The association between soluble lectin-like oxidized low-density lipoprotein receptor-1 levels and patients with isolated coronary artery ectasia

Journal of Thrombosis and Thrombolysis

Volumn 33, Issue 3, 2012, Pages 239-245

  Balin, Mehmet ^a   Celik, Ahmet ^a   Kobat, M Ali ^a  

^a Elazig Education and Research Hospital ^*  (Turkey)

Author keywords

Coronary artery ectasia; Normal coronary arteries; Soluble lectin like oxidized low density lipoprotein receptor 1; Types of ectasia

Indexed keywords

CREATININE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; TRIACYLGLYCEROL; BIOLOGICAL MARKER;

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CASE CONTROL STUDY; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY ECTASIA; CORONARY ARTERY OBSTRUCTION; CREATININE BLOOD LEVEL; DIET RESTRICTION; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; ISOLATED CORONARY ARTERY ECTASIA; LIPID BLOOD LEVEL; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; COMPARATIVE STUDY; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; LESIONS AND DEFECTS; MIDDLE AGED; PATHOLOGY;

BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; CORONARY VESSELS; DILATATION, PATHOLOGIC; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SCAVENGER RECEPTORS, CLASS E;

EID: 84868091824     PISSN: 09295305     EISSN: 1573742X     Source Type: Journal    
DOI: 10.1007/s11239-011-0668-4     Document Type: Article

References (75)

