)," Vol. 25, ed. by Atta-ur-Rahman, Elsevier Science Ltd., Oxford, U.K., 2001, pp. 43-87.
10. Sakurai A., Plant Phys. Biochem., 37, 351-361 (1999).
11. Fujioka S., Yokota T., Ann. Rev. Plant Biol., 54, 137-164 (2003).
12. Kohara A., Nakajima C., Hashimoto K., Ikenaga T., Tanaka H., Shoyama Y., Yoshida S., Muranaka T., Plant Mol. Biol., 57, 225-239 (2005).
13. Kasahara H., Hanada A., Kuzuyama T., Takagi M., Kamiya Y., Yamaguchi S., J. Biol. Chem., 277, 45188-45194 (2002).
14. Nagata N., Suzuki M., Yoshida S., Muranaka T., Planta, 216, 345-350 (2002).
15. Hemmerlin A., Bach T. J., Plant J., 14, 65-74 (1998).
16. Suzuki M., Muranaka T., Lipids, 42, 47-54 (2007).
17. Schaller H., Grausem B., Benveniste P., Chye M.-L., Tan C.-T., Song Y.-H., Chua N.-H., Plant Physiol., 109, 761-770 (1995).
18. Manzano D., Fernández-Busquets X., Schaller H., González V., Boronat A., Arró M., Ferrer A., Planta, 219, 982-992 (2004).
19. Learned R. M., Fink G. R., Proc. Natl. Acad. Sci. U.S.A., 86, 2779-2783 (1989).
20. Caelles C., Ferrer A., Balcells L., Hegardt F. G., Boronat A., Plant Mol. Biol., 13, 627-638 (1989).
21. Enjuto M., Balcells L., Campos N., Caelles C., Arró M., Boronat A., Proc. Natl. Acad. Sci. U.S.A., 91, 927-931 (1994).
22. Jenks M. A., Tuttle H. A., Eigenbrode S. D., Feldmann K. A., Plant Physiol., 108, 369-377 (1995).
23. Husselstein-Muller T., Schaller H., Benveniste P., Plant Mol. Biol., 45, 75-92 (2001).
24. Laurent P., Dooms C., Braekman J.-C., Daloze D., Habib-Jiwan J.-L., Rozenberg R., Termonia A., Pasteels J. M., Naturwissenschaften, 90, 524-527 (2003).
25. Shingu T., Yokoi T., Niwa M., Kikuchi T., Chem. Pharm. Bull., 21, 2252-2256 (1973).
26. Burnouf-Radosevich M., Delfel N. E., England R., Phytochemistry, 24, 2063-2066 (1985).
27. Kobayashi K., Suzuki M., Tang J., Nagata N., Ohyama K., Seki H., Kiuchi R., Kaneko Y., Nakazawa M., Matsui M., Matsumoto S., Yoshida S., Muranaka T., Plant Cell Physiol., 48, 322-331 (2007).