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Volumn 64, Issue 11, 2012, Pages 3649-3659

Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: Implications for insufficiency fracture risk

Author keywords

[No Author keywords available]

Indexed keywords

PREDNISOLONE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84868129753     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.34639     Document Type: Article
Times cited : (39)

References (51)
  • 1
    • 33745054420 scopus 로고    scopus 로고
    • High prevalence of asymptomatic vertebral fractures in post-menopausal women receiving chronic glucocorticoid therapy: A cross-sectional outpatient study
    • Angeli A, Guglielmi G, Dovio A, Capelli G, de Feo D, Giannini S, et al. High prevalence of asymptomatic vertebral fractures in post-menopausal women receiving chronic glucocorticoid therapy: a cross-sectional outpatient study. Bone 2006; 39: 253-9.
    • (2006) Bone , vol.39 , pp. 253-259
    • Angeli, A.1    Guglielmi, G.2    Dovio, A.3    Capelli, G.4    De Feo, D.5    Giannini, S.6
  • 3
    • 41849085159 scopus 로고    scopus 로고
    • Characteristics of fracture and related factors in patients with rheumatoid arthritis
    • Nampei A, Hashimoto J, Koyanagi J, Ono T, Hashimoto H, Tsumaki N, et al. Characteristics of fracture and related factors in patients with rheumatoid arthritis. Mod Rheumatol 2008; 18: 170-6.
    • (2008) Mod Rheumatol , vol.18 , pp. 170-176
    • Nampei, A.1    Hashimoto, J.2    Koyanagi, J.3    Ono, T.4    Hashimoto, H.5    Tsumaki, N.6
  • 4
    • 0042838281 scopus 로고    scopus 로고
    • Inflammatory mediators as essential elements in bone remodeling
    • Goldring SR,. Inflammatory mediators as essential elements in bone remodeling. Calcif Tissue Int 2003; 73: 97-100.
    • (2003) Calcif Tissue Int , vol.73 , pp. 97-100
    • Goldring, S.R.1
  • 5
    • 53149122891 scopus 로고    scopus 로고
    • Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins
    • Guo R, Yamashita M, Zhang Q, Zhou Q, Chen D, Reynolds DG, et al. Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins. J Biol Chem 2008; 283: 23084-92.
    • (2008) J Biol Chem , vol.283 , pp. 23084-23092
    • Guo, R.1    Yamashita, M.2    Zhang, Q.3    Zhou, Q.4    Chen, D.5    Reynolds, D.G.6
  • 6
    • 33645226966 scopus 로고    scopus 로고
    • Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts
    • Kaneki H, Guo R, Chen D, Yao Z, Schwarz EM, Zhang YE, et al. Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. J Biol Chem 2006; 281: 4326-33.
    • (2006) J Biol Chem , vol.281 , pp. 4326-4333
    • Kaneki, H.1    Guo, R.2    Chen, D.3    Yao, Z.4    Schwarz, E.M.5    Zhang, Y.E.6
  • 7
    • 0242409906 scopus 로고    scopus 로고
    • Tumor necrosis factor-α: Molecular and cellular mechanisms in skeletal pathology
    • Nanes MS,. Tumor necrosis factor-α: molecular and cellular mechanisms in skeletal pathology. Gene 2003; 321: 1-15.
    • (2003) Gene , vol.321 , pp. 1-15
    • Nanes, M.S.1
  • 8
    • 80053281947 scopus 로고    scopus 로고
    • Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1
    • Zhao L, Huang J, Zhang H, Wang Y, Matesic LE, Takahata M, et al. Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1. Stem Cells 2011; 29: 1601-10.
    • (2011) Stem Cells , vol.29 , pp. 1601-1610
    • Zhao, L.1    Huang, J.2    Zhang, H.3    Wang, Y.4    Matesic, L.E.5    Takahata, M.6
  • 10
    • 33645299091 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis and its treatment
    • Pennisi P, Trombetti A, Rizzoli R,. Glucocorticoid-induced osteoporosis and its treatment. Clin Orthop Relat Res 2006; 443: 39-47.
