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Angewandte Chemie - International Edition

Volumn 51, Issue 46, 2012, Pages 11606-11610

The first generation of β-galactosidase-responsive prodrugs designed for the selective treatment of solid tumors in prodrug monotherapy

(9) Legigan, Thibaut a Clarhaut, Jonathan b Tranoy Opalinski, Isabelle a Monvoisin, Arnaud a Renoux, Brigitte a Thomas, Mikaël a Le Pape, Alain c Lerondel, Stéphanie c Papot, Sébastien a

a UNIVERSITÉ DE POITIERS (France)

b POITIERS UNIVERSITY HOSPITAL (France)

c CNRS (France)

Author keywords

auristatin; cancer; galactoside; prodrugs; self immolative linkers

Indexed keywords

AURISTATIN; CANCER; GALACTOSIDE; PRODRUGS; SELF-IMMOLATIVE LINKERS;

CYTOTOXICITY;

TUMORS;

AMINOBENZOIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; AURISTATIN; BETA GALACTOSIDASE; OLIGOPEPTIDE; PRODRUG;

ANIMAL; ARTICLE; CELL SURVIVAL; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECT; ENZYMOLOGY; HUMAN; METABOLISM; MOUSE; NEOPLASM; PATHOLOGY; TUMOR CELL LINE;

AMINOBENZOATES; ANIMALS; ANTINEOPLASTIC AGENTS; BETA-GALACTOSIDASE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; HUMANS; MICE; NEOPLASMS; OLIGOPEPTIDES; PRODRUGS;

EID: 84868560034 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201204935 Document Type: Article

Times cited : (97)

References (46)

1
- 39349084237
- F. Kratz, I. A. Müller, C. Ryppa, A. Warnecke, ChemMedChem 2008, 3, 20-53.
- (2008) ChemMedChem , vol.3 , pp. 20-53
- Kratz, F.¹ Müller, I.A.² Ryppa, C.³ Warnecke, A.⁴

2
- 77955312203
- S. C. Alley, N. M. Okeley, P. D. Senter, Curr. Opin. Chem. Biol. 2010, 14, 529-537.
- (2010) Curr. Opin. Chem. Biol. , vol.14 , pp. 529-537
- Alley, S.C.¹ Okeley, N.M.² Senter, P.D.³

3
- 10744222473
- S. O. Doronina, B. E. Toki, M. Y. Torgov, B. A. Mendelsohn, C. G. Cerveny, D. F. Chace, R. L. DeBlanc, R. P. Gearing, T. D. Bovee, C. B. Siegall, J. A. Francisco, A. F. Wahl, D. L. Meyer, P. D. Senter, Nat. Biotechnol. 2003, 21, 778-784.
- (2003) Nat. Biotechnol. , vol.21 , pp. 778-784
- Doronina, S.O.¹ Toki, B.E.² Torgov, M.Y.³ Mendelsohn, B.A.⁴ Cerveny, C.G.⁵ Chace, D.F.⁶ Deblanc, R.L.⁷ Gearing, R.P.⁸ Bovee, T.D.⁹ Siegall, C.B.¹⁰ Francisco, J.A.¹¹ Wahl, A.F.¹² Meyer, D.L.¹³ Senter, P.D.¹⁴

4
- 82055176666
- L. F. Tietze, K. Schmuck, Curr. Pharm. Des. 2011, 17, 3527-3547
- (2011) Curr. Pharm. Des. , vol.17 , pp. 3527-3547
- Tietze, L.F.¹ Schmuck, K.²

5
- 1542376883
- M. Rooseboom, J. N. M. Commandeur, N. P. E. Vermeulen, Pharm. Rev. 2004, 56, 53-102.
- (2004) Pharm. Rev. , vol.56 , pp. 53-102
- Rooseboom, M.¹ Commandeur, J.N.M.² Vermeulen, N.P.E.³

6
- 0023619243
- K. D. Bagshawe, Br. J. Cancer 1987, 56, 531-532
- (1987) Br. J. Cancer , vol.56 , pp. 531-532
- Bagshawe, K.D.¹

