Terminal galactose residues on transferrin are increased in midlife adults compared to young adults

Proteomics

Volumn 12, Issue 21, 2012, Pages 3147-3153

  Dunston, Christopher R ^a   Choudhury, Khujesta ^a   Griffiths, Helen R ^a  

^a ASTON UNIVERSITY   (United Kingdom)

Author keywords

Biomarker; Glycoproteomics; N Acetyl neuraminic acid; N Glycosylation; Sialic acid

Indexed keywords

COMPLEMENT COMPONENT C3B; GALACTOSE; GLYCAN; N ACETYLNEURAMINIC ACID; PREALBUMIN; TRANSFERRIN;

ADULT; ARTICLE; CLINICAL ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; GALACTOSYLATION; GROUPS BY AGE; HUMAN; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

AGE FACTORS; BIOLOGICAL MARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GALACTOSE; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MALE; MIDDLE AGED; N-ACETYLNEURAMINIC ACID; PROTEOME; PROTEOMICS; TRANSFERRIN; YOUNG ADULT;

EID: 84868121725     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201100506     Document Type: Article

References (37)

1. Pérez-López, F. R., Chedraui, P., Haya, J., Cuadros, J. L., Effects of the Mediterranean diet on longevity and age-related morbid conditions. Maturitas 2009, 64, 67-79.
2. Hubbard, R. E., Fallah, N., Searle, S. D., Mitnitski, A. et al., Impact of exercise in community-dwelling older adults. PLoS One 2009, 4, e6174.
3. Lautenschlager, N. T., Cox, K., Cyarto, E. V., The influence of exercise on brain ageing and dementia. Biochim. Biophys. Acta. 2012, 1822, 474-481.
4. Finkelstein, M. M., Jerrett, M., Sears, M. R., Traffic air pollution and mortality rate advancement periods. Am. J. Epidemiol. 2004, 160, 173-177.
5. Bae, C.-Y., Kang, Y. G., Kim, S., Cho, C. et al., Development of models for predicting biological age (BA) with physical, biochemical, and hormonal parameters. Arch. Gerontol. Geriatr. 2008, 47, 253-265.
6. Holliday, R., The close relationship between biological and age-associated pathologies in humans. J. Gerontol. A Biol. Sci. Med. Sci. 2004, 59, B543-B546.
7. Butcher, S. K., Chahal, H., Nayak, L., Sinclair, A. et al., Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans. J. Leukoc. Biol. 2001, 70, 881-886.
8. Franceschi, C., Inflammaging as a major characteristic of old people: can it be prevented or cured? Nutr. Rev. 2007, 65, S173-S176.
9. Fagiolo, U., Cossarizza, A., Scala, E., Fanales-Belasio, E. et al., Increased cytokine production in mononuclear cells of healthy elderly people. Eur. J. Immunol. 1993, 23, 2375-2378.
10. Kim, H., Kim, H.-S., Youn, J.-C., Shin, E.-C. et al., Serum cytokine profiles in healthy young and elderly population assessed using multiplexed bead-based immunoassays. J. Transl. Med. 2011, 9, 113.
11. Seidler, S., Zimmermann, H., Bartneck, M., Trautwein, C. et al., Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults. BMC Immunol. 2010, 11, 30.
12. Antonelli, A., Rotondi, M., Fallahi, P., Ferrari, S. M. et al., Increase of CXC chemokine CXCL10 and CC chemokine CCL2 serum levels in normal ageing. Cytokine 2006, 34, 32-38.
13. Dunston, C. R., Griffiths, H. R., The effect of ageing on macrophage Toll-like receptor-mediated responses in the fight against pathogens. Clin. Exp. Immunol. 2010, 161, 407-416.
14. Martin-Ruiz, C. M., Gussekloo, J., van Heemst, D., von Zglinicki, T. et al., Telomere length in white blood cells is not associated with morbidity or mortality in the oldest old: a population-based study. Aging Cell 2005, 4, 287-290.
15. Kirkwood, T. B. L., Evolution of ageing. Nature 1977, 270, 301-304.
