메뉴 건너뛰기




Volumn 24, Issue 6, 2012, Pages 672-678

Effect of cancer therapy on neural stem cells: Implications for cognitive function

Author keywords

cancer; chemotherapy; cognition; neural stem cells; radiation

Indexed keywords

APOLIPOPROTEIN E; CATECHOL METHYLTRANSFERASE; CYCLOPHOSPHAMIDE; DOPAMINE; DOXORUBICIN; FLUOROURACIL; METHOTREXATE; TAMOXIFEN;

EID: 84868193462     PISSN: 10408746     EISSN: 1531703X     Source Type: Journal    
DOI: 10.1097/CCO.0b013e3283571a8e     Document Type: Review
Times cited : (41)

References (69)
  • 1
    • 84868208402 scopus 로고    scopus 로고
    • Cancer Facts and Figures 2012
    • American Cancer Society
    • American Cancer Society. Cancer Facts and Figures 2012. Atlanta: American Cancer Society; 2012.
    • (2012) Atlanta: American Cancer Society
  • 2
    • 74749089506 scopus 로고    scopus 로고
    • Challenges after curative treatment for childhood cancer and long-term follow up of survivors
    • Oeffinger KC, Nathan PC, Kremer LC. Challenges after curative treatment for childhood cancer and long-term follow up of survivors. Hematol Oncol Clin North Am 2010; 24:129-149.
    • (2010) Hematol Oncol Clin North Am , vol.24 , pp. 129-149
    • Oeffinger, K.C.1    Nathan, P.C.2    Kremer, L.C.3
  • 3
    • 67649660035 scopus 로고    scopus 로고
    • Long-term outcomes among adult survivors of childhood central nervous system malignancies in the Childhood Cancer Survivor Study
    • Armstrong GT, Liu Q, Yasui Y, et al. Long-term outcomes among adult survivors of childhood central nervous system malignancies in the Childhood Cancer Survivor Study. J Natl Cancer Inst 2009; 101:946-958.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 946-958
    • Armstrong, G.T.1    Liu, Q.2    Yasui, Y.3
  • 4
    • 0036246195 scopus 로고    scopus 로고
    • CNS late-effects after ALL therapy in childhood. Part III. Neuropsychological performance in long-term survivors of childhood ALL: Impairments of concentration, attention, and memory
    • Langer T, Martus P, Ottensmeier H, et al. CNS late-effects after ALL therapy in childhood. Part III. Neuropsychological performance in long-term survivors of childhood ALL: impairments of concentration, attention, and memory. Med Pediatr Oncol 2002; 38:320-328.
    • (2002) Med Pediatr Oncol , vol.38 , pp. 320-328
    • Langer, T.1    Martus, P.2    Ottensmeier, H.3
  • 5
    • 78650109406 scopus 로고    scopus 로고
    • Region-specific radiotherapy and neuropsychological outcomes in adult survivors of childhood CNS malignancies
    • Armstrong GT, Jain N, Liu W, et al. Region-specific radiotherapy and neuropsychological outcomes in adult survivors of childhood CNS malignancies. Neuro Oncol 2010; 12:1173-1186.
    • (2010) Neuro Oncol , vol.12 , pp. 1173-1186
    • Armstrong, G.T.1    Jain, N.2    Liu, W.3
  • 6
    • 0001862032 scopus 로고
    • The myelogenetic cycles of regional maturation of the brain
    • Minkowski A editor Oxford: Blackwell Scientific Publications
    • Yakovlev P. The myelogenetic cycles of regional maturation of the brain. In: Minkowski A, editor. Regional development of the brain in early life. Oxford: Blackwell Scientific Publications; 1967. pp. 3-70.
    • (1967) Regional Development of the Brain in Early Life , pp. 3-70
    • Yakovlev, P.1
  • 7
    • 0024848897 scopus 로고
    • Myelination of cortical-hippocampal relays during late adolescence
    • Benes FM. Myelination of cortical-hippocampal relays during late adolescence. Schizophr Bull 1989; 15:585-593.
    • (1989) Schizophr Bull , vol.15 , pp. 585-593
    • Benes, F.M.1
  • 8
    • 80051791344 scopus 로고    scopus 로고
    • Long-term neurocognitive outcomes in young adult survivors of childhood acute lymphoblastic leukemia
    • Edelstein K, D'Agostino N, Bernstein LJ, et al. Long-term neurocognitive outcomes in young adult survivors of childhood acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2011; 33:450-458.