7
- 0035980983
- P. D. Senter, C. J. Springer, Adv. Drug Delivery Rev. 2001, 53, 247-264
- (2001) Adv. Drug Delivery Rev. , vol.53 , pp. 247-264
- Senter, P.D.¹ Springer, C.J.²

8
- 33750711698
- K. D. Bagshawe, Expert Rev. Anticancer Ther. 2006, 6, 1421-1431.
- (2006) Expert Rev. Anticancer Ther. , vol.6 , pp. 1421-1431
- Bagshawe, K.D.¹

9
- 70449100441
- A. Fernandes, A. Viterisi, F. Coutrot, S. Potok, D. A. Leigh, V. Aucagne, S. Papot, Angew. Chem. 2009, 121, 6565-6569
- (2009) Angew. Chem. , vol.121 , pp. 6565-6569
- Fernandes, A.¹ Viterisi, A.² Coutrot, F.³ Potok, S.⁴ Leigh, D.A.⁵ Aucagne, V.⁶ Papot, S.⁷

10
- 70349913585
- Angew. Chem. Int. Ed. 2009, 48, 6443-6447
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 6443-6447

11
- 47649103799
- A. Kamal, V. Tekumalla, A. Krishnan, M. Pal-Bhadra, U. Bhadra, ChemMedChem 2008, 3, 794-802
- (2008) ChemMedChem , vol.3 , pp. 794-802
- Kamal, A.¹ Tekumalla, V.² Krishnan, A.³ Pal-Bhadra, M.⁴ Bhadra, U.⁵

12
- 33846578183
- M. Thomas, F. Rivault, I. Tranoy-Opalinski, J. Roche, J. P. Gesson, S. Papot, Bioorg. Med. Chem. Lett. 2007, 17, 983-986
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 983-986
- Thomas, M.¹ Rivault, F.² Tranoy-Opalinski, I.³ Roche, J.⁴ Gesson, J.P.⁵ Papot, S.⁶

13
- 0033495663
- E. Bakina, D. Farquhar, Anti-Cancer Drug Des. 1999, 14, 507-515.
- (1999) Anti-Cancer Drug Des. , vol.14 , pp. 507-515
- Bakina, E.¹ Farquhar, D.²

14
- 74149084810
- Y. Yu, L. Fang, D. Sun, Int. J. Pharm. 2010, 386, 208-215
- (2010) Int. J. Pharm. , vol.386 , pp. 208-215
- Yu, Y.¹ Fang, L.² Sun, D.³

15
- 33750107199
- L. Fang, R. F. Battisti, H. Cheng, P. Reigan, Y. Xin, J. Shen, D. Ross, K. K. Chan, E. W. Martin,- Jr., P. G. Wang, D. Sun, J. Med. Chem. 2006, 49, 6290-6297.
- (2006) J. Med. Chem. , vol.49 , pp. 6290-6297
- Fang, L.¹ Battisti, R.F.² Cheng, H.³ Reigan, P.⁴ Xin, Y.⁵ Shen, J.⁶ Ross, D.⁷ Chan, K.K.⁸ Martin Jr., E.W.⁹ Wang, P.G.¹⁰ Sun, D.¹¹

16
- 84868546274
- T. Wirth, K. Schmuck, L. F. Tietze, S. A. Sieber, Angew. Chem. 2012, 124, 2928-2931
- (2012) Angew. Chem. , vol.124 , pp. 2928-2931
- Wirth, T.¹ Schmuck, K.² Tietze, L.F.³ Sieber, S.A.⁴

17
- 84858248304
- Angew. Chem. Int. Ed. 2012, 51, 2874-2877
- (2012) Angew. Chem. Int. Ed. , vol.51 , pp. 2874-2877

18
- 79551473105
- L. F. Tietze, J. M. von-Hof, M. Müller, B. Krewer, I. Schuberth, Angew. Chem. 2010, 122, 7494-7497
- (2010) Angew. Chem. , vol.122 , pp. 7494-7497
- Tietze, L.F.¹ Von-Hof, J.M.² Müller, M.³ Krewer, B.⁴ Schuberth, I.⁵