    • (2006) Clin Orthop Relat Res , vol.443 , pp. 39-47
    • Pennisi, P.1    Trombetti, A.2    Rizzoli, R.3
  • 11
    • 42549164669 scopus 로고    scopus 로고
    • Rheumatoid arthritis and other inflammatory joint pathologies
    • Seibel M.J. Robins S.P. Bilezikian J.P. editors. Burlington (MA): Academic Press;. p
    • Goldring SR, Goldring MB,. Rheumatoid arthritis and other inflammatory joint pathologies. In:, Seibel MJ, Robins SP, Bilezikian JP, editors. Dynamics of bone and cartilage metabolism. Burlington (MA): Academic Press; 2006. p. 843-69.
    • (2006) Dynamics of Bone and Cartilage Metabolism , pp. 843-869
    • Goldring, S.R.1    Goldring, M.B.2
  • 12
    • 0042232230 scopus 로고    scopus 로고
    • The TNF-α transgenic mouse model of inflammatory arthritis
    • Li P, Schwarz EM,. The TNF-α transgenic mouse model of inflammatory arthritis. Springer Semin Immunopathol 2003; 25: 19-33.
    • (2003) Springer Semin Immunopathol , vol.25 , pp. 19-33
    • Li, P.1    Schwarz, E.M.2
  • 13
    • 0026039673 scopus 로고
    • Transgenic mice expressing human tumour necrosis factor: A predictive genetic model of arthritis
    • Keffer J, Probert L, Cazlaris H, Georgopoulos S, Kaslaris E, Kioussis D, et al. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J 1991; 10: 4025-31.
    • (1991) EMBO J , vol.10 , pp. 4025-4031
    • Keffer, J.1    Probert, L.2    Cazlaris, H.3    Georgopoulos, S.4    Kaslaris, E.5    Kioussis, D.6
  • 14
  • 15
    • 33644549962 scopus 로고    scopus 로고
    • Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice
    • Lane NE, Yao W, Balooch M, Nalla RK, Balooch G, Habelitz S, et al. Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice. J Bone Miner Res 2006; 21: 466-76.
    • (2006) J Bone Miner Res , vol.21 , pp. 466-476
    • Lane, N.E.1    Yao, W.2    Balooch, M.3    Nalla, R.K.4    Balooch, G.5    Habelitz, S.6
  • 16
    • 77649205349 scopus 로고    scopus 로고
    • Determination of ideal offset for spatially offset Raman spectroscopy
    • Maher JR, Berger AJ,. Determination of ideal offset for spatially offset Raman spectroscopy. Appl Spectrosc 2010; 64: 61-5.
    • (2010) Appl Spectrosc , vol.64 , pp. 61-65
    • Maher, J.R.1    Berger, A.J.2
  • 17
    • 80455137144 scopus 로고    scopus 로고
    • Raman spectroscopy detects deterioration in biomechanical properties of bone in a glucocorticoid-treated mouse model of rheumatoid arthritis
    • Maher JR, Takahata M, Awad HA, Berger AJ,. Raman spectroscopy detects deterioration in biomechanical properties of bone in a glucocorticoid-treated mouse model of rheumatoid arthritis. J Biomed Opt 2011; 16: 087012.
    • (2011) J Biomed Opt , vol.16 , pp. 087012
    • Maher, J.R.1    Takahata, M.2    Awad, H.A.3    Berger, A.J.4
  • 19
    • 34948884021 scopus 로고    scopus 로고
    • Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts
    • Reynolds DG, Hock C, Shaikh S, Jacobson J, Zhang X, Rubery PT, et al. Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts. J Biomech 2007; 40: 3178-86.
    • (2007) J Biomech , vol.40 , pp. 3178-3186
    • Reynolds, D.G.1    Hock, C.2    Shaikh, S.3    Jacobson, J.4    Zhang, X.5    Rubery, P.T.6
  • 20
    • 0004207547 scopus 로고    scopus 로고
    • Cowin S.C. editor. 2nd ed. Boca Raton (FL): CRC Press
    • Cowin SC, editor. Bone mechanics handbook. 2nd ed. Boca Raton (FL): CRC Press; 2001.
