Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer

EMBO Journal

Volumn 31, Issue 21, 2012, Pages 4124-4139

  Scheitz, Cornelia Johanna Franziska ^a   Lee, Tae Seung ^a   McDermitt, David James ^a   Tumbar, Tudorita ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

hair follicle; Jak Stat pathway; Runx1 AML1; squamous cell carcinoma; stem cells

Indexed keywords

4 HYDROXYTESTOSTERONE; JANUS KINASE; SHORT HAIRPIN RNA; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 3; SUPPRESSOR OF CYTOKINE SIGNALING 4; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ADENOID CYSTIC CARCINOMA; ANIMAL CELL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BASAL CELL CARCINOMA; CANCER CELL; CANCER GROWTH; CANCER REGRESSION; CELL LINEAGE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; EPITHELIUM TUMOR; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; HAIR FOLLICLE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR SIGNALING; MOUSE; MOUTH CARCINOMA; MOUTH MUCOSA; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SQUAMOUS CELL CARCINOMA; STEM CELL; TRANSCRIPTION INITIATION; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; CORE BINDING FACTOR ALPHA 2 SUBUNIT; FEMALE; HUMANS; MICE; MICE, KNOCKOUT; MOUTH NEOPLASMS; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; STAT3 TRANSCRIPTION FACTOR; STEM CELLS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; SURVIVAL RATE;

EID: 84868530288     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.270     Document Type: Article

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