Upregulation of endothelial receptor for oxidized low-density lipoprotein (LOX-1) in cultured human coronary artery endothelial cells by angiotensin II type 1 receptor activation

Circulation Research

Volumn 84, Issue 9, 1999, Pages 1043-1049

  Li, D Y ^a   Zhang, Y C ^a   Philips, M I ^a   Sawamura, T ^b   Mehta, J L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Angiotensin II; Endothelial cell; Oxidized LDL; Receptor

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN RECEPTOR; CELL RECEPTOR; LOSARTAN; LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CELL DAMAGE; CORONARY ARTERY; DNA SEQUENCE; ENDOTHELIUM CELL; GENE SEQUENCE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 0033553395     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.84.9.1043     Document Type: Article

References (42)

1. Witzum JL, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. J Clin Invest. 1991;88:23-28.
2. Schumacher M, Eber B, Tatzber F, Kaufmann P, Halwachs G, Fruhwald FM. Transient reduction of autoantibodies against oxidized LDL in patients with acute myocardial infarction. Free Radic Biol Med. 1995; 18:1087-1091.
3. 2 relaxations of the coronary vasculature and reduce contractile function in isolated rat hearts. Heart Vessels 1995;10: 249-257.
4. van-Boven AJ, Jukema JW, Paoletti R. Endothelial dysfunction and dyslipidemia: possible effects of lipid lowering and lipid modifying therapy. Pharmacol Res. 1994;29:261-272.
5. Bickel PE, Freeman MW. Rabbit aortic smooth muscle cells express inducible macrophage scavenger receptor messenger RNA that is absent from endothelial cells. J Clin Invest. 1992;90:1450-1457.
6. Kume N, Arai H, Kawai C, Kita T. Receptors for modified low density lipoproteins on human endothelial cells: different recognition for acetylated low-density lipoprotein and oxidized low-density lipoprotein. Biochim Biophys Acta. 1991;1091:63-67.
7. Sawamura T, Kume N, Aoyama T, Moriwaki H, Hoshikawa H, Aiba Y, Tanaka T, Miwa S, Katsura Y, Kita T, Masaki T. An endothelial receptor for oxidized low-density lipoprotein. Nature. 1997;386:73-77.
8. Mehta JL, Li DY. Identification and autoregulation of receptor for ox-LDL in cultured human coronary artery endothelial cells. Biochem Biophys Res Commun. 1998;248:511-514.
9. Murase T, Kume N, Korenaga R, Ando J, Sawamura T, Masaki T, Kita T. Fluid shear stress transcriptionally induces lectin-like oxidized LDL receptor-1 in vascular endothelial cells. Circ Res. 1998;83:328-333.
10. Kume N, Murase T, Moriwaki H, Aoyama T, Sawamura T, Masaki T, Kita T. Inducible expression of lectin-like oxidized LDL receptor-1 in vascular endothelial cells. Circ Res. 1998;83:322-327.
11. Feolde E, Vigne P, Frelin C. Angiotensin II receptor subtypes and biological responses in the rat heart. J Mol Cell Cardiol. 1993;25: 1359-1367.
12. Yang BC, Phillips MI, Ambuehl PEJ, Sheen LP, Mehta P, Mehta JL. Increase in angiotensin II type 1 receptor expression immediately following ischemia-reperfusion in isolated rat hearts. Circulation 1997;96: 922-926.
13. Timmermans PB, Smith RD. Angiotensin II receptor subtypes: selective antagonists and functional correlates. Eur Heart J 1994;15(suppl D):79-87.
14. 1 receptor and PKC activation. Am J Physiol. 1999;276:H786-H792.
15. Yamada T, Horiuchi M, Dzau VJ. Angiotensin II type 2 receptor mediates programmed cell death. Proc Natl Acad Sci U S A. 1996;93:156-160.
16. 2-receptor mediates inhibition of cell proliferation in coronary endothelial cells. J Clin Invest. 1995;95:651-657.
17. 1 receptor expression by hypercholesterolemia. Eur J Med Res. 1997;2:285-289.
18. Keidar S, Kaplan M, Hoffman A, Aviram M. Angiotensin II stimulates macrophages-mediated oxidation of low density lipoproteins. Atherosclerosis. 1995;115:201-215.
19. Keidar S, Attias J. Angiotensin II injection into mice increases the uptake of oxidized LDL by their macrophages via a proteoglycan-mediated pathway. Biochem Biophys Res Commun. 1997;239:63-67.
20. Li DY, Yang BC, Mehta JL. Oxidized low density lipoprotein induces apoptosis in cultured human coronary artery endothelial cells: role of PKC, PTK, bcl-2, and Fas. Am J Physiol 1998;275:H568-H576.
