IPTG limitation avoids metabolic burden and acetic acid accumulation in induced fed-batch cultures of Escherichia coli M15 under glucose limiting conditions

Biochemical Engineering Journal

Volumn 70, Issue , 2013, Pages 78-83

  Lecina, Martí ^a   Sarró, Enric ^a   Casablancas, Antoni ^a   Gòdia, Francesc ^a   Cairó, Jordi J ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Acetic acid accumulation; Bioprocess design; Escherichia coli; Fed batch culture; IPTG limitation; Substrate limitation

Indexed keywords

BIOPROCESS DESIGN; BIOPROCESSES; COMMON STRATEGY; E. COLI; EXPRESSION VECTORS; FED-BATCH CULTURES; HIGH CELL DENSITY; HIGH CELL DENSITY CULTURES; IPTG LIMITATION; LIMITING CONDITION; PROTEIN EXPRESSIONS; PROTEIN PRODUCTION; SPECIFIC GROWTH RATE; SUBSTRATE LIMITATION; VOLUMETRIC PRODUCTIVITY;

ACETIC ACID; BATCH CELL CULTURE; GLUCOSE; METABOLISM; PH; PHYSIOLOGY; RECOMBINANT PROTEINS;

ESCHERICHIA COLI;

ACETIC ACID; BACTERIAL PROTEIN; GLUCOSE;

ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BIOPROCESS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COST CONTROL; ESCHERICHIA COLI; FED BATCH CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VOLUMETRY;

ESCHERICHIA COLI;

EID: 84868324306     PISSN: 1369703X     EISSN: 1873295X     Source Type: Journal    
DOI: 10.1016/j.bej.2012.10.006     Document Type: Article

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