    • (2001) Bone Mechanics Handbook
  • 21
    • 0023488581 scopus 로고
    • Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the ASBMR Histomorphometry Nomenclature Committee
    • Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, et al. Bone histomorphometry: standardization of nomenclature, symbols, and units: report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 1987; 2: 595-610.
    • (1987) J Bone Miner Res , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5    Meunier, P.J.6
  • 22
    • 1542346348 scopus 로고    scopus 로고
    • Age-related changes in physicochemical properties of mineral crystals are related to impaired mechanical function of cortical bone
    • Akkus O, Adar F, Schaffler MB,. Age-related changes in physicochemical properties of mineral crystals are related to impaired mechanical function of cortical bone. Bone 2004; 34: 443-53.
    • (2004) Bone , vol.34 , pp. 443-453
    • Akkus, O.1    Adar, F.2    Schaffler, M.B.3
  • 23
    • 33750356231 scopus 로고    scopus 로고
    • Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis
    • van Staa TP, Geusens P, Bijlsma JW, Leufkens HG, Cooper C,. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 2006; 54: 3104-12.
    • (2006) Arthritis Rheum , vol.54 , pp. 3104-3112
    • Van Staa, T.P.1    Geusens, P.2    Bijlsma, J.W.3    Leufkens, H.G.4    Cooper, C.5
  • 24
    • 0033233166 scopus 로고    scopus 로고
    • Growing C57BL/6 mice increase whole bone mechanical properties by increasing geometric and material properties
    • Brodt MD, Ellis CB, Silva MJ,. Growing C57BL/6 mice increase whole bone mechanical properties by increasing geometric and material properties. J Bone Mineral Res 1999; 14: 2159-66.
    • (1999) J Bone Mineral Res , vol.14 , pp. 2159-2166
    • Brodt, M.D.1    Ellis, C.B.2    Silva, M.J.3
  • 25
    • 29644442623 scopus 로고    scopus 로고
    • Decreased collagen organization and content are associated with reduced strength of demineralized and intact bone in the SAMP6 mouse
    • Silva MJ, Brodt MD, Wopenka B, Thomopoulos S, Williams D, Wassen MH, et al. Decreased collagen organization and content are associated with reduced strength of demineralized and intact bone in the SAMP6 mouse. J Bone Miner Res 2006; 21: 78-88.
    • (2006) J Bone Miner Res , vol.21 , pp. 78-88
    • Silva, M.J.1    Brodt, M.D.2    Wopenka, B.3    Thomopoulos, S.4    Williams, D.5    Wassen, M.H.6
  • 26
    • 0142139185 scopus 로고    scopus 로고
    • Ash content modulation of torsionally derived effective material properties in cortical mouse bone
    • Battaglia TC, Tsou AC, Taylor EA, Mikic B,. Ash content modulation of torsionally derived effective material properties in cortical mouse bone. J Biomech Eng 2003; 125: 615-9.
    • (2003) J Biomech Eng , vol.125 , pp. 615-619
    • Battaglia, T.C.1    Tsou, A.C.2    Taylor, E.A.3    Mikic, B.4
  • 27
    • 0016752354 scopus 로고
    • Contribution of collagen and mineral to the elastic-plastic properties of bone
    • Burstein AH, Zika JM, Heiple KG, Klein L,. Contribution of collagen and mineral to the elastic-plastic properties of bone. J Bone Joint Surg Am 1975; 57: 956-61.
    • (1975) J Bone Joint Surg Am , vol.57 , pp. 956-961
    • Burstein, A.H.1    Zika, J.M.2    Heiple, K.G.3    Klein, L.4
  • 28
    • 0023873049 scopus 로고
    • The effect of porosity and mineral content on the Young's modulus of elasticity of compact bone
    • Currey JD,. The effect of porosity and mineral content on the Young's modulus of elasticity of compact bone. J Biomech 1988; 21: 131-9.
