Feline leukemia virus integrase and capsid packaging functions do not change the insertion profile of standard Moloney retroviral vectors

Gene Therapy

Volumn 17, Issue 6, 2010, Pages 799-804

  Metais J Y ^a   Topp, S ^a,b   Doty, R T ^c   Borate, B ^d   Nguyen, A D ^d   Wolfsberg, T G ^d   Abkowitz, J L ^c   Dunbar, C E ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

Feline leukemia virus; Insertion site analysis; Retroviral vector; Viral packaging machinery

Indexed keywords

GAG PROTEIN; GENE PRODUCT; INTEGRASE; NUCLEOTIDE; POL PROTEIN; PROTEIN LMO 2; RETROVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; CAPSID PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ARTICLE; CD34 SELECTION; COMPUTER ANALYSIS; CONTROLLED STUDY; DNA PACKAGING; FELINE LEUKEMIA VIRUS; GENE EXPRESSION REGULATION; GENE INSERTION; GENETIC TRANSDUCTION; GENOTOXICITY; HEMATOPOIETIC STEM CELL; MOLONEY LEUKEMIA ONCOVIRUS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RHESUS MONKEY; TRANSCRIPTION INITIATION SITE; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID; VIRUS DNA CELL DNA INTERACTION; X LINKED SEVERE COMBINED IMMUNODEFICIENCY; ANIMAL; GENE TRANSFER; GENE VECTOR; GENETICS; METABOLISM; VIROLOGY;

ANIMALIA; FELINE LEUKEMIA VIRUS; MACACA MULATTA; MIRIDAE; SIMIAN IMMUNODEFICIENCY VIRUS;

ANIMALS; CAPSID; CAPSID PROTEINS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEMATOPOIETIC STEM CELLS; INTEGRASES; LEUKEMIA VIRUS, FELINE; MACACA MULATTA; MOLONEY MURINE LEUKEMIA VIRUS; TRANSDUCTION, GENETIC; VIRUS INTEGRATION;

EID: 77953409590     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2010.24     Document Type: Article

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