    • (2011) J Pediatr Hematol Oncol , vol.33 , pp. 450-458
    • Edelstein, K.1    D'Agostino, N.2    Bernstein, L.J.3
  • 9
    • 84857833085 scopus 로고    scopus 로고
    • Neuropsychological outcomes of standard risk and high risk patients treated for acute lymphoblastic leukemia on Dana-Farber ALL consortium protocol 95-01 at 5 years postdiagnosis
    • Waber DP, Queally JT, Catania L, et al. Neuropsychological outcomes of standard risk and high risk patients treated for acute lymphoblastic leukemia on Dana-Farber ALL consortium protocol 95-01 at 5 years postdiagnosis. Pediatr Blood Cancer 2011; 58:758-765.
    • (2011) Pediatr Blood Cancer , vol.58 , pp. 758-765
    • Waber, D.P.1    Queally, J.T.2    Catania, L.3
  • 10
    • 77649098538 scopus 로고    scopus 로고
    • Working memory in survivors of childhood acute lymphocytic leukemia: Functional neuroimaging analyses
    • Robinson KE, Livesay KL, Campbell LK, et al. Working memory in survivors of childhood acute lymphocytic leukemia: functional neuroimaging analyses. Pediatr Blood Cancer 2010; 54:585-590.
    • (2010) Pediatr Blood Cancer , vol.54 , pp. 585-590
    • Robinson, K.E.1    Livesay, K.L.2    Campbell, L.K.3
  • 11
    • 0024504664 scopus 로고
    • Effects of radiation therapy on neuropsychological functioning in patients with nasopharyngeal carcinoma
    • Lee PW, Hung BK, Woo EK, et al. Effects of radiation therapy on neuropsychological functioning in patients with nasopharyngeal carcinoma. J Neurol Neurosurg Psychiatry 1989; 52:488-492.
    • (1989) J Neurol Neurosurg Psychiatry , vol.52 , pp. 488-492
    • Lee, P.W.1    Hung, B.K.2    Woo, E.K.3
  • 12
    • 10344263377 scopus 로고    scopus 로고
    • Pathogenesis of irradiation-induced cognitive dysfunction
    • Abayomi OK. Pathogenesis of irradiation-induced cognitive dysfunction. Acta Oncol 1996; 35:659-663.
    • (1996) Acta Oncol , vol.35 , pp. 659-663
    • Abayomi, O.K.1
  • 13
    • 0028356814 scopus 로고
    • Neurobehavioral sequelae of cranial irradiation in adults: A review of radiation-induced encephalopathy
    • Crossen JR, Garwood D, Glatstein E, Neuwelt EA. Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy. J Clin Oncol 1994; 12:627-642.
    • (1994) J Clin Oncol , vol.12 , pp. 627-642
    • Crossen, J.R.1    Garwood, D.2    Glatstein, E.3    Neuwelt, E.A.4
  • 14
    • 0035933187 scopus 로고    scopus 로고
    • Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients
    • Surma-aho O, Niemela M, Vilkki J, et al. Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients. Neurology 2001; 56:1285-1290.
    • (2001) Neurology , vol.56 , pp. 1285-1290
    • Surma-Aho, O.1    Niemela, M.2    Vilkki, J.3
  • 15
    • 79959558529 scopus 로고    scopus 로고
    • International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in patients with cancer
    • Wefel JS, Vardy J, Ahles T, Schagen SB. International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in patients with cancer. Lancet Oncol 2011; 12:703-708.
    • (2011) Lancet Oncol , vol.12 , pp. 703-708
    • Wefel, J.S.1    Vardy, J.2    Ahles, T.3    Schagen, S.B.4
  • 16
    • 0026568820 scopus 로고
    • Cognitive functioning in cancer patients: Effect of previous treatment
    • Meyers CA, Abbruzzese JL. Cognitive functioning in cancer patients: effect of previous treatment. Neurology 1992; 42:434-436.
    • (1992) Neurology , vol.42 , pp. 434-436
    • Meyers, C.A.1    Abbruzzese, J.L.2
  • 17
    • 81355154161 scopus 로고    scopus 로고
    • Prefrontal cortex and executive function impairments in primary breast cancer
    • Kesler SR, Kent JS, O'Hara R. Prefrontal cortex and executive function impairments in primary breast cancer. Arch Neurol 2011; 68:1447-1453.
