A new insight into the dissociating effect of strontium on bone resorption and formation

Acta Biomaterialia

Volumn 7, Issue 6, 2011, Pages 2593-2603

  Braux, Julien ^a,b   Velard, Frédéric ^a   Guillaume, Christine ^a   Bouthors, Sylvie ^a   Jallot, Edouard ^c   Nedelec, Jean Marie ^c   Laurent Maquin, Dominique ^a,b   Laquerrière, Patrice ^a,d,e  

^a UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^b REIMS UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ CLERMONT AUVERGNE   (France)

^d INSTITUT DE RECHERCHES SUBATOMIQUES   (France)

^e UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Bone; Extracellular matrix; Hydroxyapatite; Matrix metalloproteinase; Strontium

Indexed keywords

BIOSYNTHESIS; BONE; CALCIUM PHOSPHATE; CHLORINE COMPOUNDS; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; SOL-GEL PROCESS; SOL-GELS; STRONTIUM COMPOUNDS;

BIPHASIC CALCIUM PHOSPHATES; BONE CELLS; BONE FORMATION; BONE RESORPTION; EXTRACELLULAR MATRICES; EXTRACELLULAR MATRIX SYNTHESIS; MATRIX; MATRIX METALLOPROTEINASE; METALLOPROTEINASES; OSTEOSYNTHESIS;

HYDROXYAPATITE;

CALCIUM PHOSPHATE; COLLAGEN TYPE 1; GELATINASE A; INTERSTITIAL COLLAGENASE; MESSENGER RNA; SERINE PROTEINASE INHIBITOR; SERPINH1 PROTEIN; STRONTIUM; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ARTICLE; BONE CELL; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN CELL; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; POWDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SUBSTITUTION REACTION;

EID: 79955628637     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.02.013     Document Type: Article

References (47)

