Docking protein Gab2 regulates mucin expression and goblet cell hyperplasia through TYK2/STAT6 pathway

FASEB Journal

Volumn 26, Issue 11, 2012, Pages 4603-4613

  Zhang, Xue ^a,b   Zhang, Yun ^a,b   Tao, Bo ^a,b   Wang, Di ^c   Cheng, Hongqiang ^a,b   Wang, Kai ^d   Zhou, Ren ^a,b   Xie, Qiangmin ^d   Ke, Yuehai ^a,b,d  

^a Department of Pathology and Pathophysiology ^*  (China)

^b Program in Molecular Cell Biology   (China)

^c Institute of Immunology   (China)

^d ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Airway epithelial cells; Airway inflammatory diseases; IL 13; Muc5ac; SOCS3

Indexed keywords

DOCKING PROTEIN; DOCKING PROTEIN GAB2; INTERLEUKIN 13; MUCIN; OVALBUMIN; PROTEIN KINASE TYK2; STAT6 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL HYPERPLASIA; CELL PROLIFERATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GOBLET CELL; GOBLET CELL HYPERPLASIA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG CANCER; LUNG LAVAGE; MOUSE; MUCUS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; SENSITIZATION; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; GOBLET CELLS; HUMANS; HYPERPLASIA; HYPERSENSITIVITY; INTERLEUKIN-13; LUNG; LUNG NEOPLASMS; MICE; MICE, KNOCKOUT; MUCINS; MUCUS; OVALBUMIN; PHOSPHOPROTEINS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; STAT6 TRANSCRIPTION FACTOR; TYK2 KINASE;

MUS;

EID: 84868285121     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-211755     Document Type: Article

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