    • (2011) Arch Neurol , vol.68 , pp. 1447-1453
    • Kesler, S.R.1    Kent, J.S.2    O'Hara, R.3
  • 18
    • 79960131410 scopus 로고    scopus 로고
    • Cerebral hyporesponsiveness and cognitive impairment 10 years after chemotherapy for breast cancer
    • De Ruiter MB, Reneman L, Boogerd W, et al. Cerebral hyporesponsiveness and cognitive impairment 10 years after chemotherapy for breast cancer. Hum Brain Mapp 2011; 32:1206-1219.
    • (2011) Hum Brain Mapp , vol.32 , pp. 1206-1219
    • De Ruiter, M.B.1    Reneman, L.2    Boogerd, W.3
  • 19
    • 84863752197 scopus 로고    scopus 로고
    • Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy
    • Koppelmans V, Breteler MM, Boogerd W, et al. Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy. J Clin Oncol 2012; 30:1080-1086.
    • (2012) J Clin Oncol , vol.30 , pp. 1080-1086
    • Koppelmans, V.1    Breteler, M.M.2    Boogerd, W.3
  • 20
    • 84864056178 scopus 로고    scopus 로고
    • The impact of chemotherapy on cognitive outcomes in adults with primary brain tumors
    • Abrey LE. The impact of chemotherapy on cognitive outcomes in adults with primary brain tumors. J Neurooncol 2012; 108:285-290.
    • (2012) J Neurooncol , vol.108 , pp. 285-290
    • Abrey, L.E.1
  • 21
    • 2442649323 scopus 로고    scopus 로고
    • The cognitive sequelae of standarddose adjuvant chemotherapy in women with breast carcinoma: Results of a prospective, randomized, longitudinal trial
    • Wefel JS, Lenzi R, Theriault RL, et al. The cognitive sequelae of standarddose adjuvant chemotherapy in women with breast carcinoma: results of a prospective, randomized, longitudinal trial. Cancer 2004; 100:2292-2299.
    • (2004) Cancer , vol.100 , pp. 2292-2299
    • Wefel, J.S.1    Lenzi, R.2    Theriault, R.L.3
  • 22
    • 34547840273 scopus 로고    scopus 로고
    • Cognitive functions in primary central nervous system lymphoma: Literature review and assessment guidelines
    • Correa DD, Maron L, Harder H, et al. Cognitive functions in primary central nervous system lymphoma: literature review and assessment guidelines. Ann Oncol 2007; 18:1145-1151.
    • (2007) Ann Oncol , vol.18 , pp. 1145-1151
    • Correa, D.D.1    Maron, L.2    Harder, H.3
  • 23
    • 34247619659 scopus 로고    scopus 로고
    • Cognitive function during neoadjuvant chemotherapy for breast cancer: Results of a prospective, multicenter, longitudinal study
    • Hermelink K, Untch M, Lux MP, et al. Cognitive function during neoadjuvant chemotherapy for breast cancer: results of a prospective, multicenter, longitudinal study. Cancer 2007; 109:1905-1913.
    • (2007) Cancer , vol.109 , pp. 1905-1913
    • Hermelink, K.1    Untch, M.2    Lux, M.P.3
  • 24
    • 74849097394 scopus 로고    scopus 로고
    • Inhibition of hippocampal cell proliferation by methotrexate in rats is not potentiated by the presence of a tumor
    • Seigers R, Pourtau L, Schagen SB, et al. Inhibition of hippocampal cell proliferation by methotrexate in rats is not potentiated by the presence of a tumor. Brain Res Bull 2010; 81:472-476.
    • (2010) Brain Res Bull , vol.81 , pp. 472-476
    • Seigers, R.1    Pourtau, L.2    Schagen, S.B.3
  • 25
    • 0028364703 scopus 로고
    • Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
    • Cameron HA, Gould E. Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience 1994; 61:203-209.
    • (1994) Neuroscience , vol.61 , pp. 203-209
    • Cameron, H.A.1    Gould, E.2
  • 26
    • 0026646239 scopus 로고
    • Adrenal hormones suppress cell division in the adult rat dentate gyrus
    • Gould E, Cameron HA, Daniels DC, et al. Adrenal hormones suppress cell division in the adult rat dentate gyrus. J Neurosci 1992; 12:3642-3650.