1. MacArthur BD, Oreffo RO. Bridging the gap. Nature 2005;433(7021):19. (Pubitemid 40101127)
2. Webster TJ. Nanophase ceramics: the future of orthopaedic and dental implant material. In: Ying JY, editor. Nanostructured materials. Academic Press: New York; 2001. p. 125-66.
3. LeGeros RZ. Properties of osteoconductive biomaterials: calcium phosphates. Clin Orthop Relat Res 2002;395:81-98. (Pubitemid 34136659)
4. Sun L, Berndt CC, Gross KA, Kucuk A. Material fundamentals and clinical performance of plasma-sprayed hydroxyapatite coatings: a review. J Biomed Mater Res Appl Biomater 2001;58:570-92. (Pubitemid 32899914)
5. Yang Y, Kim KH, Ong JL. A review on calcium phosphate coatings produced using a sputtering process-an alternative to plasma spraying. Biomaterials 2005;26:327-37. (Pubitemid 38950717)
6. Bloebaum RD, Zou L, Bachus KN, Shea KG, Hofmann AA, Dunn HK. Analysis of particles in acetabular components from patients with osteolysis. Clin Orthop Related Res 1997;338:109-18. (Pubitemid 27203455)
7. Arinzeh TL, Tran T, Mcalary J, Daculsi G. A comparative study of biphasic calcium phosphate ceramics for human mesenchymal stem-cell-induced bone formation. Biomaterials 2005;26(17):3631-8. (Pubitemid 40038157)
8. Marie PJ, Felsenberg D, Brandi ML. How strontium ranelate, via opposite effects on bone resorption and formation, prevents osteoporosis. Osteoporos Int. 2010 [Epub ahead of print].
9. Marie PJ. Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation. Curr Opin Rheumatol 2006;18(suppl 1):S11-5.
10. Baron R, Tsouderos Y. In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation. Eur J Pharmacol 2002;450(1):11-7.
11. Bonnelye E, Chabadel A, Saltel F, Jurdic P. Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro. Bone 2008;42(1):129-38. (Pubitemid 350297175)
12. Hurtel-Lemaire AS, Mentaverri R, Caudrillier A, Cournarie F, Wattel A, Kamel S, et al. The calcium-sensing receptor is involved in strontium ranelate-induced osteoclast apoptosis. New insights into the associated signaling pathways. J Biol Chem 2009;284(1):575-84.
13. Chang W, Tu C, Chen TH, Komuves L, Oda Y, Pratt SA, et al. Expression and signal transduction of calcium-sensing receptors in cartilage and bone. Endocrinology 1999;140(12):5883-93. (Pubitemid 30645377)
14. Caverzasio J. Strontium ranelate promotes osteoblastic cell replication through at least two different mechanisms. Bone 2008;42(6):1131-6.
15. Canalis E, Hott M, Deloffre P, Tsouderos Y, Marie PJ. The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro. Bone 1996;18(6):517-23. (Pubitemid 26257871)
16. Chattopadhyay N, Quinn SJ, Kifor O, Ye C, Brown EM. The calcium-sensing receptor (CaR) is involved in strontium ranelate-induced osteoblast proliferation. Biochem Pharmacol 1997;74(3):438-47.
17. Atkins GJ, Welldon KJ, Halbout P, Findlay DM. Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response. Osteoporos Int 2009;20(4):653-64.
18. Wu C, Ramaswamy Y, Kwik D, Zreiqat H. The effect of strontium incorporation into CaSiO3 ceramics on their physical and biological properties. Biomaterials 2007;28(21):3171-81. (Pubitemid 46661856)
19. Gentleman E, Fredholm YC, Jell G, Lotfibakhshaiesh N, O'Donnell MD, Hill RG, et al. The effects of strontium-substituted bioactive glasses on osteoblasts and osteoclasts in vitro. Biomaterials 2010;31(14):3949-56.
20. Peng S, Zhou G, Luk KD, Cheung KM, Li Z, Lam WM, et al. Strontium promotes osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway. Cell Physiol Biochem 2009;23(1-3):165-74.
21. Zreiqat H, Ramaswamy Y, Wu C, Paschalidis A, Lu Z, James B, et al. The incorporation of strontium and zinc into a calcium-silicon ceramic for bone tissue engineering. Biomaterials 2010;31(12):3175-84.
22. Li Z, Lu WW, Chiu PK, Lam RW, Xu B, Cheung KM, et al. Strontium-calcium coadministration stimulates bone matrix osteogenic factor expression and new bone formation in a large animal model. J Orthop Res 2009;27(6):758-62.
23. Peng S, Liu XS, Wang T, Li Z, Zhou G, Luk KD, et al. In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells. J Orthop Res 2010;28(9):1208-14.
24. Renaudin G, Laquerriere P, Filinchuk Y, Jallot E, Nedelec JM. Structural characterization of sol-gel derived Sr-substituted calcium phosphates with anti-osteoporotic and anti-inflammatory properties. J Mater Chem 2008;18:3593-600.
25. Shanbhag AS, Jacobs JJ, Black J, Galante JO, Glant TT. Macrophage/particle interactions: effect of size, composition and surface area. J Biomed Mater Res 1994;28(1):81-90. (Pubitemid 24006480)