1. Swaye PS, Fisher LD, Litwin P, Vignola PA, Judkins MP, Kemp HG, Mudd JG, Gosselin AJ (1983) Aneurysmal coronary artery disease. Circulation 67:134-138
2. Falsetti HL, Carrol RJ (1976) Coronary artery aneurysm. A review of the literature with a report of 11 new cases. Chest 69:630-636
3. Sorrell VL, Davis MJ, Bove AA (1998) Current knowledge and significance of coronary artery ectasia: A chronologic review of the literature, recommendations for treatment, possible etiologies, and future considerations. Clin Cardiol 21:157-160
4. Giannoglou GD, Antoniadis AP, Chatzizisis YS, Damvopoulou E, Parcharidis GE, Louridas GE (2006) Prevalence of ectasia in human coronary arteries in patients in northern Greece referred for coronary angiography. Am J Cardiol 98:314-318
5. Kruger D, Stierle U, Herrmann G, Simon R, Sheikhzadeh A (1999) Exercise-induced myocardial ischemia in isolated coronary artery ectasias and aneurysms ("dilated coronopathy"). J Am Coll Cardiol 34:1461-1470
6. Jang IK, Lassila R, Fuster V (1993) Atherogenesis and inflammation. Eur Heart J 14(Suppl K):2-6
7. Haught WH, Mansour M, Rothlein R, Kishimoto TK, Mainolfi EA, Hendricks JB, Hendricks C, Mehta JL (1996) Alterations in circulating intercellular adhesion molecule-1 and L-selectin: Further evidence for chronic inflammation in ischemic heart disease. Am Heart J 132:1-8
8. Ozeren A, Aydin M, Tokac M, Demircan N, Unalacak M, Gurel A, Yazici M (2003) Levels of serum IL-1beta, IL-2, IL-8 and tumor necrosis factor-alpha in patients with unstable angina pectoris. Mediators Inflamm 12:361-365
9. Markis JE, Joffe CD, Cohn PF, Feen DJ, Herman MV, Gorlin R (1976) Clinical significance of coronary arterial ectasia. Am J Cardiol 37:217-222
10. Kajinami K, Kasashima S, Oda Y, Koizumi J, Katsuda S, Mabuchi H (1999) Coronary ectasia in familial hypercholesterolemia: Histopathologic study regarding matrix metalloproteinases. Mod Pathol 12:1174-1180
11. Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, Tanaka T, Miwa S, Katsura Y, Kita T, Masaki T (1997) An endothelial receptor for oxidized low-density lipoprotein. Nature 386:73-77
12. Yoshida H, Kondratenko N, Green S, Steinberg D, Quehenberger O (1998) Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor. Biochem J 334:9-13
13. Vohra RS, Murphy JE, Walker JH, Ponnambalam S, Homer-Vanniasinkam S (2006) Atherosclerosis and the lectin-like oxidized low-density lipoprotein scavenger receptor. Trends Cardiovasc Med 16:60-64
14. Mehta JL, Chen J, Hermonat PL, Romeo F, Novelli G (2006) Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): A critical player in the development of atherosclerosis and related disorders. Cardiovasc Res 69:36-45
15. Oka K, Sawamura T, Kikuta K, Itokawa S, Kume N, Kita T, Masaki T (1998) Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells. Proc Natl Acad Sci USA 95:9535-9540
16. Kakutani M, Masaki T, Sawamura T (2000) A platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1. Proc Natl Acad Sci USA 97:360-364
17. Honjo M, Nakamura K, Yamashiro K, Kiryu J, Tanihara H, McEvoy LM, Honda Y, Butcher EC, Masaki T, Sawamura T (2003) Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation. Proc Natl Acad Sci USA 100:1274-1279
18. Fujita Y, Kakino A, Nishimichi N, Yamaguchi S, Sato Y, Machida S, Cominacini L, Delneste Y, Matsuda H, Sawamura T (2009) Oxidized LDL receptor LOX-1 binds to C-reactive protein and mediates its vascular effects. Clin Chem 55:285-294
19. Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, Satoh H, Inoue K, Kawase Y, Jishage K, Suzuki H, Takeya M, Schnackenberg L, Beger R, Hermonat PL, Thomas M, Sawamura T (2007) Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res 100:1634-1642
20. Inoue K, Arai Y, Kurihara H, Kita T, Sawamura T (2005) Overexpression of lectin-like oxidized low-density lipoprotein receptor-1 induces intramyocardial vasculopathy in apolipoprotein E-null mice. Circ Res 97:176-184