    • (1992) J Neurosci , vol.12 , pp. 3642-3650
    • Gould, E.1    Cameron, H.A.2    Daniels, D.C.3
  • 27
    • 58149293617 scopus 로고    scopus 로고
    • Cognitive effects of tamoxifen in premenopausal women with breast cancer compared to healthy controls
    • Palmer JL, Trotter T, Joy AA, Carlson LE. Cognitive effects of tamoxifen in premenopausal women with breast cancer compared to healthy controls. J Cancer Surviv 2008; 2:275-282.
    • (2008) J Cancer Surviv , vol.2 , pp. 275-282
    • Palmer, J.L.1    Trotter, T.2    Joy, A.A.3    Carlson, L.E.4
  • 28
    • 77950475217 scopus 로고    scopus 로고
    • Effects of tamoxifen and exemestane on cognitive functioning of postmenopausal patients with breast cancer: Results from the neuropsychological side study of the tamoxifen and exemestane adjuvant multinational trial
    • Schilder CM, Seynaeve C, Beex LV, et al. Effects of tamoxifen and exemestane on cognitive functioning of postmenopausal patients with breast cancer: results from the neuropsychological side study of the tamoxifen and exemestane adjuvant multinational trial. J Clin Oncol 2010; 28:1294-1300.
    • (2010) J Clin Oncol , vol.28 , pp. 1294-1300
    • Schilder, C.M.1    Seynaeve, C.2    Beex, L.V.3
  • 29
    • 0042695788 scopus 로고    scopus 로고
    • The relationship of APOE genotype to neuropsychological performance in long-term cancer survivors treated with standard dose chemotherapy
    • Ahles TA, Saykin AJ, Noll WW, et al. The relationship of APOE genotype to neuropsychological performance in long-term cancer survivors treated with standard dose chemotherapy. Psychooncology 2003; 12:612-619.
    • (2003) Psychooncology , vol.12 , pp. 612-619
    • Ahles, T.A.1    Saykin, A.J.2    Noll, W.W.3
  • 30
    • 79952834173 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors
    • Small BJ, Rawson KS, Walsh E, et al. Catechol-O-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors. Cancer 2011; 117:1369-1376.
    • (2011) Cancer , vol.117 , pp. 1369-1376
    • Small, B.J.1    Rawson, K.S.2    Walsh, E.3
  • 31
    • 51649089891 scopus 로고    scopus 로고
    • Screening for neurocognitive impairment in pediatric cancer long-term survivors
    • Krull KR, Okcu MF, Potter B, et al. Screening for neurocognitive impairment in pediatric cancer long-term survivors. J Clin Oncol 2008; 26:4138-4143.
    • (2008) J Clin Oncol , vol.26 , pp. 4138-4143
    • Krull, K.R.1    Okcu, M.F.2    Potter, B.3
  • 32
    • 79960174296 scopus 로고    scopus 로고
    • Folate pathway polymorphisms predict deficits in attention and processing speed after childhood leukemia therapy
    • Kamdar KY, Krull KR, El-Zein RA, et al. Folate pathway polymorphisms predict deficits in attention and processing speed after childhood leukemia therapy. Pediatr Blood Cancer 2011; 57:454-460.
    • (2011) Pediatr Blood Cancer , vol.57 , pp. 454-460
    • Kamdar, K.Y.1    Krull, K.R.2    El-Zein, R.A.3
  • 33
    • 0032471333 scopus 로고    scopus 로고
    • White matter disease induced by high-dose chemotherapy: Longitudinal study with MR imaging and proton spectroscopy
    • Brown MS, Stemmer SM, Simon JH, et al. White matter disease induced by high-dose chemotherapy: longitudinal study with MR imaging and proton spectroscopy. AJNR Am J Neuroradiol 1998; 19:217-221.
    • (1998) AJNR Am J Neuroradiol , vol.19 , pp. 217-221
    • Brown, M.S.1    Stemmer, S.M.2    Simon, J.H.3
  • 34
    • 0027934647 scopus 로고
    • White matter changes in patients with breast cancer treated with high-dose chemotherapy and autologous bone marrow support
    • Stemmer SM, Stears JC, Burton BS, et al. White matter changes in patients with breast cancer treated with high-dose chemotherapy and autologous bone marrow support. AJNR Am J Neuroradiol 1994; 15:1267-1273.
