BCL2A1a Over-Expression in Murine Hematopoietic Stem and Progenitor Cells Decreases Apoptosis and Results in Hematopoietic Transformation

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Métais, Jean Yves ^a   Winkler, Thomas ^a   Geyer, Julia T ^b   Calado, Rodrigo T ^a,c   Aplan, Peter D ^d   Eckhaus, Michael A ^e   Dunbar, Cynthia E ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d NATIONAL CANCER INSTITUTE   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BCL2 RELATED PROTEIN A1; BCL2 RELATED PROTEIN A1A; LENTIVIRUS VECTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; BCL2A1A GENE; CELL ASSAY; CELL CYCLE; CELL GROWTH; CELL KINETICS; CELL TRANSFORMATION; CLONAL VARIATION; CONTROLLED STUDY; DISEASE FREE SURVIVAL; GENE OVEREXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA; LEUKEMOGENESIS; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTO ONCOGENE; STEM CELL GENE THERAPY; SURVIVAL RATE;

ANIMALS; APOPTOSIS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSDUCTION, GENETIC; TUMOR BURDEN;

MURINAE; MUS; PRIMATES;

EID: 84868091981     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048267     Document Type: Article

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