In vitro activity of human translation initiation factor eIF4B is not affected by phosphomimetic amino acid substitutions S422D and S422E

Biochimie

Volumn 94, Issue 12, 2012, Pages 2484-2490

  Shagam, Lev I ^a   Terenin, Ilya M ^a   Andreev, Dmitri E ^a   Dunaevsky, Jacov E ^a   Dmitriev, Sergey E ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

48S complex reconstitution; Eukaryotic translation initiation factor eIF4B; Phosphorylation; PIK3 mTOR signaling pathway; Ser422Asp; Ser422Glu

Indexed keywords

AMINO ACID; INITIATION FACTOR; RECOMBINANT PROTEIN; TRANSLATION INITIATION FACTOR EIF4B; UNCLASSIFIED DRUG; EIF-4B; INITIATION FACTOR 4B; MITOGENIC AGENT; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; FEMALE; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; PLASMID; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; AMINO ACID SEQUENCE; CELL FREE SYSTEM; DRUG EFFECT; GENETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN SYNTHESIS; RIBOSOME; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

EUKARYOTA; MAMMALIA;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL-FREE SYSTEM; EUKARYOTIC INITIATION FACTORS; HELA CELLS; HUMANS; MITOGENS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RIBOSOMES; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SIGNAL TRANSDUCTION;

EID: 84868210924     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.06.021     Document Type: Article

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