Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: Role of nonstructural component 5A and CCAAT/enhancer-binding protein β

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 37340-37351

  Qadri, Ishtiaq ^a,e   Choudhury, Mahua ^a   Rahman, Shaikh Mizanoor ^a   Knotts, Trina A ^a,f   Janssen, Rachel C ^a   Schaack, Jerome ^b   Iwahashi, Mieko ^c   Puljak, Livia ^d,g   Simon, Francis R ^c   Kilic, Gordan ^d   Fitz, Gregory ^d   Friedman, Jacob E ^a,c  

^a Children's Hospital Colorado   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^f AGRICULTURAL RESEARCH SERVICE   (United States)

^g UNIVERSITY OF SPLIT   (Croatia)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION; VIRUSES;

CCAAT/ENHANCER-BINDING PROTEINS; CHRONIC HEPATITIS C; GLUCONEOGENESIS; HEPATIC STEATOSIS; HEPATITIS C VIRUS; NON-STRUCTURAL COMPONENTS; PHOSPHOENOLPYRUVATE CARBOXYKINASE; TYPE-2 DIABETES;

PROTEINS;

APOLIPOPROTEIN B; CCAAT ENHANCER BINDING PROTEIN BETA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FORKHEAD BOX PROTEIN O1; FORKHEAD TRANSCRIPTION FACTOR; GLUCOSE; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LIVER X RECEPTOR ALPHA; NONSTRUCTURAL PROTEIN 5A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PROTEIN KINASE B; SHORT HAIRPIN RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL VACUOLE; CONTROLLED STUDY; ENZYME ACTIVATION; FATTY LIVER; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; HEPATITIS C VIRUS; INSULIN RESISTANCE; INSULIN RESPONSE; LIPID STORAGE; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPLICON; RNA INTERFERENCE; UPREGULATION; VIRUS GENOME; VIRUS REPLICATION;

EID: 84868236550     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.384743     Document Type: Article

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