21. Nakagawa T, Akagi M, Hoshikawa H, Chen M, Yasuda T, Mukai S, Ohsawa K, Masaki T, Nakamura T, Sawamura T (2002) Lectin-like oxidized low-density lipoprotein receptor 1 mediates leukocyte infiltration and articular cartilage destruction in rat zymosan-induced arthritis. Arthritis Rheum 46:2486-2494
22. Asplund K (2002) Antioxidant vitamins in the prevention of cardiovascular disease: A systematic review. J Intern Med 251:372-392
23. Kataoka K, Hasegawa K, Sawamura T, Fujita M, Yanazume T, Iwai-Kanai E, Kawamura T, Hirai T, Kita T, Nohara R (2003) LOX-1 pathway affects the extent of myocardial ischemia-reperfusion injury. Biochem Biophys Res Commun 300:656-660
24. Hinagata J, Kakutani M, Fujii T, Naruko T, Inoue N, Fujita Y, Mehta JL, Ueda M, Sawamura T (2006) Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. Cardiovasc Res 69:263-271
25. Murase T, Kume N, Kataoka H, Minami M, Sawamura T, Masaki T, Kita T (2000) Identification of soluble forms of lectin-like oxidized LDL receptor-1. Arterioscler Thromb Vasc Biol 20:715-720
26. Hayashida K, Kume N, Murase T, Minami M, Nakagawa D, Inada T, Tanaka M, Ueda A, Kominami G, Kambara H, Kimura T, Kita T (2005) Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: A novel marker for early diagnosis. Circulation 112:812-818
27. Tan KC, Shiu SW, Wong Y, Leng L, Bucala R (2008) Soluble lectin-like oxidized low density lipoprotein receptor-1 in type 2diabetes mellitus. J Lipid Res 49:1438-1444
28. Brinkley TE, Kume N, Mitsuoka H, Phares DA, Hagberg JM (2008) Elevated soluble lectin-like oxidized LDL receptor-1 (sLOX-1) levels in obese postmenopausal women. Obesity 16:1454-1456
29. Ueda A, Kume N, Hayashida K, Inui-Hayashida A, Asai M, Kita T, Kominami G (2006) ELISA for soluble form of lectin-like oxidized LDL receptor-1, a novel marker of acute coronary syndrome. Clin Chem 52:1210-1211
30. Markis JE, Joffe CD, Cohn PF, Feen DJ, Herman MV, Gorlin R (1976) Clinical significance of coronary arterial ectasia. Am J Cardiol 37:217-222
31. Li JJ (2005) Inflammation: An important mechanism for different clinical entities of coronary artery diseases. Chin Med J (Engl) 118:1817-1826
32. Li JJ (2004) Silent myocardial ischemia may be related to inflammatory response. Med Hypotheses 62:252-256
33. Li JJ, Nie SP, Xu B, Guo YL, Gao Z, Zheng X (2007) Inflammation in variant angina: Is there any evidence? Med Hypotheses 68:635-640
34. Dawson J, Cockerill GW, Choke E, Belli AM, Loftus I, Thompson MM (2007) Aortic aneurysms secrete interleukin-6 into the circulation. J Vasc Surg 45:350-356
35. Tokgozoglu L, Ergene O, Kinay O, Nazli C, Hascelik G, Hoscan Y (2004) Plasma interleukin-6 levels are increased in coronary artery ectasia. Acta Cardiol 59:515-519
36. Yildirim N, Tekin IO, Dogan SM, Aydin M, Gursurer M, Cam F, Gungorduk A, Akoz A (2007) Expression of monocyte and lymphocyte adhesion molecules is increased in isolated coronary artery ectasia. Coron Artery Dis 18:49-53
37. Yilmaz H, Tayyareci G, Sayar N, Gurkan U, Tangurek B, Asilturk R, Ozer N, Aksoy S, Simsek D, Yilmaz M, Engin O, Cagil A (2006) Plasma soluble adhesion molecule levels in coronary artery ectasia. Cardiology 105:176-181
38. Chen J, Mehta JL (2004) Role of oxidative stress in coronary heart disease. Indian Heart J 56:163-173
39. Sugano M, Tsuchida K, Makino N (2004) Effects of soluble TNF-alpha receptor 1 on apoptosis induced by oxidized LDL in endothelial cells. Mol Cell Biochem 258:57-63
40. Nagase M, Ando K, Nagase T, Kaname S, Sawamura T, Fujita T (2001) Redox-sensitive regulation of LOX-1 gene expression in vascular endothelium. Biochem Biophys Res Commun 281:720-725
41. Nagase M, Hirose S, Sawamura T, Masaki T, Fujita T (1997) Enhanced expression of endothelial oxidized low-density lipoprotein receptor (LOX-1) in hypertensive rats. Biochem Biophys Res Commun 237:496-498
