Developmentally-induced hypothyroidism alters the expression of Egr-1 and Arc genes and the sensitivity to cannabinoid agonists in the hippocampus. Possible implications for memory and learning

Molecular and Cellular Endocrinology

Volumn 365, Issue 1, 2013, Pages 119-128

  Giné, Elena ^a   Echeverry Alzate, Victor ^a   López Moreno, Jose Antonio ^a   López Jimenez, Alejandro ^a   Torres Romero, Daniel ^a   Perez Castillo, Ana ^b,c   Santos, Angel ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b CSIC   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Cannabinoid; Development; Hippocampus; Spatial memory; Thyroid hormone

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN; CANNABINOID 1 RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEXANABINOL; EARLY GROWTH RESPONSE FACTOR 1; LIOTHYRONINE; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARC GENE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; EGR 1 GENE; ESCAPE BEHAVIOR; GENE EXPRESSION; HIPPOCAMPUS; HYPOTHYROIDISM; IMMEDIATE EARLY GENE; LEARNING; MALE; MAZE TEST; MEMORY CONSOLIDATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SPATIAL MEMORY; TREATMENT OUTCOME;

ANIMALS; BEHAVIOR, ANIMAL; CANNABINOID RECEPTOR AGONISTS; CONGENITAL HYPOTHYROIDISM; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; DRUG RESISTANCE; EARLY GROWTH RESPONSE PROTEIN 1; ENDOCANNABINOIDS; HIPPOCAMPUS; HORMONE REPLACEMENT THERAPY; LEARNING DISORDERS; MALE; MAZE LEARNING; MEMORY DISORDERS; NERVE TISSUE PROTEINS; NEURONS; RATS; RATS, WISTAR; REACTION TIME; SPATIAL BEHAVIOR; THYROID HORMONES;

EID: 84868478195     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.10.004     Document Type: Article

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