Evidence for a specific defect in hippocampal memory in overt and subclinical hypothyroidism

Journal of Clinical Endocrinology and Metabolism

Volumn 94, Issue 10, 2009, Pages 3789-3797

  Correia, Neuman ^a   Mullally, Sinead ^b   Cooke, Gillian ^b   Tun, Tommy Kyaw ^a   Phelan, Niamh ^a   Feeney, Joanne ^b   Fitzgibbon, Maria ^b   Boran, Gerard ^a   O'Mara, Shane ^b   Gibney, James ^a  

^a ADELAIDE AND MEATH HOSPITAL   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE;

ADULT; ARTICLE; ASSOCIATIVE MEMORY; ATTENTION; BRAIN DAMAGE; CLINICAL ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; DECLARATIVE MEMORY; FEMALE; FRONTAL CORTEX; HIPPOCAMPUS; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; HYPOTHYROIDISM; INTERVENTION STUDY; MALE; NEUROPSYCHOLOGICAL TEST; OPEN STUDY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROSPECTIVE STUDY; SPATIAL MEMORY; TEACHING HOSPITAL; TEMPORAL LOBE; TREATMENT OUTCOME; VERBAL MEMORY; WORKING MEMORY;

ANIMALIA;

EID: 70349895557     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2008-2702     Document Type: Article

References (41)

