Synthesis, Cytotoxicity, and Cell Death Profile of Polyaminoanthraquinones as Antitumor Agents

Chemical Biology and Drug Design

Volumn 80, Issue 6, 2012, Pages 909-917

  Wang, Jianhong ^a   Gao, Ruihong ^a   Li, Qian ^a   Xie, Songqiang ^a   Zhao, Jin ^a   Wang, Chaojie ^a  

^a HENAN UNIVERSITY   (China)

Author keywords

Anthraquinone; Apoptosis; Cell death; Mechanism; Necrosis; Polyamine; Synthesis

Indexed keywords

1 (3 HYDROXYL PROPYLAMINO) 9,10 ANTHRAQUINONE; 1 [(2 N,N BISMETHYLAMINO)ETHYLAMINO] 9, 10 ANTHRAQUINONE; 1 [3 (2 AMINO ETHYLAMINO) 2 HYDROXYLPROPYLAMINO] 9,10 ANTHRAQUINONE; 1 [3 (3 AMINO PROPYLAMINO) 2 HYDROXYLPROPYLAMINO] 9,10 ANTHRAQUINONE; 1 [3 (4 AMINO BUTYLAMINO) 2 HYDROXYLPROPYLAMINO] 9,10 ANTHRAQUINONE; 1 [3 [3 (4 AMINO BUTYLAMINO) 2 HYDROXYLPROPYLAMINO)] 9,10 ANTHRAQUINONE; 1 [3 [3 (4 AMINO BUTYLAMINO) BUTYLAMINO 2 HYDROXYLPROPYLAMINO)] 9,10 ANTHRAQUINONE; 1 CHLORO 8 [(2 N,N BISMETHYLAMINO)ETHYLAMINO] 9, 10 ANTHRAQUINONE; ANTHRAQUINONE DERIVATIVE; ANTINEOPLASTIC AGENT; CASPASE 3; CYTOCHROME C; MITOXANTRONE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LYSOSOME; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN MOTIF;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; HCT116 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; K562 CELLS;

EID: 84868109309     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/cbdd.12038     Document Type: Article

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