19
- 77957331913
- Angew. Chem. Int. Ed. 2010, 49, 7336-7339
- (2010) Angew. Chem. Int. Ed. , vol.49 , pp. 7336-7339

20
- 68949213822
- L. F. Tietze, B. Krewer, Chem. Biol. Drug Des. 2009, 74, 205-211
- (2009) Chem. Biol. Drug Des. , vol.74 , pp. 205-211
- Tietze, L.F.¹ Krewer, B.²

21
- 34250363038
- L. F. Tietze, F. Major, I. Schuberth, D. A. Spiegl, B. Krewer, K. Maksimenka, G. Bringmann, J. Magull, Chem. Eur. J. 2007, 13, 4396-4409
- (2007) Chem. Eur. J. , vol.13 , pp. 4396-4409
- Tietze, L.F.¹ Major, F.² Schuberth, I.³ Spiegl, D.A.⁴ Krewer, B.⁵ Maksimenka, K.⁶ Bringmann, G.⁷ Magull, J.⁸

22
- 33749830517
- L. F. Tietze, F. Major, I. Schuberth, Angew. Chem. 2006, 118, 6724-6727
- (2006) Angew. Chem. , vol.118 , pp. 6724-6727
- Tietze, L.F.¹ Major, F.² Schuberth, I.³

23
- 33749843662
- Angew. Chem. Int. Ed. 2006, 45, 6574-6577
- (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 6574-6577

24
- 0013308228
- L. F. Tietze, T. Feuerstein, A. Fecher, F. Haunert, O. Panknin, U. Borchers, I. Schuberth, F. Alves, Angew. Chem. 2002, 114, 785-787
- (2002) Angew. Chem. , vol.114 , pp. 785-787
- Tietze, L.F.¹ Feuerstein, T.² Fecher, A.³ Haunert, F.⁴ Panknin, O.⁵ Borchers, U.⁶ Schuberth, I.⁷ Alves, F.⁸

25
- 0036495569
- Angew. Chem. Int. Ed. 2002, 41, 759-761.
- (2002) Angew. Chem. Int. Ed. , vol.41 , pp. 759-761

26
- 0036113927
- For the successful application of ADEPT, Tietze proposed the following requirements: 1)-the cytotoxic agent derived from the prodrug should achieve an IC50 value of <10-n M; and 2)-the toxicity ratio between the prodrug and the drug should exceed 1000. For more details, see.
- For the successful application of ADEPT, Tietze proposed the following requirements: 1)-the cytotoxic agent derived from the prodrug should achieve an IC50 value of <10-n M; and 2)-the toxicity ratio between the prodrug and the drug should exceed 1000. For more details, see:, L. F. Tietze, T. Herzig, T. Feuerstein, I. Schuberth, Eur. J. Org. Chem. 2002, 1634-1645.
- (2002) Eur. J. Org. Chem. , pp. 1634-1645
- Tietze, L.F.¹ Herzig, T.² Feuerstein, T.³ Schuberth, I.⁴

27
- 0001874589
- K. Bosslet, J. Czech, D. Hoffmann, Tumor Target. 1995, 1, 45-50
- (1995) Tumor Target. , vol.1 , pp. 45-50
- Bosslet, K.¹ Czech, J.² Hoffmann, D.³

28
- 0032521438
- K. Bosslet, R. Straub, M. Blumrich, J. Czech, M. Gerken, B. Sperker, H. K. Kroemer, J. P. Gesson, M. Koch, C. Monneret, Cancer Res. 1998, 58, 1195-1201.
- (1998) Cancer Res. , vol.58 , pp. 1195-1201
- Bosslet, K.¹ Straub, R.² Blumrich, M.³ Czech, J.⁴ Gerken, M.⁵ Sperker, B.⁶ Kroemer, H.K.⁷ Gesson, J.P.⁸ Koch, M.⁹ Monneret, C.¹⁰