    • (1988) J Biomech , vol.21 , pp. 131-139
    • Currey, J.D.1
  • 30
    • 0036309121 scopus 로고    scopus 로고
    • The contribution of the organic matrix to bone's material properties
    • Burr DB,. The contribution of the organic matrix to bone's material properties. Bone 2002; 31: 8-11.
    • (2002) Bone , vol.31 , pp. 8-11
    • Burr, D.B.1
  • 31
    • 0016170096 scopus 로고
    • The mechanical properties of cortical bone
    • [review]
    • Reilly DT, Burstein AH,. The mechanical properties of cortical bone [review]. J Bone Joint Surg Am 1974; 56: 1001-22.
    • (1974) J Bone Joint Surg Am , vol.56 , pp. 1001-1022
    • Reilly, D.T.1    Burstein, A.H.2
  • 32
    • 0024711963 scopus 로고
    • Yield behavior of bovine cancellous bone
    • Turner CH,. Yield behavior of bovine cancellous bone. J Biomech Eng 1989; 111: 256-60.
    • (1989) J Biomech Eng , vol.111 , pp. 256-260
    • Turner, C.H.1
  • 33
    • 78651088561 scopus 로고    scopus 로고
    • Raman and mechanical properties correlate at whole bone- and tissue-levels in a genetic mouse model
    • Bi X, Patil CA, Lynch CC, Pharr GM, Mahadevan-Jansen A, Nyman JS,. Raman and mechanical properties correlate at whole bone- and tissue-levels in a genetic mouse model. J Biomech 2011; 44: 297-303.
    • (2011) J Biomech , vol.44 , pp. 297-303
    • Bi, X.1    Patil, C.A.2    Lynch, C.C.3    Pharr, G.M.4    Mahadevan-Jansen, A.5    Nyman, J.S.6
  • 36
    • 34247094322 scopus 로고    scopus 로고
    • Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation
    • Valcourt U, Merle B, Gineyts E, Viguet-Carrin S, Delmas PD, Garnero P,. Non-enzymatic glycation of bone collagen modifies osteoclastic activity and differentiation. J Biol Chem 2007; 282: 5691-703.
    • (2007) J Biol Chem , vol.282 , pp. 5691-5703
    • Valcourt, U.1    Merle, B.2    Gineyts, E.3    Viguet-Carrin, S.4    Delmas, P.D.5    Garnero, P.6
  • 37
    • 33749518488 scopus 로고    scopus 로고
    • Contribution of the advanced glycation end product pentosidine and of maturation of type i collagen to compressive biomechanical properties of human lumbar vertebrae
    • Viguet-Carrin S, Roux JP, Arlot ME, Merabet Z, Leeming DJ, Byrjalsen I, et al. Contribution of the advanced glycation end product pentosidine and of maturation of type I collagen to compressive biomechanical properties of human lumbar vertebrae. Bone 2006; 39: 1073-9.
    • (2006) Bone , vol.39 , pp. 1073-1079
    • Viguet-Carrin, S.1    Roux, J.P.2    Arlot, M.E.3    Merabet, Z.4    Leeming, D.J.5    Byrjalsen, I.6
  • 40
    • 79957526871 scopus 로고    scopus 로고
    • Advances in glucocorticoid-induced osteoporosis
    • Den Uyl D, Bultink IE, Lems WF,. Advances in glucocorticoid-induced osteoporosis. Curr Rheumatol Rep 2011; 13: 233-40.
    • (2011) Curr Rheumatol Rep , vol.13 , pp. 233-240
    • Den Uyl, D.1    Bultink, I.E.2    Lems, W.F.3
  • 41
    • 45349088375 scopus 로고    scopus 로고
    • Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: A longitudinal study of gene expression in bone tissue from glucocorticoid- treated mice
    • Yao W, Cheng Z, Busse C, Pham A, Nakamura MC, Lane NE,. Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice. Arthritis Rheum 2008; 58: 1674-86.
