Conservation of the DENV-2 type-specific and DEN complex-reactive antigenic sites among DENV-2 genotypes

Virology

Volumn 422, Issue 2, 2012, Pages 386-392

  Pitcher, Trevor J ^a,b,c   Gromowski, Gregory D ^a,b,c   Beasley, David W C ^a,b   Barrett, Alan D T ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Antibody mediated neutralization; Antigenic sites; DENV 2 genotypes

Indexed keywords

ENVELOPE PROTEIN; ENVELOPE PROTEIN ED3; MONOCLONAL ANTIBODY; RECOMBINANT ENVELOPE PROTEIN ED3; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIBODY SPECIFICITY; ARTICLE; BINDING AFFINITY; DENGUE; DENGUE VIRUS; DENGUE VIRUS 2; GENOTYPE; IMMUNE RESPONSE; NONHUMAN; PRIORITY JOURNAL; VIRUS EXPRESSION; VIRUS NEUTRALIZATION; VIRUS STRAIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIBODY AFFINITY; ANTIGENS, VIRAL; CERCOPITHECUS AETHIOPS; DENGUE VIRUS; GENE EXPRESSION REGULATION, VIRAL; GENOTYPE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; VERO CELLS; VIRAL PROTEINS;

EID: 84855195471     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2011.10.020     Document Type: Article

References (31)