29
- 0036080057
- S. Papot, I. Tranoy, F. Tillequin, J.-C. Florent, J.-P. Gesson, Curr. Med. Chem. Anti-Cancer Agents 2002, 2, 155-185
- (2002) Curr. Med. Chem. Anti-Cancer Agents , vol.2 , pp. 155-185
- Papot, S.¹ Tranoy, I.² Tillequin, F.³ Florent, J.-C.⁴ Gesson, J.-P.⁵

30
- 52749096860
- I. Tranoy-Opalinski, A. Fernandes, M. Thomas, J.-P. Gesson, S. Papot, Anti-Cancer Agents Med. Chem. 2008, 8, 618-637.
- (2008) Anti-Cancer Agents Med. Chem. , vol.8 , pp. 618-637
- Tranoy-Opalinski, I.¹ Fernandes, A.² Thomas, M.³ Gesson, J.-P.⁴ Papot, S.⁵

31
- 0037422066
- S. D. Conner, S. L. Schmid, Nature 2003, 422, 37-44.
- (2003) Nature , vol.422 , pp. 37-44
- Conner, S.D.¹ Schmid, S.L.²

32
- 1942503303
- H. Elnakat, M. Ratnam, Adv. Drug Delivery Rev. 2004, 56, 1067-1084.
- (2004) Adv. Drug Delivery Rev. , vol.56 , pp. 1067-1084
- Elnakat, H.¹ Ratnam, M.²

33
- 1942535110
- P. S. Low, A. C. Antony, Adv. Drug Delivery Rev. 2004, 56, 1055-1058.
- (2004) Adv. Drug Delivery Rev. , vol.56 , pp. 1055-1058
- Low, P.S.¹ Antony, A.C.²

34
- 33646385331
- D. S. Ma, C. E. Hopf, A. D. Malewicz, G. P. Donovan, P. D. Senter, W. F. Goeckeler, P. J. Maddon, W. C. Olson, Clin. Cancer Res. 2006, 12, 2591-2596
- (2006) Clin. Cancer Res. , vol.12 , pp. 2591-2596
- Ma, D.S.¹ Hopf, C.E.² Malewicz, A.D.³ Donovan, G.P.⁴ Senter, P.D.⁵ Goeckeler, W.F.⁶ Maddon, P.J.⁷ Olson, W.C.⁸

35
- 33646924550
- S. C. Jeffrey, J. B. Andreyka, S. X. Bernhardt, K. M. Kissler, T. Kline, J. S. Lenox, R. F. Moser, M. T. Nguyen, N. M. Okeley, I. J. Stone, X. Zhang, P. D. Senter, Bioconjugate Chem. 2006, 17, 831-840
- (2006) Bioconjugate Chem. , vol.17 , pp. 831-840
- Jeffrey, S.C.¹ Andreyka, J.B.² Bernhardt, S.X.³ Kissler, K.M.⁴ Kline, T.⁵ Lenox, J.S.⁶ Moser, R.F.⁷ Nguyen, M.T.⁸ Okeley, N.M.⁹ Stone, I.J.¹⁰ Zhang, X.¹¹ Senter, P.D.¹²

36
- 78650532605
- K. M. Bajjuri, Y. Liu, C. Liu, S. C. Sinha, ChemMedChem 2011, 6, 54-59.
- (2011) ChemMedChem , vol.6 , pp. 54-59
- Bajjuri, K.M.¹ Liu, Y.² Liu, C.³ Sinha, S.C.⁴

37
- 79957626584
- M. Thomas, J. Clarhaut, P.-O. Strale, I. Tranoy-Opalinski, J. Roche, S. Papot, ChemMedChem 2011, 6, 1006-1010.
- (2011) ChemMedChem , vol.6 , pp. 1006-1010
- Thomas, M.¹ Clarhaut, J.² Strale, P.-O.³ Tranoy-Opalinski, I.⁴ Roche, J.⁵ Papot, S.⁶

