Ruthenium arene complexes as HIV-1 integrase strand transfer inhibitors

Journal of Inorganic Biochemistry

Volumn 118, Issue , 2013, Pages 74-82

  Carcelli, Mauro ^a   Bacchi, Alessia ^a   Pelagatti, Paolo ^a   Rispoli, Gabriele ^a   Rogolino, Dominga ^a   Sanchez, Tino W ^c   Sechi, Mario ^b   Neamati, Nouri ^c  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF SASSARI   (Italy)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

HIV integrase; Metal complex; Ru complex; Strand transfer inhibitor

Indexed keywords

6 BENZYL 1 (2 HYDROXYETHYL) 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXYLATE ETHYL ESTER; 6 BENZYL 1 (2 HYDROXYETHYL) 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXYLIC ACID; ELVITEGRAVIR; INTEGRASE INHIBITOR; N (4 FLUOROBENZYL) 5 HYDROXY 1 METHYL 2 [1 METHYL 1 [[(5 METHYL 1,3,4 OXADIAZOL 2 YL)CARBONYL]AMINO]ETHYL] 6 OXO 1,6 DIHYDROPYRIMIDINE 4 CARBOXAMIDE; RALTEGRAVIR; RUTHENIUM COMPLEX; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CATALYSIS; CONCENTRATION (PARAMETERS); CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; ENZYMATIC ASSAY; X RAY DIFFRACTION;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; DNA, VIRAL; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV-1; HUMANS; MCF-7 CELLS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; ORGANOMETALLIC COMPOUNDS; PYRROLIDINONES; QUINOLONES; RUTHENIUM;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84868239291     PISSN: 01620134     EISSN: 18733344     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2012.09.021     Document Type: Article

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