Human monoclonal antibodies against west nile virus induced by natural infection neutralize at a postattachment step

Journal of Virology

Volumn 83, Issue 13, 2009, Pages 6494-6507

  Vogt, Matthew R ^a   Moesker, Bastiaan ^b   Goudsmit, Jaap ^c   Jongeneelen, Mandy ^c   Austin, S Kyle ^a   Oliphant, Theodore ^a   Nelson, Steevenson ^d   Pierson, Theodore C ^d   Wilschut, Jan ^b   Throsby, Mark ^c   Diamond, Michael S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c CRUCELL HOLLAND BV   (Netherlands)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CR4348; MONOCLONAL ANTIBODY CR4354; MONOCLONAL ANTIBODY HU E16; NEUTRALIZING ANTIBODY; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DRUG POTENCY; ENDOSOME; EPIDEMIC; HUMAN; HUMORAL IMMUNITY; IN VIVO STUDY; MOUSE; NONHUMAN; NORTH AMERICA; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; VIRION; VIROGENESIS; VIRUS ATTACHMENT; VIRUS ENCEPHALITIS; VIRUS INFECTION; VIRUS MUTATION; VIRUS NEUTRALIZATION; VIRUS PARTICLE; WEST NILE FLAVIVIRUS; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; CELL LINE; ENZYME SPECIFICITY; EPITOPE MAPPING; GENETICS; IMMUNOLOGY; PROTEIN TERTIARY STRUCTURE; SERODIAGNOSIS;

FLAVIVIRUS; MUS; WEST NILE VIRUS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, VIRAL; ANTIBODY SPECIFICITY; B-LYMPHOCYTES; CELL LINE; EPITOPE MAPPING; HUMANS; MICE; MICE, INBRED C57BL; NEUTRALIZATION TESTS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; VIRAL ENVELOPE PROTEINS; WEST NILE FEVER; WEST NILE VIRUS;

EID: 67449096209     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00286-09     Document Type: Article

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