21. Chen LY, Mehta P, Mehta JL. Oxidized LDL decreases L-arginine uptake and nitric oxide synthase protein expression in human platelets: relevance of the effect of oxidized LDL on platelet function. Circulation 1996;93: 1740-1746.
22. Goldstein JL, Brown MS. Binding and degradation of low density lipoproteins by cultured human fibroblasts. J Biol Chem. 1974;249: 5153-5162.
23. Sarzani R, Opocher G, Dessi-Fulgheri P, Paci V, Cola G, Rocco S, Vianello B, Mantero F, Rappelli A. Expression of type 1 angiotensin II receptors in human aldosteronomas. Endocr Res. 1995;21:189-195.
24. Tsuzuki S, Ichiki T, Nakakubo H, Kitami Y, Guo DF, Shirai F, Inagami T. Molecular cloning and expression of the gene encoding human angiotensin II type 2 receptor. Biochem Biophys Res Commun 1994;200: 1449-1454.
25. Gräfe M, Auch-Schwelk W, Zakrzewiz A, Regitz-Zagrosek V, Bartsch P, Graf K, Loebe M, Gaehtgens P, Fleck E. Angiotensin II-induced leukocyte adhesion on human coronary endothelial cells is mediated by E-selectin. Circ Res. 1997;81:804-811.
26. 1 subtypes in renal afferent arterioles during chronic changes in sodium diet. J Clin Invest. 1997;99:1072-1081.
27. 2+ modulation. Circ Res. 1995;78:302-311.
28. Zhou X, Zhai X, Ashraf M. Preconditioning of bovine endothelial cells: the protective effect is mediated by an adenosine A2 receptor through a protein kinase C signaling pathway. Circ Res. 1996;78:73-81.
29. Liao L, Harris NR, Granger DN. Oxidized low density lipoproteins and microvascular responses to ischemia-reperfusion. Am J Physiol. 1996; 271:H2508-H2514.
30. Mehta A, Yang BC, Khan S, Hendricks JB, Stephen C, Mehta JL. Oxidized low-density lipoproteins facilitate leukocyte adhesion to aortic intima without affecting endothelium-dependent relaxation: role of P-selectin. Arterioscler Thromb Vasc Biol. 1995;15:2076-2083.
31. Regitz-Zagrosek V, Friedel N, Heymann A, Bauer P, Neuss M, Rolfs A, Steffen C, Hildebrandt A, Hetzer R, Fleck E. Regulation, chamber localization, and subtype distribution of angiotensin II receptors in human hearts. Circulation. 1995;91:1461-1471.
32. Regitz-Zagrosek V, Fielitz J, Dreysse R, Hildebrandt AG, Fleck E. Angiotensin receptor type 1 mRNA in human right ventricular endomyocardial biopsies: downregulation in heart failure. Cardiovasc Res 1997; 35:99-105.
33. 1-receptor expression. Am J Physiol. 1997;272:H2701-H2707.
34. Harada K, Komuro I, Hayashi D, Sngaya T, Murakami K, Yazaki Y. Angiotensin II type 1a receptor is involved in the occurrence of reperfusion arrhythmias. Circulation. 1998;97:315-317.
35. Nickenig G, Sachinidis A, Michaelsen F, Bohm M, Seewald S, Vetter H. Upregulation of vascular angiotensin II receptor gene expression by low density lipoprotein in vascular smooth muscle cells. Circulation. 1997; 95:473-478.
36. Pitt B, Segal R, Martinez FA, Meurers G, Cowley AJ, Thomas I, Deedwania PC, Ney DE, Snavley DB, Chang PI. Randomized trial of losartan versus captopril in patients over 65 with heart failure: evaluation of losartan in the elderly study (ELITE). Lancet. 1997;349:747-752.
37. Scandinavian Simvastatin Survival Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study. Lancet. 1994;344:1383-1385.
38. Berkenboom G, Langer I, Carpentier Y, Grosfils K, Fontaine J. Ramipril prevents endothelial dysfunction induced by oxidized low-density lipoproteins: a bradykinin-dependent mechanism. Hypertension 1997;30(3 Pt 1):371-376.
39. Nagas M, Hirose S, Fujita T. Unique repetitive sequence and unexpected regulation of expression of rat endothelial receptor for oxidized low density lipoproteins (LOX-1). Biochem J. 1998;330:1417-1422.
40. Wielbo D, Sernia C, Gyurko R, Phillips MI. Antisense inhibition of hypertension in the spontaneously hypertensive rat. Hypertension. 1995; 25:314-319.
41. Dimmeler S, Rippmann V, Weiland U, Haendeler J, Zeiher AM. Angiotensin II induces apoptosis of human endothelial cells: protective effect of nitric oxide. Circ Res. 1997;81:970-976.
42. Rangaswamy S, Penn MS, Saidel GM, Chisolm GM. Exogenous oxidized low-density lipoprotein injures and alters the barrier function of endothelium in rats in vivo. Circ Res. 1997;80:37-44.