1. Allison S.L., Schalich J., Stiasny K., Mandl C.W., Heinz F.X. Mutational evidence for an internal fusion peptide in flavivirus envelope protein E. J. Virol. 2001, 75(9):4268-4275.
2. Brien J.D., Austin S.K., Sukupolvi-Petty S., O'Brien K.M., Johnson S., Fremont D.H., Diamond M.S. Genotype-specific neutralization and protection by antibodies against dengue virus type 3. J. Virol. 2010, 84(20):10630-10643.
3. Chambers T.J., Hahn C.S., Galler R., Rice C.M. Flavivirus genome organization, expression, and replication. Annu. Rev. Microbiol. 1990, 44:649-688.
4. Chin J.F., Chu J.J., Ng M.L. The envelope glycoprotein domain III of dengue virus serotypes 1 and 2 inhibit virus entry. Microbes Infect. 2007, 9(1):1-6.
5. Crill W.D., Roehrig J.T. Monoclonal antibodies that bind to domain III of dengue virus E glycoprotein are the most efficient blockers of virus adsorption to Vero cells. J. Virol. 2001, 75(16):7769-7773.
6. Gentry M.K., Henchal E.A., McCown J.M., Brandt W.E., Dalrymple J.M. Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies. Am. J. Trop. Med. Hyg. 1982, 31(3 Pt 1):548-555.
7. Gromowski G.D., Barrett A.D. Characterization of an antigenic site that contains a dominant, type-specific neutralization determinant on the envelope protein domain III (ED3) of dengue 2 virus. Virology 2007, 366(2):349-360.
8. Gromowski G.D., Barrett N.D., Barrett A.D. Characterization of dengue virus complex-specific neutralizing epitopes on envelope protein domain III of dengue 2 virus. J. Virol. 2008, 82(17):8828-8837.
9. Gromowski G.D., Roehrig J.T., Diamond M.S., Lee J.C., Pitcher T.J., Barrett A.D. Mutations of an antibody binding energy hot spot on domain III of the dengue 2 envelope glycoprotein exploited for neutralization escape. Virology 2010, 407(2):237-246.
10. Hung J.J., Hsieh M.T., Young M.J., Kao C.L., King C.C., Chang W. An external loop region of domain III of dengue virus type 2 envelope protein is involved in serotype-specific binding to mosquito but not mammalian cells. J. Virol. 2004, 78(1):378-388.
11. Kaufmann B., Nybakken G.E., Chipman P.R., Zhang W., Diamond M.S., Fremont D.H., Kuhn R.J., Rossmann M.G. West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody. Proc. Natl. Acad. Sci. U. S. A. 2006, 103(33):12400-12404.
12. Kuhn R.J., Zhang W., Rossmann M.G., Pletnev S.V., Corver J., Lenches E., Jones C.T., Mukhopadhyay S., Chipman P.R., Strauss E.G., Baker T.S., Strauss J.H. Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell 2002, 108(5):717-725.
13. Kyle J.L., Harris E. Global spread and persistence of dengue. Annu. Rev. Microbiol. 2008, 62:71-92.
14. Leitmeyer K.C., Vaughn D.W., Watts D.M., Salas R., Villalobos I., de C., Ramos C., Rico-Hesse R. Dengue virus structural differences that correlate with pathogenesis. J. Virol. 1999, 73(6):4738-4747.
15. Lok S.M., Kostyuchenko V., Nybakken G.E., Holdaway H.A., Battisti A.J., Sukupolvi-Petty S., Sedlak D., Fremont D.H., Chipman P.R., Roehrig J.T., Diamond M.S., Kuhn R.J., Rossmann M.G. Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat. Struct. Mol. Biol. 2008, 15(3):312-317.
16. Matsui K., Gromowski G.D., Li L., Barrett A.D. Characterization of a dengue type-specific epitope on dengue 3 virus envelope protein domain III. J. Gen. Virol. 2010, 91(Pt 9):2249-2253.
17. Matsui K., Gromowski G.D., Li L., Schuh A.J., Lee J.C., Barrett A.D. Characterization of dengue complex-reactive epitopes on dengue 3 virus envelope protein domain III. Virology 2009, 384(1):16-20.
18. Nybakken G.E., Oliphant T., Johnson S., Burke S., Diamond M.S., Fremont D.H. Structural basis of West Nile virus neutralization by a therapeutic antibody. Nature 2005, 437(7059):764-769.
19. Pierson T.C., Fremont D.H., Kuhn R.J., Diamond M.S. Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development. Cell Host Microbe 2008, 4(3):229-238.
20. Rey F.A., Heinz F.X., Mandl C., Kunz C., Harrison S.C. The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution. Nature 1995, 375(6529):291-298.
21. Rice C.M., Lenches E.M., Eddy S.R., Shin S.J., Sheets R.L., Strauss J.H. Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution. Science 1985, 229(4715):726-733.
22. Rico-Hesse R., Harrison L.M., Salas R.A., Tovar D., Nisalak A., Ramos C., Boshell J., de Mesa M.T., Nogueira R.M., da Rosa A.T. Origins of dengue type 2 viruses associated with increased pathogenicity in the Americas. Virology 1997, 230(2):244-251.
23. Roehrig J.T., Bolin R.A., Kelly R.G. Monoclonal antibody mapping of the envelope glycoprotein of the dengue 2 virus, Jamaica. Virology 1998, 246(2):317-328.
24. Sabin A.B. Research on dengue during World War II. Am. J. Trop. Med. Hyg. 1952, 1(1):30-50.
25. Shrestha B., Brien J.D., Sukupolvi-Petty S., Austin S.K., Edeling M.A., Kim T., O'Brien K.M., Nelson C.A., Johnson S., Fremont D.H., Diamond M.S. The development of therapeutic antibodies that neutralize homologous and heterologous genotypes of dengue virus type 1. PLoS Pathog. 2010, 6(4):e1000823.
26. Sukupolvi-Petty S., Austin S.K., Engle M., Brien J.D., Dowd K.A., Williams K.L., Johnson S., Rico-Hesse R., Harris E., Pierson T.C., Fremont D.H., Diamond M.S. Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2. J. Virol. 2010, 84(18):9227-9239.
27. Sukupolvi-Petty S., Austin S.K., Purtha W.E., Oliphant T., Nybakken G.E., Schlesinger J.J., Roehrig J.T., Gromowski G.D., Barrett A.D., Fremont D.H., Diamond M.S. Type- and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes. J. Virol. 2007, 81(23):12816-12826.
28. Throsby M., Geuijen C., Goudsmit J., Bakker A.Q., Korimbocus J., Kramer R.A., Clijsters-van der Horst M., de Jong M., Jongeneelen M., Thijsse S., Smit R., Visser T.J., Bijl N., Marissen W.E., Loeb M., Kelvin D.J., Preiser W., ter Meulen J., de Kruif J. Isolation and characterization of human monoclonal antibodies from individuals infected with West Nile Virus. J. Virol. 2006, 80(14):6982-6992.
29. Twiddy S.S., Farrar J.J., Vinh Chau N., Wills B., Gould E.A., Gritsun T., Lloyd G., Holmes E.C. Phylogenetic relationships and differential selection pressures among genotypes of dengue-2 virus. Virology 2002, 298(1):63-72.
30. Wahala W.M., Donaldson E.F., de Alwis R., Accavitti-Loper M.A., Baric R.S., de Silva A.M. Natural strain variation and antibody neutralization of dengue serotype 3 viruses. PLoS Pathog. 2010, 6(3):e1000821.
31. Watts D.M., Porter K.R., Putvatana P., Vasquez B., Calampa C., Hayes C.G., Halstead S.B. Failure of secondary infection with American genotype dengue 2 to cause dengue haemorrhagic fever. Lancet 1999, 354(9188):1431-1434.