    • (1994) AJNR Am J Neuroradiol , vol.15 , pp. 1267-1273
    • Stemmer, S.M.1    Stears, J.C.2    Burton, B.S.3
  • 35
    • 84855945935 scopus 로고    scopus 로고
    • Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis
    • Monje M, Dietrich J. Cognitive side effects of cancer therapy demonstrate a functional role for adult neurogenesis. Behav Brain Res 2011; 227:376-379.
    • (2011) Behav Brain Res , vol.227 , pp. 376-379
    • Monje, M.1    Dietrich, J.2
  • 36
    • 0017701702 scopus 로고
    • Neurogenesis in the adult rat: Electron microscopic analysis of light radioautographs
    • Kaplan MS, Hinds JW. Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs. Science 1977; 197:1092-1094.
    • (1977) Science , vol.197 , pp. 1092-1094
    • Kaplan, M.S.1    Hinds, J.W.2
  • 37
    • 0021125307 scopus 로고
    • Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus
    • Kaplan MS, Bell DH. Mitotic neuroblasts in the 9-day-old and 11-month-old rodent hippocampus. J Neurosci 1984; 4:1429-1441.
    • (1984) J Neurosci , vol.4 , pp. 1429-1441
    • Kaplan, M.S.1    Bell, D.H.2
  • 39
    • 33645098296 scopus 로고    scopus 로고
    • Is there a link between adult neurogenesis and learning?
    • Leuner B, Gould E, Shors TJ. Is there a link between adult neurogenesis and learning? Hippocampus 2006; 16:216-224.
    • (2006) Hippocampus , vol.16 , pp. 216-224
    • Leuner, B.1    Gould, E.2    Shors, T.J.3
  • 40
    • 67650450542 scopus 로고    scopus 로고
    • A functional role for adult hippocampal neurogenesis in spatial pattern separation
    • Clelland CD, Choi M, Romberg C, et al. A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 2009; 325:210-213.
    • (2009) Science , vol.325 , pp. 210-213
    • Clelland, C.D.1    Choi, M.2    Romberg, C.3
  • 41
    • 0033363319 scopus 로고    scopus 로고
    • Learning enhances adult neurogenesis in the hippocampal formation
    • Gould E, Beylin A, Tanapat P, et al. Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 1999; 2:260-265.
    • (1999) Nat Neurosci , vol.2 , pp. 260-265
    • Gould, E.1    Beylin, A.2    Tanapat, P.3
  • 42
    • 4444381084 scopus 로고    scopus 로고
    • Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory
    • Leuner B, Mendolia-Loffredo S, Kozorovitskiy Y, et al. Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory. J Neurosci 2004; 24:7477-7481.
    • (2004) J Neurosci , vol.24 , pp. 7477-7481
    • Leuner, B.1    Mendolia-Loffredo, S.2    Kozorovitskiy, Y.3
  • 43
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • Kempermann G, Kuhn HG, Gage FH. More hippocampal neurons in adult mice living in an enriched environment. Nature 1997; 386:493-495.
    • (1997) Nature , vol.386 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 44
  • 45
    • 44949098333 scopus 로고    scopus 로고
    • Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment
    • Angevaren M, Aufdemkampe G, Verhaar HJ, et al. Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. Cochrane Database Syst Rev 2008; CD005381.
    • (2008) Cochrane Database Syst Rev
    • Angevaren, M.1    Aufdemkampe, G.2    Verhaar, H.J.3
  • 46
    • 0035868717 scopus 로고    scopus 로고
    • Neurogenesis in the adult is involved in the formation of trace memories
    • Shors TJ, Miesegaes G, Beylin A, et al. Neurogenesis in the adult is involved in the formation of trace memories. Nature 2001; 410:372-376.
    • (2001) Nature , vol.410 , pp. 372-376
    • Shors, T.J.1    Miesegaes, G.2    Beylin, A.3
  • 47
    • 0142250835 scopus 로고    scopus 로고
    • NG2-expressing glial progenitor cells: An abundant and widespread population of cycling cells in the adult rat CNS
    • Dawson MR, Polito A, Levine JM, Reynolds R. NG2-expressing glial progenitor cells: an abundant and widespread population of cycling cells in the adult rat CNS. Mol Cell Neurosci 2003; 24:476-488.
    • (2003) Mol Cell Neurosci , vol.24 , pp. 476-488
    • Dawson, M.R.1    Polito, A.2    Levine, J.M.3    Reynolds, R.4
  • 48
    • 0034281366 scopus 로고    scopus 로고
    • NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions
    • Chang A, Nishiyama A, Peterson J, et al. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J Neurosci 2000; 20:6404-6412.
