MRI and quantification of draining lymph node function in inflammatory arthritis

Annals of the New York Academy of Sciences

Volumn 1117, Issue , 2007, Pages 106-123

  Proulx, Steven T ^a   Kwok, Edmund ^b   You, Zhigang ^b   Beck, Christopher A ^b   Shealy, David J ^c   Ritchlin, Christopher T ^a   Boyce, Brendan F ^a   Xing, Lianping ^a   Schwarz, Edward M ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER   (United States)

^c CENTOCOR INC   (United States)

Author keywords

Animal model; In vivo imaging; Inflammatory arthritis; Lymph node; Lymphangiogenesis; MRI

Indexed keywords

TUMOR NECROSIS FACTOR ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; CONFERENCE PAPER; CONTRAST ENHANCEMENT; CONTROLLED STUDY; FEMALE; LYMPH NODE; LYMPHATIC DRAINAGE; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; SYNOVITIS; SYNOVIUM; WILD TYPE;

ANIMALIA; MUS;

EID: 36549000756     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1402.016     Document Type: Conference Paper

References (33)

1. FIRESTEIN, G.S. 2003. Evolving concepts of rheumatoid arthritis. Nature 423: 356-361.
2. FELDMANN, M. & R.N. MAINI. 2001. Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned? Annu. Rev. Immunol. 19: 163-196.
3. KEFFER, J. et al. 1991. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 10: 4025-4031.
4. LI, P. & E.M. SCHWARZ. 2003. The TNF-alpha transgenic mouse model of inflammatory arthritis. Springer Semin. Immunopathol. 25: 19-33.
5. HAYER, S. et al. 2007. Tenosynovitis and osteoclast formation as the initial preclinical changes in a murine model of inflammatory arthritis. Arthritis Rheum. 56: 79-88.
6. ALITALO, K., T. TAMMELA & T.V. PETROVA. 2005. Lymphangiogenesis in development and human disease. Nature 438: 946-953.
7. SWARTZ, M.A. 2001. The physiology of the lymphatic system. Adv. Drug Deliv. Rev. 50: 3-20.
8. DRAYTON, D.L. et al. 2006. Lymphoid organ development: from ontogeny to neogenesis. Nat. Immunol. 7: 344-353.
9. ANGELI, V. & G.J. RANDOLPH. 2006. Inflammation, lymphatic function, and dendritic cell migration. Lymphat. Res. Biol. 4: 217-228.
10. OLSZEWSKI, W.L. et al. 2001. Lymph draining from foot joints in rheumatoid arthritis provides insight into local cytokine and chemokine production and transport to lymph nodes. Arthritis Rheum. 44: 541-549.
11. HUH, Y.M. et al. 2005. The role of popliteal lymph nodes in differentiating rheumatoid arthritis from osteoarthritis by using CE 3D FSPGR MR imaging: relationship of the inflamed synovial volume. Korean J. Radiol. 6: 117-124.
12. SCHRODER, A.E. et al. 1996. Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 93: 221-225.
13. TAKEMURA, S. et al. 2001. Lymphoid neogenesis in rheumatoid synovitis. J. Immunol. 167: 1072-1080.
14. WEYAND, C.M., T.M. SEYLER & J.J. GORONZY. 2005. B cells in rheumatoid synovitis. Arthritis Res. Ther. 7(Suppl 3): S9-S12.
15. SHI, K. et al. 2001. Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients. J. Immunol. 166: 650-655.
16. CUENI, L.N. & M. DETMAR. 2006. New insights into the molecular control of the lymphatic vascular system and its role in disease. J. Invest. Dermatol. 126: 2167-2177.
17. PAAVONEN, K. et al. 2002. Vascular endothelial growth factors C and D and their VEGFR-2 and 3 receptors in blood and lymphatic vessels in healthy and arthritic synovium. J. Rheumatol. 29: 39-45.
18. WAUKE, K. et al. 2002. Expression and localization of vascular endothelial growth factor-C in rheumatoid arthritis synovial tissue. J. Rheumatol. 29: 34-38.
19. XU, H. et al. 2003. Distribution of lymphatic vessels in normal and arthritic human synovial tissues. Ann. Rheum. Dis. 62: 1227-1229.
20. HARRELL, M.I., B.M. IRITANI & A. RUDDELL. 2007. Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis. Am. J. Pathol. 170: 774-786.
21. QIAN, C.N. et al. 2006. Preparing the "soil": the primary tumor induces vasculature reorganization in the sentinel lymph node before the arrival of metastatic cancer cells. Cancer Res. 66: 10365-10376.
22. ANGELI, V. et al. 2006. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity 24: 203-215.
23. SHEALY, D.J. et al. 2002. Anti-TNF-alpha antibody allows healing of joint damage in polyarthritic transgenic mice. Arthritis Res. 4. R7.
24. PROULX, S. et al. 2006. 3D-MRI quantification of the progression and amelioration of inflammatory arthritis in mice. Arthritis Rheumatism 54: S621.
25. BOYCE, B.F. 1990. Bone biopsy and histomorphometry in metabolic bone disease. In New techniques in metabolic bone disease. J.C. Stevenson, Ed.: 110-131. Butterworths. London.
26. VAN DIJKE, C.F. et al. 1999. MR imaging of the arthritic rabbit knee joint using albumin-(Gd-DTPA)30 with correlation to histopathology. Magn. Reson. Imaging 17: 237-245.
27. BALUK, P. et al. 2005. Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation. J. Clin. Invest. 115: 247-257.
28. KAJIYA, K. & M. DETMAR. 2006. An important role of lymphatic vessels in the control of UVB-induced edema formation and inflammation. J. Invest. Dermatol. 126: 919-921.
29. THAUNAT, O., D. KERJASCHKI & A. NICOLETTI. 2006. Is defective lymphatic drainage a trigger for lymphoid neogenesis? Trends Immunol. 27: 441-445.
30. YOON, Y.S. et al. 2003. VEGF-C gene therapy augments postnatal lymphangiogenesis and ameliorates secondary lymphedema. J. Clin. Invest. 111: 717-725.
31. HERBORN, C.U. et al. 2002. Interstitial MR lymphography with MS-325: characterization of normal and tumor-invaded lymph nodes in a rabbit model. AJR Am. J. Roentgenol. 179: 1567-1572.
32. KOBAYASHI, H. et al. 2004. Lymphatic drainage imaging of breast cancer in mice by micro-magnetic resonance lymphangiography using a nano-size paramagnetic contrast agent. J. Natl. Cancer Inst. 96: 703-708.
33. TILNEY, N.L. 1971. Patterns of lymphatic drainage in the adult laboratory rat. J. Anat. 109: 369-383.