Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling

Journal of Cellular and Molecular Medicine

Volumn 16, Issue 11, 2012, Pages 2736-2744

  Ofek, Keren ^a   Schoknecht, Karl ^b   Melamed Book, Naomi ^a   Heinemann, Uwe ^b   Friedman, Alon ^c   Soreq, Hermona ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Acetylcholinesterase; Fluoxetine; Ischaemic stroke; Muscarinic receptors; Nitric oxide; Vasodilatation

Indexed keywords

ACETYLCHOLINESTERASE; ATROPINE; CALCIUM; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUOXETINE; HEAT SHOCK PROTEIN 90; MECAMYLAMINE; METHYSERGIDE; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NOS3 PROTEIN, RAT; SEROTONIN; SEROTONIN UPTAKE INHIBITOR;

ANIMAL; ARTERIOLE; ARTICLE; BRAIN CORTEX; CELL CULTURE; CEREBROVASCULAR ACCIDENT; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; MALE; METABOLISM; PHYSIOLOGY; RAT; REPERFUSION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; VASCULARIZATION; VASODILATATION;

ACETYLCHOLINESTERASE; ANIMALS; ARTERIOLES; ATROPINE; CALCIUM; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOXETINE; HSP90 HEAT-SHOCK PROTEINS; MALE; MECAMYLAMINE; METHYSERGIDE; MUSCARINIC ANTAGONISTS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; REPERFUSION; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; SIGNAL TRANSDUCTION; STROKE; VASODILATION;

RATTUS;

EID: 84868089366     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2012.01596.x     Document Type: Article

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