1. Dugbartey AT 1998 Neurocognitive aspects of hypothyroidism. Arch Intern Med 158:1413-1418
2. Constant EL, Adam S, Seron X, Bruyer R, Seghers A, Daumerie C 2005 Anxiety and depression, attention, and executive functions in hypothyroidism. J Int Neuropsychol Soc 11:535-544 (Pubitemid 41478986)
3. Wekking EM, Appelhof BC, Fliers E, Schene AH, Huyser J, Tijssen JG, Wiersinga WM 2005 Cognitive functioning and well-being in euthyroid patients on thyroxine replacement therapy for primary hypothyroidism. Eur J Endocrinol 153:747-753 (Pubitemid 43020224)
4. Burmeister LA, Ganguli M, Dodge HH, Toczek T, DeKosky ST, Nebes RD 2001 Hypothyroidism and cognition: preliminary evidence for a specific defect in memory. Thyroid 11:1177-1185 (Pubitemid 34041899)
5. Miller KJ, Parsons TD, Whybrow PC, van Herle K, Rasgon N, van Herle A, Martinez D, Silverman DH, Bauer M 2006 Memory improvement with treatment of hypothyroidism. Int J Neurosci 116: 895-906
6. Gerges NZ, Alzoubi KH, Park CR, Diamond DM, Alkadhi KA 2004 Adverse effect of the combination of hypothyroidism and chronic psychosocial stress on hippocampus-dependent memory in rats. Behav Brain Res 155:77-84
7. Alzoubi KH, Gerges NZ, Aleisa AM, Alkadhi KA 2009 Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: behavioral, electrophysiological, and molecular studies. Hippocampus 19:66-78
8. Alzoubi KH, Gerges NZ, Alkadhi KA 2005 Levothyroxin restores hypothyroidism-induced impairment of LTP of hippocampal CA1: electrophysiological and molecular studies. Exp Neurol 195:330-341
9. Montero-Pedrazuela A, Venero C, Lavado-Autric R, Fernández-Lamo I, García-Verdugo JM, Bernal J, Guadaño-Ferraz A 2006 Modulation of adult hippocampal neurogenesis by thyroid hormones: implications in depressive-like behavior. Mol Psychiatry 11: 361-371
10. Desouza LA, Ladiwala U, Daniel SM, Agashe S, Vaidya RA, Vaidya VA 2005 Thyroid hormone regulates hippocampal neurogenesis in the adult rat brain. Mol Cell Neurosci 29:414-426 (Pubitemid 40799214)
11. Biondi B, Cooper DS 2008 The clinical significance of subclinical thyroid dysfunction. Endocr Rev 29:76-131 (Pubitemid 351252748)
12. Baldini IM, Vita A, Mauri MC, Amodei V, Carrisi M, Bravin S, Cantalamessa L 1997 Psychopathological and cognitive features in subclinical hypothyroidism. Prog Neuropsychopharmacol Biol Psychiatry 21:925-935 (Pubitemid 27410385)
13. Samuels MH, Schuff KG, Carlson NE, Carello P, Janowsky JS 2007 Health status, mood, and cognition in experimentally induced subclinical hypothyroidism. J Clin Endocrinol Metab 92:2545-2551 (Pubitemid 47037356)
14. Zhu DF, Wang ZX, Zhang DR, Pan ZL, He S, Hu XP, Chen XC, Zhou JN 2006 fMRI revealed neural substrate for reversible working memory dysfunction in subclinical hypothyroidism. Brain 129: 2923-2930 (Pubitemid 44684513)
15. Bono G, Fancellu R, Blandini F, Santoro G, Mauri M 2004 Cognitive and affective status in mild hypothyroidism and interactions with L-thyroxine treatment. Acta Neurol Scand 110:59-66 (Pubitemid 38850557)
16. Larisch R, Kley K, Nikolaus S, Sitte W, Franz M, Hautzel H, Tress W, Müller HW 2004 Depression and anxiety in different thyroid function states. Horm Metab Res 36:650-653 (Pubitemid 39457644)
17. Nelson H 1982 National adult reading test (NART): For the assessment of premorbid intelligence in patients with dementia. Glasgow, UK: NFER-NELSON Publishing Company, Limited
18. Zigmond AS, Snaith RP 1983 The hospital anxiety and depression scale. Acta Psychiatr Scand 67:361-370
19. Rey A 1941 L'examen psychologique dans les cas d'encéphalopathie traumatique. Archives de Psychologie 28:215-285
20. Shin MS, Park SY, Park SR, Seol SH, Kwon JS 2006 Clinical and empirical applications of the Rey-Osterrieth Complex Figure Test. Nat Protoc 1:892-899
21. Spreen OSE 1998 A compendum of neuropsychological tests. 2nd ed. New York: Oxford University Press
22. Lezak MD 1995 Neuropsychological assessment. New York: Oxford University Press
23. Hubley AM, Jassal S 2006 Comparability of the Rey-Osterrieth and Modified Taylor Complex Figures using total scores, completion times, and construct validation. J Clin Exp Neuropsychol 28:1482-1497 (Pubitemid 44578251)
24. Wilson BA, Baddeley AD, Cockburn JM 1989 How do old dogs learn new tricks: teaching a technological skill to brain injured people. Cortex 25:115-119
25. Parkin AJ, Leng NRC 1993 Neuropsychology of the amnesic syndrome. Brighton, UK: Psychology Press
26. Zeineh MM, Engel SA, Thompson PM, Bookheimer SY 2003 Dynamics of the hippocampus during encoding and retrieval of facename pairs. Science 299:577-580 (Pubitemid 36135158)
27. Meyer-Lindenberg A, Poline JB, Kohn PD, Holt JL, Egan MF, Weinberger DR, Berman KF 2001 Evidence for abnormal cortical functional connectivity during working memory in schizophrenia. Am J Psychiatry 158:1809-1817 (Pubitemid 33054773)
28. Goldman-Rakic PS 1996 The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive. Philos Trans R Soc Lond B Biol Sci 351:1445-1453
29. Jonides J, Smith EE, Lauber EJ, Awh E, Minoshima S, Koeppe RA 1997 Verbal working memory load affects regional brain activation as measured by PET. J Cogn Neurosci 9:462-475 (Pubitemid 27338899)
30. Smith EE, Jonides J 1998 Neuroimaging analyses of human working memory. Proc Natl Acad Sci USA 95:12061-12068 (Pubitemid 28460539)
31. Stroop J 1935 Studies of interference in series verbal reactions. J Exper Psychol 18:643-662
32. Carter CS, van Veen V 2007 Anterior cingulate cortex and conflict detection: an update of theory and data. Cogn Affect Behav Neurosci 7:367-379
33. Tabachnick BG, Fidell L 2007 Using multivariate statistics. 5th ed. Boston: Pearson Education
34. Reid RE, Kim EM, Page D, O'Mara SM, O'Hare E 2007 Thyroxine replacement in an animal model of congenital hypothyroidism. Physiol Behav 91:299-303 (Pubitemid 46770810)
35. Samuels MH, Schuff KG, Carlson NE, Carello P, Janowsky JS 2007 Health status, psychological symptoms, mood, and cognition in L-thyroxine-treated hypothyroid subjects. Thyroid 17:249-258 (Pubitemid 46557374)
36. Jorde R, Waterloo K, Storhaug H, Nyrnes A, Sundsfjord J, Jenssen TG 2006 Neuropsychological function and symptoms in subjects with subclinical hypothyroidism and the effect of thyroxine treatment. J Clin Endocrinol Metab 91:145-153 (Pubitemid 43069130)
37. Bohbot VD, Kalina M, Stepankova K, Spackova N, Petrides M, Nadel L 1998 Spatial memory deficits in patients with lesions to the right hippocampus and to the right parahippocampal cortex. Neuropsychologia 36:1217-1238 (Pubitemid 28529541)
38. Miller KJ, Parsons TD, Whybrow PC, Van Herle K, Rasgon N, Van Herle A, Martinez D, Silverman DH, Bauer M 2007 Verbal memory retrieval deficits associated with untreated hypothyroidism. J Neuropsychiatry Clin Neurosci 19:132-136 (Pubitemid 46649635)
39. Davis JD, Tremont G 2007 Neuropsychiatric aspects of hypothyroidism and treatment reversibility. Minerva Endocrinol 32: 49-65
40. Ambrogini P, Cuppini R, Ferri P, Mancini C, Ciaroni S, Voci A, Gerdoni E, Gallo G 2005 Thyroid hormones affect neurogenesis in the dentate gyrus of adult rat. Neuroendocrinology 81:244-253 (Pubitemid 41397032)
41. Kopelman MD 2002 Disorders of memory. Brain 125:2152-2190