Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides

Environmental Health Perspectives

Volumn 120, Issue 11, 2012, Pages 1578-1584

  Orton, Frances ^a   Rosivatz, Erika ^b   Scholze, Martin ^a   Kortenkamp, Andreas ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Antiandrogen; AR antagonism; Concentration addition; Endocrine disruption; Fungicide; Mixture; Pesticide

Indexed keywords

2 HYDROXYBIPHENYL; ANDROGEN RECEPTOR; ANDROGEN RECEPTOR ANTAGONIST; ANDROSTANOLONE; CHLORPROPHAM; CYPRODINIL; DIMETHOMORPH; ENILCONAZOLE; FENHEXAMID; FLUDIOXONIL; LINURON; METHIOCARB; PESTICIDE; PIRIMIPHOS METHYL; PYRIMETHANIL; RENILLA LUCIFERIN 2 MONOOXYGENASE; TEBUCONAZOLE; UNCLASSIFIED DRUG; VINCLOZOLIN;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOTOXICITY; ENVIRONMENTAL EXPOSURE; HORMONE DETERMINATION; HUMAN; HUMAN CELL; IC 50; MDA-KB2 ASSAY; PREDICTIVE VALUE; PRIORITY JOURNAL;

ANDROGEN RECEPTOR ANTAGONISTS; CELL LINE, TUMOR; DIHYDROTESTOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; PESTICIDES; RECEPTORS, ANDROGEN; RISK ASSESSMENT;

EID: 84868597207     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1205391     Document Type: Article

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