38
- 84857511037
- B. Renoux, T. Legigan, S. Bensalma, C. Chadeneau, J.-M. Muller, S. Papot, Org. Biomol. Chem. 2011, 9, 8459-8464
- (2011) Org. Biomol. Chem. , vol.9 , pp. 8459-8464
- Renoux, B.¹ Legigan, T.² Bensalma, S.³ Chadeneau, C.⁴ Muller, J.-M.⁵ Papot, S.⁶

39
- 84861037988
- T. Legigan, J. Clarhaut, B. Renoux, I. Tranoy-Opalinski, A. Monvoisin, J.-M. Berjeaud, F. Guilhot, S. Papot, J. Med. Chem. 2012, 55, 4516-4520.
- (2012) J. Med. Chem. , vol.55 , pp. 4516-4520
- Legigan, T.¹ Clarhaut, J.² Renoux, B.³ Tranoy-Opalinski, I.⁴ Monvoisin, A.⁵ Berjeaud, J.-M.⁶ Guilhot, F.⁷ Papot, S.⁸

40
- 80053989452
- G. M. van-Dam, G. Themelis, L. M. A. Crane, N. J. Harlaar, R. G. Pleijhuis, W. Kelder, A. Sarantopoulos, J. S. de-Jong, H. J. G. Arts, A. G. J. van-der-Zee, J. Bart, P. S. Low, V. Ntziachristos, Nat. Med. 2011, 17, 1315-1320
- (2011) Nat. Med. , vol.17 , pp. 1315-1320
- Van-Dam, G.M.¹ Themelis, G.² Crane, L.M.A.³ Harlaar, N.J.⁴ Pleijhuis, R.G.⁵ Kelder, W.⁶ Sarantopoulos, A.⁷ De-Jong, J.S.⁸ Arts, H.J.G.⁹ Van-Der-Zee, A.G.J.¹⁰ Bart, J.¹¹ Low, P.S.¹² Ntziachristos, V.¹³

41
- 77957921048
- W. Xia, P. S. Low, J. Med. Chem. 2010, 53, 6811-6824
- (2010) J. Med. Chem. , vol.53 , pp. 6811-6824
- Xia, W.¹ Low, P.S.²

42
- 67649849650
- P. S. Low, S. A. Kularatne, Curr. Opin. Chem. Biol. 2009, 13, 256-262
- (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 256-262
- Low, P.S.¹ Kularatne, S.A.²

43
- 34247249415
- J. Yang, H. Chen, I. R. Vlahov, J.-X. Cheng, P. S. Low, J. Pharmacol. Exp. Ther. 2007, 321, 462-468
- (2007) J. Pharmacol. Exp. Ther. , vol.321 , pp. 462-468
- Yang, J.¹ Chen, H.² Vlahov, I.R.³ Cheng, J.-X.⁴ Low, P.S.⁵

44
- 33748294199
- W. A. Henne, D. D. Doorneweerd, A. R. Hilgenbrink, S. A. Kularatne, P. S. Low, Bioorg. Med. Chem. Lett. 2006, 16, 5350-5355
- (2006) Bioorg. Med. Chem. Lett. , vol.16 , pp. 5350-5355
- Henne, W.A.¹ Doorneweerd, D.D.² Hilgenbrink, A.R.³ Kularatne, S.A.⁴ Low, P.S.⁵

45
- 33748792549
- J. Yang, H. Chen, I. R. Vlahov, J.-X. Cheng, P. S. Low, Proc. Natl. Acad. Sci. USA 2006, 103, 13872-13877
- (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 13872-13877
- Yang, J.¹ Chen, H.² Vlahov, I.R.³ Cheng, J.-X.⁴ Low, P.S.⁵

46
- 27944455140
- A. R. Hilgenbrink, P. S. Low, J. Pharm. Sci. 2005, 94, 2135-2146.
- (2005) J. Pharm. Sci. , vol.94 , pp. 2135-2146
- Hilgenbrink, A.R.¹ Low, P.S.²

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