16. Cobon, G., Verrills, N., Papakostopoulos, P., Eastwood, H. et al., The proteomics of ageing. Biogerontology 2002, 3, 133-136.
17. Sharov, V. S., Schöneich, C., Proteomic approach to aging research. Expert Rev. Proteomics 2007, 4, 309-321.
18. Zhu, K., Zhao, J., Lubman, D. M., Miller, F. R. et al., Protein pI shifts due to posttranslational modifications in the separation and characterization of proteins. Anal. Chem. 2005, 77, 2745-2755.
19. Barrabés, S., Sarrats, A., Fort, E., De Llorens, R. et al., Effect of sialic acid content on glycoprotein pI analyzed by two-dimensional electrophoresis. Electrophoresis 2010, 31, 2903-2912.
20. Dunston, C. R., Griffiths, H. R., Lambert, P. A., Staddon, S. et al., Proteomic analysis of the anti-inflammatory action of minocycline. Proteomics 2011, 1, 42-51.
21. Magrane, M., Consortium, U., UniProt Knowledgebase: a hub of integrated protein data. Database (Oxford) 2011, http://www.uniprot.org/.
22. Gornik, O., Lauc, G., Enzyme linked lectin assay (ELLA) for direct analysis of transferrin sialylation in serum samples. Clin. Biochem. 2007, 40, 718-723.
23. Chen, R., Jiang, X., Sun, D., Han, G. et al., Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J. Proteome Res. 2009, 8, 651-661.
24. Liu, T., Qian, W.-J., Gritsenko, M. A., Camp, D. G. et al., Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. J. Proteome Res. 2005, 4, 2070-2080.
25. Gui, H.-L., Gao, C.-F., Wang, H., Liu, X.-E. et al., Altered serum N-glycomics in chronic hepatitis B patients. Liver Int. 2009, 30, 259-267.
26. Chen, C. C., Engelborghs, S., Dewaele, S., Le Bastard, N. et al., Altered serum glycomics in Alzheimer disease: a potential blood biomarker? Rejuvenation Res. 2011, 13, 439-444.
27. Vanhooren, V., Dewaele, S., Libert, C., Engelborghs, S. et al., Serum N-glycan profile shift during human ageing. Exp. Gerontol. 2010, 45, 738-743.
28. Ruhaak, L. R., Uh, H.-W., Beekman, M., Hokke, C. H. et al., Plasma protein N-glycan profiles are associated with calendar age, familial longevity and health. J. Proteome Res. 2011, 10, 1667-1674.
29. Bishop, G., Dang, T., Dringen, R., Robinson, S., Accumulation of non-transferrin-bound iron by neurons, astrocytes, and microglia. Neurotoxicity Res. 2011, 19, 443-451.
30. Loeffler, D. A., Connor, J. R., Juneau, P. L., Snyder, B. S. et al., Transferrin and iron in normal, Alzheimer's disease, and Parkinson's disease brain regions. J. Neurochem. 1995, 65, 710-716.
31. Smith, M. A., Zhu, X., Tabaton, M., Liu, G. et al., Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J. Alzheimer's Dis. 2010, 19, 363-372.
32. van Kamp, G. J., Mulder, K., Kuiper, M., Wolters, E. C., Changed transferrin sialylation in Parkinson's disease. Clin. Chim. Acta 1995, 235, 159-167.
33. Potter, B. J., McHugh, T. A., Beloqui, O., Iron uptake from transferrin and asialotransferrin by hepatocytes from chronically alcohol-fed rats. Alcohol. Clin. Exp. Res. 1992, 16, 810-815.
34. Ward, W., Richardson, A., Effect of age on liver protein synthesis and degradation. Hepatology 1991, 14, 935-948.
35. Allalouf, D., Komlos, L., Notmann, J., Halbrecht, I., et al., Sialic acid content and sialyltransferase activity in human lymphocytes with advancing age. Mech. Ageing Dev. 1988, 44, 45-50.
36. Spataro, A. C., Bosmann, H. B., Myers-Robfogel, M. W., Sialyltransferase activities of aging diploid fibroblasts. Biochim. Biophys. Acta 1979, 553, 378-387.
37. Kleinert, P., Kuster, T., Durka, S., Ballhausen, D. et al., Mass spectrometric analysis of human transferrin in different body fluids. Clin. Chem. Lab. Med. 2003, 41, 1580-1588.