Adenovirus vector-mediated expression of TMEM166 inhibits human cancer cell growth by autophagy and apoptosis in vitro and in vivo

Cancer Letters

Volumn 328, Issue 1, 2013, Pages 126-134

  Chang, Ying ^a,b   Li, Yanjun ^a,b   Hu, Jia ^a,b   Guo, Jinhai ^c   Xu, Dong ^a,b   Xie, Hong ^a   Lv, Xiaodong ^a   Shi, Taiping ^c   Chen, Yingyu ^a,b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY   (China)

^c CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

Author keywords

Adenovirus vector; Anti tumor activity; Apoptosis; Autophagy; TMEM166

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; CASPASE 3; MAMMALIAN TARGET OF RAPAMYCIN; MEMBRANE PROTEIN; S6 KINASE; TRANSMEMBRANE PROTEIN 166; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CANCER INHIBITION; CANCER TISSUE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME ACTIVATION; EXPRESSION VECTOR; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT NEOPLASTIC DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; FEMALE; GENETIC THERAPY; GENETIC VECTORS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, NUDE; NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

ADENOVIRIDAE; HUMAN ADENOVIRUS TYPE 5;

EID: 84868471830     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.08.032     Document Type: Article

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