    • (2008) Arthritis Rheum , vol.58 , pp. 1674-1686
    • Yao, W.1    Cheng, Z.2    Busse, C.3    Pham, A.4    Nakamura, M.C.5    Lane, N.E.6
  • 43
    • 1942424854 scopus 로고    scopus 로고
    • Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: Novel mechanism of glucocorticoid-induced osteoporosis
    • Ohnaka K, Taniguchi H, Kawate H, Nawata H, Takayanagi R,. Glucocorticoid enhances the expression of dickkopf-1 in human osteoblasts: novel mechanism of glucocorticoid-induced osteoporosis. Biochem Biophys Res Commun 2004; 318: 259-64.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 259-264
    • Ohnaka, K.1    Taniguchi, H.2    Kawate, H.3    Nawata, H.4    Takayanagi, R.5
  • 44
    • 0032528180 scopus 로고    scopus 로고
    • Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids: Potential mechanisms of their deleterious effects on bone
    • Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC,. Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids: potential mechanisms of their deleterious effects on bone. J Clin Invest 1998; 102: 274-82.
    • (1998) J Clin Invest , vol.102 , pp. 274-282
    • Weinstein, R.S.1    Jilka, R.L.2    Parfitt, A.M.3    Manolagas, S.C.4
  • 45
    • 77953271453 scopus 로고    scopus 로고
    • Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice
    • Weinstein RS, Wan C, Liu Q, Wang Y, Almeida M, O'Brien CA, et al. Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice. Aging Cell 2010; 9: 147-61.
    • (2010) Aging Cell , vol.9 , pp. 147-161
    • Weinstein, R.S.1    Wan, C.2    Liu, Q.3    Wang, Y.4    Almeida, M.5    O'Brien, C.A.6
  • 46
    • 34548204415 scopus 로고    scopus 로고
    • Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival: Evidence for inside-out signaling leading to anoikis
    • Plotkin LI, Manolagas SC, Bellido T,. Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival: evidence for inside-out signaling leading to anoikis. J Biol Chem 2007; 282: 24120-30.
    • (2007) J Biol Chem , vol.282 , pp. 24120-24130
    • Plotkin, L.I.1    Manolagas, S.C.2    Bellido, T.3
  • 47
    • 2642583402 scopus 로고    scopus 로고
    • Osteocyte biology: Its implications for osteoporosis
    • Bonewald LF,. Osteocyte biology: its implications for osteoporosis. J Musculoskelet Neuronal Interact 2004; 4: 101-4.
    • (2004) J Musculoskelet Neuronal Interact , vol.4 , pp. 101-104
    • Bonewald, L.F.1
  • 48
    • 33744955055 scopus 로고    scopus 로고
    • Tumor necrosis factor-α increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression
    • Yao Z, Li P, Zhang Q, Schwarz EM, Keng P, Arbini A, et al. Tumor necrosis factor-α increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J Biol Chem 2006; 281: 11846-55.
    • (2006) J Biol Chem , vol.281 , pp. 11846-11855
    • Yao, Z.1    Li, P.2    Zhang, Q.3    Schwarz, E.M.4    Keng, P.5    Arbini, A.6
  • 49
    • 0035224983 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis
    • Weinstein RS,. Glucocorticoid-induced osteoporosis. Rev Endocr Metab Disord 2001; 2: 65-73.
    • (2001) Rev Endocr Metab Disord , vol.2 , pp. 65-73
    • Weinstein, R.S.1
  • 50
    • 0033984313 scopus 로고    scopus 로고
    • The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption
    • Hofbauer LC, Khosla S, Dunstan CR, Lacey DL, Boyle WJ, Riggs BL,. The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption. J Bone Miner Res 2000; 15: 2-12.
    • (2000) J Bone Miner Res , vol.15 , pp. 2-12
    • Hofbauer, L.C.1    Khosla, S.2    Dunstan, C.R.3    Lacey, D.L.4    Boyle, W.J.5    Riggs, B.L.6
  • 51
    • 0036020892 scopus 로고    scopus 로고
    • A direct approach to false discovery rates
    • Storey JD,. A direct approach to false discovery rates. J R Stat Soc Ser B 2002; 64: 479-98.
    • (2002) J R Stat Soc ser B , vol.64 , pp. 479-498
    • Storey, J.D.1


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