Apigenin inhibits the TNFα-induced expression of eNOS and MMP-9 via modulating Akt signalling through oestrogen receptor engagement

Molecular and Cellular Biochemistry

Volumn 371, Issue 1-2, 2012, Pages 129-136

  Palmieri, Daniela ^a,b   Perego, Patrizia ^b   Palombo, Domenico ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Akt; Apigenin; Endothelial dysfunction; eNOS; MMP 9; Oestrogen receptor; TNF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APIGENIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; APIGENIN; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; MATRIX METALLOPROTEINASE 9; NITRIC OXIDE SYNTHASE TYPE III; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84868516121     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-012-1429-1     Document Type: Article

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