    • (2000) J Neurosci , vol.20 , pp. 6404-6412
    • Chang, A.1    Nishiyama, A.2    Peterson, J.3
  • 49
    • 75949085273 scopus 로고    scopus 로고
    • NG2 +Olig2+ cells are the major cyclerelated cell population of the adult human normal brain
    • Geha S, Pallud J, Junier MP, et al. NG2 +Olig2+ cells are the major cyclerelated cell population of the adult human normal brain. Brain Pathol 2010; 20:399-411.
    • (2010) Brain Pathol , vol.20 , pp. 399-411
    • Geha, S.1    Pallud, J.2    Junier, M.P.3
  • 50
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • Monje ML, Mizumatsu S, Fike JR, Palmer TD. Irradiation induces neural precursor-cell dysfunction. Nat Med 2002; 8:955-962.
    • (2002) Nat Med , vol.8 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 51
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje ML, Toda H, Palmer TD. Inflammatory blockade restores adult hippocampal neurogenesis. Science 2003; 302:1760-1765.
    • (2003) Science , vol.302 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 52
    • 70349560028 scopus 로고    scopus 로고
    • The PPARa agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation
    • Ramanan S, Kooski M, Zhao W. The PPARa agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation. Int J Radiat Oncol Biol Phys 2009; 75:870-877.
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , pp. 870-877
    • Ramanan, S.1    Kooski, M.2    Zhao, W.3
  • 53
    • 37349127393 scopus 로고    scopus 로고
    • Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies
    • Monje ML, Vogel H, Masek M, et al. Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies. Ann Neurol 2007; 62:515-520.
    • (2007) Ann Neurol , vol.62 , pp. 515-520
    • Monje, M.L.1    Vogel, H.2    Masek, M.3
  • 54
    • 77956813407 scopus 로고    scopus 로고
    • Mitochondrial protection attenuates inflammation-induced impairment of neurogenesis in vitro and in vivo
    • Voloboueva LA, Lee SW, Emery JF, et al. Mitochondrial protection attenuates inflammation-induced impairment of neurogenesis in vitro and in vivo. J Neurosci 2010; 30:12242-12251.
    • (2010) J Neurosci , vol.30 , pp. 12242-12251
    • Voloboueva, L.A.1    Lee, S.W.2    Emery, J.F.3
  • 55
    • 55749088804 scopus 로고    scopus 로고
    • Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain
    • Naylor AS, Bull C, Nilsson MK, et al. Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain. Proc Natl Acad Sci USA 2008; 105:14632-14637.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14632-14637
    • Naylor, A.S.1    Bull, C.2    Nilsson, M.K.3
  • 56
    • 78549282823 scopus 로고    scopus 로고
    • Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation
    • Wong-Goodrich SJ, Pfau ML, Flores CT, et al. Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation. Cancer Res 2010; 70:9329-9338.
    • (2010) Cancer Res , vol.70 , pp. 9329-9338
    • Wong-Goodrich, S.J.1    Pfau, M.L.2    Flores, C.T.3
  • 57
    • 77952551092 scopus 로고    scopus 로고
    • Cyclophosphamide impairs hippocampusdependent learning and memory in adult mice: Possible involvement of hippocampal neurogenesis in chemotherapy-induced memory deficits
    • Yang M, Kim JS, Song MS, et al. Cyclophosphamide impairs hippocampusdependent learning and memory in adult mice: Possible involvement of hippocampal neurogenesis in chemotherapy-induced memory deficits. Neurobiol Learn Mem 2010; 93:487-494.
    • (2010) Neurobiol Learn Mem , vol.93 , pp. 487-494
    • Yang, M.1    Kim, J.S.2    Song, M.S.3
  • 58
    • 67349085108 scopus 로고    scopus 로고
    • Methotrexate decreases hippocampal cell proliferation and induces memory deficits in rats
    • Seigers R, Schagen SB, Coppens CM, et al. Methotrexate decreases hippocampal cell proliferation and induces memory deficits in rats. Behav Brain Res 2009; 201:279-284.
    • (2009) Behav Brain Res , vol.201 , pp. 279-284
    • Seigers, R.1    Schagen, S.B.2    Coppens, C.M.3
  • 59
    • 84859396336 scopus 로고    scopus 로고
    • Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy
    • Christie LA, Acharya MM, Parihar VK, et al. Impaired cognitive function and hippocampal neurogenesis following cancer chemotherapy. Clin Cancer Res 2012; 18:1954-1965.
