The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 3, 2008, Pages 901-908

  Garvey, Edward P ^a   Johns, Brian A ^a   Gartland, Margaret J ^a   Foster, Scott A ^a   Miller, Wayne H ^a   Ferris, Robert G ^a   Hazen, Richard J ^a   Underwood, Mark R ^a   Boros, Eric E ^a   Thompson, James B ^a   Weatherhead, Jason G ^a   Koble, Cecilia S ^a   Allen, Scott H ^a   Schaller, Lee T ^a   Sherrill, Ronald G ^a   Yoshinaga, Tomokazu ^b   Kobayashi, Masanori ^b   Wakasa Morimoto, Chiaki ^b   Miki, Shigeru ^b   Nakahara, Koichiro ^b   Noshi, Takeshi ^b   Sato, Akihiko ^b   Fujiwara, Tamio ^b   more..

^a GLAXOSMITHKLINE   (United States)

^b SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ADEFOVIR; AMPRENAVIR; ATAZANAVIR; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ENFUVIRTIDE; GSK 304649; GSK 364735; INDINAVIR; INTEGRASE INHIBITOR; LAMIVUDINE; LOPINAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE; RIBAVIRIN; RITONAVIR; RNA DIRECTED DNA POLYMERASE; SAQUINAVIR; STAVUDINE; TENOFOVIR; UNCLASSIFIED DRUG; ZALCITABINE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CELL ASSAY; CONTROLLED STUDY; DNA INTEGRATION; DRUG POTENTIATION; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROPHOBICITY; IC 50; LONG TERMINAL REPEAT; METAL BINDING; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; VIRUS REPLICATION; VIRUS RESISTANCE;

ANTI-HIV AGENTS; CELL LINE; CELLS, CULTURED; DRUG RESISTANCE, VIRAL; DRUG SYNERGISM; HIV INTEGRASE; HIV INTEGRASE INHIBITORS; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; MICROBIAL SENSITIVITY TESTS; MUTATION; NAPHTHYRIDINES; REVERSE TRANSCRIPTASE INHIBITORS; VIRUS INTEGRATION; VIRUS REPLICATION;

EID: 40549145842     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01218-07     Document Type: Article

References (32)