Evaluation of hepatic glucose metabolism via gluconeogenesis and glycogenolysis after oral administration of insulin nanoparticles

Drug Development and Industrial Pharmacy

Volumn 38, Issue 12, 2012, Pages 1441-1450

  Woitiski, Camile B ^a   Neufeld, Ronald J ^b   Soares, Ana F ^c   Figueiredo, Isabel V ^a   Veiga, Francisco J ^a   Carvalho, Rui A ^c,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b QUEEN S UNIVERSITY   (Canada)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

hepatic metabolism; histopathological analysis; Insulin; nanoparticles; oral delivery

Indexed keywords

DEXTRAN SULFATE; INSULIN; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATOMIC FORCE MICROSCOPY; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLYCOGENOLYSIS; HISTOPATHOLOGY; INSULIN TREATMENT; INTESTINE; KIDNEY; LIVER; LIVER METABOLISM; MALE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS; PARTICLE SIZE; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SPLEEN; STREPTOZOCIN DIABETES; TRANSMISSION ELECTRON MICROSCOPY;

ADMINISTRATION, ORAL; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; GLUCONEOGENESIS; GLUCOSE; GLYCOGENOLYSIS; HYPOGLYCEMIC AGENTS; INSULIN; INTESTINAL ABSORPTION; LIVER; MALE; NANOPARTICLES; RATS; RATS, WISTAR;

EID: 84868371710     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2011.653789     Document Type: Article

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