    • (2012) Clin Cancer Res , vol.18 , pp. 1954-1965
    • Christie, L.A.1    Acharya, M.M.2    Parihar, V.K.3
  • 60
    • 54049083455 scopus 로고    scopus 로고
    • Voxel-based morphometry and diffusion-tensor MR imaging of the brain in long-term survivors of childhood leukemia
    • Porto L, Preibisch C, Hattingen E, et al. Voxel-based morphometry and diffusion-tensor MR imaging of the brain in long-term survivors of childhood leukemia. Eur Radiol 2008; 18:2691-2700.
    • (2008) Eur Radiol , vol.18 , pp. 2691-2700
    • Porto, L.1    Preibisch, C.2    Hattingen, E.3
  • 61
    • 67349281455 scopus 로고    scopus 로고
    • White matter fractional anisotropy correlates with speed of processing and motor speed in young childhood cancer survivors
    • Aukema EJ, Caan MW, Oudhuis N, et al. White matter fractional anisotropy correlates with speed of processing and motor speed in young childhood cancer survivors. Int J Radiat Oncol Biol Phys 2009; 74:837-843.
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 837-843
    • Aukema, E.J.1    Caan, M.W.2    Oudhuis, N.3
  • 62
    • 79951471900 scopus 로고    scopus 로고
    • Chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning in breast cancer patients
    • Deprez S, Amant F, Yigit R, et al. Chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning in breast cancer patients. Hum Brain Mapp 2011; 32:480-493.
    • (2011) Hum Brain Mapp , vol.32 , pp. 480-493
    • Deprez, S.1    Amant, F.2    Yigit, R.3
  • 63
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and functional implications of adult neurogenesis
    • Zhao C, Deng W, Gage FH. Mechanisms and functional implications of adult neurogenesis. Cell 2008; 132:645-660.
    • (2008) Cell , vol.132 , pp. 645-660
    • Zhao, C.1    Deng, W.2    Gage, F.H.3
  • 64
    • 0029860591 scopus 로고    scopus 로고
    • Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
    • Weiss S, Dunne C, Hewson J, et al. Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J Neurosci 1996; 16:7599-7609.
    • (1996) J Neurosci , vol.16 , pp. 7599-7609
    • Weiss, S.1    Dunne, C.2    Hewson, J.3
  • 65
    • 0029003681 scopus 로고
    • A comparison of the effects of methotrexate and misonidazole on the germinal cells of the subependymal plate of the rat
    • Morris GM, Hopewell JW, Morris AD. A comparison of the effects of methotrexate and misonidazole on the germinal cells of the subependymal plate of the rat. Br J Radiol 1995; 68:406-412.
    • (1995) Br J Radiol , vol.68 , pp. 406-412
    • Morris, G.M.1    Hopewell, J.W.2    Morris, A.D.3
  • 66
    • 4444366001 scopus 로고    scopus 로고
    • Anticancer agents are potent neurotoxins in vitro and in vivo
    • Rzeski W, Pruskil S, Macke A, et al. Anticancer agents are potent neurotoxins in vitro and in vivo. Ann Neurol 2004; 56:351-360.
    • (2004) Ann Neurol , vol.56 , pp. 351-360
    • Rzeski, W.1    Pruskil, S.2    MacKe, A.3
  • 67
    • 33846991965 scopus 로고    scopus 로고
    • CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo
    • Dietrich J, Han R, Yang Y, et al. CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo. J Biol 2006; 5:22.
    • (2006) J Biol , vol.5 , pp. 22
    • Dietrich, J.1    Han, R.2    Yang, Y.3
  • 68
    • 42549123787 scopus 로고    scopus 로고
    • Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system
    • Han R, Yang YM, Dietrich J, et al. Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system. J Biol 2008; 7:12.
    • (2008) J Biol , vol.7 , pp. 12
    • Han, R.1    Yang, Y.M.2    Dietrich, J.3
  • 69
    • 76049118429 scopus 로고    scopus 로고
    • Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation
    • Schoenfeld R, Wong A, Silva J, et al. Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation. Mitochondrion 2010; 10:143-150.
    • (2010) Mitochondrion , vol.10 , pp. 143-150
    • Schoenfeld, R.1    Wong, A.2    Silva, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.