26. Alliot-Licht B, Gregoire M, Orly I, Menanteau J. Cellular activity of osteoblasts in the presence of hydroxyapatite: an in vitro experiment. Biomaterials 1991;12(8):752-6.
27. Laquerriere P, Grandjean-Laquerriere A, Killian L, Beorchia A, Guenounou M, Jallot E, et al. Influence of hydroxyapatite particle characteristics on the [K]/[Na] ratio: a human monocytes in vitro study. Colloid Surf B 2004;33:49-55.
28. Grandjean-Laquerriere A, Laquerriere P, Guenounou M, Laurent-Maquin D, Phillips TM. Importance of the surface area ratio on cytokines production by human monocytes in vitro induced by various hydroxyapatite particles. Biomaterials 2005;26(15):2361-9. (Pubitemid 39600689)
29. Schmidt C, Kaspar D, Sarkar MR, Claes LE, Ignatius AA. A scanning electron microscopy study of human osteoblast morphology on five orthopedic metals. J Biomed Mater Res 2002;63(3):252-61. (Pubitemid 34521327)
30. Lian JB, Stein GS. Development of the osteoblasts phenotype: molecular mechanisms mediating osteoblasts growth and differentiation. Iowa Orthop J 1995;15:118-40.
31. Dahl SG, Allain P, Marie PJ, Mauras Y, Boivin G, Ammann P, et al. Incorporation and distribution of strontium in bone. Bone 2001;28(4):446-53. (Pubitemid 32385418)
32. O'Donnell MD, Candarlioglu PL, Miller CA, Gentleman E, Stevens MM. Materials characterisation and cytotoxic assessment of strontium-substituted bioactive glasses for bone regeneration. J Mater Chem 2010;20:8934-41.
33. Alkhraisat MH, Moseke K, Blanco L, Barralet JE, Lopez-Carbacos E, Gbureck U. Strontium modified biocements with zero order release kinetics. Biomaterials 2008;29(35):4691-7.
34. Marie PJ. Strontium ranelate: a physiological approach for optimizing bone formation and resorption. Bone 2006;38(2 Suppl. 1):10-14.
35. Marie PJ. Strontium ranelate: a novel mode of action optimizing bone formation and resorption. Osteoporos Int 2005;16(Suppl 1):S7-S10. (Pubitemid 40768190)
36. Capuccini C, Torricelli P, Sima F, Boanini E, Ristoscu C, Bracci B, et al. Strontium-substituted hydroxyapatite coatings synthesized by pulsed-laser deposition: in vitro osteoblast and osteoclast response. Acta Biomater 2008;4(6):1885-93.
37. Rocnik EF, van der Veer E, Cao H, Hegele RA, Pickering JG. Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells. J Biol Chem 2002;277(41):38571-8. (Pubitemid 35154717)
38. Fuller K, Chambers TJ. Localisation of mRNA for collagenase in osteocytic, bone surface and chondrocytic cells but not osteoclasts. J Cell Sci 1995;108:2221-30.
39. Delaisse JM, Eeckhout Y, Sear C, Galloway A, McCullagh K, Vaes G. A new synthetic inhibitor of mammalian tissue collagenase inhibits bone resorption in culture. Biochem Biophys Res Commun 1985;133:483-90. (Pubitemid 16103877)
40. Partridge NC, Jeffrey JJ, Ehlich LS, Teitelbaum SL, Fliszar C, Welgus HG, et al. Hormonal regulation of the production of collagenase and a collagenase inhibitor activity by rat osteogenic sarcoma cells. Endocrinology 1987;120:1956-62. (Pubitemid 17069229)
41. Quinn CO, Scott DK, Brinckerhoff CE, Matrisian LM, Jeffrey JJ, Partridge NC. Rat collagenase cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J Biol Chem 1990;265:22342-7. (Pubitemid 120014307)
42. Geoffroy V, Marty-Morieux C, Le Goupil N, Clement-Lacroix P, Terraz C, Frain M, et al. In vivo inhibition of osteoblastic metalloproteinases leads to increased trabecular bone mass. J Bone Miner Res 2004;19(5):811-22.
43. Everts V, Delaisse JM, Korper W, Niehof A, Vaes G, Beertsen W. Degradation of collagen in the bone-resorbing compartment underlying the osteoclast involves both cystein-proteinases and matrix metalloproteinases. J Cell Physiol 1992;150:221-31.
44. Chambers TJ, Darby JA, Fuller K. Mammalian collagenase predisposes bone surfaces to osteoclastic resorption. Cell Tissue Res 1985;241:671-5.
45. Chambers TJ, Fuller K. Bone cells predispose bone surfaces to resorption by exposure of mineral to osteoclastic contact. J Cell Sci 1985;76:155-65.
46. Henrotin Y, Labasse A, Zheng SX, Galais P, Tsouderos Y, Crielaard JM, et al. Strontium ranelate increases cartilage matrix formation. J Bone Miner Res 2001;16(2):299-308. (Pubitemid 32105411)
47. Zhang Q, Liu HR, Ying HJ, Dai DZ, Tang XY, Dai Y. Strontium fructose 1,6- diphosphate alleviates early diabetic testopathy by suppressing abnormal testicular matrix metalloproteinase system in streptozocin-treated rats. J Pharm Pharmacol 2009;61(2):229-36.