42. Chen M, Nagase M, Fujita T, Narumiya S, Masaki T, Sawamura T (2001) Diabetes enhances lectin-like oxidized LDL receptor-1 (LOX-1) expression in the vascular endothelium: Possible role of LOX-1 ligand and AGE. Biochem Biophys Res Commun 287:962-968
43. Chen H, Li D, Sawamura T, Inoue K, Mehta JL (2000) Upregulation of LOX-1 expression in aorta of hypercholesterolemic rabbits: Modulation by losartan. Biochem Biophys Res Commun 276:1100-1104
44. Newby AC, Southgate KM, Davies M (1994) Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis. Basic Res Cardiol 89(Suppl 1):59-70
45. Li YY, McTiernan CF, Feldman AM (2000) Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases, and their regulators in cardiac matrix remodeling. Cardiovasc Res 46:214-224
46. Rouis M, Adamy C, Duverger N, Lesnik P, Horellou P, Moreau M, Emmanuel F, Caillaud JM, Laplaud PM, Dachet C, Chapman MJ (1999) Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinase-1 reduces atherosclerotic lesions in apolipoprotein E-deficient mice. Circulation 100:533-540
47. Pasterkamp G, Schoneveld AH, Hijnen DJ, de Kleijn DP, Teepen H, van der Wal AC, Borst C (2000) Atherosclerotic arterial remodeling and the localization of macrophages and matrix metalloproteases 1, 2 and 9 in the human coronary artery. Atherosclerosis 150:245-253
48. Peterson JT, Hallak H, Johnson L, Li H, O'Brien PM, Sliskovic DR, Bocan TM, Coker ML, Etoh T, Spinale FG (2001) Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure. Circulation 103:2303-2309
49. Silence J, Lupu F, Collen D, Lijnen HR (2001) Persistence of atherosclerotic plaque but reduced aneurysm formation in mice with stromelysin-1 (MMP-3) gene inactivation. Arterioscler Thromb Vasc Biol 21:1440-1445
50. Lemaître V, O'Byrne TK, Borczuk AC, Okada Y, Tall AR, D'Armiento J (2001) ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis. J Clin Invest 107:1227-1234
51. Ehara S, Ueda M, Naruko T, Haze K, Itoh A, Otsuka M, Komatsu R, Matsuo T, Itabe H, Takano T, Tsukamoto Y, Yoshiyama M, Takeuchi K, Yoshikawa J, Becker AE (2001) Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 103:1955-1960
52. Kume N, Murase T, Moriwaki H, Aoyama T, Sawamura T, Masaki T, Kita T (1998) Inducible expression of lectin-like oxidized LDL receptor-1 in vascular endothelial cells. Circ Res 83:322-327
53. Li DY, Zhang YC, Philips MI, Sawamura T, Mehta JL (1999) Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor activation. Circ Res 84:1043-1049
54. Li L, Sawamura T, Renier G (2003) Glucose enhances endothelial LOX-1 expression: Role for LOX-1 in glucose-induced human monocyte adhesion to endothelium. Diabetes 52:1843-1850
55. Kataoka H, Kume N, Miyamoto S, Minami M, Morimoto M, Hayashida K, Hashimoto N, Kita T (2001) Oxidized LDL modulates Bax/Bcl-2 through the lectin like ox-LDL receptor-1 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 21:955-960
56. Moriwaki H, Kume N, Kataoka H, Murase T, Nishi E, Sawamura T, Masaki T, Kita T (1998) Expression of lectin-like oxidized low density lipoprotein receptor-1 in human and murine macrophages: Upregulated expression by TNF-alpha. FEBS Lett 440:29-32
57. Kataoka H, Kume N, Miyamoto S, Minami M, Moriwaki H, Murase T, Sawamura T, Masaki T, Hashimoto N, Kita T (1999) Expression of lectin like oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions. Circulation 99:3110-3117
58. Kataoka H, Kume N, Miyamoto S, Minami M, Murase T, Sawamura T, Masaki T, Hashimoto N, Kita T (2000) Biosynthesis and post-translational processing of lectin-like oxidized low density lipoprotein receptor-1 (LOX-1). N-linked glycosylation affects cell-surface expression and ligand binding. J Biol Chem 275:6573-6579
59. Li DY, Chen HJ, Mehta JL (2001) Statins inhibit oxidized-LDLmediated LOX-1 expression, uptake of oxidized-LDL and reduction in PKB phosphorylation. Cardiovasc Res 52:130-135
60. Cominacini L, Pasini AF, Garbin U, Davoli A, Tosetti ML, Campagnola M, Rigoni A, Pastorino AM, Lo Cascio V, Sawamura T (2000) Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species. J Biol Chem 275:12633-12638
61. Li D, Mehta JL (2000) Upregulation of endothelial receptor for oxidized LDL (LOX-1) by oxidized LDL and implications in apoptosis of human coronary artery endothelial cells: Evidence from use of antisense LOX-1 mRNA and chemical inhibitors. Arterioscler Thromb Vasc Biol 20:1116-1122
62. Terasaka N, Wang N, Yvan-Charvet L, Tall AR (2007) Highdensity lipoprotein protects macrophages from oxidized lowdensity lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1. Proc Natl Acad Sci USA 104: 15093-15098
63. Li D, Mehta JL (2000) Antisense to LOX-1 inhibits oxidized LDL-mediated upregulation of monocyte chemoattractant protein-1 and monocyte adhesion to human coronary artery endothelial cells. Circulation 101:2889-2895
64. Li D, Liu L, Chen H, Sawamura T, Mehta JL (2003) LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. Arterioscler Thromb Vasc Biol 23:816-821
65. Li D, Liu L, Chen H, Sawamura T, Ranganathan S, Mehta JL (2003) LOX-1 mediates oxidized low-density lipoproteininduced expression of matrix metalloproteinases in human coronary artery endothelial cells. Circulation 107:612-617
66. Cominacini L, Rigoni A, Pasini AF, Garbin U, Davoli A, Campagnola M, Pastorino AM, Lo Cascio V, Sawamura T (2001) The binding of oxidized low density lipoprotein (ox-LDL) to ox-LDL receptor-1 reduces the intracellular concentration of nitric oxide in endothelial cells through an increased production of superoxide. J Biol Chem 276:13750-13755
67. Sakurai K, Cominacini L, Garbin U, Fratta Pasini A, Sasaki N, Takuwa Y, Masaki T, Sawamura T (2004) Induction of endothelin-1 production in endothelial cells via co-operative action between CD40 and lectin-like oxidized LDL receptor (LOX-1). J Cardiovasc Pharmacol 44(Suppl 1):S173-180
68. Szmitko PE, Wang CH, Weisel RD, Jeffries GA, Anderson TJ, Verma S (2003) Biomarkers of vascular disease linking inflammation to endothelial activation: Part II. Circulation 108:2041-2048
69. Ishino S, Mukai T, Kume N, Asano D, Ogawa M, Kuge Y, Minami M, Kita T, Shiomi M, Saji H (2007) Lectin-like oxidized LDL receptor-1 (LOX-1) expression is associated with atherosclerotic plaque instability-analysis in hypercholesterolemic rabbits. Atherosclerosis 195:48-56
70. Kuge Y, Kume N, Ishino S, Takai N, Ogawa Y, Mukai T, Minami M, Shiomi M, Saji H (2008) Prominent lectin-like oxidized low density lipoprotein (LDL) receptor-1 (LOX-1) expression in atherosclerotic lesions is associated with tissue factor expression and apoptosis in hypercholesterolemic rabbits. Biol Pharm Bull 31:1475-1482
71. Ishino S, Mukai T, Kuge Y, Kume N, Ogawa M, Takai N, Kamihashi J, Shiomi M, Minami M, Kita T, Saji H (2008) Targeting of lectin like oxidized low-density lipoprotein receptor 1 (LOX-1) with 99mTc-labeled anti-LOX-1 antibody: Potential agent for imaging of vulnerable plaque. J Nucl Med 49:1677-1685
72. Li L, Roumeliotis N, Sawamura T, Renier G (2004) C-reactive protein enhances LOX-1 expression in human aortic endothelial cells: Relevance of LOX-1 to C-reactive protein-induced endothelial dysfunction. Circ Res 95:877-883
73. Li D, Singh RM, Liu L, Chen H, Singh BM, Kazzaz N, Mehta JL (2003) Oxidized-LDL through LOX-1 increases the expression of angiotensin converting enzyme in human coronary artery endothelial cells. Cardiovasc Res 57:238-243
74. Morawietz H, Rueckschloss U, Niemann B, Duerrschmidt N, Galle J, Hakim K, Zerkowski HR, Sawamura T, Holtz J (1999) Angiotensin II induces LOX-1, the human endothelial receptor for oxidized low-density lipoprotein. Circulation 100:899-902
75. Murase T, Kume N, Korenaga R, Ando J, Sawamura T, Masaki T, Kita T (1998) Fluid shear stress transcriptionally induces lectin-like oxidized LDL receptor-1 in vascular endothelial cells. Circ Res 83:328-333